著者

Akiyoshi TANI Hirotaka TOMIYASU Hajime ASADA Chen-Si LIN Yuko GOTO-KOSHINO Koichi OHNO Hajime TSUJIMOTO

出版者

JAPANESE SOCIETY OF VETERINARY SCIENCE

雑誌

Journal of Veterinary Medical Science (ISSN:09167250)

巻号頁・発行日

pp.21-0506, (Released:2022-04-06)

被引用文献数

3

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Interactions between tumor and immune cells within the tumor microenvironment play an important role in tumor progression, and small extracellular vesicles (EVs) derived from these tumor cells have been shown to exert immunomodulatory effects on various immune cells, including macrophages and lymphocytes. Although the immunomodulatory effects of small EVs derived from human cancer cells have been intensively investigated, few studies have investigated the effects of lymphoma-derived small EVs on macrophages in both human and veterinary medicine. Here, we evaluated the effects of canine lymphoma-derived small EVs on canine primary monocytes, which are the major source of macrophages in neoplastic tissues. Comprehensive gene expression analysis of these treated monocytes revealed their distinct activation via the Toll-like receptor (TLR) and NF-κβ signaling pathways. In addition, treatment with lymphoma small EVs increased the secretion of MCP-1, which induces the infiltration and migration of monocytes and lymphocytes in neoplastic and cancer tissues. The results of this study indicate that canine lymphoma small EVs activate monocytes, possibly through the activation of TLR and NF-κβ signaling pathways, and induce monocytes to secrete of MCP-1, which might contribute to immune cell infiltration within the tumor microenvironment.

著者

Daisuke Sueta Eiichiro Yamamoto Hiroki Usuku Satoru Suzuki Taishi Nakamura Kunihiko Matsui Takaaki Akasaka Kazuhito Shiosakai Kotaro Sugimoto Kenichi Tsujita on behalf of the ESES-LVH Study Investigators

出版者

The Japanese Circulation Society

雑誌

Circulation Reports (ISSN:24340790)

巻号頁・発行日

vol.4, no.2, pp.99-104, 2022-02-10 (Released:2022-02-10)

参考文献数

16

被引用文献数

2

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Background:The complication of left ventricular (LV) hypertrophy (LVH) is associated with increased incidence of major cardiovascular events. Hypertension is an independent risk factor among several factors contributing to the development of LVH, and thus appropriate treatment of both hypertension and LVH reduces the risk of developing heart failure. Mineralocorticoid-receptor blockers (MRBs) have been reported to improve the prognosis of LVH, but use of currently available MRBs is limited by adverse events. Esaxerenone is a novel selective nonsteroidal MRB recently approved for treatment of hypertension. Although the renoprotective effect of esaxerenone has been demonstrated in both preclinical and clinical studies, little data is available in terms of its cardioprotective effects.Methods and Results:This multicenter, open-label, exploratory interventional study was designed to evaluate the safety and efficacy of esaxerenone in combination with renin-angiotensin system (RAS) inhibitors or calcium-channel blockers (CCBs). Eligible criteria are hypertensive patients with LVH, and target blood pressure (BP) not reached with an RAS inhibitor or a CCB. The primary endpoints are change from baseline in seated home BP (early morning systolic/diastolic BPs), and change and %change from baseline in the LV mass index at the end of treatment.Conclusions:This study will provide the first clinical evidence of the antihypertensive effect and safety of esaxerenone in hypertensive patients with LVH.

