出版者
日経BP社
雑誌
日経コンピュータ = Nikkei computer (ISSN:02854619)
巻号頁・発行日
no.922, pp.88-90, 2016-09-29

印刷通販会社のグラフィック(京都市)は7月1日に情報流出の懸念を認知した。中国籍のサーバーから不正アクセスがあったという。顧客の住所・氏名・メールアドレスなど8985件が流出した可能性がある。
著者
高良 恒史 大西 憲明 堀部 紗世 橋詰 勉 金澤 治男 横山 照由
出版者
一般社団法人日本医療薬学会
雑誌
医療薬学 (ISSN:1346342X)
巻号頁・発行日
vol.29, no.1, pp.77-82, 2003-02-10 (Released:2011-03-04)
参考文献数
12
被引用文献数
3 3

For the development of a practical training system to effectively teach sterilization techniques, we conducted on unregistered questionnaire survey of the undergraduate student's view about the training practice for glass ample cutting, and then evaluated and discussed the introduction to practical training of pharmaceutical health care and sciences for the third-grade undergraduate students. Among 96 third-grade undergraduate students, 54 students (56%) had some experience in cutting glass amples while the remaining students did not. Twenty-six of the 54 students with some experience (48%) had some anxiety regarding glass ample cutting, while only 13 of the 42 inexperienced students (31 %) had such anxiety. Twelve of the 13 inexperienced students overcame some anxiety against glass ample cutting. Moreover, 87 of 96 students (91%) considered that receiving practice in glass ample cutting was necessary for them. Consequently, the training programs on glass ample cutting were found to be appropriate and useful for students to develop sufficient practical skills and accurate ability in sterilization techniques. As a result, we are now preparing to introduce a training program for glass ample cutting in addition to the regular practical training of pharmaceutical health care and sciences at Kyoto Pharmaceutical University.
著者
重松 誠 菅 純子 西田 嘉英 澤井 英子 小川 雅史 中川 文夫
出版者
一般社団法人日本医療薬学会
雑誌
医療薬学 (ISSN:1346342X)
巻号頁・発行日
vol.29, no.1, pp.56-61, 2003-02-10 (Released:2011-03-04)
参考文献数
26
被引用文献数
2 2

Cancer chemotherapy and radiation therapy-induced stomatitis often involves symptoms severe enough that the oral ingestion of food may become difficult. We therefore prepared a polaprezinc (zinc N- (3-aminopropionyl) -L-histidine) suspension dispersed in sodium alginate solution (P-AG) as a specific treatment and agent for the prophylaxis of severe stomatitis, and examined the chemical and physico-chemical stability of P-AG for clinical use.The chemical and physico-chemical stability of P-AG was established from its appearance, the percentage polaprezinc content and viscosity immediately after steam sterilization and uniformity after being left to stand for14 days at 25 and 5°C. Similarly, these parameters were examined in photostability testing (40°C, 2000lux) for14 days at the same time. As a result, a change in appearance was observed after steam sterilization according to photostability testing. However, the percentage of polaprezinc contents did not decline after either steam sterilization, photostability testing or after being left to stand for 14 days regardless of the storage temperature. On the other hand, the viscosity of P-AG declined after steam sterilization according to the findings of photostability testing.
著者
武隈 洋 志賀 弘康 山下 恭範 須田 範行 岩井 美和子 岸野 吏志 宮崎 勝巳
出版者
一般社団法人日本医療薬学会
雑誌
医療薬学 (ISSN:1346342X)
巻号頁・発行日
vol.29, no.1, pp.62-65, 2003-02-10 (Released:2011-03-04)
参考文献数
8
被引用文献数
2 2

