著者
Kunihito Matsumoto Toshihiko Amemiya Motohiro Ito Yusuke Hayashi Kenichiro Watanabe Ko Dezawa Yoshinori Arai Kazuya Honda
出版者
Nihon University School of Dentistry
雑誌
Journal of Oral Science (ISSN:13434934)
巻号頁・発行日
vol.62, no.1, pp.62-66, 2020 (Released:2020-01-29)
参考文献数
35
被引用文献数
2

This study was performed to develop a new rat model of reduced masticatory activity in order to assess the effect of this reduction on the morphology of the temporomandibular joint (TMJ) over time. Female rats were used, and ovariectomy was performed to simulate aged/postmenopausal status. Twenty-four SD rats aged 6 weeks were divided into four groups: ovariectomy/sham procedure (Ov/S); ovariectomy/reduced masticatory activity (Ov/RMA); non-Ov/S (NO/S); and non-Ov/RMA (NO/RMA). The RMA procedure involved grinding down the edges of the upper and mandibular incisors by about 3 mm and supplying the rats with a powdered diet. The bilateral TMJ was examined by micro-computed tomography at 0, 1, 2, 4, 6, and 8 weeks after the start of RMA. Condylar width was greater in the NO/S group than in the Ov/S group after the 2nd week, showing that ovariectomy reduced the width of the condyle. After the 2nd week, significant differences in condylar width were apparent between the NO/S and NO/RMA groups, and between the Ov/S and Ov/RMA groups. This RMA procedure appeared to provide a good model of reduced masticatory activity. The present findings in female rats suggest that reduction of appropriate mastication activity in the growth period results in poor growth of the mandibular condyle and immediately induces atrophy of the mandibular condyle under conditions simulating aged/postmenopausal status.
著者
Yasuhiro Namura Toshiki Takamizawa Yasuki Uchida Mizuki Inaba Daichi Noma Tomoko Takemoto Masashi Miyazaki Mitsuru Motoyoshi
出版者
Nihon University School of Dentistry
雑誌
Journal of Oral Science (ISSN:13434934)
巻号頁・発行日
vol.62, no.1, pp.48-51, 2020 (Released:2020-01-29)
参考文献数
20
被引用文献数
8

Although there have been improvements in bracket systems precoated with adhesive, removal of adhesive remnants continues to be problematic. This study compared the hardness and maintainability of precoated adhesive with other commercial adhesives. Knoop hardness values were measured after light- or chemical-induced initial curing, immersion in distilled water at 37°C for 24 h and 1,000 and 10,000 thermal cycles after 24 h. Additionally, the forces required to move brackets by 0.5 mm were measured during bracket positioning, and brackets bonded to bovine enamel were examined by field-emission scanning electron microscopy. The Knoop hardness values of the precoated adhesives were lower than those of commercial resin composite adhesives, and hardness was dependent on the amount of filler in the resin matrix. The ability to maintain the device position may depend on the resin matrix composition. Precoated adhesives with less filler and more matrix material are light curable, and remnant resin may be easily removed.
著者
Sayaka Maruyama Hirofumi Tsutsumi Hikaru Izawa Toshinobu Komuro
出版者
Nihon University School of Dentistry
雑誌
Journal of Oral Science (ISSN:13434934)
巻号頁・発行日
vol.62, no.1, pp.28-31, 2020 (Released:2020-01-29)
参考文献数
11
被引用文献数
4

This study attempted to determine the minimum number of cells required to conduct DNA analyses effectively. Oral mucosal cells obtained from eight persons were suspended and individually collected by using micromanipulation technique. DNA was extracted and amplified by whole-genome amplification (WGA). Nuclear DNA was extracted to evaluate the feasibility of autosomal short tandem repeat (STR) polymorphism and Y-chromosomal STR polymorphism analyses. Tests were conducted with 20 and 30 cells, to determine the minimum number of cells required for each DNA analysis. Tests with 20 cells were repeated 5 times, to examine reproducibility. When five or 10 cells were used, loci could not be identified for most alleles. Furthermore, DNA polymorphism analyses of a single cell transferred directly to a polymerase chain reaction solution were unsuccessful. The present findings suggest that, in forensic identification, 20 or more cells are required in order to obtain clear results from autosomal and Y-chromosomal STR polymorphism analyses. Furthermore, the feasibility of sample preservation and reexamination was also confirmed by DNA amplification with WGA.
著者
Hidetaka Tsuzuki Yoko Inamoto Eiichi Saitoh Keiko Aihara Seiko Shibata Hitoshi Kagaya Keiko Onogi Enri Nakayama Mitsuyasu Sato Koichiro Ueda
出版者
Nihon University School of Dentistry
雑誌
Journal of Oral Science (ISSN:13434934)
巻号頁・発行日
vol.62, no.1, pp.18-22, 2020 (Released:2020-01-29)
参考文献数
19
被引用文献数
7

