著者
古賀 俊貴
出版者
生命の起原および進化学会
雑誌
Viva Origino (ISSN:09104003)
巻号頁・発行日
vol.50, no.3, pp.5, 2022 (Released:2022-12-27)
参考文献数
90

Since the detection of extraterrestrial amino acids in the Murchison meteorite, dramatic improvements in chromatographic techniques with mass spectrometry over the past half century have revealed the presence of a wide variety of organic compounds of extraterrestrial origin in carbonaceous meteorites. The possibility that biologically relevant compounds (amino acids, sugars, nucleobases, etc.) contained in extraterrestrial materials were transported to the early Earth and contributed to the primordial molecular evolution has been discussed in many previous works. In this sense, organic analysis of carbonaceous meteorites provides unique geological evidence for understanding the distributions of organic molecules that may have been available on the prebiotic Earth. Equally important, determining how the abiotic molecules in meteorites were formed in the Solar system will provide important clues for considering the pristine chemical reactions that proceeded on the early Earth. Here, this review overviews comprehensive reports on the distributions and characteristics of amino acids, sugars, and nucleobases found in carbonaceous meteorites with the aim of sharing the knowledge on pre-biologically relevant molecules of extraterrestrial origin.
著者
Toshiki Fukuzaki Sawako Ooba Kenji Yamaguchi Ryuko Matsuda Noriyuki Namba
出版者
Tottori University Medical Press
雑誌
Yonago Acta Medica (ISSN:13468049)
巻号頁・発行日
vol.66, no.1, pp.36-47, 2023 (Released:2023-02-20)
参考文献数
26
被引用文献数
1

Background Achieving an optimal work-life balance (WLB) is an important social issue not only for workers in general but also for doctors due to the shortage of women doctors. The present study aims to survey doctors’ WLB and their use of household chore support services (HCSS).Methods A questionnaire survey was conducted with doctors working in Tottori Prefecture and a total of 289 responses (212 men, 77 women) were obtained and analyzed. To examine the relationship between gender and satisfaction with working patterns or with life for WLB, as well as the use of HCSS, a chi-squared test was conducted. Furthermore, a chi-squared test was conducted including age, marital status, whether or not they have preschool-aged children, and type of institution the participant worked.Results A significant difference was found in type of institution the participant worked regarding satisfaction with work patterns and life. The proportion of those who have used HCSS was 12.5% of the total sample and was significantly higher for women than men (men: 8.5%; women: 23.4%). Regarding the reason to use HCSS, “to reduce the burden of household chores and childcare” and “to secure time for work” were most common with the same proportions, and amongst women, “to secure time for work” was the highest.Conclusion Doctors working at a university hospital could have different work patterns and satisfaction with life compared to those working at other types of medical institutions. Additionally, the demand for HCSS was particularly high among women doctors, which suggests that HCSS may be used to reduce the burden of household chores and childcare, as well as to create time for work.
著者
Yuki Ishinoda Nobuyuki Masaki Yasuhiro Hitomi Akira Taruoka Akane Kawai Midori Iwashita Yusuke Yumita Kazuki Kagami Risako Yasuda Yasuo Ido Takumi Toya Yukinori Ikegami Takayuki Namba Yuji Nagatomo Koji Miyazaki Bonpei Takase Takeshi Adachi
出版者
Japan Atherosclerosis Society
雑誌
Journal of Atherosclerosis and Thrombosis (ISSN:13403478)
巻号頁・発行日
pp.63779, (Released:2023-02-11)
参考文献数
55
被引用文献数
4

Aims: The long-term prognostic value of the bioavailability of L-arginine, an important source of nitric oxide for the maintenance of vascular endothelial function, has not been investigated fully. We therefore investigated the relationship between amino acid profile and long-term prognosis in patients with a history of standby coronary angiography. Methods: We measured the serum concentrations of L-arginine, L-citrulline, and L-ornithine by high-speed liquid chromatography. We examined the relationship between the L-arginine/L-ornithine ratio and the incidence of all-cause death, cardiovascular death, and major adverse cardiovascular events (MACEs) in 262 patients (202 men and 60 women, age 65±13 years) who underwent coronary angiography over a period of ≤ 10 years.Results: During the observation period of 5.5±3.2 years, 31 (12%) patients died, including 20 (8%) of cardiovascular death, while 32 (12%) had MACEs. Cox regression analysis revealed that L-arginine/L-ornithine ratio was associated with an increased risk for all-cause death (unadjusted hazard ratio, 95% confidence interval) (0.940, 0.888–0.995) and cardiovascular death (0.895, 0.821–0.965) (p<0.05 for all). In a mod el adjusted for age, sex, hypertension, hyperlipidemia, diabetes, current smoking, renal function, and log10-transformed brain natriuretic peptide level, cardiovascular death (0.911, 0.839–0.990, p=0.028) retained an association with a low L-arginine/ L-ornithine ratio. When the patients were grouped according to an L-arginine/L-ornithine ratio of 1.16, the lower L-arginine/L-ornithine ratio group had significantly higher incidence of all-cause death, cardiovascular death, and MACEs. Conclusion: A low L-arginine/L-ornithine ratio may be associated with increased 10-year cardiac mortality.
著者
山名 章二
出版者
大妻女子大学人間生活文化研究所
雑誌
人間生活文化研究 (ISSN:21871930)
巻号頁・発行日
vol.2019, no.29, pp.119-128, 2019-01-01 (Released:2020-01-24)

