著者

長沼 孝雄 中村 洋子 三上 昌子 高橋 俊英 松本 一仁 柿崎 寛 三國 恒靖

出版者

特定非営利活動法人日本臨床細胞学会

雑誌

日本臨床細胞学会雑誌 (ISSN:03871193)

巻号頁・発行日

vol.33, no.5, 1994-09

著者

Makito Oku

出版者

Information Processing Society of Japan

雑誌

IPSJ Transactions on Bioinformatics (ISSN:18826679)

巻号頁・発行日

vol.12, pp.9-16, 2019 (Released:2019-03-25)

参考文献数

16

被引用文献数

3

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In this paper, I propose two novel methods for extracting synchronously fluctuated genes (SFGs) from a transcriptome data. Variability and synchrony in biological signals are generally considered to be associated with the system's stability in some sense. However, a standard method for extracting SFGs from a transcriptome data with high reproducibility has not been established. Here, I propose two novel methods for extracting SFGs. The first method has two steps: selection of remarkably fluctuated genes and extraction of synchronized gene clusters. The other method is based on principal component analysis. It has been confirmed that the two methods have high extraction performance for artificial data and a moderate level of reproducibility for real data. The proposed methods will help to extract candidate genes related to the stability and homeostasis in living organisms.

著者

林衡 [述]

巻号頁・発行日

1867

著者

村瀬 鋼

出版者

成城大学

雑誌

Azur = Azur

巻号頁・発行日

no.13, pp.59-76, 2012

著者

伴信友

出版者

伴信友 写

巻号頁・発行日

1838

著者

新井 邦夫 丸井 信雄

出版者

東京都立大学都市研究センター

雑誌

総合都市研究 (ISSN:03863506)

巻号頁・発行日

no.5, pp.133-144, 1978

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都内にある地下空間のなかで最も浸水の危険性の高い江東地区の地下鉄(都営1号線,営団東西線,都営10号線)の,大地震後の浸水危険度について考察した。これらの地下鉄では高潮や洪水に備え,駅出入口の止水板もしくは防水扉,トンネル内の強制換気法,トンネル内の防水扉等さまざまの防水対策がこうじられている。大地震後,堤防の欠壊による地表への浸水や,駅出入口や構築の亀裂からのトンネル内への浸水が発生することを想定し,対象となる駅の地表や,トンネル内の標高とその標高以下の空間体積との関係を図化した。これらの図は駅出入口付近や駅ホームが水没するために必要な総水量を与えるものであるが,発災後の対策に際し極めて有用であると思われる。水没のための必要水量を指標として各駅の浸水危険度を検討した。都営1号線では押上駅の地表部,浅草駅ホーム,東西線では南砂町駅と東陽町駅の地表部,および木場駅ホーム,都営10号線では西大島駅と大島駅の地表部,浜町駅,菊川駅,西大島駅の各ホームが他に比べ早く水没するとの結論を得た。さらにこれらの結論をもとに都営1号線では本所吾妻橋駅,東西線では門前仲町駅,都営10号線では住吉駅を乗客避難の集結地とすべきであり,これらにおける避難誘導法の現実的確立を急ぐべきであることを指摘した。The danger of subway tunnels to be submerged following a heavy earthqake is being considered. The investigated subways are the Metropolitan No.1,No.10 Lines and the Tozai Line which run beneath the area known as the Koto District. In these subways various contermeasures against high tides and/or floods such as the installations of water tight doors at station entrances,water-tight gates in the tunnels and artificial ventilation systems have taken shape,since the area is located on low land that varies from +2 to -3 meter above mean sea level. In respect to the ground surface around each entrance of all stations and each tunnel the relationships between level and space volume below the level were shown graphically. From these graphs it is easy to compute the total water volume needed to flood the ground area bounded by embankments or each platform of stations in question. And the graphs may be useful for emergency measures after the occurrence of water intrusion to the area or into the tunnels. The danger of flooding for each station is investigated using the water volume described above. The ground surfaces around the stations of Oshiage,Minamisunamachi,Toyocho,Nishioshima and Oshima and the station platforms of Asakusa,Kiba,Hamacho,Kikukawa and Nishioshima may be more perilous than the others. The stations of Honjoazumabashi,Monzennakacho and Sumiyoshi may basicall serve as a place of refuge for passengers after the occurrence of a heavy earthquake.