著者

Charley-Lea POLLARD Ashleigh YOUNAN Aleona SWEGEN Zamira GIBB Christopher G. GRUPEN

出版者

The Society for Reproduction and Development

雑誌

Journal of Reproduction and Development (ISSN:09168818)

巻号頁・発行日

pp.2021-130, (Released:2022-03-28)

被引用文献数

8

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Treatments that elevate NAD+ levels have been found to improve oocyte quality in mice, cattle, and pigs, suggesting that NAD+ is vital during oocyte maturation. This study aimed to examine the influence of different NAD+ biosynthetic pathways on oocyte quality by inhibiting key enzymes. Porcine oocytes from small antral follicles were matured for 44 h in a defined maturation system supplemented with 2-hydroxynicotinic acid (2-HNA, nicotinic acid phosphoribosyltransferase; NAPRT inhibitor), FK866 (nicotinamide phosphoribosyltransferase; NAMPT inhibitor), or gallotannin (nicotinamide mononucleotide adenylyltransferase; NMNAT inhibitor) and their respective NAD+ pathway modulators (nicotinic acid, nicotinamide, and nicotinamide mononucleotide, respectively). Cumulus expansion was assessed after 22 hr of maturation. At 44 h, maturation rates were determined and mature oocytes were fixed and stained to assess spindle formation. Each enzyme inhibitor reduced oocyte maturation rate and adversely affected spindle formation, indicating that NAD+ is required for meiotic spindle assembly. Furthermore, NAMPT and NMNAT inhibition reduced cumulus expansion, whereas NAPRT inhibition affected chromosomal segregation. Treating oocytes with NAD+ pathway inhibitors in combination with nicotinamide mononucleotide or nicotinic acid improved spindle parameters compared with the inhibitors alone. These results indicate that the salvage pathway plays a vital role in promoting oocyte meiotic progression, while the Preiss-Handler pathway is essential for spindle assembly.

著者

Yeon Sil Lee Young-Hee Kang Ju-Young Jung Sanghyun Lee Kazuo Ohuchi Kuk Hyun Shin Il-Jun Kang Jung Han Yoon Park Hyun-Kyung Shin Soon Sung Lim

出版者

The Pharmaceutical Society of Japan

雑誌

Biological and Pharmaceutical Bulletin (ISSN:09186158)

巻号頁・発行日

vol.31, no.10, pp.1968-1972, 2008-10-01 (Released:2008-10-01)

参考文献数

37

被引用文献数

23 59

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To characterize active principles for prevention and treatment of diabetic complications, the isolation of protein glycation inhibitors from the fruiting body of Phellinus linteus was conducted in vitro using the model systems of hemoglobin-δ-gluconolactone (early stage), bovine serum albumin-methylglyoxal (middle stage), and Nα-acetyl-glycyl-lysine methyl ester-D-ribose (last stage) assays. Nine compounds were isolated from the active ethylacetate fraction of the fruiting body and identified as protocatechuic acid (1), protocatechualdehyde (2), caffeic acid (3), ellagic acid (4), hispidin (5), davallialactone (6), hypholomine B (7), interfungins A (8), and inoscavin A (9) by spectroscopic analyses. At the early stage of protein glycation, compounds 6, 8, and 9 exhibited inhibitory activity on hemoglobin A1C formation. For the middle stage, compounds 2, 6, and 9 showed a significant inhibitory effect on methylglyoxal-medicated protein modification and their IC50 values were 144.28, 213.15, and 158.66 μM, respectively. At the last stage of glycation, compound 8 was found to be a potent inhibitor of the cross-linking of proteins, which was more effective than that of aminoguanidine, a well-known inhibitor for advanced glycation end products. Consequently, compound 8 showed the most potent inhibitory effects at each stage of protein glycation. This mechanism may help to provide a protective effect against hyperglycemia-mediated protein damage.

