著者

尾鍋 史彦

出版者

社団法人 繊維学会

雑誌

繊維学会誌 (ISSN:00379875)

巻号頁・発行日

vol.56, no.6, pp.P_166-P_169, 2000 (Released:2001-10-31)

参考文献数

3

著者

谷村 晋

出版者

ITヘルスケア学会

雑誌

ITヘルスケア誌 (ISSN:18814808)

巻号頁・発行日

vol.1, no.1, pp.30-39, 2006-09-25 (Released:2007-01-18)

参考文献数

12

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学会プレゼンテーションの映写機器をコンピュータと液晶プロジェクタに切り替える学会が一般化してきたが、このときMicrosoft PowerPointが排他的に指定される傾向にある。学会プレゼンテーションに必要なソフトウェアの条件項目を多角的に検討した結果、PowerPointは学会プレゼンテーションのための映写ソフトウェアとして、むしろ不適切であることを明らかにした。必要とされる条件項目を満たす代替手法として、本稿ではPDFファイルによるプレゼンテーション(PDFプレゼンテーション)を提案するとともに、その具体的な例と留意点を示す。PDFプレゼンテーションを採用すると、学会運営側はPowerPointの場合よりも低費用低リスクで安心でき、発表者側はスライド作成負担が軽減される。

著者

Takashi NAITO Yuriko SAKATA

出版者

Psychologia Society

雑誌

PSYCHOLOGIA (ISSN:00332852)

巻号頁・発行日

vol.53, no.3, pp.179-194, 2010 (Released:2010-11-03)

参考文献数

33

被引用文献数

11 39

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To explore different functions of gratitude and indebtedness, two questionnaire studies were conducted with female university students in Japan. These studies examined the correlations between positive feelings, regret, and indebtedness when receiving a favor, and the resulting feelings such as the enhancement of prosocial motivation (wish to help) and the obligation to help others. The results of Study 1 suggested that positive feelings and indebtedness in a hypothetical helping situation differently correlated with other variables: Positive feelings had a significant positive correlation with the enhancement of prosocial motivation. In contrast, indebtedness had a significant positive correlation with enhancement of obligation (should help). Study 2 was conducted by using positive and socially conceptualized feeling items such as the fulfillment of friendship. Results suggested that the social conceptualization might add obligatory nature to the positive feelings.

著者

Masago Ishikawa Ichiro Kawase Fumio Ishii

出版者

The Pharmaceutical Society of Japan

雑誌

Biological and Pharmaceutical Bulletin (ISSN:09186158)

巻号頁・発行日

vol.30, no.11, pp.2031-2036, 2007-11-01 (Released:2007-11-01)

参考文献数

37

被引用文献数

12 16

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The simplest amino acid, glycine, is important in protein composition and plays a significant role in numerous physiological events in mammals. Despite the inhibitory effect of glycine on spontaneous melanogenesis in B16F0 melanoma cells, the details of the underlying mechanisms remain unknown. The present study was conducted to investigate the further effects and the mechanisms of inhibitory effect of glycine on melanogenesis using B16F0 melanoma cells and hair follicle melanogenesis in C57BL/6J mice. Treatment with glycine (1—16 mM) for 72 h inhibited α-melanocyte stimulating hormone (α-MSH)-induced melanogenesis in a concentration-dependent manner without any effects on cell proliferation in B16F0 melanoma cells. Treatment with kojic acid (2.5 mM) for 72 h also inhibited α-MSH-induced melanogenesis in B16F0 melanoma cells. The highest dose of glycine inhibited the α-MSH-induced increment of tyrosinase protein levels in B16F0 melanoma cells. In hair follicle melanogenesis in C57BL/6J mice, treatment with glycine (1250 or 2500 mg/kg, i.p.) for 5 d prevented the decrement of L* and C* values and inhibited the increment of tyrosinase protein levels and melanin content within the skin. Treatment with hydroquinone (100 mg/kg, i.p.) for 5 d had a similar hypopigmenting effect to that of high dose glycine. These results suggest that glycine has an inhibitory effect on melanogenesis that is mediated by down-regulation of tyrosinase protein levels, leading to a hypopigmenting effect in C57BL/6J mice.