A 0.625% povidone-iodine solution (PVP-I) for eye washing, a pharmaceutical product prepared in our hospital, is used to disinfect the conjunctival sac in eye surgery. Since iodine is unstable, its bactericidal activity is reduced when PVP-I is diluted. Therefore, the stability of a 0.625% PVP-I solution under various preservation conditions was studied. Its stability was evaluated by pH variation, visual inspection and the residual rate of available iodine. The 0.625% PVP-I solution was stored for 5 weeks at room temperature (25°C) and at 4°C under diffused light or in a dark place. The amount of available iodine was determined by the oxidationreduction titration method according to the fourteenth revised edition of the Japanese Pharmacopoeia (JPXIV). No apparent changes were found by pH variation or visual inspection after storage for 5 weeks either at 4°C or 25°C. The residual rates of available iodine after 5 weeks of storage were 91 % at 25°C and 98% at 4°C, thus suggesting that a reduction in available iodine is smaller at 4°C than at 25°C. This finding also suggests that a reduction in available iodine is dependent on temperature.The results of this study indicate that a 0.625% PVP-I solution for eye washing remains stable for 5 weeks if stored at a temperature of less than 4°C.
著者
有田 悦子 坂本 満夫 恩地 ゆかり 小俣 栄 圓藤 孝子 近藤 芳子
出版者
一般社団法人日本医療薬学会
雑誌
医療薬学 (ISSN:1346342X)
巻号頁・発行日
vol.29, no.1, pp.47-55, 2003-02-10 (Released:2011-03-04)
参考文献数
9
被引用文献数
5 5

During our efforts to develop a training program for new pharmacists, we have come to the opinion that it is essential to understand the personality characteristics of each individual pharmacist. The present study was undertaken to examine the effects of various personality characteristics of new pharmacists regarding their work by psychological tests with existing education programs. The ultimate goal of obtaining basic data would be useful for devising effective training plans for new pharmacists. The subjects consisted of 16 new pharmacists who participated in the training program for new pharmacists conducted at the Q Pharmacy in April through June of 2001. A psychology test, the Tokyo University Egogram (TEG), was administered at the beginning and at the end of training, and the State-Trait Anxiety Inventory (STAI) was administered at the beginning and at the end of training and once a month for two months.An analysis of changes in egograms taken both before and after the training suggested that the effects of the training were manifested in their personality even after a short period of training.Some personality characteristics that seem desirable for pharmacists were derived from the data obtained for pharmacists with highly appraised performances. These include moderately high Critical Parent (CP) and Free Child (FC), high Nurturing Parent (NP) and Adult (A), and moderately low Adapted Child (AC). It is possible that more effective training can thus be provided if not only the trainee but also the trainer understands one's own personality haracteristics.
出版者
日経BP社
雑誌
日経ニューメディア (ISSN:02885026)
巻号頁・発行日
no.1474, pp.11-12, 2015-07-20

改正放送法の下、2015年4月からNHKのネット活用の範囲が拡大した。もちろん、予算の縛りもあることから、費用と効果のバランスを図り続けていくべきことに変わりはない。最小限の話ではあるが、ハイブリッドキャストについては、総務大臣の特任で行われてきた…
著者
平川 雅章 立石 真理 牧野 和隆 千堂 年昭 伊藤 善規 大石 了三
出版者
一般社団法人日本医療薬学会
雑誌
医療薬学 (ISSN:1346342X)
巻号頁・発行日
vol.29, no.1, pp.20-27, 2003-02-10 (Released:2011-03-04)
参考文献数
10

Although the standards for the quality of rubber closures on injectable glass vials were specified in USP 24 in the U.S. and BP 2001 in the U.K., no such guidelines for quality control exist in Japan. In the present study, we investigated the quality of rubber closures on glass vials of frequently-used anti-biotic and anti-viral injections in our hospital, according to the quality control method of rubber closures for aqueous infusion that was standardized in JP14. Sufficiently washed rubber closures were immersed in distilled water, and test solutions were prepared after gently shaking them for 5 min or heating them at 121°C under high-pressure steam for 60 min. The optic transmittance in the resultant solutions was measured at 430nm and 650nm, and the findings were compared with those for the standard values in JP14 for rubber closures on aqueous infusions. Of 23 different rubber closures tested, only one showed a lower transmittance at 430nm when the solution was prepared by gentle shaking. Under the condition of heating with high-pressure steam, 15 products did not reach the criteria at both wavelengths, 3 did not meet the standards set at either of the wavelengths, but 5 had no qualitative problems. We also checked the materials stuffed in 0. 45μm membranes after filtration with an injection by microscopic observations using scanning electron microscopy and by an element analysis with an X-ray energy dispersive microanalyzer. A number of micro-particles were observed and they were found to be composed of silicon, aluminium and titanium.These results indicate that the quality of rubber closures of injectable glass vials varies among products. Therefore, the standards and guidelines for the quality control of rubber closures of injectable glass vials should be established in JP.
著者
三浦 梢 大谷 聡子 鈴木 淳司 海原 康孝 光畑 智恵子 小西 有希子 河村 誠 香西 克之
出版者
一般財団法人 日本小児歯科学会
雑誌
小児歯科学雑誌 (ISSN:05831199)
巻号頁・発行日
vol.49, no.1, pp.11-19, 2011-03-25
参考文献数
17

