著者
大塚 明子 熊野 宏昭
出版者
一般社団法人 日本認知・行動療法学会
雑誌
行動療法研究 (ISSN:09106529)
巻号頁・発行日
vol.27, no.2, pp.83-96, 2001-09-30 (Released:2019-04-06)

本研究では、幼少時、吹雪の中で突風の向かい風のために息ができなくなるという外湯的体験に関連した予期不安からパニック発作を繰り返す「パニック障害の既往歴のない広場恐怖」に対して、薬物療法と認知行動療法の併用で軽快した症例を報告し、認知行動療法の介入効果について検討した。具体的に用いられた技法は、心理教育、腹式呼吸、自律訓練法、系統的脱感作法、エクスポージャー、認知再構成法であった。本症例の治療経過からは、(1)心理教育やリラクセーション法によって、緊張・過敏さの低減、対処法の獲得、さらなる治療への動機づけがなされた後、(2)系統的脱感作法、エクスポージャーによって外傷的体験に関わる記憶が正常化され、(3)さらに認知再構成法により予期不安が改善されたことによって、広場恐怖全般の軽快に至ったものと考えられた。以上より、本症例のように広場恐怖の維持要因の中核である予期不安の背景に幼児期の外傷的体験が存在する場合には、その影響を緩和するための介入が必要であることが示唆された。
著者
平山 祐一郎
出版者
日本読書学会
雑誌
読書科学 (ISSN:0387284X)
巻号頁・発行日
vol.56, no.2, pp.55-64, 2015-01-31 (Released:2017-02-08)
参考文献数
4
著者
長谷川 光広
出版者
一般社団法人日本脳神経外科コングレス
雑誌
脳神経外科ジャーナル (ISSN:0917950X)
巻号頁・発行日
vol.26, no.6, pp.419-429, 2017 (Released:2017-06-25)
参考文献数
34
被引用文献数
9 5

眼窩内腫瘍はまれな疾患でありながら, 多種多様な病理学的特徴を含み, 病変の性質により治療方針は大きく異なる. 炎症性疾患やリンパ増殖性疾患 (特に最近注目されるIgG4関連疾患, MALTリンパ腫など) の鑑別と悪性度判定に生検は必須であり, その他の腫瘍性疾患には腫瘍摘出のみならず眼窩内容廓清術に至るまで多岐にわたる手術法がある. 経眼窩的, 経頭蓋的アプローチに加えて, 近年, 進歩の目覚ましい神経内視鏡下手術や頭蓋底手術を含めた各手術法の利点, 欠点を十分理解することが重要である. 全摘出を目指すべき疾患には, 病理学的には血管病変 (血管腫, 静脈瘤など), 良性 (髄膜腫, 神経鞘腫など) ならびに悪性腫瘍 (癌腫, 肉腫, 転移など) が挙げられる. また, 頭蓋内から眼窩に伸展するもの, 副鼻腔・鼻腔, 側頭窩, 下窩などから眼窩に伸展するものなど, 眼窩内外に主座を置く腫瘍では, 他科との協力が重要となる. 経頭蓋法では, 眼窩縁, 眼窩壁の骨形成的除去, 上眼窩裂, 視神経管の開放などの頭蓋底手術手技に加え, 機能的および美容的な手技も多々含まれる. 本稿では, 筆者の111例の眼窩ならびに眼窩伸展腫瘍性疾患の経験から代表的手術症例を提示し, 実際の眼窩内腫瘍の診断と摘出術における留意点を述べる.
著者
Yuto Ishibashi Shingo Kimura Ikuro Suzuki
出版者
The Japanese Society of Toxicology
雑誌
The Journal of Toxicological Sciences (ISSN:03881350)
巻号頁・発行日
vol.47, no.10, pp.429-437, 2022 (Released:2022-10-01)
参考文献数
28
被引用文献数
1

Antibiotic-associated encephalopathy (AAE) is a central nervous system disorder caused by antibiotics administration and classified into three types based on clinical symptoms. Type 1 AAE causes seizures and myoclonus, type 2 causes psychiatric symptoms, and type 3 is characterized by cerebellar ataxia. In this study, we investigated whether the electrical activity of in vitro human iPSC-derived neurons to antibiotics could be classified based on the 3 types of AAEs classified by clinical symptoms. Glutamatergic, GABAergic neurons and astrocytes differentiated from human iPS cells were seeded on micro-electrode array (MEA). The cumulative administration of 13 different antimicrobials detected changes in neural activity that differed according to AAE type. Next, we classified the antimicrobials by principal component analysis (PCA) and confirmed the AAE type of each agent. We found that Types 1–3 AAE agents were distributed separately. The classification of antibiotics depending on electrophysiological response characteristics was consistent with the clinical practice classification of AAEs. In conclusion, the combination of electrophysiological responses of human iPS cell-derived neural networks measured by MEA plus multivariate analysis methods will effectively detect and classify antibiotics developmental risks.
著者
萬 秀憲 江口 泰輝 砂川 満 河本 知二 古元 嘉昭
出版者
一般社団法人 日本温泉気候物理医学会
雑誌
日本温泉気候物理医学会雑誌 (ISSN:00290343)
巻号頁・発行日
vol.49, no.2, pp.89-94, 1986 (Released:2010-08-06)
参考文献数
11
被引用文献数
1

