著者

Yosuke Hata Osamu Iida Shin Okamoto Takayuki Ishihara Kiyonori Nanto Takuya Tsujimura Naoko Higashino Taku Toyoshima Ikurou Kitano Yoshihiko Tsuji Mitsuyoshi Takahara Toshiaki Mano

出版者

Japan Atherosclerosis Society

雑誌

Journal of Atherosclerosis and Thrombosis (ISSN:13403478)

巻号頁・発行日

pp.63773, (Released:2022-08-27)

参考文献数

25

被引用文献数

1

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Aims: This study aimed to investigate the long-term impact of guideline-directed medical therapy (GDMT) on 10-year mortality in patients with chronic limb-threatening ischaemia (CLTI) after revascularization. Methods: We performed a retrospective multicentre study enrolle 459 patients with CLTI who underwent revascularization (396 endovascular therapy [EVT] and 63 bypass surgery [BSX] cases) between January 2007 and December 2011. The primary outcome measure was all-cause mortality. We additionally explored the predictors for all-cause mortality using Cox regression hazard models; the influence of GDMT, defined as prescription of antiplatelet agents, statins, and angiotensin converting enzyme (ACE) inhibitors or angiotensin receptor blockers (ARBs) in aggregate, on all-cause mortality, and the association between baseline characteristics using interaction effects. Results: During the 10-year follow-up after revascularization, 234 patients died. In Kaplan-Meier analysis, 10-year mortality was significantly lower in patients who received statins (p<.001) and ACE inhibitors or ARBs (p=.010) than those who did not. However, there were no differences in 10-year mortality between patients who received anti-platelet agents and those who did not (p=.62). Interaction analysis revealed that GDMT had a significantly different hazard ratio in patients who were and were not on hemodialysis and in those treated with EVT or BSX (p for interaction =.002 and .044, respectively). In the multivariate analysis, age >75 years, non-ambulatory status, hemodialysis, congestive heart failure, left ventricular ejection fraction <50%, and GDMT were significantly associated with all-cause mortality. Conclusions: Appropriate GDMT use was independently associated with 10-year mortality in patients with CLTI after revascularization.

著者

内田信也 著

出版者

実業之日本社

巻号頁・発行日

1951

著者

川村 輝典

出版者

日本新約学会

雑誌

新約学研究 (ISSN:02869055)

巻号頁・発行日

vol.29, pp.37-50, 2001 (Released:2021-09-07)

著者

佐藤 海二

出版者

自動制御連合講演会

雑誌

自動制御連合講演会講演論文集 第52回自動制御連合講演会

巻号頁・発行日

pp.70, 2009 (Released:2010-01-22)

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本論文は,NCTF制御と呼ぶ精密運動システムを簡単に設計・実現する方法とその応用結果について述べている.用いられるコントローラは,動作の規範となり位相面上に描かれるNCTとそれに追従させるためのPI補償器より構成される.NCTは開ループ応答波形から簡単に得られ,補償器の調整も簡単である.制御対象としてボールねじ機構を取り上げ,設計手順,制御性能について説明している.

著者

塚本 博康 倉又 哲夫 柏村 進一郎 水上 直樹 佐藤 吉永 石川 久史 志村 進

出版者

Japanese Society for Mastication Science and Health Promotion

雑誌

日本咀嚼学会雑誌 (ISSN:09178090)

巻号頁・発行日

vol.4, no.1, pp.33-39, 1994-12-25 (Released:2010-07-21)

参考文献数

10

被引用文献数

1

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It is very important to prevent train drivers from falling into drowsiness during train operation. Most of drivers have tried various devices to keep up arousal level such as openig the window, standing up, loud speaking during train operation, but they say that nothing was effective. We have considered that we need to study the problem systematically in seeking for any effective method. We already have established the evaluation method for determination of arousal level synthesizing skin potential level and blinking rate, and compared the effects of gum chewing, listening to music, light physical exercise, etc.This time, we take up the gum chewing as one of the effective devices and prepare a gum with components having both arousal effect and special flavor. To confirm its arousal effect, we compare the effect of this special gum with the gumbase and the marketed gum (BB-gum). A total of 10 subjects, five males and five females, are examined. Three subjects a day are submitted to 30 minutes of gum chewing for evaluation of their arousal levels.Results indicate that the arousal effect of the special gum remains at the highest level for 30 minutes, but the gumbase drops immediately to the lowest level, and that of the BB-gum yields the same effect as the gumbase in 18 minutes of chewing.It has been well known that the arousal effect of gum comes from the movement stimulus of chewing muscles, but it can be said from the results of experiment that components having arousal effect and special flavor in the special gum are more effective in maintaining the arousal level than the movement stimulus of chewing muscles.