著者

坂本 静男 西山 逸成

出版者

一般社団法人 日本体育学会

雑誌

日本体育学会大会予稿集

巻号頁・発行日

vol.46, 1995

著者

田中 佑弥

出版者

武庫川臨床教育学会

雑誌

臨床教育学論集 = Journal of clinical education research (ISSN:18823874)

巻号頁・発行日

no.10, pp.25-37, 2018-12-25

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奥地圭子は、日本の代表的なフリースクールである東京シューレを1985 年に開設したことで知られている。本稿では、教育雑誌『ひと』(太郎次郎社)における記述に着目して、フリースクール開設以前の奥地圭子の教育観を考察した。登校拒否児の母親であり、小学校教師であること、つまり「母親教師」であることを通して、奥地の教育観は培われていった。

著者

田畠 健太郎

出版者

ストラータ同人会

雑誌

Strata

巻号頁・発行日

vol.22, pp.34-54, 2008-12-15

出版者

伴信友写

出版者

日経BP社

雑誌

日経レストラン (ISSN:09147845)

巻号頁・発行日

no.398, pp.135-140, 2008-05

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「第14回 日経レストラン メニューグランプリ」決勝戦が、3月13日、「HOTERES JAPAN2008」会場内で開催された。「プロの知恵」をテーマに、8人の料理人が腕を競った。 審査員の村田吉弘さん(菊乃井 代表取締役)は、「非常に新しい、ユニークな発想の料理が多く、高レベルの戦い。我々も"パクれる"作品が多かった」と講評。

出版者

北海道新聞社

巻号頁・発行日

1949

著者

Beverly M. HITTLE Gordon L. GILLESPIE

出版者

National Institute of Occupational Safety and Health

雑誌

Industrial Health (ISSN:00198366)

巻号頁・発行日

vol.56, no.6, pp.512-523, 2018 (Released:2018-11-21)

参考文献数

53

被引用文献数

43

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Shift workers are at risk for developing serious health issues due to short sleep. One cause of short sleep is circadian misalignment: sleep time is not synchronized with the body’s natural circadian rhythms. Although circadian rhythms are strongly driven by the light/dark cycle, humans have individualized sleep time preferences (chronotypes) based on genetics, development, and external influences. Evening chronotype individuals fall asleep later than average and have a higher risk for developing various noncommunicable diseases. What is unclear is the association between chronotype, shift work, and risks for acquiring chronic conditions. This review is focused on shift worker chronotype and associations with obesity. Because of the paucity of research, other health issues connected with circadian misalignment were included, allowing for a total of 21 research studies. Evidence from this review supports chronotype and certain health issues are associated with shift work, even after adjusting for short sleep duration. In addition, there is evidence to support future research on how shift worker chronotype matched with shift timing impacts worker health. Through better understanding of this interface, occupational health providers can provide more comprehensive worker education on the risks associated with shift work and sleep disturbances.

出版者

日経BP社

雑誌

日経レストラン (ISSN:09147845)

巻号頁・発行日

no.412, pp.85-98, 2009-05

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「第15回 日経レストラン メニューグランプリ」決勝戦を、3月25日に開催した(会場は、東京・中野の織田調理師専門学校)。今回のテーマは「バリュー2009 〜プロが創る新たな価値〜」。最終選考に残った10人が、勝負に臨んだ。 審査は、「どの部分にバリューが感じられるか」の観点から進み、白熱した。

著者

(明) 龔廷賢 撰

出版者

梅壽 活字印

巻号頁・発行日

vol.[1], 1620

著者

吉村 良孝 本田 倫江 下瀬 祐子

出版者

厚生労働統計協会

雑誌

厚生の指標 (ISSN:04526104)

巻号頁・発行日

vol.60, no.3, pp.18-22, 2013-03

著者

梅亭金鵞 作

出版者

刊

巻号頁・発行日

vol.五編上,

著者

坂井 一 黒川 勝己

出版者

地学団体研究会

雑誌

地球科学 (ISSN:03666611)