Artificial CO2-bath was prepared with a tablet (50g): made from sodium bicarbonate and succinic acid, putting simply in plain water bath tub of 100-200 litre at 40C.The effect of artificial CO2-bath was studied in relation to the change in blood lactic acid which is thought to be indicative of the physical fatigue.It has been clearly demonstrated experimentally using rats that the blood lactic acid after exercise is significantly reduced as compared both to a plain and an artificial Na2 SO4-NaHCO3 bathing.A favorable effect of the artificial CO2-bath was also confirmed clinically by a relief from the stiff pain following maximal abdominal muscle exercise.
著者
小野坂 元
出版者
一般財団法人 日本国際政治学会
雑誌
国際政治 (ISSN:04542215)
巻号頁・発行日
vol.2019, no.195, pp.195_123-195_136, 2019-03-25 (Released:2019-05-16)
参考文献数
61

The Shanghai Young Women’s Christian Association (YWCA) that conducted social work in Chinese society was accused of anti-imperialist, radical actions by the Chinese labor movement after the Shanghai riot on May 30, 1925. While Chinese trade unions endorsed the newly established International Labour Organization (ILO), this international legislation for labor standards could not ensure cooperation between the ILO and the Chinese Government and society; the reason being that any labor condition regulations, both domestic and international, did not exist in the International Settlement as extraterritoriality.This paper clarifies the coordination between the ILO and Shanghai YWCA to remedy the lack of legislative protection that Chinese workers faced in the International Settlement of Shanghai. Although, the Factory Act was enacted in 1929, its enforcement was postponed because of Chinese industrial conditions’ conflict with extraterritoriality.Traditional literature has focused on the conflict between national interests and international standards. This approach notes that international organizations’ activities were disrupted by power politics that sought unilateral interests. However, international organizations established after World War I were dysfunctional. I think that international organizations acquired innovative thinking during the Chinese National Revolution in 1920s. The fact is that the ILO and the YWCA aimed to create a Chinese Labour Inspection System as well as transform themselves from euro-centrism to international socialism.Moreover, we need to consider the connection between Chinese nation building and introduction of ILO standards on both Chinese proper land and extraterritorial areas, particularly Shanghai’s International Settlement. The Chinese government aimed to demonstrate their legitimacy as a nation state by enforcing their labor regulations and inspecting foreign factories.Historical examining the Chinese labor problem regarding extraterritoriality, this article explains that the Shanghai YWCA and the ILO’s activities indirectly influenced the improvement of the International Settlement’s social administration and attained the endorsement of enforcing Chinese factory inspection there.Thus, a condition for reshaping multilateral cooperation with the newly established Chinese Government of Nanking in 1928 was created by this international coordination to enforce international labor standards in Shanghai.
著者
田中(斎藤) 理恵子
出版者
経済社会学会
雑誌
経済社会学会年報 (ISSN:09183116)
巻号頁・発行日
vol.41, pp.121-132, 2019 (Released:2021-09-10)

The aim of this article is to explore the relationship between media and gender representation. First of all, I consider the gender differences of castors reading mainstream news on television news programs. Secondly, I analyze the gender representation found in news reports and examine not only “what” is conveyed, but also “how.” Third, I conduct qualitative researches of people working in the media to see how they think about their work, and examine the current situation and issues of the problems. From the point of view, I examines the structural issues of gender norms in the Japanese media, and I would like to consider ways to enable diversity.
著者
美和 千尋 杉村 公也 川村 陽一 出口 晃 岩瀬 敏
出版者
一般社団法人 日本温泉気候物理医学会
雑誌
日本温泉気候物理医学会雑誌 (ISSN:00290343)
巻号頁・発行日
vol.65, no.4, pp.187-193, 2002 (Released:2010-04-30)
参考文献数
19
被引用文献数
1

