著者

芳原 準男 外間 惟夫 亀谷 浩昌 大城 進

出版者

一般社団法人 日本医療薬学会

雑誌

病院薬学 (ISSN:03899098)

巻号頁・発行日

vol.25, no.3, pp.319-322, 1999-06-10 (Released:2011-08-11)

参考文献数

9

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The drug interaction between sodium valproate (VPA), an anticonvulsant, and faropenem sodium (FRPM), a new penem antibiotic drug, was studied in rats. No significant change was observed in the plasma VPA concentration when compared with the control after the administration of VPA (TOO mg/kg per oral) simultaneously with FRPM (600 mg/kg per oral).

著者

村山 洋子 佐野村 珠奈 篠村 恭久 西林 宏之 安永 祐一 筒井 秀作

出版者

一般社団法人 日本消化器内視鏡学会

雑誌

日本消化器内視鏡学会雑誌 (ISSN:03871207)

巻号頁・発行日

vol.55, no.2, pp.237-249, 2013 (Released:2013-05-21)

参考文献数

30

被引用文献数

1

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胃体部の皺襞肥大は,内視鏡検査や胃X線検査時にしばしば観察される.その大多数はHelicobacter pylori(H. pylori)感染により惹起される皺襞肥大型胃炎である.その特徴は,胃体部粘膜の腺窩上皮の過形成および高度の炎症を認め,胃酸分泌の低下を伴い,皺襞肥大の程度に従って胃癌のリスクが増加し,特に胃体部に未分化型胃癌が増加することである.H. pylori除菌により,これらの所見は改善し,胃体部の皺襞肥大はほぼ正常化し白濁した粘液の付着の消失を認めることで胃癌が発見しやすくなる.皺襞肥大型胃炎は,H. pylori感染者のなかでも胃癌発症のハイリスク群と考えられる.皺襞肥大型胃炎において,H. pyloriの除菌が胃癌発生の予防につながるかどうかは,今後明らかにする必要がある.

著者

小暮 修三 Shuzo Kogure

出版者

東京海洋大学

雑誌

東京海洋大学研究報告 (ISSN:21890951)

巻号頁・発行日

vol.10, pp.6-19, 2014-02-28

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戦前期の写真絵葉書は、現在のような地方の土産物に収まることなく、当時の新聞や雑誌以上に優れた視覚メディアとして機能していた。事実、その解像度は極めて高く、他の如何なる紙媒体よりも高画質の写真を人々に提供していたのである。それはすなわち、絵葉書が、そこに写し込まれた風景や風俗、被写体に対する見る者の意識のあり方を固定化していったことを意味している。このようなメディアの被写体として、海女は頻繁に写され続けていた。絵葉書の〈海女〉は、それを見る者の視覚的経験に対して、どのような影響をもたらしたのか?そして、そのような影響は、時代によって、どのように変遷していったのか?本稿では、公的機関では最多種/数と思われる『甦る戦前の〈海女〉:戦前海女絵葉書集』の分析に基づき、海女の写し出された時代状況や社会状況を踏まえつつ、見る者に対する影響について考察を行ってゆきたい。それは取りも直さず、明治期以降の国民国家化の過程における〈郷土=地方〉の創出から、資本主義の拡大に伴う〈地方〉の観光商品化、そして軍靴の響きを伴う国家主義化に至る時代的・社会的変遷について、海女への〈眼差し〉を通して追ってゆくことでもある。

著者

di Giacomantonio Sonia

出版者

早稲田大学大学院アジア太平洋研究科出版・編集委員会

雑誌

アジア太平洋研究科論集 (ISSN:13466348)

巻号頁・発行日

no.23, pp.133-151, 2012-03

著者

藤原 多見夫 木村 陽登 古井 シゲ子 関谷 宏三 駒村 研三

出版者

広島県果樹試験場

巻号頁・発行日

no.12, pp.29-38, 1987 (Released:2011-03-05)

著者

黒田 基樹

出版者

駿河台大学

雑誌

基盤研究(B)

