著者

山田 豊

出版者

デジタルアーカイブ学会

雑誌

デジタルアーカイブ学会誌 (ISSN:24329762)

巻号頁・発行日

vol.7, no.3, pp.129-133, 2023-08-01 (Released:2023-10-11)

参考文献数

19

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女性の手にイレズミを施し、それが、『女性のあこがれの象徴』だった。そんな普通の日々が、ある日を境に、180°逆転し、悪と化してしまった。入れているものは警察に検挙され、入れていることに恥ずかしさを感じるようになった。1899年(明治32年)に禁止令が発令され、沖縄の女性の手からハジチが消滅した。その沖縄の失われた文化について、デジタルアーカイブの必要性を考える。

著者

宮本 聖二

出版者

デジタルアーカイブ学会

雑誌

デジタルアーカイブ学会誌 (ISSN:24329762)

巻号頁・発行日

vol.7, no.3, pp.124-128, 2023-08-01 (Released:2023-10-11)

著者

水島 久光

出版者

デジタルアーカイブ学会

雑誌

デジタルアーカイブ学会誌 (ISSN:24329762)

巻号頁・発行日

vol.7, no.3, pp.121-123, 2023-08-01 (Released:2023-10-11)

参考文献数

4

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第7巻3号特集「デジタルアーカイブの未来と沖縄」の企画主旨(昨年の大会との連続性)と問題提起、および各論の紹介。

出版者

デジタルアーカイブ学会

雑誌

デジタルアーカイブ学会誌 (ISSN:24329762)

巻号頁・発行日

vol.7, no.3, pp.119-120, 2023-08-01 (Released:2023-10-11)

著者

吉見 俊哉

出版者

デジタルアーカイブ学会

雑誌

デジタルアーカイブ学会誌 (ISSN:24329762)

巻号頁・発行日

vol.7, no.3, pp.117-118, 2023-08-01 (Released:2023-10-11)

著者

中西 雅之

出版者

公益社団法人 日本薬学会

雑誌

YAKUGAKU ZASSHI (ISSN:00316903)

巻号頁・発行日

vol.127, no.6, pp.977-982, 2007 (Released:2007-06-01)

参考文献数

25

被引用文献数

10 12

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S-Adenosyl-L-homocysteine (SAH) hydrolase catalyzes breakdown of SAH, which arises after S-adenosylmethionine-dependent methylation, into adenosine and homocysteine. The enzyme activity is required for both metabolic pathway of sulfur-containing amino acids and a variety of biological methylations. Because of the essential roles of SAH hydrolase for living cells, inhibitors of SAH hydrolase are expected to be antimicrobial drugs, especially for viruses and malaria parasite. Our research focused on the development of new antimalarials based on the SAH hydrolase inhibition. Malaria parasite employs SAH hydrolase of itself for coping with the toxicity of SAH, so that the target offers opportunities for chemotherapy if structural differences are exploited between the parasite and human enzymes. In vitro screens of nucleoside analogs resulted in moderate but selective inhibition for recombinant SAH hydrolase of malaria parasite, Plasmodium falciparum, by 2-position substituted adenosine analogs. Similar selectivity was observed in the growth inhibition assay of cultured cells. Following crystal structure analysis of the parasite SAH hydrolase discovered an additional space, which is located near the 2-position of the adenine-ring, in the substrate binding pocket. Mutagenic analysis of the amino acid residue forming the additional space confirmed that the inhibition selectivity is due to the difference of only one amino acid residue, between Cys59 in P. falciparum and Thr60 in human. For developing antimalarial drugs, it might be suitable to select target from pathways that are present in the parasite but absent from humans; nevertheless, even if the target was common in parasite and host, slight structural difference such as single amino acid variation is likely to be available for improving inhibitor selectivity.