著者

江原 学

出版者

一般社団法人 映像情報メディア学会

雑誌

映像情報メディア学会誌 (ISSN:13426907)

巻号頁・発行日

vol.61, no.11, pp.1567-1570, 2007-11-01 (Released:2010-01-15)

被引用文献数

5 4

著者

川口 泰雄

出版者

日本神経回路学会

雑誌

日本神経回路学会誌 (ISSN:1340766X)

巻号頁・発行日

vol.5, no.4, pp.171-177, 1998-12-05 (Released:2011-01-17)

参考文献数

40

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To understand the inhibitory network in the cortex, we have started to clarify several features of GABAergic neurons in the frontal cortex of rats. These are; (1) the physiological, chemical and morphological characteristics of cortical GABAergic neurons to identify the subtypes, (2) the synaptic connections among these neuronal subtypes and (3) the synaptic properties and the chemical modulation of each subtype. An experimental approach in which multiple properties of a GABA neuron are determined for the same cell, yields a set of data which allows a more comprehensive classification of the neuron as an element of a local neuronal circuit.

著者

八木 哲也 高見 涼太郎

出版者

日本神経回路学会

雑誌

日本神経回路学会誌 (ISSN:1340766X)

巻号頁・発行日

vol.6, no.3, pp.167-171, 1999-09-05 (Released:2011-01-17)

参考文献数

13

被引用文献数

1 1

著者

横山 絵里子 中野 明子

出版者

一般社団法人 日本脳卒中学会

雑誌

脳卒中 (ISSN:09120726)

巻号頁・発行日

vol.32, no.6, pp.634-640, 2010-11-26 (Released:2010-12-03)

参考文献数

24

被引用文献数

6

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【目的】脳卒中の栄養状態と認知・運動機能,ADLとの関連を明らかにする.【方法】対象は慢性期脳卒中381例(平均68±11歳)で,下肢運動年齢(MA),Barthel index(BI),改訂長谷川式簡易知能評価スケール(HDS),Functional Independence Measure(FIM),長谷川式簡易知的機能評価スケール(HDS),標準失語症検査(SLTA),行動性無視検査(BIT)の評価と同時期にbody mass index(BMI),血清アルブミン(Alb),体重変化率を指標に栄養状態を評価した.【結果】栄養状態は全体の69%が低栄養であった.高度な低栄養ほどMA,BI,FIM,HDS,SLTA,BITは低下していた.順位相関係数の検討ではMA,BI,HDS,SLTAはBMIやAlbと有意な正の相関を認めた.【結論】低栄養が認知・運動機能やADL低下に関与する可能性が示された.

著者

Masago Ishikawa Ichiro Kawase Fumio Ishii

出版者

The Pharmaceutical Society of Japan

雑誌

Biological and Pharmaceutical Bulletin (ISSN:09186158)

巻号頁・発行日

vol.30, no.4, pp.677-681, 2007 (Released:2007-04-01)

参考文献数

34

被引用文献数

18 23

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Amino acids, the building blocks of proteins, play significant roles in numerous physiological events in mammals. As the effects of amino acids on melanogenesis have yet to be demonstrated, the present study was conducted to identify whether amino acids, in particular alanine, glycine, isoleucine and leucine, influence melanogenesis in B16F0 melanoma cells. Glycine and L-isoleucine, but not D-isoleucine, reduced melanogenesis in a concentration-dependent manner without any morphological changes in B16F0 melanoma cells. L-Alanine and L-leucine, but not D-alanine and D-leucine, also reduced melanogenesis without any morphological changes in B16F0 melanoma cells. However these amino acids did not show a concentration-dependency. Combination of L-alanine and the other amino acids, particularly 4 amino acids combination, had an additive effect on the inhibition of melanogenesis compared with single treatment of L-alanine. None of the amino acids affected the activity of tyrosinase, a key enzyme in melanogenesis. These results suggest that L-alanine, glycine, L-isoleucine and L-leucine, but not the D-form amino acids, have a hypopigmenting effect in B16F0 melanoma cells, and that these effects are not due to the inhibition of tyrosinase activity. Combination of these 4 amino acids had the additive effect on hypopigmentation that was as similar as that of kojic acid.

