著者
自見 厚郎 堀江 昭夫 八巻 敏雄
出版者
学校法人 産業医科大学
雑誌
Journal of UOEH (ISSN:0387821X)
巻号頁・発行日
vol.4, no.3, pp.327-331, 1982-09-01 (Released:2017-04-11)

植物ホルモンの一つである天然オーキシンの主成分は indoleacetic acid (IAA) である. IAAは正常ヒト尿のほか消化管癌組織にも存在し, また動・植物細胞の増殖に関与する (Yamaki et al., 1979). ヒト子宮頸癌由来のHeLa細胞に対するIAAの増殖効果とその拮抗物質PCIB (parachlorophenoxy-iso-butyric acid) の増殖抑制効果をin vitroにおいて検討して, 次の結論がえられた. 1) IAAに増殖効果がみられた. 2) PCIBにIAA, FBS (fetal bovine serum, ウシ胎児血清) に対する拮抗作用がみられた. 3) FBS添加培地の方が細胞増殖作用は優れていた. HeLa細胞はヒト子宮頸癌由来の安定した細胞である. IAAが胃, 食道などの消化管癌などに多く含まれている事実を考え併せると, 癌細胞の増殖にIAAの関与することは想像に難くないと思われる. しかし, 厚い細胞壁を持つ植物細胞と持たない動物細胞に同様の増殖作用がIAAによってみられることから, その構造上の差異に関係しない共通のIAAの作用機序を考える必要がある.
著者
Hideki NAKAJIMA Shigetoshi SHIMIZU Takuro TSUCHIYA Hidenori SUZUKI
出版者
The Japan Neurosurgical Society
雑誌
NMC Case Report Journal (ISSN:21884226)
巻号頁・発行日
vol.10, pp.33-39, 2023-12-31 (Released:2023-02-23)
参考文献数
24

Blood blister aneurysms (BBAs) or pseudoaneurysms (PAs) in the internal carotid artery (ICA) have fragile necks; therefore, conventional neck clipping is difficult. The standard treatment for BBAs or PAs is trapping with high or low flow bypass. However, there is no consensus on whether or not anterior clinoidectomy should be performed together. Two patients with ruptured ICA PA (anterior protrusion) or BBA (posterior protrusion) were presented to our hospital. Complete trapping was safely performed for both types of aneurysms via extradural anterior clinoidectomy and the extradural approach with dural incision. The advantages of the procedure are 1) safe proximal clipping, 2) early identification of the ICA C3 portion, 3) minimized frontal lobe retraction, 4) optic canal opening to allow mobility of the optic nerve, and 5) dural ring incision to allow mobility of the ICA.
著者
小屋 多恵子
出版者
日本実用英語学会
雑誌
日本実用英語学会論叢 (ISSN:1883230X)
巻号頁・発行日
vol.2006, no.12, pp.1-18, 2006-09-15 (Released:2010-03-12)
参考文献数
30

The purpose of this paper is to examine the possibility that the notion of collocation competence will change from the one which only native speakers of English can establish or confirm to the one which all the educated English speakers can accept and share. To this purpose, a survey was conducted to ascertain whether some native speakers of English, advanced EFL learners in Asian countries and Japanese returnees would accept unclear answers produced by 130 Japanese university students. The main result was that advanced EFL learners in Asian countries and Japanese returnees had a wider acceptance of collocations than did native speakers of English. This finding would indicate that we should contribute to the promotion of acceptable English collocations which can be understood and shared by all the educated speakers of any variety.
著者
山田 周二
出版者
公益社団法人 日本地理学会
雑誌
地理学評論 Series A (ISSN:18834388)
巻号頁・発行日
vol.93, no.6, pp.443-463, 2020-11-01 (Released:2023-02-19)
参考文献数
18