著者

中里 祐紀

出版者

一般社団法人 大学教育学会

雑誌

大学教育学会誌 (ISSN:13442449)

巻号頁・発行日

vol.44, no.1, pp.140-149, 2022 (Released:2023-06-23)

参考文献数

28

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This paper examines the effectiveness and the continuity of student-engaged faculty development (FD) organizations by considering the case of Okayama Universityʼs student-engaged FD organization, an official organization that has been active for around twenty years. This study adopted a research methodology that involved disclosure of internal institutional documents (e.g., meeting documents) and procuring these to conduct a detailed analysis to overcome data limitations. The main findings from the analysis are as follows: (1) Okayama Universityʼs student-engaged FD organization was established as part of the universityʼs FD and a certain level of quality was demanded with respect to the student proposals; (2) Diverse activities have been conducted in the last two decades that have contributed to the promotion and enhancement of the universityʼs FD while incorporating the studentsʼ perspective; (3) Students who participated have been able to improve the quality of their proposals by surveying general students and departments, generalizing ideas that began as personal issues of interest and repeatedly discussing such ideas during meetings with the students, faculty, and staff members of the organization so that these could serve as formal proposals of an official committee submitted to the university; (4) While the student-engaged FD organization seeks to procure more participation in the form of initiatives by the students, it was found that less opportunities to participate in the discussions are being provided to the students.

著者

外山 明

出版者

大阪経大学会

雑誌

大阪経大論集 (ISSN:04747909)

巻号頁・発行日

vol.72, no.3, pp.93-117, 2021 (Released:2021-09-28)

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半導体産業黎明期の1950年代に米国で発行された『トランジスタ・テクノロジ』という本がある。これはベル研究所とウエスタン・エレクトロニクス社が,発明して間もないトランジスタの製造技術を,技術援助契約(特許契約)をした企業に伝授するために発行した教本である。また,創業期のソニー(当時の社名は東京通信工業)が,国内他社に先駆けて同契約を結んで高額な特許使用料の対価として入手し,トランジスタ,そしてそれを使用したトランジスタラジオを早期に開発・発売をして世界に名を馳せるきっかけとなった本としても知られている。当時同社が受け取った『トランジスタ・テクノロジ』は,国内の多くの文献では全3巻と記され,言わば通説となっている。しかし,この通説は誤りであり,発行された背景や原書に記載された内容等を踏まえると全2巻が正しいはずである。本稿ではこの仮説を検証した上で,国内で誤った通説が広がった原因まで追究した。

著者

Tomohiro Kondo Hirokazu Higuchi

出版者

The Japanese Society for Horticultural Science

雑誌

The Horticulture Journal (ISSN:21890102)

巻号頁・発行日

pp.QH-093, (Released:2023-10-11)

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Passion fruit has edible arils with a complicated structure. Each aril has three different membranes; an external membrane, an internal membrane with a fimbriate structure at the basal area, and a transparent membrane that completely envelops the seed. It was reported that juice quality, including organic acid and sugar contents, varied depending on the extraction method. So, organic acid and sugar are potentially localized inside the aril. In this study, using three cultivars (purple passion fruit, yellow passion fruit, and ‘Summer Queen’, a hybrid variety between the two), juice qualities of different aril parts were determined. The aril was separated into three parts, that is, the outer pulp (OP), the distal part of the inner pulp (DIP), and the basal part of the inner pulp (BIP). The OP included the external membrane and the juice held by this membrane. The DIP surrounding the seed and the BIP was a fimbriate structure attached to the internal membrane. In all varieties, titratable acidity (TA) and citric acid content at DIP were higher than those at OP and BIP, although there were some differences among the varieties. Malic acid content did not vary among the parts. Total soluble solid content (TSS) at BIP was the highest among the parts, and glucose, sucrose, and fructose contents at DIP were lower than those at BIP. Purple passion fruit had a high juice content at OP and the yellow cultivar had high juice content at DIP, while the hybrid between the two showed intermediate characteristics. Organic acid and sugar were localized inside the aril in the passion fruit cultivars; the citric acid content and TA at DIP were higher than those at OP and BIP, and TSS at BIP was higher than those at DIP and OP. Therefore, adjusting the juice extraction intensity may be needed depending on the required juice quality.

