著者

村田 武士

出版者

一般社団法人 日本生物物理学会

雑誌

生物物理 (ISSN:05824052)

巻号頁・発行日

vol.54, no.2, pp.079-084, 2014 (Released:2014-03-28)

参考文献数

28

被引用文献数

1 1

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F- and V-ATPases are unique bio- and nano-molecular rotary motors among many types of bioenergy-transducing machineries. The rotational catalysis of F1-ATPase has been investigated in detail, and the molecular mechanisms have been proposed on the basis of crystal structures of the complex and extensive single-molecule observation of the rotation. Recently, we have obtained crystal structures of bacterial V1-ATPase (A3B3 and A3B3DF complexes) with and without nucleotide. On the basis of these new structures, we present a novel model of the rotational catalytic mechanism for V1-ATPase, which is apparently different from those of F1-ATPases.

著者

速川 和男

出版者

日本英語教育史学会

雑誌

日本英語教育史研究 (ISSN:0916006X)

巻号頁・発行日

vol.1, pp.57-81, 1986-05-15 (Released:2012-10-29)

著者

Kotaro Ozasa Eric J Grant Kazunori Kodama

出版者

Japan Epidemiological Association

雑誌

Journal of Epidemiology (ISSN:09175040)

巻号頁・発行日

vol.28, no.4, pp.162-169, 2018-04-05 (Released:2018-04-05)

参考文献数

66

被引用文献数

1 69

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Cohorts of atomic bomb survivors—including those exposed in utero—and children conceived after parental exposure were established to investigate late health effects of atomic bomb radiation and its transgenerational effects by the Atomic Bomb Casualty Commission (ABCC) in the 1950s. ABCC was reorganized to the Radiation Effects Research Foundation (RERF) in 1975, and all work has been continued at RERF. The Life Span Study, the cohort of survivors, consists of about 120,000 subjects and has been followed since 1950. Cohorts of in utero survivors and the survivors’ children include about 3,600 and 77,000 subjects, respectively, and have been followed since 1945. Atomic bomb radiation dose was estimated for each subject based on location at the time of the bombing and shielding conditions from exposure, which were obtained through enormous efforts of investigators and cooperation of subjects. Outcomes include vital status, cause of death, and cancer incidence. In addition, sub-cohorts of these three cohorts were constructed to examine clinical features of late health effects, and the subjects have been invited to periodic health examinations at clinics of ABCC and RERF. They were also asked to donate biosamples for biomedical investigations. Epidemiological studies have observed increased radiation risks for malignant diseases among survivors, including those exposed in utero, and possible risks for some non-cancer diseases. In children of survivors, no increased risks due to parental exposure to radiation have been observed for malignancies or other diseases, but investigations are continuing, as these cohorts are still relatively young.

著者

大橋 容一郎

出版者

岩波書店

雑誌

思想 (ISSN:03862755)

巻号頁・発行日

no.1118, pp.130-147, 2017-06

著者

楊枝 嗣朗 ヨウジ シロウ Yoji shiro

出版者

佐賀大学経済学会

雑誌

佐賀大学経済論集 / 佐賀大学経済学会 (ISSN:02867230)

巻号頁・発行日

vol.51, no.1, pp.43-66, 2018-05

著者

佐々木 良造 薄井 良子 Ryozo Sasaki Yoshiko Usui

雑誌

関西学院大学日本語教育センター紀要

巻号頁・発行日

no.2, pp.5-19, 2013-03-05

出版者

ベテランママの会

巻号頁・発行日

2014

著者

国立国会図書館総務部

出版者

国立国会図書館

巻号頁・発行日

vol.平成28年度, 2017-12-15

著者

吉原 重美

出版者

一般社団法人 日本アレルギー学会

雑誌

アレルギー (ISSN:00214884)

巻号頁・発行日

vol.64, no.6, pp.826-828, 2015 (Released:2015-10-31)

参考文献数

15

著者

山中 亮一 上月 康則 野上 文子 魚谷 昂一郎 三好 真千 五島 幸太郎

出版者

公益社団法人 土木学会

雑誌

土木学会論文集B2(海岸工学) (ISSN:18842399)

