著者

石岡 卓也 米田 貴雄 吉井 伸一郎 古川 正志

出版者

日本知能情報ファジィ学会

雑誌

知能と情報 (ISSN:13477986)

巻号頁・発行日

vol.19, no.6, pp.680-688, 2007-12-15 (Released:2008-03-17)

参考文献数

17

被引用文献数

2

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本研究は,実社会の情報伝播の一部分を成すブログ上の情報伝播に着目し,その特性として特に重要であると考えられる情報伝播規模がどのように分布するか,またその分布を決定付ける要因が何であるかを明らかにすることを目的とする.そのため,実ネットワークで観測したブログ上における情報伝播の規模分布の結果と,その数理モデルによる結果を比較し,適切なモデルを得る.情報伝播の規模は,トラックバックの連鎖によって情報が幾つのエントリへ伝播したかを採用した.数理モデルとしては複雑ネットワーク上のパーコレーションを適用した.結果として,ブログ上の情報伝播規模は,スケールフリーネットワーク上のパーコレーションと類似することが分かった.

著者

Mikio ISHIWATARI

出版者

兵庫県立大学 政策科学研究所

雑誌

Japan Social Innovation Journal (ISSN:21859493)

巻号頁・発行日

vol.6, no.1, pp.15-26, 2016-03-31 (Released:2016-05-05)

参考文献数

33

被引用文献数

11

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Flooding has become a serious issue in rapidly urbanizing countries. It is widely recognized that flood damages in urban areas can be decreased by taking an integrated risk management approach. This approach, however, has not been realized easily in major cities in Asia. The purpose of this paper is to examine the crucial issues in adopting the integrated approach to developing countries. It reviews Japanese experience and lessons of managing urban flood risks, and compares these lessons with situations in developing countries. It was found that establishing coordination mechanisms among a wide range of sectors is a crucial challenge. Furthermore, the paper proposes practical methods of promoting the integrated approach for urban flood risk management in developing countries.

著者

山本 一治

出版者

国立研究開発法人 科学技術振興機構

雑誌

情報管理 (ISSN:00217298)

巻号頁・発行日

vol.59, no.3, pp.200-202, 2016-06-01 (Released:2016-06-01)

著者

Tomoyoshi DOKI Tomomi TAKANO Tsutomu HOHDATSU

出版者

公益社団法人 日本獣医学会

雑誌

Journal of Veterinary Medical Science (ISSN:09167250)

巻号頁・発行日

pp.16-0020, (Released:2016-06-04)

被引用文献数

1

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Feline infectious peritonitis (FIP) is a fatal inflammatory disease caused by FIP virus infection. Feline tumor necrosis factor (fTNF)-alpha is closely involved in the aggravation of FIP pathology. We previously described the preparation of neutralizing mouse anti-fTNF-alpha monoclonal antibody (mAb 2–4) and clarified its role in the clinical condition of cats with FIP using in vitro systems. However, administration of mouse mAb 2–4 to cat may lead to a production of feline anti-mouse antibodies. In the present study, we prepared a mouse-feline chimeric mAb (chimeric mAb 2–4) by fusing the variable region of mouse mAb 2–4 to the constant region of feline antibody. The chimeric mAb 2–4 was confirmed to have fTNF-alpha neutralization activity. Purified mouse mAb 2–4 and chimeric mAb 2–4 were repeatedly administered to cats, and the changes in the ability to induce feline anti-mouse antibody response were investigated. In the serum of cats treated with mouse mAb 2–4, feline anti-mouse antibody production was induced, and the fTNF-alpha neutralization effect of mouse mAb 2–4 was reduced. In contrast, in cats treated with chimeric mAb 2–4, the feline anti-mouse antibody response was decreased compared to that of mouse mAb 2–4-treated cats.

著者

井坂 理穂

出版者

日本南アジア学会

雑誌

南アジア研究 (ISSN:09155643)

巻号頁・発行日

vol.2010, no.22, pp.313-326, 2010-12-15 (Released:2011-09-06)

参考文献数

40

著者

舩橋 惠子

出版者

日本社会学会

雑誌

社会学評論 (ISSN:00215414)

巻号頁・発行日

vol.65, no.1, pp.147-149, 2014 (Released:2015-07-04)

著者

Akihiro Okamoto Yoshihide Tokunou Junki Saito

出版者

一般社団法人 日本生物物理学会

雑誌

Biophysics and Physicobiology (ISSN:21894779)

巻号頁・発行日

vol.13, pp.71-76, 2016 (Released:2016-05-27)