著者

上原 公子

出版者

日本教育政策学会

雑誌

日本教育政策学会年報 (ISSN:24241474)

巻号頁・発行日

vol.26, pp.10-24, 2019 (Released:2020-06-20)

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The improper control of Ishiharaʼs Tokyo metropolitan government has completely destroyed democratic and independent education in the country. However, this means that the Board of Educationʼs mission is the old Fundamental Law of Education, Article 10ʠEducation shall not be subject to improper control but it shall be directly responsible to the whole peopleʡ. It is also a question of whether we were able to protect or not. Once, Kunitachi supported the decision of the board of education which chose the four town system at the time of ʼKinpyouʼ. There was a trusting relationship between the Board of Education and the public through an incessant dialogue. Ishiharaʼs intervention has systematically divided the relationship by capturing the superintendent of education, dispatching the staff of the guidance section from the Metropolitan Education Commission, conducting short-term transfer personnel affairs of the teacher and the principal, vetoing the election of the education committee of the assembly, and conducting attacks using the media. By doing these things, the Board of Education and education itself were taken away from the local citizens. The only way to counter this is to foster the power of citizen autonomy through open education.

著者

福井 直樹

出版者

日本コミュニケーション障害学会

雑誌

コミュニケーション障害学 (ISSN:13478451)

巻号頁・発行日

vol.22, no.2, pp.85-92, 2005-08-31 (Released:2009-11-19)

参考文献数

12

被引用文献数

1

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現代言語学の基本目標を説明するとともに,20世紀における言語理論の進展を概説した.Saussureが「社会的所産」とみなした言語構造を人間の脳内に実在する機能(再帰的生成システム)ととらえ,それに関する明示的説明理論の構築を目指したのが生成文法理論であるが,「より深い説明」を目指す継続的試みが現在に至る理論的変遷の根本的原動力になっていることを論じた.その上で,言語学と言語障害学が将来さらに有機的に連携するためには,言語脳科学ともいうべき分野の確立が必須であるとともに,今までの生成文法理論には欠如していた「言語の社会性」を厳密に研究するためのモデル構築が望まれるということも指摘した.

著者

江川 隆男

出版者

日仏哲学会

雑誌

フランス哲学・思想研究 (ISSN:13431773)

巻号頁・発行日

vol.27, pp.260-264, 2022-09-01 (Released:2022-10-01)

著者

侘美 靖 森谷 きよし

出版者

日本生気象学会

雑誌

日本生気象学会雑誌 (ISSN:03891313)

巻号頁・発行日

vol.42, no.4, pp.145-157, 2005 (Released:2006-02-18)

参考文献数

26

被引用文献数

1

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本研究は,中高年者が多数参加し,2月から約4ヶ月間にわたって週2回の踊り練習を継続する北海道のYOSAKOIソーランチームを対象に,踊りの運動強度としての心拍数(HR)と腰部位の合成加速度,また踊り練習への参加による運動量や体力向上を検討した.中年踊り子の演舞時HR最高値が180拍/分を超えるほど踊りの運動強度は高く,HRと腰部位加速度値は正相関していた.また,演舞中HR最高値は,練習時に比べ祭り時は20拍/分ほど高くなる場合もあり,緊張感と気象条件の影響が推察された.被験者NR(50歳女性)の練習日の1日当たりの歩数と運動によるエネルギー消費量は,非練習日に比べ有意に増加した.YOSAKOIソーラン祭り参加者の体力レベルは,約4ヶ月の間に改善していた.YOSAKOIソーラン踊り練習と祭りへの参加により,冬期に運動不足になりがちな寒冷地域に住む人々の健康増進に効果のあることが示唆された.