著者

Phoon Wai-On ONG Choon Nam FOO Swee Cheng PLUEKSAWAN Wisai

出版者

公益社団法人日本産業衛生学会

雑誌

産業医学 (ISSN:00471879)

巻号頁・発行日

vol.25, no.6, pp.463-470, 1983-11-20

著者

Koutatsu Maruyama Saori Miyazaki Satomi Minato-Inokawa

出版者

Japan Atherosclerosis Society

雑誌

Journal of Atherosclerosis and Thrombosis (ISSN:13403478)

巻号頁・発行日

vol.29, no.2, pp.141-142, 2022-02-01 (Released:2022-02-01)

参考文献数

10

被引用文献数

1

著者

LIU Ying Lung TAM Chi-Yung AU-YEUNG Andie Yee Man

出版者

Meteorological Society of Japan

雑誌

気象集誌. 第2輯 (ISSN:00261165)

巻号頁・発行日

pp.2022-008, (Released:2021-10-26)

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The role of extratropical forcing on the summertime tropical synoptic-scale disturbances (TSDs) in the western north Pacific has been investigated, by conducting parallel integrations of the Regional Climate Model (RegCM). The suite of experiments consists of a control run (CTRL) with European Centre for Medium Range Forecasts (ECMWF) Reanalysis data as boundary conditions, and an experimental run (EXPT) with the same setting, except that signals with zonal wavenumber > 6 were suppressed at the northern boundary (located at 42°N) of the model domain. Comparison between CTRL and EXPT showed that, without extratropical forcing, there is weaker TSD activity in the June-to-August season, with reduced precipitation over the TSD pathway. Associated with suppressed TSD, southeastward-directed wave activity is also reduced, leading to less active mixed Rossby gravity (MRG) waves in the equatorial western Pacific area. Further analysis revealed that extratropical forcing and associated circulation changes can modulate the TSD wavetrain and its coherence structure, in relation to low-level vorticity in far western north Pacific. In CTRL, west of about 140°E, TSD-related circulation tends to be stronger; in EXPT, vorticity signals and vertical motions are found to be slightly more coherent in the more eastern portion of the TSD wavetrain. The latter enhanced coherency of TSD east of 140°E, from the EXPT simulations, might be due to changes in wave activity transport channelled by modulated upper-level mid-latitude westerlies in EXPT. Our results serve to quantify how extratropical forcing and related general circulation features influence western north Pacific summertime TSD activities. Implications on the understanding of initiation of TSD are discussed.

著者

Marín-Tello Carmen Zelada-Castillo Lorena Vásquez-Arqueros Alexander Vieira Amandio Siche Raúl

出版者

The United Graduate Schools of Agricultural Sciences, Japan

雑誌

Reviews in Agricultural Science (ISSN:2187090X)

巻号頁・発行日

vol.8, pp.323-342, 2020 (Released:2020-12-06)

参考文献数

143

被引用文献数

3 13

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The coffee shell or pulp is the first by-product obtained from the processing of coffee. It represents approximately 40 to 50% of the coffee berry’s weight. Currently, in much of the industry, it is a waste product with a major environmental impact on the water and soil, flora and fauna, and a problem to nearby populations in terms of odor and proliferation of insects and pathogenic microorganisms. This is a review that compiles alternative uses of coffee pulp in agriculture, food and nutrition, medicine and biotechnology. In food and agriculture, for example, the pulp can be used as organic fertilizer to improve degraded soils, in the biological control of plant pathogens, as food or substrate for microorganisms and worms, as feed for chickens, sheep, goats, fish and other animals, and in the productions of foods and beverages for human consumption. In biotechnology, coffee pulp can be used in the cultivation of edible fungi, production of enzymes, substrate for caffeine degrading microorganisms and for microorganisms that produce natural fungicides. Although many of these applications have been proposed and studied, there are also several novel uses that are in the early stages of development; for example, the use of pulp bioactive compounds to make food supplements, or to increase dietary fiber contents in foods and beverages, as well as for the production of biocontainers and biopackaging, alternatives to plastics and their serious environmental impact.