参考文献数

32

被引用文献数

11

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Outer-membrane c-type cytochrome (OM c-Cyt) complexes in several genera of iron-reducing bacteria, such as Shewanella and Geobacter, are capable of transporting electrons from the cell interior to extracellular solids as a terminal step of anaerobic respiration. The kinetics of this electron transport has implications for controlling the rate of microbial electron transport during bioenergy or biochemical production, iron corrosion, and natural mineral cycling. Herein, we review the findings from in-vivo and in-vitro studies examining electron transport kinetics through single OM c-Cyt complexes in Shewanella oneidensis MR-1. In-vitro electron flux via a purified OM c-Cyt complex, comprised of MtrA, B, and C proteins from S. oneidensis MR-1, embedded in a proteoliposome system is reported to be 10- to 100-fold faster compared with in-vivo estimates based on measurements of electron flux per cell and OM c-Cyts density. As the proteoliposome system is estimated to have 10-fold higher cation flux via potassium channels than electrons, we speculate that the slower rate of electron-coupled cation transport across the OM is responsible for the significantly lower electron transport rate that is observed in-vivo. As most studies to date have primarily focused on the energetics or kinetics of interheme electron hopping in OM c-Cyts in this microbial electron transport mechanism, the proposed model involving cation transport provides new insight into the rate detemining step of EET, as well as the role of self-secreted flavin molecules bound to OM c-Cyt and proton management for energy conservation and production in S. oneidensis MR-1.

著者

永井 正勝

出版者

一般社団法人 日本オリエント学会

雑誌

オリエント (ISSN:00305219)

巻号頁・発行日

vol.43, no.1, pp.19-39, 2000-09-30 (Released:2010-03-12)

参考文献数

27

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The main subject of Middle Egyptian studies should be to seek its “langue” through careful analysis of the instances of “parole.” But many Egyptologists, such as Erman, Sethe, and Gardiner, did not fully recognize the importance of the “langue” of Middle Egyptian, instead they paid great attention to the study of morphological differences in the instances of “parole” themselves, and adapted the Semitic system to these differences. From the point of linguistics, however, morphological studies that are separated from the “langue” may possibly lead to misunderstandings of language.It was the linguist Hans Jakob Polotsky who first established the Middle Egyptian “langue” system through the analysis of grammatical categories and syntax. The German scholar Friedrich Junge also developed his grammatical study based on syntax and the “transformationsgrammatik” of Chomsky. By so doing, Polotsky and Junge disproved of the old-fashioned method of the Egyptologists' “Morphological Grammar, ” but there are also differences in the understanding of Middle Egyptian sentence system between Polotsky and Junge. Despite these differences, Leo Depuydt combined these two distinct studies and gave them the label “Standard theory.” Nowadays many scholars regard Polotsky's Idea as “Standard theory” according to Depuydt's terminology. It must be noted, however, that such a label is quite unsatisfactory since “Standard theory” does not equal to Polotsky's Idea, and that the very main point of Polotsky's Idea has been neglected by using such an unfortunate label. It is now clear that the subject with which we must grapple is to clarify the main point of Polotsky's Idea.In this paper I will examine Polotsky's Idea and point out the following Middle Egyptian sentence system explained by Polotsky. 1) There is a distinction of mode in Middle Egyptian. 2) The indicative mode of the main sentence is introduced by an auxiliary and has three tenses (i. e., present, past, future). 3) Some of the main sentences of indicative mode (1st tenses) have their counterparts in the emphasized adverbial sentences (2nd tenses). 4) The emphasized adverbial sentences in initial position (2nd tenses) begin with bare sdm. f/sdm. f form. 5) The prospective mode in the main sentence is expressed by bare sdm. f form.

出版者

国立研究開発法人 科学技術振興機構

雑誌

情報管理 (ISSN:00217298)

巻号頁・発行日

vol.59, no.3, pp.204-205, 2016-05-01 (Released:2016-06-01)

著者

山本 哲也 長谷川 香子 小野田 誠 田中 啓一

出版者

公益社団法人 日本薬学会

雑誌

YAKUGAKU ZASSHI (ISSN:00316903)

巻号頁・発行日

vol.136, no.6, pp.905-911, 2016 (Released:2016-06-01)