これは草稿転写の報告だが, 解読に詰めも残しており, 資料の紹介ノートと呼ぶのがふさわしい. 原本は日本放送協会のラジオ放送劇の脚本で, 金沢市在石川近代文学館に北村喜八関連資料の一として所蔵されている. 放送は日本の連合国軍への降伏からほぼ三年後, 1948年8月であった. 築地小劇場に始まり演劇界で広範に活躍し, 英米さらにドイツの文学作品を幅広く翻訳出版, 数多の著書を公刊, 晩年には日本の劇界を代表して国際的に活動し, その中でオニールにも上演に翻訳に深く取り組み続け,文通もあった北村喜八の執筆による. その内容はオニールが波乱の青年期を終え演劇に確固たる基盤を築く頃をセリフ劇形式で跡付け, その後の主要戯曲および近作情報を紹介し, オニールの一層の活躍への期待も込められている. 1946年初演の The Iceman Cometh はいち早く触れられているが, 没後25年を経て公開するよう遺言されることになる Long Day’s Journey into Night への言及はない.当然ながら. アメリカ文化に大いに関心を寄せその影響も色濃い1920年代, 30年代の日本がアメリカ演劇を受容した熱気を戦後に復興しようとする意欲をも窺わせる資料である.
著者
岡部 信彦
出版者
一般社団法人 日本内科学会
雑誌
日本内科学会雑誌 (ISSN:00215384)
巻号頁・発行日
vol.91, no.10, pp.2845-2849, 2002-10-10 (Released:2008-06-12)
参考文献数
8
出版者
自由民主党本部
巻号頁・発行日
0000

1 0 0 0 鉄鋼界

著者
日本鉄鋼連盟
出版者
日本鉄鋼連盟
巻号頁・発行日
1951
著者
山辺 賢一郎 汪 群慧 成田 純也 吉田 晋也 森下 正人 白井 義人 尾川 博昭
出版者
Japan Society of Civil Engineers
雑誌
環境工学研究論文集 (ISSN:13415115)
巻号頁・発行日
vol.37, pp.81-88, 2000-11-13 (Released:2011-06-27)
参考文献数
14

To develop a garbage recycling system including garbage disposal, lactic acid and biodegradable plastics production, the preservation and deodorization of garbage during storage and the explication of their mechanisms are very important. The changes of counts of viable cell in garbage collected from university's dining hall during the storage were observed. In spite of seasons, lactic acid bacteria became preferential bacteria after the garbage was stored for 24 hours. On the contrary, coliforms and clostridia that are indexes of putrefaction and pollution remarkably decreased. The coliforms were not detected after the 72- or 96- hour storage. No food poisoning bacteria, such as staphylococcus aureus and bacillus cereus, were detected after the 24 hours storage. From the results of experiment adding the staphylococcus aureus to the garbage, it was proved that the lactic acid bacteria also easily became preferential bacteria even if food poisoning bacteria gained predominance at the beginning of the storage. It is clear from this study that lactic acid fermentation during the storage process inhibits the growth of putrefactive bacteria and food poisoning bacteria, which, as a result, makes it possible to realize the preservation and deodorization of garbage.
著者
大塚 篤司 生駒 晃彦
出版者
公益社団法人 日本皮膚科学会
雑誌
日本皮膚科学会雑誌 (ISSN:0021499X)
巻号頁・発行日
vol.133, no.2, pp.227-241, 2023-02-20 (Released:2023-02-20)
参考文献数
14

アトピー性皮膚炎(Atopic dermatitis;AD)の影響や治療について,医師と患者の認識を調べるため,医師209名と患者716名を対象にオンラインアンケート調査を実施した.その結果,患者は医師が考えるほどには日常生活の上で制限を受けていると感じておらず,心理・精神的にも困っていない可能性が示された一方で,医師よりも症状を改善させたい思いが強いことが示された.患者の意図を汲んだAD治療の実現のために,ADに対する医師と患者の認識のギャップを解消する必要性が示唆された.
著者
松立 吉弘
出版者
日本臨床皮膚科医会
雑誌
日本臨床皮膚科医会雑誌 (ISSN:13497758)
巻号頁・発行日
vol.38, no.5, pp.754-756, 2021 (Released:2022-01-20)
参考文献数
8
被引用文献数
1

COVID-19ワクチンによる副反応は様々なものがあるが,遅延型投与部位反応(COVID arm)は十分に認識されていない.COVID-19ワクチンの初回接種後1週間程度で生じるそう痒を伴う紅斑,硬結,圧痛を特徴とし,通常4~5日程度で消退する.2回目の接種でも同程度もしくは軽度の反応がみられることが多く,初回より出現までの期間が短い傾向にある.アナフィラキシーや蕁麻疹などの即時型過敏反応とは異なり,以後のワクチン接種は禁忌ではない.今後の集団接種の拡大に伴い,診察する機会が増えると思われる.本症状を認識しておく必要があると考え,経験した2例を報告する.