This study used 320-row area detector computed tomography (320-ADCT) to determine whether kinematic swallowing events and bolus movement through the oropharynx are affected by bolus consistency and angle of recline. Fourteen healthy adults (4 men, 10 women; age, 22-90 years) underwent 320-ADCT assessment during three 10-mL barium swallow tests, with honey-thick liquid at 60° recline (60°thick), thin liquid at 60° recline (60°thin), and thin liquid at 45° recline (45°thin). The times of swallowing events were measured and compared among the different tests. Bolus propulsion, onset time of true vocal cord (TVC) closure, and upper esophageal sphincter opening were significantly earlier for 60°thin than for 60°thick. Onset time did not significantly differ between 60°thin and 45°thin; however, greater variability was noted for onset of TVC closure with 45°thin, as the TVC started to close before onset of swallowing in 30% of participants. Modulation of TVC closure depends on bolus transport in different reclining positions. The 45° reclining position elicited pre-swallow TVC closure in some participants, which suggests that excessive recline can increase perceived risk of airway invasion during swallowing.
著者
Jui Yen Chen Asako Kubo Masamichi Shinoda Akiko Okada-Ogawa Yoshiki Imamura Koichi Iwata
出版者
Nihon University School of Dentistry
雑誌
Journal of Oral Science (ISSN:13434934)
巻号頁・発行日
vol.62, no.1, pp.13-17, 2020 (Released:2020-01-29)
参考文献数
22
被引用文献数
7

Although xerostomia can cause persistent oral pain, the mechanisms underlying such pain are not well understood. To evaluate whether a phosphorylated p38 (pp38)-TRPV4 mechanism in trigeminal ganglion (TG) neurons has a role in mechanical hyperalgesia of dry tongue, a rat model of dry tongue was used to study the nocifensive reflex and pp38 and TRPV4 expression in TG neurons. The head-withdrawal reflex threshold for mechanical stimulation of the tongue was significantly lower in dry-tongue rats than in sham rats. The numbers of TRPV4- and pp38-immunoreactive cells in the TG were significantly higher in dry-tongue rats than in sham rats. Many TRPV4-IR cells were also pp38-immunoreactive. The number of TRPV1-IR cells was unchanged in the TG after induction of tongue dryness. Local injection of a TRPV4 blocker attenuated tongue mechanical hypersensitivity in dry-tongue rats. Intraganglionic injection of a selective p38 MAP kinase inhibitor eliminated tongue hypersensitivity in dry-tongue rats and suppressed TRPV4 expression in TG neurons. The present findings suggest that TRPV4 activation via p38 phosphorylation in TG neurons is involved in mechanical hypersensitivity associated with dry tongue. These mechanisms may have a role in pain associated with xerostomia.
著者
有井 彩 山根 精一郎
出版者
日本雑草学会
雑誌
雑草研究 (ISSN:0372798X)
巻号頁・発行日
vol.51, no.4, pp.263-268, 2006-12-22
被引用文献数
1
著者
服部 克也
出版者
東京水産大学
巻号頁・発行日
2003

東京水産大学博士学位論文 平成15年度(2003) 論文博士 乙第83号
著者
山本 和子 緒方 昭 中森 靖郎 浅野 長一郎 畠中 駿逸
出版者
The Japanese Society for Hygiene
雑誌
日本衛生学雑誌 (ISSN:00215082)
巻号頁・発行日
vol.28, no.4, pp.416-424, 1973-10-30 (Released:2009-02-17)
参考文献数
12