巻号頁・発行日

vol.68, no.2, pp.I_1206-I_1210, 2012 (Released:2012-11-15)

参考文献数

12

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Mytilus galloprovincialis (mussel) is a dominant species that attach to seawalls in eutrophied enclosed ports in Japan. Mussel drop-off occurrs every summertime causing sediment contamination at the sea bottom. To avoid the occurrence of mussel drop-off, we suggest to harvest an attached mussel just before the drop-off and composting it. To predict the occurrence of the mussel drop-off, we have to investigate it's biological reaction to influential factors, especially water quality variation. Therefore, we conduct the field observation and reaction experiment of mussels. As a result, we clarified that adhesion characteristics of mussels are affected by the pattern of water quality variation and caused by internal seiche which improves the number of byssus of the mussels.

著者

阿南 大

出版者

東洋学園大学

雑誌

東洋学園大学紀要 (ISSN:09196110)

巻号頁・発行日

no.18, pp.75-88, 2010-03

著者

高野 裕佑 半谷 眞七子 立松 三千子 中村 千賀子 阿部 恵子 藤崎 和彦 亀井 浩行

出版者

公益社団法人 日本薬学会

雑誌

YAKUGAKU ZASSHI (ISSN:00316903)

巻号頁・発行日

vol.135, no.12, pp.1387-1395, 2015 (Released:2015-12-01)

参考文献数

32

被引用文献数

4

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We performed a survey of cancer patients' needs for drug treatment and support from pharmacists during treatment and evaluated the support that cancer patients can expect from community pharmacists in the future. The patients consisted of 16 members of the Cancer Patient Association in Aichi prefecture who underwent chemotherapy. The results of a semistructured group interview were qualitatively analyzed using the grounded theory method. Patients undergoing chemotherapy had high hopes for its effectiveness but were worried about side effects and medical costs. To overcome these problems, they hoped for a decrease in the economic burden, compassionate-use system, and development of novel drugs. The patients had anxiety because the side effects of chemotherapy often caused physical and psychological damage. Despite patients' confusion, pharmacists sometimes did not give adequate explanations to them. The patients expected more from pharmacists regarding medication support and hoped for a system allowing continuous side effect monitoring and consultation without hesitation. For patients undergoing cancer chemotherapy who are confused regarding side effects, pharmacists should understand the patient explanatory model and become more involved with patients as partners in treatment.

著者

栗原 由紀子 Yukiko Kuribara

出版者

尚絅学院大学

雑誌

尚絅学院大学紀要 (ISSN:13496883)

巻号頁・発行日

vol.57, pp.33-45, 2009-04

著者

溝辺 泰雄

出版者

明治大学人文科学研究所

雑誌

明治大学人文科学研究所紀要 (ISSN:05433894)

巻号頁・発行日

vol.80, pp.2-34, 2017-03

著者

津田房之助 著

出版者

矢島誠進堂

巻号頁・発行日

vol.地, 1895

著者

松井 広志 井口 貴紀 大石 真澄 李 天能

出版者

[愛知淑徳大学] 創造表現学部論集編集委員会

雑誌

愛知淑徳大学論集. 創造表現学部篇 = Bulletin of Aichi Shukutoku University. [愛知淑徳大学] 創造表現学部論集編集委員会 編

巻号頁・発行日

no.7, pp.23-38, 2017

著者

森 良和

出版者

玉川大学教育学部

雑誌

論叢 : 玉川大学教育学部紀要 (ISSN:13483331)

巻号頁・発行日

pp.117-134, 2016

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ウィリアム・アダムズ(三浦按針)の日本人妻の人物像については従来ほとんど踏み込んだ研究はなされていない。史料がごく限られるからである。しかし,これまでは特に吟味されることなく,夫人の出自と名前が「馬込勘解由の娘おゆき」とされることが多かった。本稿では主に当時来日していた西洋人の記録を検証しながら,これらについて改めて考察し,自身の見解を示していく。