巻号頁・発行日

2018-04-01

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実績概要今年度における史料蒐集については、白河市小峰城博物館、静岡市徳願寺、藤枝市郷土博物館、藤枝市円領寺、静岡県立中央図書館静岡県歴史文化情報センター、弘前市立図書館、日光市歴史民俗資料館、高岡市立博物館、糸魚川市歴史民俗資料館において調査・撮影し、関係史料を蒐集した。またさくら市ミュージアムで古河公方足利家関係展示の見学を行った。このうち白河市小峰城博物館においては「結城白河文書」の調査を行い、室町期・戦国期の関東に関する史料について熟覧のうえ撮影を行った。その他、静岡市安養寺、御前崎市中山家文書、彦根城博物館所蔵井伊家文書・木俣家文書・三浦家文書について、写真提供をうけた。これらの調査・蒐集により、重要文書の確認、実見を行うことができ、貴重な史料の蒐集と調査を行いえた。刊本史料集の検索については、前年度に引き続いてすすめた。刊本史料集から関係文書を検出し、入力作業をすすめている。研究会についてはコロナ禍のため開催することはできなかった。ただし研究成果の蓄積はすすめており、その成果については、今年度刊行を予定している『古河公方足利成氏・政氏とその時代』『北条氏康とその時代』を編集し、原稿を出版社に入稿済みである。またそこにおいて、足利成氏・政氏の発給文書の総編年化作業についてはほぼ完了するものとなっている。

著者

Naoki Fujimura Hideaki Obara Kentaro Matsubara Susumu Watada Shintaro Shibutani Takurin Akiyoshi Hirohisa Harada Yuko Kitagawa

出版者

The Japanese Circulation Society

雑誌

Circulation Journal (ISSN:13469843)

巻号頁・発行日

vol.80, no.1, pp.118-123, 2015-12-25 (Released:2015-12-25)

参考文献数

43

被引用文献数

17 20

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Background:Clinically distinct differences exist between East Asian and Caucasian subjects, but data for type 2 endoleak (T2EL) are limited in the East Asian population. The aim of this study was to analyze the characteristics of East Asian T2EL using a Japanese multicenter database.Methods and Results:Retrospective analysis of 832 endovascular aneurysm repairs performed from 2008 to 2014 were conducted. T2EL was observed in 234 cases (28.1%), and in 32 cases (3.8%) it led to sac expansion >5 mm caused by isolated T2EL (median follow-up, 35.6 months). On univariate and multivariate analysis, non-smoker status (odds ratio [OR], 2.216; P<0.001), Excluder stent graft (OR, 2.027; P<0.001), and T2EL at final angiogram (OR, 2.080; P<0.001) were risk factors for T2EL. On multivariate analysis for isolated T2EL with sac expansion, only non-smoker status remained (OR, 2.671; P<0.001). Other than T1EL, isolated T2EL was the most significant risk factor for sac expansion (OR, 18.486; P<0.001). Furthermore, out of 11 transarterial embolization procedures initiated, 4 led to rupture during follow-up.Conclusions:East Asian T2EL had a strong relationship with non-smoker status. Also, T2EL was a significant risk factor for sac expansion, which sometimes led to rupture even after intervention. Along with the high prevalence of T2EL observed, East Asian T2EL may not always be benign. (Circ J 2016; 80: 118–123)

著者

伏見 了 野口 悟司 船越 文男 高階 雅紀 中田 精三 田野 保雄

出版者

一般社団法人 日本医療機器学会

雑誌

医科器械学 (ISSN:0385440X)

巻号頁・発行日

vol.70, no.12, pp.648-651, 2000-12-01 (Released:2022-02-17)

参考文献数

8

被引用文献数

10 6

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Detergents contained enzymes that claim stronger washing ability and less damages are used widely for washing out blood or minute tissues adhered to various operation apparatus. It is known that enzyme protein shows maximum activity at 40℃ and is more stable when stored at the lower temperature. However, detergents contained enzymes are stored at room temperature in the most of operation theaters, and furthermore they are transported from manufacturers to any of distribution route in nonrefrigerated condition. When we measured Protease activities at 4℃ and 40℃ during 161 days storage period, the activity at 4℃ was stable but at 40℃ decreased 38.0% in average. In comparison of Protease activities at 20℃ and 40℃, the latter showed twice higher activity. When we studied the correlation between temperatures and the washing ability of detergents contained enzymes using Adenosine triphosphate as the marker, the washing ability at 40℃ was stronger than that at 20℃.