近年,小児の歯肉のメラニン色素沈着は受動喫煙が関係しているとの報告が多くある。しかし受動喫煙環境下にない小児の歯肉にもメラニン色素がみられることがあり,これについて検討を行った報告はあまりない。そこで,小児の歯肉のメラニン色素沈着の要因となる可能性のある項目ついて研究した。3~11 歳の日本人小児50 名を対象に,歯肉のメラニン色素沈着を,沈着濃さと沈着範囲の2 項目で判定した。沈着濃さは「ない」「極めて薄い」「薄い」「濃い」の4 段階で,沈着範囲はHedin の分類を参考に「0」色素沈着を認めない,「1」1~2 箇所の独立した沈着を認める,「2」3 箇所以上の独立した沈着を認める,「3」色素沈着が帯状をなし左右で独立している,「4」色素沈着が帯状をなし左右で連続している,の5 段階で評価した。調査項目は口呼吸,上顎前歯部歯肉の腫脹,笑った時の上顎歯肉の露出,皮膚の色,日焼け,頭髪の色,唾液中のコチニン濃度,同居者の喫煙状況(同居者の現在および過去における喫煙,喫煙年数あるいは禁煙後の経過年数,喫煙場所,タバコの銘柄,日平均の喫煙本数,同居者以外からの受動喫煙の可能性),偏食,年齢である。これらの項目とメラニン色素沈着との関係を統計学的に分析した結果,「沈着濃さ」に対し日焼け,喫煙者との同居年数,頭髪の色,口呼吸,年齢が,「沈着範囲」に対し日焼け,喫煙者との同居年数,頭髪の色がそれぞれ正に相関した。
著者
降籏 達生
出版者
日経BP社
雑誌
日経コンストラクション (ISSN:09153470)
巻号頁・発行日
no.388, pp.80-83, 2005-11-25

同じ建設会社に勤務し,勉強熱心なB君と,原価についてあまり詳しくないA君とが,予算に関して立ち話をしている。今回は,なぜ予算が必要なのか,そしてどのようにして予算を作成すればよいのかを考えてみよう。夢を実現するために作成する もう少し,A君とB君のやりとりに付き合っていただきたい。 B君「A君の『本当に欲しいもの』って何?」。 A君「そうだなあ。
著者
亀山 多美子
出版者
農林省蠶絲試驗場
巻号頁・発行日
no.111, pp.169-182, 1979 (Released:2011-03-05)
著者
寺山 宏 折井 弘武
出版者
The Japanese Cancer Association
雑誌
GANN Japanese Journal of Cancer Research (ISSN:0016450X)
巻号頁・発行日
vol.54, no.4, pp.455-464_1, 1963-12-31 (Released:2008-10-23)
参考文献数
8

Following previous experiments on the dye-protein binding in in vitro system, the dye-protein binding in in vivo systems is reported, in which 4-dimethylaminoazobenzene amine-N-oxide was administered intragastrically or intramuscularly to rats, mice, and guinea pigs. The binding took place at the site of injection as well as in the liver in the case of intramuscular administration. Amount of the protein-bound dye increased with the dose. LD50 values of 4-dimethylaminoazobenzene amine-N-oxide were compared with that of 4-dimethylaminoazobenzene, using rats and mice, both by intragastric and intraperitoneal administration. The highest toxicity was observed in the intraperitoneal injection of 4-dimethylaminoazobenzene amine-N-oxide. The toxicity decreased to 1/5 (mice) and to 1/15 (rats) in the case of intragastric injection. Addition of 4-dimethylaminoazobenzene amine-N-oxide in the drinking water (0.03%) to rats and mice caused malignant hepatomas in rats, but only adenomatous growth in mouse liver.
著者
林清 五郎 植木 寛 植木 洋子
出版者
The Japanese Cancer Association
雑誌
GANN Japanese Journal of Cancer Research (ISSN:0016450X)
巻号頁・発行日
vol.54, no.4, pp.381-390, 1963-12-31 (Released:2008-10-23)
参考文献数
14

