著者

Naoki HIROSE Kazuyuki UCHIDA Hideyuki KANEMOTO Koichi OHNO James K. CHAMBERS Hiroyuki NAKAYAMA

出版者

公益社団法人 日本獣医学会

雑誌

Journal of Veterinary Medical Science (ISSN:09167250)

巻号頁・発行日

pp.14-0083, (Released:2014-04-09)

被引用文献数

1 43

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To determine the incidence of hepatic diseases in dogs and cats in Japan, a retrospective study was performed using data of 463 canine and 71 feline liver biopsies at the Veterinary Medical Center of the University of Tokyo. The most common canine hepatic disease was microvascular dysplasia (MVD) and occupied 29.4% of all diagnoses. This terminology might contain “real” MVD and primary portal vein hypoplasia, because these two conditions were difficult to be clearly distinguished histopathologically. Parenchymal and interstitial hepatitis and primary hepatic tumors accounted for 23.5% and 21.0% of the diagnoses, respectively. Parenchymal and interstitial hepatitis occupied 34.1% of non-proliferative canine hepatic diseases, while hepatocellular adenoma and carcinoma were 26.6% and 24.5% of proliferative hepatic diseases, respectively. Breed-specificity was seen in MVD for Yorkshire terrier, Papillon and Toy poodle, in hepatitis for Doberman pinscher and Labrador retriever, in cholangiohepatitis for American cocker spaniel, Miniature schnauzer and Pomeranian, in hepatocellular adenoma for Golden retriever and Shiba and in hepatocellular carcinoma for Shih Tzu. The most common feline liver disease was parenchymal and interstitial hepatitis (45.1% of all diagnoses). Among feline hepatitis, neutrophilic cholangiohepatitis (23.9%), lymphocytic cholangiohepatitis (14.1%) and chronic hepatitis (5.6%) were recorded. Adult polycystic liver disease was 5.6%. Among proliferative diseases in the feline liver (11.3% of the all), lymphoma (4.2%) and primary epithelial tumors (4.2%) including hepatocellular carcinoma, cholangiocellular adenoma and cholangiocellular carcinoma were observed. Hepatic degeneration was 14.1%, and MVD was 12.7%, respectively.

著者

一色 尚次

出版者

日本混相流学会

雑誌

混相流 (ISSN:09142843)

巻号頁・発行日

vol.1, no.2, pp.125-137, 1987-12-15 (Released:2011-02-22)

参考文献数

5

著者

辻 幸和

出版者

公益社団法人 日本コンクリート工学会

雑誌

コンクリートジャーナル (ISSN:00233544)

巻号頁・発行日

vol.12, no.9, pp.46-67, 1974-09-15 (Released:2013-04-26)

参考文献数

173

著者

鈴木 雪恵 山田 奈保子 小針 香菜 鈴木 綾 馬場 陽子 小川 洋 松井 隆道 大森 孝一

出版者

日本聴覚医学会

雑誌

AUDIOLOGY JAPAN (ISSN:03038106)

巻号頁・発行日

vol.54, no.5, pp.483-484, 2011 (Released:2013-12-05)

著者

鄭 顕志 清水 遼 高橋 竜一 石川 冬樹

出版者

日本ソフトウェア科学会

雑誌

コンピュータ ソフトウェア (ISSN:02896540)

巻号頁・発行日

vol.31, no.1, pp.1_49-1_59, 2014-01-27 (Released:2014-03-27)

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実行時に起こる変化を検知し,要求を満たし続けるようソフトウェアの構造・振る舞いを自身で変更するソフトウェアは,自己適応ソフトウェアとして,その有用性が認知されている.自己適応ソフトウェア開発では,従来のアプリケーションロジックに加え,自己適応性のためのロジックを設計する必要がある.本論文では,近年特にソフトウェア工学の分野で議論されている,自己適応ソフトウェアのための自己適応性設計に関する研究動向を調査する.本論文では,自己適応性のロジックをモデル化する手法として広く用いられている,Monitor-Analyze-Plan-Execute-Knowledgeループの観点から,各要素の概要,研究課題,既存研究のアプローチを紹介し,今後の研究課題について議論する.