著者

工藤平助 原著

出版者

教育社

巻号頁・発行日

1979

著者

川路 茂保 小笠原 健一

出版者

The Institute of Electrical Engineers of Japan

雑誌

電気学会論文誌D(産業応用部門誌) (ISSN:09136339)

巻号頁・発行日

vol.116, no.4, pp.435-440, 1996-03-20 (Released:2008-12-19)

参考文献数

14

被引用文献数

1 2

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Genetic Algorithms (GAs) are powerful and usable algorithms for the nonlinear optimization problem, and some studies of application of GA to the control problem were reported. The search process of GA depends on the fitness value which is assigned to each candidate solution by the fitness function. But as the control objective is more complicated, the design of the proper fitness function becomes more difficult.In this paper, we propose a new search method of GA which reduces the difficulties of the design of the fitness function. In our method, the control objective is divided into some intermediate objectives according to the control strategy, and the search process of GA proceeds with the fitness function for the intermediate objective. The search process is controlled by switching the fitness function based on the average fitness value of the current candidate solutions so that the optimum solution is found. Thus, the search space is structured by using the fitness function and the structure is changed by switching the fitness function based on the quality of the current candidate solutions. In order to confirm the availability of the proposed method, the swing-up control problem of a pendulum is used as an application example and the simulation results are given.

著者

斉藤 雄次

出版者

日本地域政策学会

雑誌

日本地域政策研究 (ISSN:13485539)

巻号頁・発行日

vol.25, pp.44-51, 2020-09-30 (Released:2022-02-25)

参考文献数

20

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Recently, various mock councils for high school students are held in Japanese municipalities. The purpose of those practice is to encourage high school students to take an interest in politics, and to advance assembly reform by local council. However, mock councils for high school students has a role of deliberation among participants, such as high school students and local council members. Therefore, if opinion and policy suggested by high school students are discussed in local council, its quality as deliberation will be enhanced. As a result, It will lead to the reflection of youth opinions in society.

著者

駒田 致和

出版者

公益財団法人 パブリックヘルスリサーチセンター

雑誌

ストレス科学研究 (ISSN:13419986)

巻号頁・発行日

vol.32, pp.93-95, 2017 (Released:2017-12-27)

著者

小畑 元 黄 国宏

出版者

一般社団法人日本地球化学会

雑誌

地球化学 (ISSN:03864073)

巻号頁・発行日

vol.56, no.3, pp.33-46, 2022-09-25 (Released:2022-09-25)

参考文献数

98

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Trace metals, like iron, copper, zinc and cobalt, in seawater are essential for phytoplankton growth and limit the primary production in some oceanic regions. It is crucial to reveal not only distributions of the metals but also their chemical speciation in seawater because their availability to phytoplankton depends on their speciation. At present, it is well known that more than 99% of iron and copper are complexed with organic ligands in seawater, which was revealed mainly by using voltammetry. In this review, we introduce the electroanalytical methods of organic ligands for trace metals in seawater. Moreover, we indicate the voltammetric methods to determine nanomolar levels of specific organic ligands for trace metals, such as humic substances and thiols, in seawater.

著者

木下 亮平 長城 晃一 石附 智奈美 宮口 英樹

出版者

一般社団法人 日本作業療法士協会

雑誌

作業療法 (ISSN:02894920)

巻号頁・発行日

vol.40, no.1, pp.34-41, 2021-02-15 (Released:2021-02-15)

参考文献数

34

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要旨:地域在住高齢者298名を対象に主観的幸福感(Satisfaction with Life Scale;SWLS)と活動の参加状況(Self-completed Occupational Performance Index;SOPI),基本属性(年齢,性別,慢性疾患,婚姻状況,同居者)の関連性を検討した.SWLSへの関連は,SOPI(β=0.415)と年齢(β=0.187)であった(p<0.05).年齢階級別のSWLSとSOPIの関連性は,前期高齢者群(R=0.477),後期高齢者群(R=0.426)に正の関連を認め(p<0.05),超高齢者群に認めなかった(p>0.05).活動の参加状況が主観的幸福感の充足に寄与しており,作業療法の疫学的根拠を拡大する可能性が示唆されたが,超高齢者群には,主観的幸福感促進の活動参加状況に関する調査課題が示された.