The antitumor activities of 4, 5-bis(ethyleneimino)-1, 2-benzoquinone (OBE), 2, 5-bis(ethyleneimino)-1, 4-benzoquinone (PBE), and 4-ethyleneimino-1, 2-naphthoquinone (NQE) were investigated in Ehrlich carcinoma. OBE was effective not only in prolonging the life-span of mice bearing Ehrlich ascites carcinoma but also in retarding the growth of the solid form of the same tumor. This compound was proved to be effective even in a smaller dose than the minimum effective dose of PBE, with lower toxicity than the latter. With NQE, the mice bearing the same ascites tumor did not survive longer than the control.Ratio of the number of neutrophils to lymphocytes (N/L) in the peripheral blood was compared with the non-treated and the treated groups of animal bearing the tumor. Generally speaking, the more progressed the growth of the ascites tumor was, the greater the value of N/L, but such increase of N/L was eventually observed in case of leucopenia induced by these agents. It may therefore be said that the observation of change of N/L should be considered as an element for evaluation of the result of screening experiment.
著者
遠藤 英也 久米 文弘
出版者
The Japanese Cancer Association
雑誌
GANN Japanese Journal of Cancer Research (ISSN:0016450X)
巻号頁・発行日
vol.54, no.4, pp.443-453, 1963-12-31 (Released:2008-10-23)
参考文献数
23
被引用文献数
2

From the fact that 4-hydroxyaminoquinoline 1-oxide (4-HAQO) as well as 4-nitroquinoline 1-oxide (4-NQO) have λ-phage inducing ability in lysogenic Escherichia coli K12 and from the studies of Okabayashi, showing that not only 4-NQO but also 4-HAQO are mutagenic and able to produce the phenotypically same mutants in Aspergillus niger, similarity between these two substances in their biological actions was examined on (1) carcinogenicity, (2) growth-inhibiting action, and (3) intranuclear inclusion-forming action.1) 4-HAQO•HCl in peanut oil and cholesterol mixture was injected into the subcutaneous tissue of rats. Subcutaneous tumors were induced in 8 of the 15 effective rats (53%) in the first group and in 16 of 17 rats (94%) in the second group.2) Three groups, consisting of 10 mice each, were inoculated with Ehrlich ascites tumor cells intraperitoneally. Twenty-four hours after the inoculation, the first group was treated daily with 0.5mg/kg body weight of 4-HAQO•HCl dissolved in physiological saline containing 0.4% carboxymethylcellulose, the second group with 7mg of 4-NQO, and the third with solvent alone. The treatment was continued for 10 days. All the mice of the first group and all but 2 mice of the second survived over 50 days, whereas the third (control) group survived only 15 days.3) When the Chang's liver cells were incubated for 24 hours at 37° in a culture media containing 4-HAQO•HCl in the final concentration of 7×10-5M, intranuclear inclusions phenotypically identical with those induced by 4-NQO were produced in about 60% of all the cells.These results were discussed in relation to the carcinogenic mechanism of 4-NQO.
著者
平木 潔 入野 昭三 三好 勇夫
出版者
The Japanese Cancer Association
雑誌
GANN Japanese Journal of Cancer Research (ISSN:0016450X)
巻号頁・発行日
vol.54, no.4, pp.427-432, 1963-12-31 (Released:2008-10-23)
参考文献数
13

Five of eight inbred Swiss mice given repeated injections of a small amount of benzene in olive oil developed subcutaneous sarcomas. One of the three tumors transplanted grew and is now maintained as transplants. Morphology of these tumors and histological changes in other organs are described. The present results indicate that benzene is capable of inducing solid malignant tumors in mice. No leukemia or lymphoma was observed among these experimental mice.
著者
藤野 陽平
出版者
三田哲學會
雑誌
哲学 (ISSN:05632099)
巻号頁・発行日
vol.119, pp.295-336, 2008-03

