著者
青 未空 宮脇 尚志 田中 清
出版者
公益社団法人 日本ビタミン学会
雑誌
ビタミン (ISSN:0006386X)
巻号頁・発行日
vol.93, no.11, pp.478-484, 2019-11-25 (Released:2020-11-30)

Objective: Recently, even vitamin B 12 (B 12 ) insufficiency, which is milder than B 12 deficiency, has been reported to increase various diseases risks through hyperhomocysteinemia. Therefore, we investigated B 12 intake by age using the data of the National Health and Nutrition Survey (NHNS). Method: We re-analyzed the data of the NHNS 2015. Data from 6941 subjects out of 8583 subjects, after excluding subjects under the age of 18, female subjects with pregnancy or breastfeeding, and subjects with energy intake over the average ± 2SD, were analyzed. Results: The percentage of subjects whose B 12 intake was below the estimated average requirement (EAR) was 30.7% for those under 50 years old and 19.1% for those equal to or higher than 50 years old. The presence of raw seafood, processed seafood, and viscera mainly contributed to B 12 intake. The percentage of subjects eating raw or processed seafood increased with increasing age. Conclusions: B 12 intake was less than EAR in a substantial percentage of subjects, especially those under 50 years old. Low seafood intake could be considered as this cause. Examination and research approach considering age for B 12 intake are desirable in future.
著者
Young A Lee Eun Ju Cho Takako Yokozawa
出版者
The Pharmaceutical Society of Japan
雑誌
Biological and Pharmaceutical Bulletin (ISSN:09186158)
巻号頁・発行日
vol.31, no.6, pp.1265-1269, 2008-06-01 (Released:2008-06-01)
参考文献数
41
被引用文献数
44 56

8-Hydroxy-2′-deoxyguanosine (8-OHdG), one of the most abundant oxidative DNA adducts, is used as an indicator of oxidative DNA damage associated with aging. Among homologs of the silent information regulator (Sir), sirtuin 1 (SIRT1) is suggested as a regulator of the apoptotic response to DNA damage. Since it has been suggested that the aging process can be delayed by the attenuation of oxidative damage such as DNA damage or SIRT1 modulation, we focused on the protective effect against cellular oxidative damage of persimmon peel, a proanthocyanidin-rich food, in relation to its level of polymerization. We confirmed that 8-OHdG expression in TIG-1 human fibroblasts was increased by treatment with 300 μM H2O2 for 2 h. On the other hand, the nuclear SIRT1 level was decreased in H2O2-treated as compared with non-pretreated cells. However, pretreatments with polymers and oligomers led to a decrease in 8-OHdG and elevation in nuclear SIRT1 expression in a concentration-dependent manner. In particular, oligomers exerted a stronger effect. The present study supports the protective potential of proanthocyanidin from persimmon peel against oxidative damage under the aging process, and suggests that the polymerization of proanthocyanidin plays an important role in retarding aging in a cellular senescence model.
著者
東 秀雄 村山 繁雄 簗瀬 正明 田部井 菊子
出版者
公益社団法人 日本水産学会
雑誌
日本水産学会誌 (ISSN:00215392)
巻号頁・発行日
vol.20, no.8, pp.741-749, 1954-12-25 (Released:2008-02-29)
参考文献数
11
被引用文献数
1 1

Two fillets which had similar properties to each other as shown in Table 1 were prepared from several samples of Mackerel for the present study. One fillet of the sample was protected from rusting by treating with Butyl-hydroxyanisol (B. H. A.) as antioxidant and with NaCl before drying and the other, control, salted without antioxydant, then dried. When standing for 6-23 days after drying, each fillet was separated to three layers: inner surface, skin layer and interior layer between them, of which to examine lipids. From the results represented in Tables 3-8, the following facts have been revealed. 1) When salted dried fish is disolored, the lipids transfer from the skin layer to the inner surface (Fig. 1, Tables 7, 8). 2) Lipids of the inner surface of dried fish which has been discolored is remarkably deteriorated, whereas lipids of the interior layer or the skin layer do not suffer so much variation (Tables 3-6). 3) It seems that during the discoloration of dried fish various conjugated double bonds are formed in fatty acids of the surface lipids due to the transition of their proper double bonds (Figs. 2, 3).
出版者
北京大學出版部
巻号頁・発行日
1923
著者
田中 瑠莉
出版者
日本文化人類学会
雑誌
日本文化人類学会研究大会発表要旨集 日本文化人類学会第55回研究大会 (ISSN:21897964)
巻号頁・発行日
pp.D13, 2021 (Released:2021-10-01)

