著者

井原 廣一

雑誌

情報処理

巻号頁・発行日

vol.23, no.4, 1982-04-15

著者

岩佐 貫三

出版者

Japanese Association of Indian and Buddhist Studies

雑誌

印度學佛教學研究 (ISSN:00194344)

巻号頁・発行日

vol.25, no.1, pp.387-390, 1976-12-25 (Released:2010-03-09)

著者

片山 静治

出版者

The Textile Machinery Society of Japan

雑誌

繊維機械学会誌 (ISSN:03710580)

巻号頁・発行日

vol.25, no.10, pp.P653-P664, 1972-10-20 (Released:2009-10-27)

参考文献数

19

著者

草薙 忠明

出版者

The Society of Resource Geology

雑誌

鉱山地質 (ISSN:00265209)

巻号頁・発行日

vol.5, no.16, pp.77-88, 1955-07-05 (Released:2009-06-12)

参考文献数

14

被引用文献数

1

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The funnel or basin shaped rhyolitic complex occupies almost the whole area of the Ashio mining district, and its surface distribution makes an imperfect ellipse-like outline, reaching about 3.3km in its minor axis and about 4.4 km in major axis, and the volcanic activities of these volcanic complex are supposed to have taken place in the late Tertiary period.The rhyolitic complex is composed of rhyolite massive flow and rhyolitic pyroclastics, such as volcanic breccia, tuff, tuff breccia, lapilli tuff and also welded tuff. They are accumulated alternately, forming nearly horizontal beds. The lower part of the complex consists mainly of rhyolitic lava, intercalating some rhyolitic volcanic breccia and tuff. In the upeer parts are found alternations of tuff breccia, lappili tuff and welded tuff, the last one being most conspicuous. Thus, the volcanic complex of the Ashio mining district seems to form a stratovolcano.The basal breccia, named by the writer, occurs along the contact surface between the rhyolitic complex and the Palaeozoic sediments or sometimes the late-Mesozoic granodiorite of basement complex, and is composed mainly of angular or subangular fragments of basal rocks, such as chert, clay slate, sandstone, siliceous slate, schalstein and granodiorite. Judging from the mode of occurence, it may be concluded that the basal breccia is not of explosion, but of talus origin, formed on the steep slope of the wall of the basin.The funnel or basin shaped hollow, filled up with rhyolitic rocks, may represent a caldera, formed by the depression preceding the volcanic explosion. The central vents of this rhyolitic volcano are supposed to be situated near the pyrophyllitized and brecciated zone of Tenguzawa, and the original crater, now indistinct by erosion, might be located also at the same place.Fissure veins are formed abundantly in rhyolite flow and welded tuff, but scantly in tuff and tuff breccia. Ore shoots of veins are mostly localized in favorable beds such as rhyolite or rhyolitic welded tuff, which lies nearly horizontally, and then the shoots may have a flat elongation. The localization of ore shoots may be attributed mainly to the deflection of each vein according to the different physical characters of each bed. Bonanzas of so-called "Kajika type" are formed sometimes in tuff and tuff breccia, only when the fissure veins swarm closely, though it is not the case where an isolated vein is present.

著者

Satoshi WATANABE Naofumi YOSHIDA Kairi BABA Hiroyuki YAMASAKI Natsuko O. SHINOZAKI Masato OGAWA Tomoya YAMASHITA Aya K. TAKEDA

出版者

BMFH Press

雑誌

Bioscience of Microbiota, Food and Health (ISSN:21863342)

巻号頁・発行日

pp.2022-047, (Released:2023-10-18)