著者

Masahiko TANAKA Hangfeng LUO Shuhei INADA Akihiro NAKATSUKA

出版者

ISCM Forum

雑誌

Innovation and Supply Chain Management (ISSN:21870969)

巻号頁・発行日

vol.7, no.1, pp.25-31, 2013-03-31 (Released:2014-04-02)

参考文献数

20

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In this paper, we consider the customer call center operation which is one of the personal computer enduser services. We deal with the problem as a case study where the optimal allocation of the call center staffwhich is called agents is determined. This previous proposed model was to provide the optimal agents' allocation for the call center service based on queuing (Erlang loss formula) [18, 19] and linear programming theory [20]. Here, besides it,we're going to address or examine the mode, considering the queuing space of not-using phones or the phones that no agents are using and the repeated calls that the customers would call when they couldn't reach any agents directly or immediately, and they couldn't even get into the queuing space of not-using phones. Then we show the effectiveness or the extent of the effectiveness of the model.

著者

Chihiro WATANABE

出版者

ISCM Forum

雑誌

Innovation and Supply Chain Management (ISSN:21870969)

巻号頁・発行日

vol.7, no.3, pp.92-104, 2013-09-30 (Released:2014-04-02)

参考文献数

27

被引用文献数

2 10

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Abstract: Dramatic advancement of the Internet has generated global simultaneous dependency on information technology (IT) which has, contrary to anticipation, resulted in the bi-polarization between IT advanced economies and IT growing economies. While the latter enjoy a virtuous cycle between advancement of IT and its productivity increase,IT advanced economies have fallen into a pit of a vicious cycle as further advancement of IT decreases its productivity. Consequently, countries in IT advanced economies suffer economic stagnation. Similar bi-polarization derived from beyond anticipation issue can also be observed in business performance in high-technology firms. Aiming at elucidating the inside the black box of the foregoing growth engine resulting in bi-polarization, an empirical analysis utilizing a new approach integrating techno-metrics, psychophysiology and advanced monitoring techniques is demonstrated thereby insightful suggestion to the above engine is provided. Innovation-consumption co-evolution based on co-evolutionary acclimatization strategy is suggested to be essential for a resilient business while maintaining efficiency. A platform toward this resilient business model is proposed. Dramatic advancement of the Internet has generated global simultaneous dependency on information technology (IT) which has, contrary to anticipation, resulted in the bi-polarization between IT advanced economies and IT growing economies. While the latter enjoy a virtuous cycle between advancement of IT and its productivity increase,IT advanced economies have fallen into a pit of a vicious cycle as further advancement of IT decreases its productivity.

著者

Yoshiki YAMAGATA Hajime SEYA

出版者

ISCM Forum

雑誌

Innovation and Supply Chain Management (ISSN:21870969)

巻号頁・発行日

vol.7, no.3, pp.75-82, 2013-09-30 (Released:2014-04-02)

参考文献数

21

被引用文献数

4 8

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This paper extends the concept of our proposed (Yamagata and Seya, 2012) community-based disaster resilient electricity sharing system (DRESS) as a complement or alternative to a feed-in tariff(FiT) to achieve CO2-neutral transportation in cities. In our proposed system, electricity generated from widely introduced solar photovoltaic panels (PVs) is stored in the“cars not in use ”in a city. For example, almost half of the cars in the central Tokyo metropolitan area are used only on weekends and thus are kept parked during weekdays. These cars represent a huge new potential storage depot if they were replaced by electric vehicles (EVs), that is, they could be used as storage batteries in a V2G system. The present study extends our proposed system in the following two senses. Firstly, different from Yamagata and Seya (2012), this paper uses actual ground area data (footprint) of each building to estimate PV supply, which may lead to more accurate estimations. The results show that although the entire electricity surplus (PV supply minus demand) could be stored without waste if 12% of the EVs not in use were utilized as storage batteries at an aggregate (city) level,there exist significant regional mismatches at the local district level. Hence secondly, based on the geographical PV supply-demand estimates, this paper analyses the possibility of local electricity sharing by looking at the geographical distribution of high-storage potential areas using a spatial clustering technique. This paper extends the concept of our proposed (Yamagata and Seya, 2012) community-based disaster resilient electricity sharing system (DRESS) as a complement or alternative to a feed-in tariff(FiT) to achieve CO2-neutral transportation in cities. In our proposed system, electricity generated from widely introduced solar photovoltaic panels