本発表では、京都市動物園の事例をもとに動物園の飼育動物(動物園動物)と人の関係について考察する。動物園において、それぞれの動物は「個」として扱われる一方で、動物を「擬人化」することは批判的に捉えられる。両者の差異に着目し、動物園の飼育動物を人と対等な存在として扱うことの内実と、飼育している個体との関係形成の根底にある規範について動物の人格に関する議論を参照し考察を試みる。
著者
(唐) 陸徳明撰 黄焯彙校
出版者
中華書局
巻号頁・発行日
2006
著者
黄焯撰
出版者
中華書局
巻号頁・発行日
1980
著者
Toshihide Izumida Yosikazu Nakamura Yukihiro Sato Shizukiyo Ishikawa
出版者
Japan Epidemiological Association
雑誌
Journal of Epidemiology (ISSN:09175040)
巻号頁・発行日
vol.32, no.3, pp.145-150, 2022-03-05 (Released:2022-03-05)
参考文献数
40
被引用文献数
1 4

Background: Sleeping pills are widely used for sleep disorders and insomnia. This population-based study aimed to evaluate the association between the use of sleeping pills and metabolic syndrome (MetS) and metabolic components in an apparently healthy Japanese cohort.Methods: We examined baseline cross-sectional data from the JMS-II Cohort Study. The criteria for MetS and its components were based on The National Cholesterol Education Program Adult Treatment Panel III. Sleep habits including the sleep duration of the subjects and the frequency of sleeping pill use were obtained using The Pittsburgh Sleep Quality Index questionnaire. For different sleep durations, the association between sleeping pill use and MetS was assessed. Odds ratios (ORs) and their 95% confidence intervals (CIs) were estimated using multiple logistic regression models to quantify this association.Results: Our study included 6,153 individuals (mean age, 63.8 [standard deviation 11.2] years), and 3,348 (54.4%) among them were women. The association between sleep duration and MetS was an inverted J-shaped curve among sleeping pill users and a J-shaped curve among non-users. After adjustment for various confounders, less than 6 h of sleep among sleeping pill users was associated with increased rates of MetS (<6 h, OR 3.08; 95% CI, 1.29–7.34]). The frequency of sleeping pill use in individuals with short sleep duration showed a positive association with the prevalence of MetS and its components.Conclusions: Sleeping pill users with a short sleep duration had a 3-fold higher chance of having MetS than non-users with a short sleep duration.
著者
黒木 朋興
出版者
特定非営利活動法人 頸城野郷土資料室
雑誌
頸城野郷土資料室学術研究部研究紀要 (ISSN:24321087)
巻号頁・発行日
vol.5, no.1, pp.1-24, 2020 (Released:2020-03-17)
参考文献数
19

日本語で政教分離と訳されるフランスのライシテをキーワードとして、マラルメの詩学を読解し、更に19世紀末以降に共和政を開始したフランスの民主主義における神と宗教における問題を考察する。キリスト教への信仰を捨てたマラルメは、神を代換する機能を芸術に託すことによって、神なき時代の社会と芸術のあり方を探究し、20世紀には多くの前衛芸術に絶大なる影響を与えた。また、フランスは18世期末の大革命により王政を廃止して、政治からカトリック教会の影響を切り離すことで共和政を開始し、世界の民主主義に大きな影響を与えた。この二つのテーマはともに、神中心から人間を主役にした仕組みへの移行というライシテの思想に基づいている。というわけで、前衛の理論的支柱となったマラルメの詩学と西洋近代民主義が標榜する普遍性がどの程度有効なのを探るべく、ライシテをキーワードにこの両者の分析を行った。まずはフランスのライシテの背景としてカトリックの思想を受肉とフェティシズムの観点から解説し、更にマラルメがライシテについて言及している断章を読解することによって、フランスのライシテが抱える困難な状況を分析した。それを通して、西洋近代民主主義の問題点を明らかにし、その普遍性について改めて考えてみた。
著者
石田 惣
出版者
日本貝類学会
雑誌
Venus (Journal of the Malacological Society of Japan) (ISSN:13482955)
巻号頁・発行日
vol.78, no.3-4, pp.105-118, 2020-09-25 (Released:2020-10-10)
参考文献数
50