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Gut microbiota imbalance plays an important role in the pathogenesis of various diseases. Here, we determined microbe–microbe interactions and gut microbiome stability in a Japanese population with varying body mass indices (BMIs) and enterotypes. Using 16S ribosomal RNA gene sequencing, we analyzed gut microbial data from fecal samples obtained from 3,365 older Japanese individuals. The individuals were divided into lean, normal, and obese groups based on their BMIs. They were further categorized according to their gut microbiota enterotypes: Bacteroides (enterotype B), Prevotella (enterotype P), and Ruminococcus (enterotype R). We obtained data on different host factors, such as age, BMI, and disease status, using a survey questionnaire evaluated by the Mykinso gut microbiome testing service. Subsequently, we evaluated the co-occurrence network. Individual differences in BMI were associated with differences in co-occurrence networks. By exploring the network topology based on BMI status , we observed that the network density was lower in the lean group than that in the normal group. Furthermore, a simulation-based stability analysis revealed a lower resistance index in the lean group than those in the other two groups. Our results provide insights into various microbe–microbe interactions and gut microbial stability and could aid in developing appropriate therapeutic strategies targeting gut microbiota modulation to manage frailty.

著者

渡邉 ゆきこ

出版者

情報処理学会

雑誌

情報処理

巻号頁・発行日

vol.64, no.11, pp.604-607, 2023-10-15

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筆者が2021年から行っている「Mozilla Hubs」(モジラ・ハブス)というソーシャルVRプラットフォームを活用した初級中国語の授業の実践報告.モジラ・ハブスは,デバイスに依存しないブラウザベースのメタバースであり,多様なモデルシーンを持つ上,直感的に操作可能な編集機能を備えていることがその特徴である.利用している無料プランでは仮想空間の定員が10人と少ないが,同じ空間を複製する機能を活かして活用の幅を広げた.活用例として,海外の大学との交流授業,学生が制作した動画をVR空間に展示するVRポートフォリオ,さらに4つのカテゴリーに分けられる教材としての利用などを報告している.

著者

Atsushi Nakamoto Hiromitsu Onishi Takahiro Tsuboyama Hideyuki Fukui Takashi Ota Keigo Yano Kengo Kiso Toru Honda Hiroyuki Tarewaki Yoshihiro Koyama Mitsuaki Tatsumi Noriyuki Tomiyama

出版者

Japanese Society for Magnetic Resonance in Medicine

雑誌

Magnetic Resonance in Medical Sciences (ISSN:13473182)

巻号頁・発行日

pp.mp.2023-0039, (Released:2023-10-28)

参考文献数

25

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Purpose: To compare objective and subjective image quality, lesion conspicuity, and apparent diffusion coefficient (ADC) of high-resolution multiplexed sensitivity-encoding diffusion-weighted imaging (MUSE-DWI) with conventional DWI (c-DWI) and reduced FOV DWI (rFOV-DWI) in prostate MRI.Methods: Forty-seven patients who underwent prostate MRI, including c-DWI, rFOV-DWI, and MUSE-DWI, were retrospectively evaluated. SNR and ADC of normal prostate tissue and contrast-to-noise ratio (CNR) and ADC of prostate cancer (PCa) were measured and compared between the three sequences. Image quality and lesion conspicuity were independently graded by two radiologists using a 5-point scale and compared between the three sequences.Results: The SNR of normal prostate tissue was significantly higher with rFOV-DWI than with the other two DWI techniques (P ≤ 0.01). The CNR of the PCa was significantly higher with rFOV-DWI than with MUSE-DWI (P < 0.05). The ADC of normal prostate tissue measured by rFOV-DWI was lower than that measured by MUSE-DWI and c-DWI (P < 0.01), while there was no difference in the ADC of cancers. In the qualitative analysis, MUSE-DWI showed significantly higher scores than rFOV-DWI and c-DWI for visibility of anatomy and overall image quality in both readers, and significantly higher scores for distortion in one of the two readers (P < 0.001). There was no difference in lesion conspicuity between the three sequences.Conclusion: High-resolution MUSE-DWI showed higher image quality and reduced distortion compared to c-DWI, while maintaining a wide FOV and similar ADC quantification, although no difference in lesion conspicuity was observed.