著者

小林 由佳 山田 美佐 藤井 裕美 甲 由紀子 魚谷 いづみ 田本 真理子 名田 正子 村井 裕之 角 英 岩垣 博巳 友田 純 斎藤 信也

出版者

岡山医学会

雑誌

岡山医学会雑誌 (ISSN:00301558)

巻号頁・発行日

vol.122, no.3, pp.225-229, 2010-12-01 (Released:2011-01-04)

参考文献数

17

被引用文献数

1

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To evaluate the usefulness of the waterless hand washing method for surgical anti-sepsis, we conducted a microbial sampling study, comparing it to a conventional surgical scrub method. A total of 18 operating-room nurses were undertaking the following three-hand washing protocols : scrubbing with blushes using 4w/v% chlorhexidine gluconate (CHG) and also rubbing with CHG, followed by application of a 0.2w/v% CHG with ethanol (HS) preparation. (conventional method); rubbing with CHG and application of HS (two-stage surgical scrub method; TSS); rubbing with anti-septic soap and application of HS (waterless method; WL). Microbial sampling was conducted after hand washing using the glove juice method. No statistically significant differences in bacterial numbers were found among these three methods. The number of bacterially positive subjects was significantly higher in the conventional method than the TSS method. These results indicate that there are adverse effects of blush-scrubbing, as the detected bacteria were related to normal skin flora. As such, the WL method for hand anti-sepsis appears to be equivalent to the conventional surgical scrubbing method in terms of microbial detection. The WL method should therefore be introduced as a standard hand anti-sepsis method at the time of surgery because it is cost-effective as well as time-efficient.

著者

藤井 正博 早坂 康隆 堀江 憲路

出版者

一般社団法人 日本地質学会

雑誌

地質学雑誌 (ISSN:00167630)

巻号頁・発行日

vol.114, no.3, pp.127-140, 2008-03-15 (Released:2009-02-24)

参考文献数

48

被引用文献数

5 9

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九州東部野津原地域の基盤岩類は,高温低圧型変成岩からなる朝海ユニットの上位に,蛇紋岩からなる超苦鉄質岩ユニットを介し,非変成砕屑岩類からなる日方ユニットが重なるナップ構造で特徴づけられる.朝海ユニットの変成分帯,および黒雲母とザクロ石の化学組成から,朝海ユニットの変成作用は,荷尾杵花崗岩の貫入による接触変成作用であることが明らかとなった.その変成条件は荷尾杵花崗岩近傍で約610℃,2 kbarと見積もられる.また,荷尾杵花崗岩のジルコンのSHRIMP U-Pb年代は134.7±2.8 Ma(2σ)を示す.日方ユニットは朝海ユニットにおける荷尾杵花崗岩の接触変成作用による熱構造を切っていること,また,上部白亜系大野川層群に不整合に覆われることから,ナップ運動は荷尾杵花崗岩の貫入(約135 Ma)以降,大野川層群の堆積開始前(セノマニアン: 約100 Ma)の期間に生じたと考えられる.

著者

Eiko Mieda Takahiro Sasamori Shohei Sase Kei Goto Norihiro Tokitoh

出版者

The Chemical Society of Japan

雑誌

Chemistry Letters (ISSN:03667022)

巻号頁・発行日

vol.40, no.2, pp.196-197, 2011-02-05 (Released:2011-01-22)

参考文献数

18

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We report here the attempted synthesis of a stable 1-fluoro-2-hydrosilene bearing a Bpq group, which is a bulky aryl group bearing a cavity-shaped framework. We have successfully synthesized an overcrowded benzyldifluorosilane as a precursor. Treatment of the benzyldifluorosilane with 2 equiv of t-BuOK in THF afforded the corresponding benzyl anion, the structure of which showed a unique feature as a fluorosilene–KF complex.