The purpose of this study was to eliminate factors of accidents during Japanese style bathing of the elderly.We investigated the age-related changes in cardiovascular and thermoregulatory function in response to the bathing at 40°C. We measured the blood pressure and the heart rate using an automatic spygmomanometer, the skin blood flow at the forearm using laser Doppler flowmetry, the tympanic temperature using a thermistor, and the sweat rate at dorsum manus using the ventilated capsule method during bathing at 40°C for 20min in 10 aged (73.5±8.4, mean±SD) and 10 young subjects (19.8±1.8).Aged subjects failed to maintain a stable blood pressure during the immersion in the bathtub. While the heart rate during the bathing significantly changed in the young subjects, no change was observed in the aged subjects. Skin blood flow, tympanic temperature, and sweat rate increased during the bathing for both in the aged and the young subjects, though with smaller changes among aged subjects.These findings suggest that the adaptability of cardiovascular and thermoregulatory functions to heating and hydrostatic pressure during Japanese style bathing decreases with age.
著者
宮代 こずゑ 原田 悦子
出版者
日本認知科学会
雑誌
認知科学 (ISSN:13417924)
巻号頁・発行日
vol.23, no.2, pp.118-134, 2016-06-01 (Released:2016-12-01)
参考文献数
50

To demonstrate the effects of harmonization between a word’s semantics and its typographies on human language word processing, we conducted a series of priming ex-periments using a word-fragment completion task. In the learning phase of experiment 1, words were presented visually as typography was manipulated to be either har-monized or anti-harmonized with a word’s semantics. The results indicated that the visual processing of a word was facilitated when the semantics of the word were harmo-nized with its typographies, compared with instances where they were anti-harmonized,which was observed as a result of decreased phonetic priming. In experiment 2, it was demonstrated that priming was decreased by harmonized typographies, but this decline was canceled by presented speech sounds compared with the results of experiment 1 although neutral speech sound recordings of words were presented with letters visually presented as words. In experiment 3, the harmonization was manipulated using not only letters but also speech sounds that were manipulated to be harmonized or anti-harmonized. The results showed that the processing of letters was interfered with by those harmonized speech sounds. These results imply that greater processing resources were used for the sensory modality that was manipulated its harmonization.
著者
佐藤 秀樹 鈴木 伸一
出版者
一般社団法人 日本健康心理学会
雑誌
Journal of Health Psychology Research (ISSN:21898790)
巻号頁・発行日
vol.33, no.2, pp.93-102, 2021-03-15 (Released:2021-03-13)
参考文献数
29

The differential effects of rumination on attentional breadth was investigated by experimentally manipulating rumination from the perspective of thought content and valences of thinking-time. We randomly assigned 68 undergraduate and graduate students to negative, neutral, long-, and short-time thinking groups. Then, we administered a questionnaire, conducted a rumination manipulation and the modified Attentional Breadth Task. In this task, there are Close and Far conditions that have a narrow and wide attentional range depending on the location of the target stimulus, and ΔAttentional Narrowing Index (ΔANI) representing the differences between the correct response rate for a target in Close and Far conditions are calculated, such that higher ΔANI values indicate a narrower attention range. Results indicated that state rumination and negative emotions worsened and attentional breadth decreased when participants focused on negative thoughts for a long time. Moreover, a causal relationship between rumination and attentional breadth was suggested. Also, factors narrowing attentional breadth through rumination were identified based on the attentional scope model. It is suggested that future studies should consider whether depression or negative cognitive processing is worsened by narrowing attentional breadth.
著者
森 禎章 山路 純子
出版者
保健医療学学会
雑誌
保健医療学雑誌 (ISSN:21850399)
巻号頁・発行日
vol.9, no.1, pp.45-61, 2018-04-01 (Released:2018-04-01)
参考文献数
73

皮膚における侵害受容はAδ線維とC線維の自由神経終末により行われる.Aδ侵害受容器は主に機械刺激に応答し,刺す痛みや速い痛みを生じる.C侵害受容器は熱,冷,化学および機械刺激に応答し,灼けつく痛みや遅い痛みを生じる.侵害受容器の神経終末にはイオンチャネルや受容体が発現しており,機械刺激に対しpiezo1 やASICs などのイオンチャネルが,熱刺激に対しTRPV1〜4 チャネルが,冷刺激に対しTRPM8 とTRPA1 チャネルが,化学刺激に対しASICs,TRPV1,TRPV3,TRPM8,TRPA1 チャネル,ATP 受容体,B2 受容体がこれを受容する.この総説では,侵害受容に関わるイオンチャネルと受容体について,電気生理学的観点から解説する.
著者
加藤 公則
出版者
公益社団法人 日本人間ドック学会
雑誌
人間ドック (Ningen Dock) (ISSN:18801021)
巻号頁・発行日
vol.31, no.4, pp.541-549, 2016 (Released:2017-03-28)
参考文献数
35