著者

Hiroyuki Matsuoka Gen-ichiro Sano Ryuta Hattori Hiroyuki Tomita Daisuke S. Yamamoto Makoto Hirai

出版者

Japanese Society of Tropical Medicine

雑誌

Tropical Medicine and Health (ISSN:13488945)

巻号頁・発行日

vol.40, no.2, pp.47-53, 2012 (Released:2012-10-05)

参考文献数

20

被引用文献数

1 4

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It has been proposed that transgenic mosquitoes can be used as a “flying syringe” for infectious disease control. We succeeded in generating a transgenic (TG) mosquito, Anopheles stephensi, excreting and discharging DsRed in saliva. DsRed was deposited on the membrane where the TG mosquito probed with its proboscis. Repeated feeding by the TG mosquitoes induced anti-DeRed as well as anti-SG antibodies in mice. This indicates that the TG mosquitoes can immunize the animal. Moreover, in this report, we employed a pre-immunization method before exposing mice to the TG mosquitoes. We injected DsRed to mice to prepare memory B cells and exposed the mice to bites by the TG mosquitoes excreting DsRed. The mice produced a higher titer of antibody to DsRed, suggesting that the bites from TG mosquitoes act as a booster and that primary immunization with a vaccine protein and exposure to TG mosquitoes excreting the vaccine protein in the saliva produces a synergistic effect.

著者

Rei Furukawa Nobuaki Kubo Ahmed El-Mowafy

出版者

The Institute of Electronics, Information and Communication Engineers

雑誌

IEICE Communications Express (ISSN:21870136)

巻号頁・発行日

vol.9, no.11, pp.529-534, 2020-11-01 (Released:2020-11-01)

参考文献数

4

被引用文献数

1 3

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The reflections and diffractions of global navigation satellite system (GNSS) signals from buildings may produce large measurement errors. Detecting non-line-of-sight signals using 3D maps is a means to detect and exclude satellites with large measurement errors. However, the true position is typically needed for using 3D maps. In this study, we verify the assumption that an approximate user position can be used when using 3D maps. We found that the correct fixed position of real-time kinematic GNSS (RTK-GNSS) could be achieved when approximate positions for RTK-GNSS assisted by 3D maps were within 5-15m from the true position.

著者

HIROSHI SUEMUNE TETSUJI HARABE ZHUO-FENG XIE KIYOSHI SAKAI

出版者

The Pharmaceutical Society of Japan

雑誌

Chemical and Pharmaceutical Bulletin (ISSN:00092363)

巻号頁・発行日

vol.36, no.11, pp.4337-4344, 1988-11-25 (Released:2011-02-08)

参考文献数

14

被引用文献数

20 33

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Asymmetric hydrolysis of 2, 2-bis (acetoxymethyl) cyclopentanone (5) using biocatalysts and its application to a formal synthesis of (-)-malyngolide are described.For the asymmetric induction at the quaternary carbon of 5, cholinesterase from electric eel was found to be effective to afford the (+)-monoacetate (6)(90%ee).Compound (+)-6 was easily converted to the synthetic intermediate (28) for (-)-malyngolide.

著者

GILLIS-FURUTAKA Amanda

出版者

京都産業大学

雑誌

京都産業大学論集. 人文科学系列 (ISSN:02879727)

巻号頁・発行日

no.47, pp.51-71, 2014-03

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YouTube was launched in 2005 as a site for people to share their home videos, but hasexpanded to become an unprecedented archive of freely available sound and visual aterial,as well as a platform for accessing the latest pop music releases. YouTube is also a major social networking site and is facilitating the exchange and appreciation of creative work both within and across national borders. These functions of YouTube will be discussed in relation to the findings of a two-stage research project with Japanese university undergraduates thatinvestigated how and why they use YouTube to access pop music. An initial survey of over2,000 first-year undergraduates was followed up by interviews with 51 students to find outthe ways in which they use YouTube in their daily lives.