著者

Yoshitaka Bito Hisaaki Ochi Ryuji Shirase Wataru Yokohama Kuniaki Harada Kohsuke Kudo

出版者

Japanese Society for Magnetic Resonance in Medicine

雑誌

Magnetic Resonance in Medical Sciences (ISSN:13473182)

巻号頁・発行日

pp.mp.2023-0081, (Released:2023-10-27)

参考文献数

33

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Purpose: Analysis of cerebrospinal fluid (CSF) dynamics may be beneficial for understanding the mechanisms and diagnosis of several neurological diseases. Low b-value diffusion tensor imaging (low-b DTI) is useful for observing the slow and complex motion of the CSF. Theoretically, a mathematical framework suggests that low-b DTI provides the variance of the pseudorandom motion of the CSF. Furthermore, low-b DTI could provide comprehensive information on fluid dynamics. Accordingly, we proposed an analysis technique that resolves intravoxel pseudorandom motion into ordered (linear) and disordered (random) motions based on the mathematical framework.Methods: The proposed analysis technique helps measure low-b DTI with multiple diffusion times and linearly fits its mean diffusivity (MD) with the diffusion time to obtain two parameters, double-slope Vv and y-intersect Dr, which represent the variance of the velocity distribution of linear motion and the diffusion coefficient of random motion, respectively. Seven healthy subjects were scanned to evaluate the proposed technique and investigate fluid dynamics in several representative ROIs.Results: The obtained data showed the validity of the technique, repeatability, and consistency across the subjects in ROIs, such as the lateral ventricle (LV), third ventricle (3V), fourth ventricle (4V), and Sylvian fissure (SF). The obtained parameters Vv and Dr highlighted different characteristics of fluid dynamics in the representative ROIs: low Vv and low Dr in the LV, high Vv and moderate Dr in the 3V, and moderate Vv and moderate Dr in the 4V and SF.Conclusion: The proposed analysis technique will facilitate a comprehensive investigation of the complex dynamics of the CSF using resolved parameters representing ordered and disordered motions.

著者

Yasuhiro Yamamoto Hiromi Koma Sayaka Nishii Tatsurou Yagami

出版者

The Pharmaceutical Society of Japan

雑誌

Biological and Pharmaceutical Bulletin (ISSN:09186158)

巻号頁・発行日

vol.40, no.4, pp.402-412, 2017-04-01 (Released:2017-04-01)

参考文献数

46

被引用文献数

5 5

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Heat shock protein 70 (Hsp70) is not only a molecular chaperone in cytosol, but also presents in synaptic plasma membranes. To detect plasmalemmal Hsp70 (pl-Hsp70), neurons were immunostained with anti-Hsp70 antibody without permeabilization and fixation. Dotted immunofluorescent signals at neuronal cell bodies and neurites indicated the localization of Hsp70 on the neuronal cell surface. To target only pl-Hsp70, but not cytosolic Hsp70, the anti-Hsp70 antibody was applied without permeabilization in the primary culture of rat cortical neurons. The antibody induced neuronal cell death in a concentration-dependent manner. The anti-Hsp70 antibody activated ubiquitin-proteasome pathway, but inactivated caspase-3. A lag time was required for the neurotoxicity of anti-Hsp70 antibody. Hydrogen peroxide was increased in the anti-Hsp70 antibody-treated neurons during the lag time. Catalase suppressed the anti-Hsp70 antibody-reduced cell viability via the plausible inhibition of hydrogen peroxide generation. One of down-streams of hydrogen peroxide exposure is activation of the mitogen-activated protein kinase (MAPK) signaling cascade. The neurotoxicity of anti-Hsp70 antibody was partially ascribed to c-Jun N-terminal kinase among MAPKs. In conclusion, the anti-Hsp70 antibody targeted pl-Hsp70 on the neuronal cell surface and induced neuronal cell death without complement. Furthermore, hydrogen peroxide appeared to mediate the neuronal cell death, which was accompanied with the enhancement of the ubiquitin–proteasome pathway and the suppression of caspase in a different fashion from the known cell death.