第2部 民俗宗教から観光研究まで投稿論文1. はじめに 台湾のキリスト教の略史と問題設定 (1) 日本における台湾のキリスト教研究とその問題点 (2) 台湾におけるキリスト教研究とその問題の所在 (3) 対象の選出と記述の方法 (4) 台湾における言語 (5) 台湾における宗教内のキリスト教の位置づけ2. 台湾基督長老教会(THE PRESBYTERIAN CHURCH IN TAIWAN) (1) 南部長老教会 (2) 北部長老教会 (3) その後の長老教会の歴史と政治的スタンス3. 台湾聖教会(荷里寧斯,ホーリネス,TAIWAN HOLINESS CHURCH)4. 真耶蘇教会(真イエス教会,True Jesus Church)5. 召会(教会集会所,小群,LITTLE FLOCK,地元にあって合一である立場に立つ教会)6. 分析8. おわりにA study of Christianity that is understood not only from doctrine or theory but also from a social context is needed today. Many studies are being conducted from this point of view as part of a project carried out by the Japanese Association for the Study of Religion and Society. However, most of these studies pertain to Japanese or Korean Christianity. From the East Asian study perspective, there is presently a need for studies on the Chinese people. Therefore, I take Christianity in Taiwan as an example. In 2005, there were some 903,451 Christians in Taiwan. Christianity is secondary to Daoism (about 7,600,000) and Buddhism (about 5,486,000). As of 2007, the population of Taiwan is 22,900,000; therefore, the percentage of Christianity is approximately 4%. The churches that have over 10,000 members are The Presbyterian Church in Taiwan (台灣基督長老教會222,381), Little Flock (召會99,374), True Jesus Church (真耶〓教会70,618), Bread of Life Christian Church in Taipei (台北靈糧堂33,132), Chinese Baptist Convention (中華基督教浸信會聯會26,205), Taiwan Lutheran Church (台灣信義會13,732), and Taiwan Holiness Church (台灣聖教會11,582). So I analyze Christianity in Taiwan, using the Presbyterian Church in Taiwan, Taiwan Holiness Church, True Jesus Church, and Little Flock as examples. I present Christianity for a conclusion that is being constructed in a relation between Taiwanese folk religion and Christianity under the trend of globalization. Moreover, I present a new perspective on the study of religion in Taiwan.
著者
森 和雄
出版者
The Japanese Cancer Association
雑誌
GANN Japanese Journal of Cancer Research (ISSN:0016450X)
巻号頁・発行日
vol.54, no.4, pp.415-425_3, 1963-12-31 (Released:2008-10-23)
参考文献数
17

Cancers of the lung were induced by the repeated subcutaneous injections of 4-nitroquinoline 1-oxide in three groups of rats receiving a total amount of 15, 11, and 7.25mg, respectively. The lung cancer was found in 16 (37.2%) out of 43 effective rats that survived more than 223 days. These cancers were usually adenocarcinomas (30.2%), but there were also some epidermoid carcinomas (7.0%). Both adenocarcinoma and epidermoid carcinoma gave rise to metastases in distant organs. Almost all the rats had multicentric pulmonary adenomas. Various degrees of hyperplasia and metaplasia of bronchial epithelia or alveoli were also observed. Subcutaneous sarcomas often arose in the area of application of the carcinogen. A transplantable strain of the epidermoid carcinoma was separated successfully.
著者
北見 由奈 森 和代
出版者
公益財団法人 パブリックヘルスリサーチセンター
雑誌
ストレス科学研究 (ISSN:13419986)
巻号頁・発行日
vol.25, pp.37-45, 2010
被引用文献数
2

The purpose of this study was to examine the relationship between job search stressors, mental health and social skills in Japanese university students. The subjects were 448 Japanese university students (171 males, 277 females). The questionnaire contained demographics, the state of job hunting, the 12-item General Health Questionnaire Japanese version (Nakagawa & Daibo, 1985), the Job Search Stressor Scale (Kitami, 2009), and the 18-item Kikuchi's Social Skills Scale (Kikuchi, 1988). 1) Analysis by t-test revealed a significant difference in the job search stressors between groups with high and low social skills. 2) The result of regression analysis revealed that low social skills showed higher job search stressors and stronger influence of job search stressors on mental health. These results suggest to reduce job search stressors and to promote mental health by improve the social skills.<br>