著者

Thomas BRUDERMANN Romana RAUTER Yoshiki YAMAGATA

出版者

ISCM Forum

雑誌

Innovation and Supply Chain Management (ISSN:21870969)

巻号頁・発行日

vol.7, no.3, pp.83, 2013-09-30 (Released:2014-04-02)

参考文献数

63

被引用文献数

1 4

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The current discussion on urban resilience is dominated by infrastructural and technological considerations. Although behavioral reactions to extreme events very well impact the overall resilience of urban systems, they are not very well considered. In order to close this gap, we review relevant insights on human decision making and collective dynamics, and propose a framework for studying behavioral aspects in the context of urban resilience. We findthat human decision making is often based on simple ‘heuristics'. Especially in emergency situations, e.g. during or in the aftermath of extreme events, simple decision making rules replace careful and rational assessment of different choice alternatives. However, collective reactions to extreme events are note only dependent on individual decisions, but are shaped by complex interactions of various system elements, including the natural and manmade environment, people's interactions with the environment, and people's interactions with each other. For a proper anticipation of possible collective reactions and their impact on urban systems, we suggest agent-based simulations which utilize decision making insights and interaction data gathered in experiments and in the field. The current discussion on urban resilience is dominated by infrastructural and technological considerations.

著者

Mohammadreza PARSANEJAD Hiroaki MATSUKAWA Tomoichi SATO

出版者

ISCM Forum

雑誌

Innovation and Supply Chain Management (ISSN:21870969)

巻号頁・発行日

vol.7, no.2, pp.66-74, 2013-06-30 (Released:2014-04-02)

参考文献数

13

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Measuring project success is a challenging issue among researchers and practitioners, because of its multidimensional properties. During the last three decades, numerous researchers have tried to define and illustrate its dimensions. But still there is no general agreement about it. To measure and predict success of a project, we need to take into account all project stages including utilization stage of the product of a project in an integrated approach. In this paper we try to introduce a novel model to measure project success considering selection, execution and utilization stages. The model is based on the deviations from the goal of each stages. And the amount of success in this model which we call the “Circles Model”, is the magnitude of proximity to the final goal. We apply it to an example and measure its success quantitatively. Lastly we discuss four extensible directions for future studies to apply the model on high performance projects, multi stakeholders space, program and portfolio domain and finally to explore the inŽuence of the performance of each stage on the performance of the next stages.

著者

Yasuhiko TAKEMOTO Ikuo ARIZONO

出版者

ISCM Forum

雑誌

Innovation and Supply Chain Management (ISSN:21870969)

巻号頁・発行日

vol.7, no.2, pp.52-57, 2013-06-30 (Released:2014-04-02)

参考文献数

11

被引用文献数

2 5

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In Japan, books and magazines have been distributed under the resale price maintenance and consignment sale systems. At present, the return rate of books and magazines has reached approximately 40 percent of the quantity of publications under the systems mentioned above. This is a severe problem from the viewpoints of both business and environment. For the purpose to solve this problem, a new sale system where wholesale price is reasonable while buyback price is inexpensive has been programmed and practiced. The wholesale and buyback prices are important contract parameters in the transaction program between publisher and bookstore. In this paper, the publishing supply chain consisting of a publisher and a bookstore is formulated as a mathematical model. Then, we have developed a new approach to solve the collaborative sale contract problem with wholesale and buyback prices as contract parameters.

著者

Yue WU Hongyu LI Jinsheng YANG Liming ZHENG

出版者

ISCM Forum

雑誌

Innovation and Supply Chain Management (ISSN:21870969)

巻号頁・発行日

vol.7, no.2, pp.39-45, 2013-06-30 (Released:2014-04-02)

参考文献数

26

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This study discusses management principles which provides computational aid to management including monitoring, analysis and navigation of knowledge creators activities. Firstly, it attempts to identify two management principles based on the Ontological Shift Model, and give three indicators to diagnosis knowledge creation projects.