著者

本岡 拓哉

出版者

The Association of Japanese Geographers

雑誌

日本地理学会発表要旨集

巻号頁・発行日

pp.100305, 2014 (Released:2014-03-31)

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第二次世界大戦の終戦直後からおよそ1970年代終わりまでの間、都市部の河川敷の中には居住の場として存在していたところも多かった。すなわち、戦災都市の河川敷にはセルフビルドのバラックが建ち並び、「不法占用/不法占拠」「スラム」というレッテルを受けながらも、河川敷は居住の場としての機能を有していたのである。とりわけ住宅差別を受けた在日コリアンなどの社会的周縁層、経済的社会的弱者たちもそうした河川敷に留まることとなったが、その一方で、都市部の河川敷は養豚業や廃品回収業などにも適した環境であったため、かれらはこうしたインフォーマルな労働によって賃金を獲得することも可能であった。しかし、戦災復興による都市化、さらには1964年の「新河川法」制定を契機に、河川敷の整備は進み、その景観は大きく変容し、河川敷居住は消滅していくことになった。本報告では、戦後期に最も大規模な形で河川敷居住が見られた熊本・白川(一級河川、流域面積480km²)を事例に取り上げ、戦後の「河川敷」居住に対する行政(熊本市、熊本県、建設省)の対応を辿り、1970年代までそれが存続した要因について明らかにする。

著者

小川薫水 編

出版者

小川寳文館

巻号頁・発行日

1914

著者

設楽 薫

出版者

公益財団法人 史学会

雑誌

史学雑誌 (ISSN:00182478)

巻号頁・発行日

vol.96, no.7, pp.1142-1159,1255-, 1987-07-20 (Released:2017-11-29)

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Historians specializing in Muromachi politics during the rein of the 10th shogun Ashikaga Yoshiki 足利義材 have thus far focused their attention on his banishment in 1493 (the Meio Incident), which resulted in the assumption of power by the Hosokawa family. Very little interest, however, has been shown toward the problem of Yoshiki's shogunal governance itself. By analyzing the characteristics and background of Yoshiki's direct judgments (gozen sata 御前沙汰), the author attempts to redress this imbalance and also to improve our understanding of the actual status of Yoshiki's reign. The shogun's direct judgments were usually recorded in the ukagaigoto kiroku 伺事記録, a record kept by the officials who screened matters for the shogun's approval. The record for 1490 and related documents illuminate the shifts in procedure and personnel affairs after the Onin War. The judgment process originally took place only in the presence of the shogun, but Yoshiki always received applications and transmitted his decisions through a rapporteur (moshitsugi 申次). Two reasons for this change can be adduced : (1)the new process provided an effective means of dealing with the increasing number of suits and applications, regardless of when the next shogunal audience was scheduled or what personnel were on duty ; and (2)the shogun's cloistered father, Yoshimi, exercised the real power within the administration, although he had himself never been shogun. The rapporteurs were selected from among those long-term confidents of Yoshimi and Yoshiki, such as HAMURO Mitsutada 葉室光忠, TANEMURA Gyobu 種村刑部 and ISSIKI Jibu 一色治部. Yoshimi and his son lacked confldent retainers within the court at the time of Yoshiki's succession, because Yoshimi had been the very leader of anti-shogun Western force during the Onin War (1467-1477). Yoshimi and Yoshiki therefore tended to place greater trust in their long-term confidents than in those who newly came into service at Yoshiki's court. As close retainers these rapporteurs were entrusted with supervising matters involving the shogun's direct judgment. The shogun's liege vassals can be divided into the three categories : (1)those who had served with him before the Onin War, that is, men who were not hereditary servants of the bakufu ; (2)those who came to serve under Yoshimi during the Onin War ; and (3)those who came into service after Yoshiki's succession. Most of the persons whose names came up in gozen sata documents represented categories (1) and (2). Shogunal confidence in them was 'high' but his reliance on them inevitably led to feelings of estrangement on the part of hereditary servants of the bakufu. This, in turn, hastened the decline of Yoshiki himself in the Meio Incident.