参考文献数

13

被引用文献数

1 7

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Iguratimod (IGU), a disease-modifying antirheumatic drug launched in September 2012, has been reported to carry a risk of severe hemorrhages through a suspected interaction with warfarin (WF) in the all-case surveillance and early postmarketing-phase vigilance. To elucidate possible mechanisms of adverse interaction between IGU and WF, we analyzed the effects of IGU on the pharmacodynamics and pharmacokinetics of WF in rats. IGU was orally administered to male Wistar rats once daily for 5 d at 10 or 30 mg/kg in combination with WF at an oral dose of 0.25 mg/kg. Coadministration of IGU 30 mg/kg enhanced the anticoagulant activity of WF; prolonged blood coagulation time (prothrombin time and activated partial thromboplastin time) and decreased levels of vitamin K (VK)-dependent blood coagulation factors (II, VII, IX, and X) were observed. On the other hand, the pharmacokinetic parameters of WF including maximum plasma concentration (Cmax) and area under the plasma concentration-time curve from 0 to 24 h (AUC0-24 h) were not affected by the combination with IGU. IGU alone did not change blood coagulation time at doses up to 100 mg/kg, while VK-dependent blood coagulation factors decreased slightly at 30 and 100 mg/kg. These results suggest that the pharmacodynamic effect of IGU on VK-dependent blood coagulation factors is involved in the mechanism of drug-drug interaction of IGU with WF.

著者

熊本 博光 西原 修 平岡 敏洋

出版者

公益社団法人 精密工学会

雑誌

精密工学会誌 (ISSN:09120289)

巻号頁・発行日

vol.68, no.5, pp.681-686, 2002-05-05 (Released:2009-04-10)

参考文献数

6

被引用文献数

1 2

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This paper considers salt water fishing tackles consisting of line, hook, bar float, primary sinker and secondary sinkers. The line with the sinkers and the hook are modeled by a multilink system connected with the float. A new algorithm is proposed to calculate acceleration terms satisfying Newtonian kinematical equations. The computational requirement varies only linearly with the number of links because the algorithm is based on a sweep-out operation on a threefold diagonal matrix with a simple structure. A comparison is made with a well-known Featherstone algorithm that is based on articulated body inertias. Animation results with 22 links subjected to tidal flow and wave produce typical tackle behaviors consistent with expert experience. The animation is useful for design of tackles and discrimination drills of fish hits.

著者

川野 恭雅 仲村 佳彦 村井 映 田中 潤一 西田 武司 水沼 真理子 大田 大樹 石倉 宏恭

出版者

一般社団法人 日本集中治療医学会

雑誌

日本集中治療医学会雑誌 (ISSN:13407988)

巻号頁・発行日

vol.23, no.3, pp.313-317, 2016-05-01 (Released:2016-05-02)

参考文献数

11

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二次性腎性尿崩症の治療の一つにインドメタシンがある。今回,我々は原因薬剤としてリチウムが疑われた腎性尿崩症に対し,高用量のインドメタシンが奏功した症例を経験したので報告する。症例は35歳の女性,双極性障害に対し17年間リチウムを服用していた。フェノバルビタールおよびクロルプロマジンの急性中毒のため当院へ搬送となった後,第2病日より450 ml/hrを超える多尿と血清Na値上昇を来し,バソプレシンに無反応であったため,二次性腎性尿崩症と診断した。病歴より原因薬剤としてリチウムが疑われ,治療としてインドメタシン150 mg/dayを投与したが効果がなかった。多尿に伴いcreatinine clearanceが亢進してインドメタシンの薬物血中濃度が低下している可能性を考慮し,インドメタシンを225 mg/dayまで増量したところ,尿量減少および血清Na値の低下を認めた。高用量のインドメタシンは二次性腎性尿崩症に対し,有効な治療法である可能性が示唆された。

著者

松沢 武雄

出版者

公益社団法人 土木学会

雑誌

地震工学研究発表会講演概要 (ISSN:09134085)

巻号頁・発行日

vol.2, pp.43-46, 1957 (Released:2010-06-04)

著者

山本 将功 中島 敦司 吉田 尚美 重藤 大地 加藤 万季

出版者

日本森林学会

雑誌

日本森林学会大会発表データベース 第117回 日本森林学会大会

巻号頁・発行日

pp.502, 2006 (Released:2006-03-15)

著者

坂 幸夫

出版者

日本社会学会

雑誌

社会学評論 (ISSN:00215414)

巻号頁・発行日

vol.59, no.1, pp.257-259, 2008-06-30 (Released:2010-04-01)

著者

落合 照雄

出版者

日本陸水学会

雑誌

日本陸水学会 講演要旨集 日本陸水学会第69回大会 新潟大会

巻号頁・発行日

pp.34, 2005 (Released:2005-09-21)

著者

小口 高 斉藤 享治 原 美登里 門村 浩 林 舟

出版者

公益社団法人 東京地学協会

雑誌

地学雑誌 (ISSN:0022135X)

巻号頁・発行日

vol.109, no.1, pp.120-125, 2000-02-25 (Released:2010-10-13)

参考文献数

18

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Data for Japanese alluvial fans have been made available on the Internet using ArcView IMS, a GIS-based map server software package. This system permits easy on-line browsing of the data from anywhere in the world and the creation of thematic maps at various scales for the area around an alluvial fan.