Brain natriuretic peptide(BNP)とN terminal(NT)-proBNPは心不全の診断,予後を推定できる有用なバイオマーカーである.しかし,BNPは循環器内科医や一般内科医にとって有用なだけではなく,将来は健診医にとっても有用なバイオマーカーと成り得ると思われる.つまり,BNPやNT-proBNPは心不全と診断できる値より低値で,将来の死亡,心疾患や脳卒中の発症を予測できることが知られてきている.したがって,人間ドックにて高血圧,糖尿病(耐糖能障害も含む),脂質異常症,喫煙などがあり,すでに将来の動脈硬化性疾患の発症リスクのある人は,BNPやNT-proBNPを測定し,もし,それが正常高値にあれば,将来の脳心疾患の発症を防ぐために,さらに厳密なリスク管理を施す必要があると思われる.さらに,BNPは糖代謝とも関連していることが最近知られてきており,将来,糖尿病医にとっても大切なバイオマーカーになる可能性もある.
著者
和佐 好智 弘原海 清
出版者
情報知識学会
雑誌
情報知識学会誌 (ISSN:09171436)
巻号頁・発行日
vol.13, no.2, pp.41-47, 2003-05-12 (Released:2016-12-12)
参考文献数
7
被引用文献数
2 2

岡山理科大学の本研究室では,地震危険予知を試みる方法の一つとして宏観異常現象を利用している.宏観異常現象は,大地震発生前に震源地周辺で多く認められる自然や動物の異常のことである.この宏観異常現象を利用して地震危険予知を行うためには,より迅速な収集・公開システムが必要である.このため,研究室のWebサイト(e-PISCO)上でインターネットを使った宏観異常情報の収集・公開を2000年9月15日より開始した.この収集・公開を可能にしたシステムが宏観異常情報システムである.この宏観異常情報システムの機能強化の内容と,2002年12月までの運用結果を紹介する.
著者
中川 正
出版者
The Human Geographical Society of Japan
雑誌
人文地理 (ISSN:00187216)
巻号頁・発行日
vol.35, no.2, pp.97-115, 1983-04-28 (Released:2009-04-28)
参考文献数
35

The landscapes of two settlements on the eastern shore of Lake Kasumigaura, Funazu and Tega-Shinden, are markedly different. Funazu is an agglomerated settlement surrounded by paddy fields, whereas Tega-Shinden is a scattered settlement with many ponds for carp-farming as well as paddy fields. Among other things, the difference in religious landscapes is notable. Funazu has facilities and stone momuments pertaining to folk religions, whereas Tega-Shinden has a large Buddhist temple. These differences are probably related to the differences in the Buddhist sect to which each group ascribes. People in Funazu are the followers of Tendaishu (or the Tendai Sect), whereas people in Tega-Shinden are Jodo-Shinshu (or the Jodo-Shin Sect) Buddhists. This study attempts to clarify the characteristics of the two settlements represented by their landscapes and discuss how these differences are related to the denominational difference.The procedure is as follows: First, the origins of the settlements and the changes in house distribution are traced in order to ascertain the background the agglomerated and scattered landscapes (Part 2). Secondly, demographic characteristics are discussed in order to understand the people who have created the landscape (Part 3). Thirdly, the characteristics of economic activities, according to occupational structure and the management of agriculture and fishing will be addressed (Part 4). Fourthly, social organization is described, as it has had a direct influence on the religious landscape (Part 5). Finally, by using the previous findings, an analysis of the data will demonstrate how the characteristics of the settlements reflect the religious factors involved in their formation (Part 6). As a result, the differences in the physical and social characteristics of Funazu and Tega-Shinden, as well as the religious influences on the two settlements, will be evident.Funazu originated in the 17th century, or earlier, and has traditionally had an agglomerated landscape. As the number of households had already reached fifty in the late 17th century, the rate of increase after that was slow. People were relatively conservative in their economic activities and had long maintained an agriculturally-oriented occupational pattern. By the 1960s people began to take on outside jobs other then than agriculture. Nevertheless, the agricultural management centered upon rice production has basically not changed. The Tendaishu temple is not so important to these people because they have some folk-belief organizations which have meetings fairly often. However, their members are limited to housewives or middle-aged men. Thus, these characteristics are influenced by folk beliefs as well as Tendaishu. This is partly due to the fact that Tendaishu incorporates characteristics of folk belief to some extent. Such religious influences in Funazu are fairly weak.The ancestors of the people in Tega-Shinden came from Tonami in Etchu (Toyama Prefecture) at the beginning of the 19th century. It is thought that the scattered landscape in Tega-Shinden was transplanted from Tonami which is famous for its scattered landscape. The people tended to marry young and to have many children. As a result, the population increased rapidly, due in part to their Jodo-Shinshu religion which severly prohibited infanticide. People in Tega-Shinden have worked hard and introduced many new practices and techniques. They have expanded their management of agriculture, fishing, and independent business. There are many reasons for this. Their ancestors had no alternative but to work hard to reclaim wasteland, and many branch families had to find new jobs for their livelihood. Among other things, their hard-working spirit may have been influenced by Jodo-Shinshu's intrinsic charactristics as pointed out by K. Naito, a religious sociologist.