著者

Shin-ichiro Agake Fernanda Plucani do Amaral Tetsuya Yamada Hitoshi Sekimoto Gary Stacey Tadashi Yokoyama Naoko Ohkama-Ohtsu

出版者

Japanese Society of Microbial Ecology / Japanese Society of Soil Microbiology / Taiwan Society of Microbial Ecology / Japanese Society of Plant Microbe Interactions / Japanese Society for Extremophiles

雑誌

Microbes and Environments (ISSN:13426311)

巻号頁・発行日

vol.37, no.1, pp.ME21060, 2022 (Released:2022-01-27)

参考文献数

61

被引用文献数

3

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Spores are a stress-resistant form of Bacillus spp., which include species that are plant growth-promoting rhizobacteria (PGPR). Previous studies showed that the inoculation of plants with vegetative cells or spores exerted different plant growth-promoting effects. To elucidate the spore-specific mechanism, we compared the effects of viable vegetative cells, autoclaved dead spores, and viable spores of Bacillus pumilus TUAT1 inoculated at 107 CFU plant–1 on the growth of the C4 model plant, Setaria viridis A10.1. B. pumilus TUAT1 spores exerted stronger growth-promoting effects on Setaria than on control plants 14 days after the inoculation. Viable spores increased shoot weight, root weight, shoot length, root length, and nitrogen uptake efficiency 21 days after the inoculation. These increases involved primary and crown root formation. Additionally, autoclaved dead spores inoculated at 108 or 109 CFU plant–1 had a positive impact on crown root differentiation, which increased total lateral root length, resulting in a greater biomass and more efficient nitrogen uptake. The present results indicate that an inoculation with viable spores of B. pumilus TUAT1 is more effective at enhancing the growth of Setaria than that with vegetative cells. The plant response to dead spores suggests that the spore-specific plant growth-promoting mechanism is at least partly independent of symbiotic colonization.

著者

金子 一郎 Marya S. Sabir Christopher M. Dussik G. Kerr Whitfield Amitis Karrys Jui-Cheng Hsieh Mark R. Haussler Mark B. Meyer J. Wesley Pike Peter W. Jurutka

出版者

公益社団法人 日本ビタミン学会

雑誌

ビタミン (ISSN:0006386X)

巻号頁・発行日

vol.91, no.2, pp.132-134, 2018 (Released:2018-04-12)

著者

猿渡 博輝 首藤-中野 友香 中野 兼宏 比良松 道一 尾崎 行生 大久保 敬

出版者

一般社団法人 園芸学会

雑誌

園芸学会雑誌 (ISSN:18823351)

巻号頁・発行日

vol.77, no.3, pp.312-317, 2008

被引用文献数

7

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タカサゴユリ(<i>Lilium formosanum</i> Wallace)は,種子発芽後 1 年以内に開花する早期開花性および複数花茎抽苔の形質を持つ.これらの形質の育種的利用価値を検討するために,花柱切断授粉法により種子親としてタカサゴユリ,花粉親としてヤマユリ(<i>L. auratum</i>),カノコユリ(<i>L.</i> <i>speciosum</i>),リーガルユリ(<i>L. regale</i>),'ロリポップ','ピンクタイガー','ザザ','ル・レーヴ','マルコ・ポーロ'および'アフリカンクィーン'を用いた 9 組み合わせの種間交雑を行い,その後,子房切片培養を行った.すべての交雑組み合わせで発芽が観察され,雑種を 53 個体得ることができた.そのうち 30 個体(56.6%)および同様の手法を用いて作出したタカサゴユリ自家交配実生は発芽後 24 か月以内に開花した.開花雑種個体のうち 11 個体(36.7%)では 2~4 本の花茎が抽台した.早期開花性,複数花茎抽苔および有色花を同時に合わせ持つ雑種は,タカサゴユリと有色花アジアティックハイブリッドユリとの交配から 4 個体得られた.これらの結果は,タカサゴユリと有色花のアジアティックハイブリッドユリと交配すれば,3 つの有用形質,すなわち,早期開花性,複数花茎抽苔および有色花を同時に合わせ持つユリを育種できる可能性を示唆している.<br>

著者

Shin-ichi Momomura Yoshihiko Saito Yoshio Yasumura Kazuhiro Yamamoto Yasushi Sakata Masao Daimon Koichiro Kinugawa Hiroshi Okamoto Naoki Dohi Issei Komuro