著者

石田 佐恵子

出版者

関西社会学会

雑誌

フォーラム現代社会学 (ISSN:13474057)

巻号頁・発行日

vol.6, pp.35-44, 2007-05-26 (Released:2017-09-22)

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メディア文化が高度に細分化・多様化する現代において、年齢層(世代)ごとに明瞭に区分可能な文化を同定することははたして可能なのだろうか。若者文化論、対抗文化論など、かつて世代ごとに区分可能な文化が観察可能であったとして、それらはまさしくマス(=大量)文化を形成するメディア商品とその市場が可能にしていた現象に過ぎなかったのではないか。本報告では、文化研究における差異の問題、世代文化論の困難(問題点)を考察する。世代論の困難は、(1)俗流若者論、(2)世代主義、(3)女の系譜の忘却、の3つの論点にまとめられる。また、1970年代から2000年代までの、世代論のマーケット的意味を概括する。さらに、時代ごとの共通経験や時間感覚を文化研究に反映させるための方法論的な可能性について、メディアの共通経験をキーワードに論ずる。

著者

池上 博司

出版者

一般社団法人 日本内科学会

雑誌

日本内科学会雑誌 (ISSN:00215384)

巻号頁・発行日

vol.108, no.9, pp.1946-1953, 2019-09-10 (Released:2020-09-10)

参考文献数

10

著者

山本 征孝 藤本 康浩 森 義統 椿野 稔

出版者

日本義肢装具学会

雑誌

日本義肢装具学会誌 (ISSN:09104720)

巻号頁・発行日

vol.33, no.1, pp.64-66, 2017-01-01 (Released:2018-01-15)

参考文献数

9

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慢性期脳卒中片麻痺患者1名を対象に,短下肢装具と腓腹筋への機能的電気刺激を併用した歩行練習の治療効果を検討した.シングルケースデザインのABA’B’デザインを使用し,短下肢装具を使用した歩行練習のみを行うA·A’期と短下肢装具と腓腹筋への機能的電気刺激を併用した歩行練習を行うB·B’期で治療効果の比較検討を行った.その結果,最大歩行速度,歩幅がB·B’期に増加する傾向を認めた.歩行率に関しては,いずれの時期においても変化は認められなかった.本症例において,短下肢装具と腓腹筋への機能的電気刺激を併用した歩行練習は,歩行能力の改善に有効であった.

著者

Ichiro Umemura Shunsuke Eguchi Yohei Morita Hironobu Mitani Kazuma Iekushi Takao Kato

出版者

The Japanese Circulation Society

雑誌

Circulation Reports (ISSN:24340790)

巻号頁・発行日

pp.CR-23-0066, (Released:2023-09-21)

参考文献数

30

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Background: Triple combination therapy with a renin–angiotensin system modulator, a β-blocker, and a mineralocorticoid receptor antagonist is currently recommended for patients with heart failure (HF) with reduced ejection fraction. However, there is limited evidence on the extent to which triple combination therapy is currently prescribed to patients at the time of discharge from hospital in Japan.Methods and Results: Japanese patients hospitalized for HF (n=3,582) were evaluated in subgroups defined by left ventricular ejection fraction (LVEF) using anonymized claims and electronic health record data. At discharge, triple combination therapy prescription rates were low (40.4%, 30.0%, 20.8%, 14.0%, and 12.5% for patients with LVEF <30%, 30–<40%, 40–<50%, 50–<60%, and ≥60%, respectively). Advanced age, lower levels of B-type natriuretic peptide, and renal impairment were all significantly associated with lower rates of triple combination therapy use in the overall population. There were no significant differences in rehospitalization rates between LVEF subgroups; however, triple combination therapy use was associated with a significantly reduced risk of rehospitalization for HF in patients with LVEF <30%, 30–<40%, and 40–<50%.Conclusions: The use of triple combination therapy was significantly associated with a lower risk of rehospitalization for HF within 1 year of discharge in patients with LVEF <30%, 30–<40%, and 40–<50%. However, patients were undertreated with triple combination therapy.