著者

田村 浩二 長谷川 典巳

出版者

生命の起原および進化学会

雑誌

Viva Origino (ISSN:09104003)

巻号頁・発行日

vol.41, no.4, pp.29-33, 2013 (Released:2021-12-29)

参考文献数

29

著者

西山 豊

出版者

日本科学者会議

雑誌

日本の科学者 (ISSN:00290335)

巻号頁・発行日

vol.56, no.8, pp.37-40, 2021 (Released:2023-10-26)

著者

正田 悦朗 石川 斉 広畑 和志 渡辺 信

出版者

日本炎症・再生医学会

雑誌

炎症 (ISSN:03894290)

巻号頁・発行日

vol.4, no.4, pp.535-538, 1984-11-01 (Released:2010-04-12)

参考文献数

7

著者

石黒 正揮 山崎 重一郎 佐々木 貴之

出版者

情報処理学会

雑誌

情報処理

巻号頁・発行日

vol.64, no.10, pp.520-523, 2023-09-15

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暗号資産,デジタル所有権NFT,分散型自立組織DAOなどブロックチェーン技術をベースとした応用・サービスはWeb3.0と呼ばれ,従来のインターネット経済に大きなパラダイム転換をもたらすものとして注目されている.政府においても,内閣府,経産省,総務省などによりWeb3.0経済の推進に向けて検討が進められている.一方で,国内外においてWeb3.0に対する大規模なハッキングや事件が繰り返し発生し,Web3.0経済の発展の障害となっている.本特集では,Web3.0の普及に向けて,Web3.0のリスクや課題を明らかにするとともに,それらに対する解決の方向性,将来展望を示す.

著者

Yuhei ITO Takao KOJIMA Takuya MAEDA Masazumi FUJII

出版者

The Japan Neurosurgical Society

雑誌

NMC Case Report Journal (ISSN:21884226)

巻号頁・発行日

vol.10, pp.299-302, 2023-12-31 (Released:2023-10-14)

参考文献数

13

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Le Fort I osteotomy is a common surgical technique for correcting jaw deformities. Although it is generally a safe procedure, there have been cases of postoperative vascular complications, which include arteriovenous fistulas. Published reports describe the development of arteriovenous fistulas that originate from the maxillary artery after this procedure; nevertheless, no cases of arteriovenous fistulas arising from the middle meningeal artery (MMA) have been reported. We present the case of a 19-year-old woman who developed pulsatile tinnitus immediately following a Le Fort I osteotomy. Angiography with proximal flow control of the external carotid artery showed an arteriovenous fistula between the extracranial portion of the MMA and the pterygoid venous plexus. The fistula was successfully treated using coil embolization, preserving the maxillary artery, which results in tinnitus resolution. In this report, the effectiveness of endovascular treatment for arteriovenous fistulas of the MMA that occur following a Le Fort I osteotomy was demonstrated. Angiography with proximal flow interruption was effective in shunt location detection.

著者

Kohei Ikeda Hiroshi Tanimoto Yugo Kanaya Fumikazu Taketani Atsushi Matsuki

出版者

公益社団法人 日本気象学会

雑誌

SOLA (ISSN:13496476)

巻号頁・発行日

vol.19, pp.239-245, 2023 (Released:2023-10-11)

参考文献数

23

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We evaluated the mass concentration levels and long-term trends of black carbon (BC) in the historical and future scenario simulations using 12 climate models from the Coupled Model Intercomparison Project Phase 6 (CMIP6) for East Asia, the region with the largest anthropogenic emissions. By comparing them with surface observations at two regionally representative sites, Fukue and Noto, for the period of 2009-2020, we found that the CMIP6 multi-model mean was approximately two times higher than the observed BC concentrations and did not reproduce the observed decreasing trend before 2014. Sensitivity simulations of emission inventories using a chemical transport model, GEOS-Chem, suggested that the overestimation and increasing trend of Chinese BC emissions in the CMIP6 historical inventory (CEDSv2017-05-18) were responsible for the higher concentrations and opposite trends in the CMIP6 BC simulations. The direct radiative effect of BC for CEDS was estimated to be 72% larger in East Asia than that for the ECLIPSEv6b inventory, which reproduced the observed BC concentrations reasonably well.