著者

Yohei BAMBA Takanori FUKUNAGA Masao UMEGAKI Yasuaki TSUCHIDA Manabu SASAKI

出版者

The Japan Neurosurgical Society

雑誌

NMC Case Report Journal (ISSN:21884226)

巻号頁・発行日

vol.9, pp.365-369, 2022-12-31 (Released:2022-10-21)

参考文献数

12

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Syringomyelia is often associated with Chiari malformation, trauma, infection, and spinal cord tumor. Although they are relatively rare diseases, arachnoid cysts and its related pathology, "arachnoid web" can sometimes lead to syrinx formation at the thoracic vertebral level. However, syrinx formation caused by degenerative spinal disorders, particularly at the thoracic vertebral levels, has rarely been reported. Herein, we present a case of syringomyelia with thoracic ossified yellow ligament (OYL) in a 79-year-old man, who underwent initial posterior decompression followed by arachnoid web removal. Posterior decompression via laminectomy of thoracic vertebra 2 and removal of the OYL improved the syrinx partially, but dorsal indentation of the spinal cord and a remnant syrinx were observed in post-operative magnetic resonance images, subsequent to the second surgery's successful removal of the arachnoid web, which had dorsally compressed the spinal cord. After the second operation, the syrinx shrunk further, and the patient could walk independently at 5 months after the operations. In our case, both the OYL and arachnoid web were responsible for syrinx formation. Therefore, the coincidence of degenerative vertebral diseases with a syrinx might indicate the coexistence of an underlying lesion. Furthermore, the arachnoid web in this case might have formed due to the denaturation of the arachnoid cyst triggered by the OYL.

著者

Takashi ASAHI Kiyonobu IKEDA Jiro YAMAMOTO Yuko MURO Atsuko MORI Nobutaka YAMAMOTO

出版者

The Japan Neurosurgical Society

雑誌

NMC Case Report Journal (ISSN:21884226)

巻号頁・発行日

vol.9, pp.357-363, 2022-12-31 (Released:2022-10-21)

参考文献数

29

被引用文献数

1

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Cerebral edema around the lead has been reported as a complication of deep brain stimulation; however, the causes remain unknown. Herein, we present a rare case of sudden cerebral edema around the lead occurring after deep brain stimulation. This was accompanied by cerebrospinal fluid (CSF) leakage into the subcutaneous thoracic pocket around the implantable pulse generator in a 53-year-old man with Parkinson's disease. No such case has been reported thus far. Lumbar drainage was performed to improve CSF leakage. The cerebral edema initially responded to steroids, but then it stopped responding to treatment. The edema appeared alternately on the left and right sides, and cyst formation was noted around the left lead. There are some reports of cyst formation around the lead; however, in our case, images were used to monitor the edema and cyst from their appearance to their disappearance. Our data suggest that cyst formation and cerebral edema are related.

著者

堤 邦彦

出版者

日本文学協会

雑誌

日本文学 (ISSN:03869903)

巻号頁・発行日

vol.54, no.10, pp.2-12, 2005-10-10 (Released:2017-08-01)

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女人蛇体といった説話・伝承のモチーフの変遷を、古代アニミズムの伝承や中世の仏教唱導を出発点に追尾しながら、近世文芸のなかに、そうした題材が固定化するまでの展開史を明らかにしたもの。とりわけ中世唱導文芸を苗床とする『法華経』竜女成仏説話型の蛇身譚が、女性の嫉妬や心の奥底の邪念を戒める説話に援用され、さらに江戸の倫理啓蒙思想、女訓文芸とからみながら怪異談の素材に姿を変えるさまを考察する。

著者

Kazuya Nagasawa Kouki Mizuno

出版者

Carcinological Society of Japan

雑誌

Crustacean Research (ISSN:02873478)

巻号頁・発行日

vol.51, pp.31-38, 2022-03-11 (Released:2022-03-11)

参考文献数

18

被引用文献数

1

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An ovigerous female of Argulus matuii Sikama, 1938 was collected from the body surface of a yellowfin seabream Acanthopagrus latus (Houttuyn, 1782) in a cove facing the Bungo Channel off Ehime Prefecture, western Japan. This represents a new host record for A. matuii, and the female collected is herein described. This female, which was fixed and preserved in 70% ethanol, showed a prominent body coloration, i.e., six streaks of yellow fringed with dark brown pigments, on the dorsal surface of the carapace even on 279th day (ca. nine months) after fixation, but the yellow streaks disappeared and the dark brown fringes were fading on 1675th day (ca. four years and seven months) after fixation. Thus, this paper reports on the usefulness of those yellow streaks in identification of A. matuii for a certain period after fixation but also emphasizes the importance of a detailed examination of morphological features in identification of long-term ethanol-preserved argulid specimens. The species is distinguished from the five marine congeners from Japan by its possession of numerous supporting rods in the marginal membranes of the first maxillae.