著者

Kazuyuki HIWATASHI Yasuyuki KOSAKA Nao SUZUKI Keishi HATA Toshiyuki MUKAIYAMA Kenji SAKAMOTO Hitoshi SHIRAKAWA Michio KOMAI

出版者

Japan Society for Bioscience, Biotechnology, and Agrochemistry

雑誌

Bioscience, Biotechnology, and Biochemistry (ISSN:09168451)

巻号頁・発行日

vol.74, no.7, pp.1447-1451, 2010-07-23 (Released:2010-07-23)

参考文献数

20

被引用文献数

42

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The effects of dietary Yamabushitake mushroom (Hericium erinaceus) on lipid metabolism were examined. C57BL/6J mice were fed a high-fat diet containing hot-water extract (HW-E) and an ethanol extract (EtOH-E) of Yamabushitake mushroom. Administration of HW-E or EtOH-E with a high-fat diet for 28 d resulted in a significant decrease in body weight gain, fat weight, and serum and hepatic triacylglycerol levels. Our in vitro experiments indicated that EtOH-E acts as an agonist of peroxisome proliferator-activated receptor α (PPARα). Quantitative analyses of hepatic mRNA levels revealed that EtOH-E administration resulted in up-regulation of mRNA for a number of PPARα-regulating genes in spite of the fact that the gene expression of PPARα did not change. These results suggest that EtOH-E improves lipid metabolism in mice fed a high-fat diet, and that these effects were mediated by modulation of lipid metabolic gene expression, at least in part via activation of PPARα.

著者

堤 拓哉 高橋 章弘 南 慎一 植松 康

出版者

一般社団法人 日本風工学会

雑誌

日本風工学会論文集 (ISSN:13493507)

巻号頁・発行日

vol.34, no.3, pp.75-83, 2009-07-01 (Released:2009-10-17)

参考文献数

10

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A tornado struck Wakasa Region of Saroma Town in Hokkaido on November 7, 2006. The tornado killed nine people and injured more than 30 people. Many buildings were collapsed or damaged by this tornado. The authors made a damage investigation just after the disaster. This paper presents the characteristics of the damage. It was found that completely and partially destroyed houses were all located along the track of the tornado. The roofs were flown off and walls and windows were broken by flying debris. The aspects of the building damage are closely related to the materials and method of construction typical of snowy cold regions.

著者

清水 浩

出版者

日本ばね学会

雑誌

ばね論文集 (ISSN:03856917)

巻号頁・発行日

vol.2008, no.53, pp.81-86, 2008-05-07 (Released:2008-11-01)

著者

浅野 優 田中 譲

出版者

一般社団法人 人工知能学会

雑誌

人工知能学会論文誌 (ISSN:13460714)

巻号頁・発行日

vol.26, no.1, pp.248-261, 2011 (Released:2011-01-06)

参考文献数

16

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This paper describes a new framework for querying the Semantic Web using a rich vocabulary. This framework consists of two mechanisms; one for building a rich vocabulary based on lexicographic semantics, and the other for evaluating queries using such a vocabulary. A vocabulary built by the former mechanism has the following two features: (a) its richness because of its expandability and (b) the lexicographic-semantic definition of its words. Query expressions using such a rich vocabulary satisfy the following two properties: (c) no need to use nested query structures, and (d) no need to use variables. In our framework, a new word, i.e., a derived word, can be defined as a character string label given to an expression that combines already defined words with operators. This expression, or phrase, works as a lexicographic definition of this derived word. Each vocabulary consists of basic words and derived words. A lexicon of a vocabulary denotes a set of lexicographic definitions of all of its derived words. Once someone defines a lexicon of a large vocabulary with all of its basic words being mapped to an ontology of the Semantic Web, users can query this Semantic Web using this vocabulary. The same lexicon can be reused for the Semantic Web that has a different ontology if all of its basic words are newly mapped to its ontology. Use of a rich vocabulary in querying a Semantic Web simplifies the query sentence structure and removes the necessity of using variables from each query, which makes it much easier for users to query the Semantic Web. This framework provides query evaluation rules based on the proposed lexicographic semantics, which guarantees that each query using such a rich vocabulary is correctly evaluated over the underlying Semantic Web.