著者

佐藤 明

出版者

一般社団法人 日本機械学会

雑誌

日本機械学会論文集 B編 (ISSN:03875016)

巻号頁・発行日

vol.61, no.583, pp.933-938, 1995-03-25 (Released:2008-03-28)

参考文献数

15

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The object of the present study is to evaluate the performances of various microcanonical molecular dynamics algorithms. To do so, the divergence times and energy fluctuations are discussed for a model system, i. e. a three-dimensional Lennard-Jones system under various conditions of number densities and temperatures. The results of the evaluations of superiority or inferiority of algorithms are as follows. The velocity Verlet, leapfrog, and Beeman algorithms are significantly superior to the other algorithms such as the 4-value Gear algorithm since a system does not diverge and the energy conservation law is reasonably satisfied for much larger time intervals. Although these three algorithms show approximately the same performance concerning the properties of divergence times and energy fluctuations, we can conclude that the velocity Verlet algorithm is the most suitable for molecular dynamics simulations of flow problems, since this algorithm is easy to use, requires less computer memory, and evaluates molecular positions and velocities at the same time steps.

著者

軽米 克尊 酒井 利信

出版者

日本武道学会

雑誌

武道学研究 (ISSN:02879700)

巻号頁・発行日

vol.47, no.3, pp.119-138, 2015-03-31 (Released:2016-03-31)

参考文献数

29

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The aim of this study is to clarify as much as possible the process of formation of the Jikishinkage-ryū, and by comparing that to the lineage and transmission from after its formation, to show how it has changed. Specifically, we verified whether the lineage and transmission mentioned in the scrolls written after the Jikishinkage-ryū’s formation agree with those in the formation process. First, we examined the lineage and transmission in the scrolls written after the formation of Jikishinkage-ryū, and analyzed the formation process to clarify rewritten points in its lineage. We clarified the following six points:1.Yamada Heizaemon Mitsunori referred to himself as the second generation head of Jikishinseitō-ryū, not Jikishinkage-ryū. Therefore, it is after Naganuma Shirōzaemon Kunisato that Jikishinseitō-ryū was renamed Jikishinkage-ryū. This means there is a discrepancy between the period of the Jikishinkage-ryū’s formation and its transmission.2.Multiple discrepancies regarding names and meanings can be spotted between historical materials written by the people mentioned in the lineage of Jikishinkage-ryū, and the transmission mentioned in the scrolls written after Jikishinkage-ryū was formed. This indicates that parts of the transmission were rewritten after the formation of Jikishinkage-ryū.3.It is in the “Jikishinkage-ryū Mokuroku Kudensh” (Catalogue of techniques and oral transmission of Jikishinkage-ry) by Naganuma Shirōzaemon Kunisato that Matsumoto Bizen-no-Kami was first recognized as the founder of Jikishinkage-ryū.4.The Enpi kata of Shinkage-ryū that originates from Kage-ryū can also be confirmed in the catalogue of techniques of Shinshinkage-ryū, although written with different kanji. Therefore, Shinshinkage-ryū can be said to have been affected by Kage-ryū via Shinkage-ryū.5.The name and meaning of each school (ryū) found in the lineage of Jikishinkage-ryū were interpreted with the consideration that the tradition bestowed by the deity of martial arts was inherited from generation to generation. This was from Matsumoto Bizen-no-Kami, the founder, to Yamada Heizaemon Mitsunori, who changed the name of the school to Jikishinkage-ryū.6.It is after Naganuma Shirōzaemon Kunisato that the colophon “Kashima Shinden,” which shows that the style was bestowed by the deity Takemikazuchi, started to be used. It is also after Kunisato that Takemikazuchi was recognized as the originator of the school.

著者

隈崎 渡

出版者

法制史学会

雑誌

法制史研究 (ISSN:04412508)

巻号頁・発行日

vol.1957, no.7, pp.261-262, 1957-03-30 (Released:2009-11-16)