The purpose of this paper is to make clear a comprehensive relationship between two groups of measurements of blood pressure and physical constitution. The first group of measurements include pulse rate, systolic blood pressure and diastolic blood pressure, and the second group of measurements include height, weight, chest circumference, circumference of the upper arm and sitting height.These figures are taken from the Nutrition Survey of Japanese, including 6617 males and 8909 females, investigated in May, 1961.Appling the canonical correlation analysis, we found the following results.1) Only two canonical correlations were statistically significant.2) The value of the first canonical correlation was 0.262 for males and 0.381 for females. The corresponding canonical variables were considered as a blood pressure factor and a physical type factor, respectively.3) It seemed that, as the physical type factor changed with age, the blood pressure factor also changed proportionately.4) The value of the second canonical correlation was rather small but significant, 0.094 for males and 0.108 for females. The corresponding canonical variables seemed to be a pulse-pressure factor and a second physical type factor related to weight (positive) and chest circumference (negative).5) In addition, it was also found that the pulse rate has little to do with the physical type.
著者
木原 直哉
雑誌
情報処理
巻号頁・発行日
vol.61, no.2, pp.136-137, 2020-01-15
著者
稗島 武
出版者
The Japan Sociological Society
雑誌
社会学評論 (ISSN:00215414)
巻号頁・発行日
vol.56, no.1, pp.200-213, 2005-06-30 (Released:2010-04-23)
参考文献数
15
被引用文献数
2 2

本稿で, 私はレディメイドという衣服のあり方と身体の関係を切り口に, 近代の身体観の変容について論じる.具体的な分析対象としては, 雑誌『アンアン』の記事を用いる.オーダーメイドとレディメイドの大きな違いは, 衣服を着る側から関わることのできない「サイズ規格」に基づいた生産システムにある.このシステムの変化は, 生産の効率化や生産アイテムの多様性を実現した.一方, 体型に関しては, 個別の体型を包摂するとされる「サイズ規格」により作られるがゆえに, 実際の身体と衣服とが適合しない可能性を持つことになってしまった.ここにおいて, レディメイドは, 個別具体的な身体から切り離された「もう1つの身体」を体現するものとなる.この「もう1つの身体」は, 個別具体的な身体を, 1つのラインに順序立て秩序づけるような, メタ次元に存在する「身体」であるといえる.これにより, 人々は, 常にこの「もう1つの身体」に基づいて, 自分の身体を意識せざるをえない.オーダーメイドにおいて, 個別的な対象であった身体は, レディメイドにおいて, 1つのラインに順序立てられ, 秩序づけられていく.自らの身体のみならず, あらゆる身体を包摂すると考えられるメタ次元の「もう1つの身体」の成立.これこそが, レディメイドによってもたらされた身体認識の変化であった.
著者
小根森 元 川西 昌弘
出版者
一般社団法人 日本透析医学会
雑誌
日本透析医学会雑誌 (ISSN:13403451)
巻号頁・発行日
vol.53, no.1, pp.15-20, 2020 (Released:2020-01-28)
参考文献数
14

2018年12月の日本透析医学会統計調査委員会の報告によると, 新規透析導入患者数は2015年以降増加傾向となったと報告された. 導入患者の増加には, 人口高齢化の影響が大きい. そこで透析原疾患の経年的推移と高齢者 (80歳以上) の導入時原疾患の特徴を明らかにするため, 過去7年間の日本透析医学会の統計調査 (CD-ROM版) のデータを用い, 年齢3区分別に原疾患別導入患者数の検討を行った. その結果, 20歳から80歳未満の原疾患割合と罹病率 (透析導入率) は, 糖尿病性腎症, 慢性糸球体腎炎で減少, 腎硬化症, 不明は増加し, その他は横ばいであった. そして, 導入患者の増加は80歳以上の患者数の増加によるものであった. この患者数の増加は高齢者人口の増加が主因であり, 80歳以上の罹病率を増加させている原疾患も関与していると考えられた. 今後は, 高齢者への対策が, 罹病率 (透析導入率) を減らすためにさらに重要になると思われる.

1 0 0 0 OA 官報

著者
大蔵省印刷局 [編]
出版者
日本マイクロ写真
巻号頁・発行日
vol.1888年07月31日, 1888-07-31