著者

Mayuka Masuda Hiroyuki Yamamoto Akiko Masumoto Tomofumi Takaya

出版者

The Japanese Circulation Society

雑誌

Circulation Reports (ISSN:24340790)

巻号頁・発行日

pp.CR-23-0075, (Released:2023-09-28)

著者

岡 通太郎

出版者

一般財団法人 アジア政経学会

雑誌

アジア研究 (ISSN:00449237)

巻号頁・発行日

vol.52, no.1, pp.44-61, 2006-01-31 (Released:2014-09-30)

参考文献数

22

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According to the Agricultural Wage in India, published yearly by the Indian Government, the agricultural wage rate in central Gujarat remains around Rs. 24–30 per day. This is much lower than the rates in other areas such as northern and peninsular Gujarat, where the rate has risen sharply, reaching Rs. 60 during the 1990s. It is also perhaps surprising that the agri cultural wage in central Gujarat remains low even after the recent increase in rural non-farm employment opportunities that provide wages of around Rs. 60–200 per day. This suggests that the ‘trickledown’ effect of economic development to the agricultural labor classes is not working well. Why does the agricultural wage rate in central Gujarat remain at such a low level despite the opportunities of high wage, non-farm employment? Why doesn’t the‘ trickle-down’ effect work well in central Gujarat? This paper aims to examine this question through an intensive field survey at a sample village in central Gujarat.The paper addresses this question by considering two factors, one external the other in ternal.The external factor is the limitation of non-farm employment opportunities. If these opportunities are separated from agricultural labor markets by high barriers (e.g. high education requirements), the ‘trickle-down’ effect will not work well. The internal factor is the local informal credit institution. As K. Basu (1983) explained in his ‘inter-linkage theory’, if the agricultural laborer is in debt to his employer with a low interest rate, his wage will also be low because the employee gets the benefit of low interest.Investigation showed that 44% of the agricultural laboring classes (landless and marginal farmers) are working in non-farm sectors, and 40% out of the 44% are employed in high-wage and low-education sectors. No clear segmentation is found. On the other hand, the internal factor has a stronger effect on low agricultural wages. There is a local informal credit institution called Kaymi that exists especially in rural areas of central Gujarat. Under this local institution, 22% of agricultural laborers are in debt to their employers free of interest. Evaluating the benefit of interest-free credit that is enjoyed by these laborers gives their ‘effective wage’ to be Rs. 48, which is close to the wage of non-farm employment. This local institution also affects low wages of the other 78% of agricultural labors. With restricted opportunities for the agricultural labor classes to get formal loans, this local informal institution is the only way for them to obtain credit and ease risk burdens associated with their livelihood. This paper also asserts that this kind of ‘social institution’ has been developed upon long-term social relationships that are based onland distribution inequity, which closely corresponds to caste segmentation.

著者

伊庭 斉志 井上 博允

出版者

一般社団法人 人工知能学会

雑誌

人工知能 (ISSN:21882266)

巻号頁・発行日

vol.5, no.3, pp.300-310, 1990-05-01 (Released:2020-09-29)

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An algebraic approach for geometric reasoning is presented. The purpose of this study is to avoid the usual difficulties which appear in the symbolic approach for machine handling of geometric concepts, such as appropriate representation for transformation-invariant properties of geometric concepts, formal interpretation of heuristics, and finding the tricky auxiliary lines for geometrical problem solving. In order to solve these difficulties we choose Wu's method as the base of our algebraic approach, and have realized an effective geometric reasoning. In this paper, we describe the basic concept of Wu's method, advantages of this algebraic approach, and usefulness for theorem proving. We also show the validity of our approach by applying it to learning-from-example of some heuristic rules in computer vision.