出版者

The Japanese Circulation Society

雑誌

Circulation Journal (ISSN:13469843)

巻号頁・発行日

pp.CJ-17-0532, (Released:2017-08-02)

参考文献数

10

被引用文献数

5 8

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Background:TY-0201 (TY) is a transdermal formulation of bisoprolol that is the free base of bisoprolol fumarate (BO), a drug widely used to treat chronic heart failure (CHF). The objectives of this phase II study were to evaluate the efficacy and safety of TY when switching from oral BO to TY in patients with CHF whose drug therapy was optimized, and to determine the dose conversion rate of BO to TY.Methods and Results:The efficacy and safety of once daily TY patch use for 16 weeks was investigated in 40 patients with CHF who were stabilized with an optimized drug treatment, including BO, after switching from BO to TY at the dose conversion rate of 5:8. The pre-switch left ventricular ejection fraction was 50.13±11.09% (mean±SD). The post-switch value was 50.87±10.79% after 16 weeks, which was not significantly different, with similar results for other efficacy and safety parameters. The 16-week study was continued for all patients without changing doses after switching to TY. No cardiovascular deaths, hospitalizations for worsening HF, or significant safety concerns were observed.Conclusions:Efficacy was maintained without significant safety concerns in patients with CHF who were stabilized with BO treatment after switching to TY, suggesting the appropriateness of the dose conversion rate.

著者

Matsuda Yoichi Nishida-Umehara Chizuko Tarui Hiroshi Kuroiwa Asato Yamada Kazuhiko Isobe Taku Ando Junko Fujiwara Atushi Hirao Yukako Nishimura Osamu Ishijima Junko Hayashi Akiko Saito Toshiyuki Murakami Takahiro Murakami Yasunori Kuratani Shigeru Agata Kiyokazu

出版者

Springer Netherlands

雑誌

Chromosome Research (ISSN:09673849)

巻号頁・発行日

vol.13, no.6, pp.601-615, 2005-08

被引用文献数

97

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The karyotypes of birds, turtles and snakes are characterized by two distinct chromosomal components, macrochromosomes and microchromosomes. This close karyological relationship between birds and reptiles has long been a topic of speculation among cytogeneticists and evolutionary biologists; however, there is scarcely any evidence for orthology at the molecular level. To define the conserved chromosome synteny among humans, chickens and reptiles and the process of genome evolution in the amniotes, we constructed comparative cytogenetic maps of the Chinese soft-shelled turtle (Pelodiscus sinensis) and the Japanese four-striped rat snake (Elaphe quadrivirgata) using cDNA clones of reptile functional genes. Homology between the turtle and chicken chromosomes is highly conserved, with the six largest chromosomes being almost equivalent to each other. On the other hand, homology to chicken chromosomes is lower in the snake than in the turtle. Turtle chromosome 6q and snake chromosome 2p represent conserved synteny with the chicken Z chromosome. These results suggest that the avian and turtle genomes have been well conserved during the evolution of the Arcosauria. The avian and snake sex Z chromosomes were derived from different autosomes in a common ancestor, indicating that the causative genes of sex determination may be different between birds and snakes.

著者

Junya Hirai Syun-ichi Urayama Yoshiro Takaki Miho Hirai Keizo Nagasaki Takuro Nunoura

出版者

Japanese Society of Microbial Ecology / Japanese Society of Soil Microbiology / Taiwan Society of Microbial Ecology / Japanese Society of Plant Microbe Interactions / Japanese Society for Extremophiles

雑誌

Microbes and Environments (ISSN:13426311)

巻号頁・発行日

vol.37, no.5, pp.ME21066, 2022 (Released:2022-01-01)