本研究は,約30 mメッシュのDEMを用いて,北緯60度~南緯60度のすべての陸地にある山頂を抽出した.半径1 kmの円内の中心点が,その円内で最も標高が高い場合に,その中心点を山頂と定義し,その円内の起伏と平均傾斜を計測した.その結果,起伏が1,500 m以上で平均傾斜が45°以上と,きわめて険しい山頂のほとんどは,ヒマラヤ山脈に分布しており,それに次いで険しい,起伏が500 m以上で平均傾斜が35°以上の山頂は,アルプス・ヒマラヤ地域および環太平洋地域,中央アジア,アフリカ大地溝帯といった地殻変動や火山活動が活発な地域に分布することがあきらかになった.また,起伏が500 m以上で平均傾斜が35°未満の山頂は,上記の地域に加えて,大陸縁に分布すること,そして,起伏が500 m未満で平均傾斜が35°以上の山頂は,東アジア南部の塔状カルストに限られること,があきらかになった.
著者
Takumi HOSHIMARU Fugen TAKAGI Yuichiro TSUJI Ryokichi YAGI Ryo HIRAMATSU Masahiro KAMEDA Naosuke NONOGUCHI Motomasa FURUSE Shinji KAWABATA Toshihiro TAKAMI Masahiko WANIBUCHI
出版者
The Japan Neurosurgical Society
雑誌
NMC Case Report Journal (ISSN:21884226)
巻号頁・発行日
vol.10, pp.27-32, 2023-12-31 (Released:2023-02-23)
参考文献数
21

Primary germ cell tumors of the central nervous system (CNS) typically occur in the neurohypophysis, hypothalamus, or pineal gland and rarely in the spinal cord. We report a case of a spinal intramedullary tumor, which was first detected on magnetic resonance imaging (MRI) 41 months after the initial symptoms, with a verified pathological diagnosis of germinoma. The initial symptom was an abnormal sensation in the left plantar region that gradually worsened, resulting in severe sensory disturbance, difficulty in standing, and even bladder rectal disturbance. Repeated MRI after the onset failed to provide an imaging diagnosis. The MRI was performed 41 months after the onset and revealed a previously undiagnosed, contrast-enhancing spinal intramedullary neoplastic lesion at the Th11-12 level. Gross total resection of the tumor was successfully performed, and the pathology confirmed the diagnosis of pure germinoma. Postoperative chemotherapy, followed by local radiation, was successfully administered. Among primary germinomas of the CNS, occult germinoma that lacks imaging findings suggestive of tumors in the early stages of onset and becomes apparent over time is often reported as a primary neurohypophyseal germinoma, particularly in adolescents presenting with diabetes insipidus. In the present case, the lesion appeared to correspond to a primary occult germinoma of the intramedullary spinal cord.
著者
宮地 慎 小林 良次 野中 和久
出版者
公益社団法人 日本畜産学会
雑誌
日本畜産学会報 (ISSN:1346907X)
巻号頁・発行日
vol.81, no.2, pp.161-167, 2010-05-25 (Released:2010-11-25)
参考文献数
19

乳牛の胎盤摂取が泌乳初期の採食量,乳生産量,採食行動に与える影響および胎盤の第一胃内分解特性を明らかにするため,経産牛を10頭供試し,分娩後に胎盤を摂取させる区(PF区)と無摂取区(NF区)に分け,分娩前1週から分娩後4週まで採食量,採食行動,乳生産量,血液性状を測定した.また,胎盤の第一胃内分解率については第一胃カニューレ装着去勢牛を供試しin situ法で測定した.採食量,体重,乳量および乳成分は処理間で差はなかった.分娩後7日間のミール回数はPF区がNF区より多く,分娩後10日間のミールサイズはPF区がNF区より小さく,継続時間は短かった.分娩後2週以降ではミールパラメータに処理間で差はなかった.血中総ケトン体および遊離脂肪酸濃度は分娩後5日間でPF区がNF区より低かった.また胎盤の第一胃内乾物分解率は5日間で70.9%に達するが,それ以降は増加しなかった.以上より,分娩後に胎盤を摂取した乳牛の泌乳初期の採食量,乳生産量は無摂取の乳牛と同様に増加することが示唆された.
著者
Takayuki KAKIMOTO Satoshi MURAI Noboru KUSAKA Fukiko BABA Yohei INOUE Hayato MIYAKE Masato KAWAKAMI Yukei SHINJI Hisakazu ITAMI Shinji OTSUKA Tsukasa NISHIURA Kenji KAWAMOTO Tsuyoshi YAMAMOTO Nobuhiko KIMURA Kotaro OGIHARA
出版者
The Japan Neurosurgical Society
雑誌
NMC Case Report Journal (ISSN:21884226)
巻号頁・発行日
vol.10, pp.21-25, 2023-12-31 (Released:2023-02-23)
参考文献数
11