著者

中澤 理恵 坂本 雅昭 草間 洋一

出版者

理学療法科学学会

雑誌

理学療法科学 (ISSN:13411667)

巻号頁・発行日

vol.22, no.1, pp.119-123, 2007 (Released:2007-04-10)

参考文献数

21

被引用文献数

7 3

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本研究の目的は,中学生サッカー選手における身長成長速度曲線の成長区分(phase)と下肢筋の柔軟性との関係について検討することである。対象は中学生男子サッカー部員107名とし,傷害の有無や身長成長速度,下肢筋柔軟性について調査・測定した。その結果,体幹・下肢に傷害のない70名のphaseの内訳は,phase I 4名(phase I群),phase II 28名(phase II群),phase III 38名(phase III群)であった。また,phase II群およびphase III群間で下肢筋柔軟性を比較した結果,phase III群の右腸腰筋,左大腿四頭筋,右ハムストリングス,左下腿三頭筋が有意に低下していた。これは,身長の成長促進現象に伴う骨および筋・腱の成長の不均衡の長期的な蓄積およびサッカーの競技特性のひとつであるキック動作が影響を及ぼしたものと考える。今後,縦断的に身長成長速度曲線と筋柔軟性の関係を検討していくことの必要性が示され,成長期スポーツ障害予防への関与の可能性が示唆された。

著者

Izumi Iwakura Atushi Yabushita Takayoshi Kobayashi

出版者

The Chemical Society of Japan

雑誌

Chemistry Letters (ISSN:03667022)

巻号頁・発行日

vol.39, no.4, pp.374-375, 2010-04-05 (Released:2010-03-06)

参考文献数

34

被引用文献数

28

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The detailed processes in the Claisen rearrangement were observed. The process was vibrationally excited in the electronic ground state by a stimulated Raman process using a 5-fs pulse. The Claisen rearrangement was found to follow a three-step pathway. At first, the C4–O bond is weakened to generate a bis-allyl-like intermediate. Next, the formation of a weak C1–C6 bond results in the generation of an aromatic-like intermediate. Finally, C4–O breaking and C1–C6 formation occur simultaneously to generate the product.

著者

Eun-Joo Shin Phil Ho Lee Hyun Ji Kim Toshitaka Nabeshima Hyoung-Chun Kim

出版者

The Japanese Pharmacological Society

雑誌

Journal of Pharmacological Sciences (ISSN:13478613)

巻号頁・発行日

vol.106, no.1, pp.22-27, 2008 (Released:2008-01-22)

参考文献数

42

被引用文献数

15 16

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Drug abuse involving dextromethorphan, an antitussive, has been a social problem in various geographic locations since the 1960s. Ironically, high doses of the drug confer neuroprotective activity with central nervous system and behavioral effects. Accumulating evidence suggests that metabolism to phencyclidine-like dextrorphan is not essential for the neuroprotective activity of dextromethorphan. Here, we review the neuroprotective properties of dextromethorphan and its potential for abuse and the potential neuroprotective effects of the drug’s analogs and 3-hydroxymorphinan, a metabolite of dextromethorphan. These compounds may provide a novel therapeutic direction for the treatment of neurodegenerative diseases such as convulsive or parkinsonian-like disorders.

著者

堀田 昌英 榎戸 輝揚 岩橋 伸卓

出版者

社会技術研究会

雑誌

社会技術研究論文集 (ISSN:13490184)

巻号頁・発行日

vol.1, pp.67-76, 2003 (Released:2009-08-19)

参考文献数

16

被引用文献数

4 4

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本論文は多元主義的アプローチに基づいた政策論議の構造化手法を提案する. 議論の論理的及び言語学的構造を視覚的に表すことで議論の支援を行うシステムはこれまでも社会問題に適用されてきた. しかし議論支援システムを複雑な社会問題の理解に役立てるためには, 互いに対立する事実認識や価値観を抽出し, それらが同時に説得的であり得るような議論を既存の情報から再構築することが必要になる. 本研究で提案する手法は, 多数の議論や情報資源の中から特に複雑でかつ注目に値する一連の議論を抽出するための指針を与えるものである. 本手法は情報システムとして実用化され, 公共的な議論の支援に適用された. 本論文では事例研究の結果と社会技術システム論への含意について述べる.