著者

Fatema Tuj Zohra Yoshie Maitani Toshihiro Akaike

出版者

公益社団法人日本薬学会

雑誌

Biological and Pharmaceutical Bulletin (ISSN:09186158)

巻号頁・発行日

vol.35, no.1, pp.111-115, 2012-01-01 (Released:2012-01-05)

参考文献数

35

被引用文献数

2 16

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It was believed for a long time that mRNA is very unstable, and can not be used for therapeutic purposes. In the last decade, however, many research groups proved its transfection feasibility along with advantages and applications. Our investigation is aimed at establishing a potent and efficient mRNA delivery system. We previously reported that an inorganic–organic hybrid carrier by exploiting the advantages of inorganic nano apatite particles onto organic carrier DOTAP {N-[1-(2,3-dioleoloxy)propyl]-N,N,N-trimethyl ammonium chloride} and showed potential effect of carbonate apatite particles on each of the mRNA delivery steps in dividing and non-dividing cell. Here, we report on the development of a more efficient mRNA carrier by complexing ECM protein, fibronectin with the DOTAP-apatite carrier. The carrier showed enhanced uptake of luciferase mRNA both qualitatively and quantitatively. Accelerated cellular endocytosis rate was evaluated using labeled endosome. Finally expression of lucifearse mRNA was higher for fibronectin complexed carrier in compared to the uncoated one.

著者

前田 七瀬 猿丸 朋久 木嶋 晶子 吉田 直美 西野 洋 片岡 葉子

出版者

日本皮膚科学会大阪地方会・日本皮膚科学会京滋地方会

雑誌

皮膚の科学 (ISSN:13471813)

巻号頁・発行日

vol.8, no.Suppl.12, pp.B707-B712, 2009 (Released:2012-04-18)

参考文献数

3

被引用文献数

1

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13歳,男児。幼少時より重症アトピー性皮膚炎(AD)にて加療していたが,9才時,アスペルガー障害,発達障害と診断された。その後も両親の離婚や母親が精神状態不安定であり,スキンケアが十分に行えず,入退院を繰り返していた。経過中にパニックを発症し,自己欲求が満たされない際・他人と衝突した際などに,周囲への暴力行為・自傷行為に至り,精神的に非常に不安定となった。児童精神科医からパニック時の対処法の指導を受け,併診しながら加療を続けた。我々の本人への対応として,(1)パニック時は周囲に害が及ばないように配慮した。(2)話を傾聴し,支持した。(3)努力を誉めることを重視した。(4)不適切な行動は明瞭に指摘し,指導を行った。(5)理解しやすいように,あいまいな表現にならないように努めた。ADの治療に関しては,ステロイド外用指導には,図を用いてわかりやすく説明した。頻回に通院し,治療へのモチベーションをあげるようにした。この対応により,徐々に精神的に安定したことで,パニックを起こさないようになり,皮膚症状も軽快した。精神的な状態によって,ストレスによる掻破やセルフコントロールの不備が生じ,皮膚症状が大きく左右されるため,精神面の安定および適切な適応のサポートは,本児の日常生活のみでなく,皮膚炎を改善させる上でも非常に重要な因子であった。成長と共に生じた問題とその対応について報告する。

著者

青井 貴之

出版者

一般社団法人 日本臨床薬理学会

雑誌

臨床薬理 (ISSN:03881601)

巻号頁・発行日

vol.42, no.3, pp.141-142, 2011 (Released:2011-10-03)

著者

青木 健一

出版者

公益社団法人 東京地学協会

雑誌

地学雑誌 (ISSN:0022135X)

巻号頁・発行日

vol.111, no.6, pp.849-855, 2002-12-25 (Released:2009-11-12)

参考文献数

30

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Aspects of cultural transmission in humans are reviewed with special reference to evidence for and against vertical (parent-to-child) and non-vertical transmission. Henrich's (2001) model of biased horizontal transmission may satisfactorily account for the S-shaped adoption curves (e.g., for the spread of hybrid seed corn). The demic expansion hypothesis for the spread of early farming in Europe (Ammerman and Cavalli-Sforza, 1971, 1973) is reevaluated in the light of new theoretical results (Aoki et al., 1996). Hewlett et al.'s (2002) test of the demic expansion, acculturation, and cultural-materialistic hypotheses on 36 African ethnic groups is described.