参考文献数

61

被引用文献数

2

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Zooplankton and viruses play a key role in marine ecosystems; however, their interactions have not been examined in detail. In the present study, the diversity of viruses associated with zooplankton collected using a plankton net (mesh size: 100‍ ‍μm) in the subtropical western North Pacific was investigated by fragmented and primer ligated dsRNA sequencing. We obtained 21 and 168 operational taxonomic units (OTUs) of ssRNA and dsRNA viruses, respectively, containing RNA-dependent RNA polymerase (RdRp). These OTUs presented average amino acid similarities of 43.5 and 44.0% to the RdRp genes of known viruses in ssRNA viruses and dsRNA viruses, respectively. Dominant OTUs mainly belonged to narna-like and picorna-like ssRNA viruses and chryso-like, partiti-like, picobirna-like, reo-like, and toti-like dsRNA viruses. Phylogenetic ana­lyses of the RdRp gene revealed that OTUs were phylogenetically diverse and clustered into distinct clades from known viral groups. The community structure of the same zooplankton sample was investigated using small subunit (SSU) rRNA sequences assembled from the metatranscriptome of single-stranded RNA. More than 90% of the sequence reads were derived from metazoan zooplankton; copepods comprised approximately 70% of the sequence reads. Although this ana­lysis provided no direct evidence of the host species of RNA viruses, these dominant zooplankton are expected to be associated with the RNA viruses detected in the present study. The present results indicate that zooplankton function as a reservoir of diverse RNA viruses and suggest that investigations of zooplankton viruses will provide a more detailed understanding of the role of viruses in marine ecosystems.

著者

Yoshinori TAKAMI Kyung-Ok NAM Youki TAKAKI Sho KADEKARU Chizuka HEMMI Tsuyoshi HOSOYA Yumi UNE

出版者

JAPANESE SOCIETY OF VETERINARY SCIENCE

雑誌

Journal of Veterinary Medical Science (ISSN:09167250)

巻号頁・発行日

pp.21-0177, (Released:2021-06-25)

被引用文献数

8

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Ophidiomycosis is an emerging infectious disease caused by the fungus Ophidiomyces ophiodiicola, which has been affecting wild and captive snakes in North America, Europe, and Australia. We report 12 cases of suspected ophidiomycosis in captive colubrid snakes in Japan. Pathological and microbiological examinations were performed, and the results confirmed the diagnosis of ophidiomycosis in two snakes, which indicated that the remaining sympatrically raised snakes also had ophidiomycosis since they exhibited similar lesions. This is the first report of ophidiomycosis in Asia caused by O. ophiodiicola. To prevent the expansion of ophidiomycosis in the natural environment in Japan, there is a need to evaluate the ophidiomycosis carrier status of imported snakes, the pathogenicity of the infection in native snakes, and the prevalence and distribution of O. ophiodiicola in wild and captive snakes. Measures also must be taken to prevent endemicity globally.

著者

黄 國賓 杉浦 康平 Kuo-pin HUANG Kohei SUGIURA

出版者

神戸芸術工科大学

雑誌

芸術工学2021

巻号頁・発行日

2021-11-24

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チベット・ブータン・ネパール・ラダックなどのチベット仏教文化圏の数多いチャム(chams) のなかに、僧侶たちが真黒に近い絢爛たる緞子の衣装をまとい、黒色を主役とした重厚で威厳のある独特な大きな黒い帽子をかぶった、「シャナの舞」と呼ばれる踊りがある。 チャムに関する研究はこれまで、音楽、舞踊、宗教的儀式などの視点で多大な研究成果が見られる。しかしいずれもが個別的な研究であり、チベット仏教におけるシャナ冠の造形とそれに関わる聖山信仰、シャナ冠を構成する各モチーフの象徴的意味の解読からシャナ冠の特異な造形原理を統合的な研究への探求は未だ見られない。 本研究では、デザイン学の視点から地域差によって生み出されたチベット仏教文化圏に共通するシャナ冠と須弥山、曼荼羅との関連、およびその影響を受けたとされる日本の仏教文化との関連する造形、図像の象徴性、意味性を比較しながら、これまでに明らかにされなかったシャナ冠の造形原理の象徴性を明らかにする。