A 78-year-old man underwent a tracheostomy after embolization for a dural arteriovenous fistula. Seventy days after tracheostomy, arterial bleeding appeared through the tracheal stoma. The bleeding stopped spontaneously. However, two days later, arterial bleeding reappeared, and he was diagnosed with a tracheo-innominate artery fistula (TIF). He then underwent urgent endovascular covered stent placement. After the procedure, there was no bleeding. TIF can be a fatal complication after tracheostomy and it is generally treated with open chest surgery. However, a successful endovascular treatment for TIF has recently been reported and may yield better results.
著者
佐野 公俊 加藤 庸子 安部 雅人 笠間 睦 神野 哲夫
出版者
一般社団法人 日本脳卒中の外科学会
雑誌
脳卒中の外科 (ISSN:09145508)
巻号頁・発行日
vol.19, no.4, pp.595-597, 1991-12-20 (Released:2012-10-29)
参考文献数
8
被引用文献数
3 2

In cases of difficult aneurysms the temporary occlusion of blood flow makes the operation easy; however, ischemic damage of the brain must always be considered. Temporary clipping of the parent artery is easy, but ischemic damage may be severe.On the other hand, a tentative clip which is put on the aneurysm either partially or totally, has the following merits:1) Preparation of the aneurysm is easy and safe.2) There is less ischemic damage.But there are the following demerits:1) The part of the aneurysm on which a tentative clip is put should be prepared.2) At the time of tentative clipping the back side of the aneurysm cannot be seen.Temporary clipping and tentative clipping, each has its own merits and demerits.We have to approach aneurysms on the base of sufficient knowledge.
出版者
講談社
巻号頁・発行日
0000
著者
KOH GOTOH
出版者
The Japanese Circulation Society
雑誌
JAPANESE CIRCULATION JOURNAL (ISSN:00471828)
巻号頁・発行日
vol.40, no.7, pp.753-768, 1976-08-20 (Released:2008-04-14)
参考文献数
20
被引用文献数
35 40

The conduction system of seven cases died of the so-called "Pokkuri disease", was histopathologically studied with serial sectioning method. Fibrosis with a significant reduction of conduction fibers was observed in the sinoatrial node and unction between the node and atrial muscle fibers in 6 cases. Abnormal course and branching of the sinus node artery was seen in 6 cases of which 3 had no penetration o fits main branch into the node. Some pathological lesions exsisted in the atrioventricular conduction system in 4 cases: 2 had fibrotic lesion in the distal bundle of His and proximal left and right bundle branches which were sandwiched between the abnormal conal muscle and the summit of ventricular septum. Remaining 2 had lipomatous partial interruption in the mid- and distal bundle of His. Simultaneous involvement of sinoatrial node and the atrioventricular conduction system was observed in 4 cases. One of such cases showed abnormal ECG consisted of a left axis deviation and right bundle branch block. As a conclusion, pathological lesions in the conduction system are revealed in more than half of cases of "Pokkuri disease". The pathgenesis seems to be related to minor anomalies such as abnormal sinus node artery, abnormal conal muscle situation.
著者
北原 曜
出版者
一般社団法人 日本治山治水協会
雑誌
水利科学 (ISSN:00394858)
巻号頁・発行日
vol.53, no.6, pp.11-37, 2010-02-01 (Released:2017-08-30)
参考文献数
30
被引用文献数
9