著者

山中 大子

出版者

一般社団法人 日本繊維製品消費科学会

雑誌

繊維製品消費科学 (ISSN:00372072)

巻号頁・発行日

vol.47, no.11, pp.640-645, 2006-11-25 (Released:2010-09-30)

参考文献数

11

著者

モギレフスカヤ著 宮川やすえ訳

出版者

偕成社

巻号頁・発行日

1972

著者

高橋 薫 タカハシ カオル Kaoru Takahashi

雑誌

21世紀社会デザイン研究 : Rikkyo journal of social design studies

巻号頁・発行日

vol.10, pp.265-274, 2011

著者

中山 英介

出版者

一般社団法人 溶接学会

雑誌

溶接学会誌 (ISSN:00214787)

巻号頁・発行日

vol.75, no.6, pp.461-465, 2006 (Released:2011-08-01)

参考文献数

4

被引用文献数

3 3

出版者

厚生堂

巻号頁・発行日

1900

著者

平野 太一 田中 文英

出版者

一般社団法人 人工知能学会

雑誌

人工知能学会全国大会論文集 第36回 (2022)

巻号頁・発行日

pp.3Yin209, 2022 (Released:2022-07-11)

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SNSの誹謗中傷の抑制は,つらい思いをする人を減らすために重要である.日本政府は侮辱罪の罰則強化に乗り出しているが,未だ施行日は不透明である.また,注意喚起メッセージを表示する試みがなされている.しかし,誹謗中傷の根本的かつ長期的な抑制には,投稿者自身の意識・行動変容が不可欠だと考える.そこで,快感の源を誹謗中傷から感謝に変える手法を検討する.具体的には,投稿者がポジティブなメッセージを投稿し,相手からポジティブな返信を受け取るのが気持ち良いと実感させるものである.そのために,エージェント(笑顔の投稿者)がネガティブなメッセージに含まれる誹謗中傷ワードをポジティブな言葉に変換する.また,架空の相手からのポジティブな返信メッセージを自動的に生成し,投稿者に向けて通知する.本稿では,初期開発の概要と進捗状況を報告する.

著者

アニーシャ ニシャート 鈎 治雄 Aneesah NISHAAT Haruo MAGARI

出版者

創価大学教育学部・教職大学院

雑誌

教育学論集 (ISSN:03855031)

巻号頁・発行日

no.72, pp.179-193, 2020-03-31

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Concept of happiness has been pursued since the 4 th- 5 th century BC in Greek philosophyand is still widely discussed to the date. Many studies have shown that there were culturaldifferences in the concept of well-being, and the results of those studies have providedinteresting suggestions. Seligman (1991) argued that the use of the concept of happiness in a monistic way, inpositive psychology is problematic. He suggested that using the term “well-being” is moreappropriate. Diener (1984), on the other hand, conducted research on human well-being usingthe concept of subjective well-being, and considered that subjective well-being is a conceptsynonymous with well-being. So this paper examined happiness using the concept of wellbeing,and discussed future research subjects. This paper explores well-being from the viewpoint that people in any country are the samehuman beings. Certainly, there are differences in this world, such as race, religion, culture,income and living environment, and it cannot be denied that these differences createdifferences in the individualʼs view of happiness. On the other hand, every person sharessomething in common while living such as learning, working, and living in a relationship withfamily, friends and others in this world. They encounter common suffering and difficulties suchas illness, economic problems and relationships at home and in the workplace. At the end oflife, they face the common and more fundamental problems of human beings, such as agingand death. If these events are common and universal in their life, the common and universal goals forhuman beings across the borders can be considered happiness and well-being and the ways toachieve them. Considering these points, this paper will focus on well-being from apsychological perspective.

著者

山口 格

出版者

北海道大学教育学部教育方法学研究室

雑誌

教授学の探究 (ISSN:02883511)

巻号頁・発行日

vol.6, pp.5-15, 1988-03-30

著者

末松謙澄 著

出版者

東京文学社

巻号頁・発行日

1887

著者

小泉 潤 泉 主馬 大家 利之

出版者

一般社団法人日本体力医学会

雑誌

体力科学 (ISSN:0039906X)

巻号頁・発行日

vol.71, no.4, pp.355-365, 2022-08-01 (Released:2022-07-12)

参考文献数

32

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It has been suggested that inspiratory muscles fatigue impairing blood flow to the active limb muscle via respiratory muscle metaboreflex. The purpose of this study was to investigate the effects of inspiratory muscle fatigue on exercise performance and muscle tissue oxygenation in high-intensity exercise takes about 3.5~5min. Eleven healthy males subjects performed two conditions of constant-load exercise to exhaustion (TTE) on a cycle ergometer at 100% of maximal oxygen uptake. The two conditions—inspiratory muscle fatiguing (IMF) and non-fatiguing (PLA) —which had different intensity inspiratory resistance breathing (IRB) were performed before exercise. Muscle tissue oxygenations were measured by deoxyhemogrobin (HHb), oxygen saturation index (StO2) from right vastus lateralis during TTE. All data were analyzed from nine subjects whose inspiratory muscle were fatigued by IRB in IMF. Results: TTE was significantly shorter in IMF compare to PLA (244±31s vs. 268±38s, p<0.05). HHb was significantly higher and StO2 was significantly lower in IMF than in PLA (p<0.05). Conclusion: High-intensity exercise completed in 3.5~5 minutes, it was suggested that inspiratory muscle fatigue reduced the oxygen deriver to active limb muscle, resulting in decrease exercise performance. Improving function of inspiratory muscles, such as in inspiratory muscle training, may improve oxygenation of the active limb muscle and enhance exercise performance.

著者

音楽之友社編

出版者

音楽之友社

巻号頁・発行日

2012

著者

武林無想庵著

出版者

記録文化社

巻号頁・発行日

1985

著者

山本夏彦著

出版者

文芸春秋

巻号頁・発行日

1989

著者

川見典久 石谷慎編

出版者

黒川古文化研究所

巻号頁・発行日

2018