Citizen science is a powerful way to survey the distribution of alien species in a broader area and is effective in promoting public awareness. I conducted a citizen science project to survey the distribution of the alien Decollate Snail Rumina decollata in Osaka, central Honshu, Japan. This species has spread over the Prefecture in recent years. As a first step I set up ‘train station survey' in which each volunteer selects a train station in Osaka and looks for the snail on foot for 1 hour within a 1-km radius from the station. This survey revealed that the snail inhabits mainly the Senboku area (the northern part of southern Osaka). The next step aimed to investigate in greater detail the snail's distribution in the Senboku area using the following methods: 1) Grid survey: each volunteer selects a focal grid (conforming to the third-order-unit grid defined by the Statistics Bureau of Japan, ca. 1 km square) and looks for the snail within the grid for 1 hour. 2) Gathering observations from residents: fliers are handed out to municipal elementary school children and library visitors in the Senboku area, or a social networking service is used to gather snail observations from the residents. Integration of the results of these surveys revealed that the Decollate Snail occurred in fifty-one third-order-unit grids in Osaka Prefecture at the end of November 2019. Information from residents indicated that the snail had been introduced between 2000 and 2010 in Osaka and that one probable dispersal route was via gardening or agricultural materials such as soil or seedlings. The train station survey is an effective way to screen a high-density area. Observations were provided continuously for four months by residents who had found out about this project from the fliers distributed to the elementary school children. This suggests that fliers in schools may be effective in collecting observations of alien species.
著者
Silvano Gallus Alessandra Lugo Xiaoqiu Liu Elisa Borroni Luke Clancy Giuseppe Gorini Maria José Lopez Anna Odone Krzysztof Przewozniak Olena Tigova Piet A. van den Brandt Constantine Vardavas Esteve Fernandez the TackSHS Project Investigators
出版者
Japan Epidemiological Association
雑誌
Journal of Epidemiology (ISSN:09175040)
巻号頁・発行日
vol.32, no.3, pp.139-144, 2022-03-05 (Released:2022-03-05)
参考文献数
30
被引用文献数
8 28

Background: Heated tobacco products (HTP) are new forms of tobacco consumption with limited information available on their use among the general population. Our objective was to analyze the prevalence and associations of use of HTP across 11 countries in Europe.Methods: Within the TackSHS Project, in 2017–2018 we conducted a cross-sectional study with information on HTP use in the following countries: Bulgaria, England, France, Germany, Greece, Italy, Latvia, Poland, Portugal, Romania and Spain. In each country, face-to-face interviews were performed on a representative sample of around 1,000 subjects aged ≥15 years, for a total of 10,839 subjects.Results: Overall, 27.8% of study participants were aware of HTPs, 1.8% were ever HTP users (ranging from 0.6% in Spain to 8.3% in Greece), and 0.1% were current users. Men were more frequently HTP ever users than women (adjusted odds ratio [aOR] 1.47; 95% confidence interval [CI], 1.11–1.95). Ever HTP use was inversely related to age (P for trend <0.001) and more frequent in ex-smokers (compared with never smokers, aOR 4.32; 95% CI, 2.69–6.95) and current smokers (aOR 8.35; 95% CI, 5.67–12.28), and in electronic cigarette past users (compared with never users, aOR 5.48; 95% CI, 3.46–8.68) and current users (aOR 5.92; 95% CI, 3.73–9.40).Conclusions: In 2017–2018, HTP use was still limited in Europe among the general population; however, the dual use of these products, their high use among younger generations, and the interest of non-smokers in these products are worrying and indicate the need for close monitoring in terms of prevalence and the characteristics of users.
著者
生長 幸之助
出版者
日本薬学図書館協議会
雑誌
薬学図書館 (ISSN:03862062)
巻号頁・発行日
vol.65, no.4, pp.182-187, 2020-10-31 (Released:2022-04-13)
参考文献数
19

現代におけるプレプリント投稿とは,査読前論文をインターネット上に公開する学術出版形態を指す。現行査読システムが内包する諸問題の解決や,オープンサイエンス潮流の後押し,コロナ禍における成果共有の迅速化などから,昨今,特に大きな注目を集めている。ChemRxiv(ケムアーカイブ)は,2017年に運用が開始された化学系プレプリントサーバである。2019年には日本化学会も運営サポートに関わり,我が国の化学分野でもプレプリント活用の活発化が期待される。本稿ではプレプリントの概論を紹介したのち,化学領域におけるプレプリント時代の学術出版スタイルについて論じていく。