著者

草薙 忠明

出版者

The Society of Resource Geology

雑誌

鉱山地質 (ISSN:00265209)

巻号頁・発行日

vol.13, no.58-59, pp.95-100, 1963-04-30 (Released:2009-06-12)

参考文献数

9

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The Ashio Mine is composed mainly of the rhyolitic comlex and the Palaeozoic formation. The ore deposits occur both in them as vein and "Kajika" deposits.Four hypogene mineral zones, a central Sn-W-Bi-Cu zone, an intermediate Cu-As-Zn zone, a marginal Zn-Pb-Cu-As zone and a barren zone are quite distinguished in the rhyolitic complex as Takeshi NAKAMURA (1961) clarified them.Hypogene mineralization in the Palaeozoic formation and in the southern part of the rhyolitic complex adjacent to the Palaeozoic formation is very similar to that in the rhyolitic complex, but large amounts of ealier pyrrhotite and marmatite occur in the Palaeozoic formation. In general, three mineral zones, a Fe-Zn-As zone, a Cu zone and a silicified and barren zone are distinguished remarkably from the foot-wall side to the hanging-wall side of the "Kajika" deposits in the Palaeozoics.The mineralizations both in the rhyolitic complex and the Palaeozoics are considered to be taken place at the same time after the rhyolitic complex extruded.The features of the high-temperature tin and tungsten minerals are associated with the low-temperature copper, lead, zinc and other minerals show the telescoped character of the Ashio deposits. The ore deposits at the Ashio Mine classified as the epithermal deposit are considered to be formed under the subvolcanic environment caused by the vocanism of the Ashio rhyolitic complex.

著者

森本 淳子 柴田 昌三 長谷川 秀三

出版者

日本緑化工学会

雑誌

日本緑化工学会誌 (ISSN:09167439)

巻号頁・発行日

vol.29, no.2, pp.360-366, 2003 (Released:2005-10-25)

参考文献数

17

被引用文献数

2 2

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京都市近郊林産のコバノミツバツツジとモチツツジの地域性種苗の生産に必要な技術,すなわち種子の貯蔵,播種,苗の育成に関して,適切な方法を明らかにすることを目的に実験を行った。その結果,1)当年結実した果実を採取後,乾燥させ取り出した種子を殺菌処理し冷蔵乾燥貯蔵すると,種子の発芽力は低下しにくい,2)この条件で貯蔵すると,コバノミツバツツジは少なくとも2 年8 カ月間,モチツツジは1 年8 カ月間,高い発芽力が維持される,3)結実の翌年,気象をコントロールしないガラス室で5 月頃に播種すると発芽率は最も高くなる,4)施肥を行わない場合,コバノミツバツツジは水苔に播種し翌年早春に6 cmポットに床替え,モチツツジは水苔に播種し翌年早春に9 cmポットに床替えすると,もっとも生存率が高く,成長量の大きい2年生苗になることが明らかになった。

著者

稲葉 幸雄 吉田 智彦 杉山 信男

出版者

一般社団法人 園芸学会

雑誌

園芸学研究 (ISSN:13472658)

巻号頁・発行日

vol.6, no.3, pp.431-434, 2007 (Released:2007-07-24)

参考文献数

16

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代表的な促成栽培用品種である‘とちおとめ’,‘女峰’および‘とよのか’を用いて,主茎腋芽の発達に及ぼす定植後の温度と施肥量の影響を検討した.植物体は温度条件と施肥量を各2段階に変え,これらを組み合わせた4条件下で栽培した.頂花房直下の腋芽を第1節腋芽とし,第4節までの腋芽のタイプを定植後52日目に調べた.腋芽は休眠芽,一次側枝,ランナーに分類した.3品種とも第1節腋芽はすべて一次側枝に発達した.いずれの品種でも第3,4節の腋芽は低温下では休眠芽となるものが多かったが,高温下ではランナーとなるものが増加した.‘とちおとめ’,‘女峰’では施肥量が増えると休眠芽の割合が減少したが,‘とよのか’では施肥量の影響は小さかった.第2節では,休眠芽の割合は低く,高温下でランナーの割合が増加した.施肥量が増えると,‘とちおとめ’では一次側枝の割合が増加したが,他の2品種では一次側枝の割合はほとんど変化しなかった.以上の結果は,第2節の腋芽の発達を調節するため,品種によって温度や施肥条件を変える必要があることを示唆している.