著者

鮫島 一平 加賀美 聡 溝口 博 河内 まき子

出版者

一般社団法人 日本ロボット学会

雑誌

日本ロボット学会誌 (ISSN:02891824)

巻号頁・発行日

vol.31, no.8, pp.761-768, 2013 (Released:2013-11-15)

参考文献数

9

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This paper describes a method to estimate a set of body dimensions of a subject using the Microsoft Kinect sensor. Principal Component Analysis(PCA) of the AIST anthropometric database shows principal components are interpreted as scale, degree of obesity, length of the upper body, size of the thigh and size of the buttocks respectively. A few body dimensions were chosen by linear multiple regression analysis. Applying the resulting estimator to a given subject using the Kinect sensor to obtain joint positions and 5 body dimensions by analyzing depth image, we can estimate a set of body dimensions for the subject. The system is described and experimental results are shown.

著者

Zeyad El-Akawi Nisreen Abdel-Latif Khalid Abdul-Razzak Mustafa Al-Aboosi

出版者

公益社団法人 日本薬学会

雑誌

Journal of Health Science (ISSN:13449702)

巻号頁・発行日

vol.53, no.5, pp.596-599, 2007 (Released:2007-10-01)

参考文献数

5

被引用文献数

4 20

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Minimal reports are available on the relationship between blood lipids such as cholesterol, triglycerides, high-density lipoprotein cholesterol (HDL-C) and low density lipoprotein cholesterol (LDL-C) and acne. Most of available literature was about the effect of drugs used in acne treatment on these parameters. In this work we determined plasma total cholesterol, triglycerides, HDL-C and LDL-C levels in 166 (83 males and 83 females) newly diagnosed untreated Jordanian acne patients and compared with 105 (52 males and 53 females) of age and sex matched healthy controls. Results indicated that acne patients, males and females, had significantly low plasma HDL-C levels (p=0.000). Plasma total cholesterol, triglycerides and LDL-C levels were shown to be within the normal range except for triglycerides and LDL-C levels in severe acne cases for both sexes, were shown to be significantly elevated compared with those in healthy controls (p=0.004 and 0.000 consequently). It has been noticed that there was a trend for plasma HDL-C of acne patients to decrease as the severity of acne condition increases. Our results indicated that acne patients have significant changes in the plasma lipids profile that should be considered in the pathogenesis as well as in the treatment of acne.

著者

佐藤 俊 渡邉 香奈 石田 卓 吉川 素子 金沢 賢也 斎藤 純平 大塚 義紀 棟方 充 鈴木 均 丸山 幸夫

出版者

一般社団法人 日本内科学会

雑誌

日本内科学会雑誌 (ISSN:00215384)

巻号頁・発行日

vol.95, no.2, pp.356-358, 2006-02-10 (Released:2009-03-27)

参考文献数

7

被引用文献数

1 2

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症例は47歳, 男性. 拡張型心筋症による発作性心房粗動に対しアミオダロンの投与を開始, 2年後に胸部X線写真にて異常陰影が出現. 肺胞洗浄, 肺生検所見などから総合的にアミオダロンによる薬剤性肺炎と診断した. 短期間のステロイド治療が奏功し, 現在まで再燃は認めない. 本症では肺胞洗浄液にて好酸球の著増を認め, 細胞毒性による肺障害と免疫学的機序を背景とした好酸球性肺炎の併発が考えられた.

著者

米山 桂三

出版者

日本社会学会

雑誌

社会学評論 (ISSN:00215414)

巻号頁・発行日

vol.2, no.3, pp.18-27, 1952-01-10 (Released:2009-11-11)