巻号頁・発行日

vol.56, no.4, pp.217-230, 2002

参考文献数

32

被引用文献数

4

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魚沼層群のSK110と上総層群のKd25火山灰層,およびSK100とKd24火山灰層の対比を検討した.これらの火山灰層はいずれも黒雲母の目立つガラス質火山灰層である.SK110とKd25およびその広域対比が指摘されている火山灰層については,記載岩石学的特徴や火山ガラスの化学組成から対比が検証され,さらにSK110とKd25とは,黒雲母の化学組成(Mg#=41.8-43.6)も一致する.SK100とKd24の対比については,火山ガラスに多孔質型が多いことや,化学組成の一致,有色鉱物に少量の褐れん石を含む共通性から対比できると考えられる.またSK100とKd24の黒雲母の化学組成(Mg#=26.0-36.0)も類似の組成範囲にある.なおSK100とKd24の火山ガラスや黒雲母,斜方輝石は,SK110やKd25に比べて,より低いMg#値を示す.SK100やKd24は,今後より広い地域にわたって見出されることが期待される.

著者

杉山 喜一 神林 勲 岡嶋 恒 横田 正義 前上里 直 須田 康之 及川 勝也 岡安 多香子 佐々木 貴子 野寺 克美 行徳 義朗

出版者

北海道教育大学

雑誌

北海道教育大学紀要. 教育科学編 (ISSN:13442554)

巻号頁・発行日

vol.63, no.2, pp.85-93, 2013-02

著者

大崎 晃

出版者

学術雑誌目次速報データベース由来

雑誌

地學雜誌 (ISSN:0022135X)

巻号頁・発行日

vol.109, no.1, pp.87-105, 2000

参考文献数

26

被引用文献数

2 1

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Various studies have been carried out on whaling mainly by American vessels throughout the Atlantic, Pacific and Indian Oceans in the 18th and 19th centuries. The studies cover firstly the natural history of whales; secondly, an enlarged geographical view in accordance with the expansion of operating areas, almanac of whaling activities, and studies on whaling from the standpoint of the social sciences. Naturally, there are many unsolved problems in social science studies with their relatively short history. Nevertheless, the writer seeks to identify-by approaching new resources and references-the conditions that made New England the center of whaling in the 18th and 19th centuries.<BR>The writer wishes to point out that the favorable environment for investors made it possible for them to acquire enough funds to start whaling businesses. In those days, new vessels were built and used ones were purchased by consortiums supported by joint small investments in each vessel. A consortium, unlike companies today, did not try to increase the number of vessels. It dissolved itself when a vessel was no longer used or was sold. There are two explanatory theories; deficiency of capital for ship building and losses due to various accidents. These two theories do not necessarily seem to match the facts. As for the former case, investors allocated small amounts for many vessels at the same time. As for the latter, there already existed insurance to cover sea accidents although not a poor hunt. Accordingly, many consortiums were repeatedly established or dissolved. At the same time, each consortium provided good opportunities for investors.<BR>Under these circumstances, no individual risked owning a whaling vessel by investing a substantial amount. Instead, investors left the management of their vessels to an agent. The agent was one of the investors in a consortium, but his investment was modest. He was also a merchant who handled supplies of necessities for voyages of vessels, and sales of whale products upon a vessel's return. Therefore, an agent, like other investors, tried to expand his sales by investing small amounts in many vessels, and at the same time protected himself from a poor catch. Even if a loss was incurred, it was covered by profits from other vessels and sales. Thus the fund provided by other investors was also protected.<BR>Profits from whaling to the crew members were distributed by a lay system. According to this system the crew had to share the risks of fluctuating whaling fortunes, but even in this case the investors' fund was always protected.<BR>Conventional social restrictions upon employing crew members had already been removed, and a new employment custom based on a distribution of profit was established. The contract between the whaling management and the crew was renewed at each voyage. In this case, head hunters were active. They provided crew members with information on the personal experience of each master of a vessel, and on the productivity of each vessel. These facts were very important because they affected the distribution of profits, and the crew selected the next vessel based on such information provided by head hunters.<BR>Under such circumstances, investments encouraged further investments in New England, and whaling developed into an industry. New England attracted many people with professional skills and knowledge, and became the center of the American whaling business. It lasted much longer in the region than in any other parts of the country.