著者

Hirotaka YANAGAWA Hitoshi HATAI Takahiro TAODA Hassadin BOONSRIROJ Kazunori KIMITSUKI Chun-Ho PARK Toshifumi OYAMADA

出版者

公益社団法人 日本獣医学会

雑誌

Journal of Veterinary Medical Science (ISSN:09167250)

巻号頁・発行日

pp.14-0097, (Released:2014-03-26)

被引用文献数

1 9

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An 11-year-old mixed breed dog was presented with signs of anorexia. Radiographic and ultrasound examination revealed a large mass in the heart, between the right atrium and the right ventricle. Upon gross inspection, a multilobulated tumor arising from the right atrial wall and occupying the right atrium was identified. Microscopical analysis demonstrated that this tumor consisted of neoplastic cells with granular cytoplasm, which were separated into nests by fine fibrovascular stroma, and was negative for Grimelius’s method. Immunohistochemical examinations revealed that the neoplastic cells expressed chromogranin A, synaptophysin and neuron specific enolase. Electron microscopy revealed that the cytoplasm of the neoplastic cells held secretory granules. Based on these pathological findings, the tumor was diagnosed as a paraganglioma. This report is a rare case of primary paraganglioma deriving from the right atrium and provides a detailed characterization of its morphological features.

著者

和田森 直 石原 康利

出版者

公益社団法人 日本生体医工学会

雑誌

生体医工学 (ISSN:1347443X)

巻号頁・発行日

vol.49, no.1, pp.220-225, 2011-02-10 (Released:2011-12-13)

参考文献数

31

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A measurable depth of the blood glucose level by using photoacoustic spectroscopy (PAS) was discussed experimentally in order to improve detection sensitivity. Since a measurable depth of the PAS based on a modulation frequency of the chopped light irradiated to a sample, the relationship between modulation frequency and the thickness of a sample was evaluated. In our experiments, the photoacoustic detector consisted of an acoustic resonant pipe and an optical microphone, and a two-layer model composed of silicone sheets with the different optical absorption were used. We varied the thickness of the upper-layer for the two-layer model from 0.50 to 5.00 mm at each modulation frequencies to investigate the relationship between the measurable depth and the modulation frequency. As results, it is shown that the measurable depth was 2-3 mm with modulation frequency of 1.6-1.9 kHz. Furthermore, the reason for the measurable depth to be deeper than the thermal diffusion length of a sample was discussed. From these analyses of thermoelastic wave, the relation between the photoacoustic signal propagation and the measurable depth in a tissue was clarified.

著者

Michiya Matsusaki

出版者

(社)日本化学会

雑誌

Bulletin of the Chemical Society of Japan (ISSN:00092673)

巻号頁・発行日

vol.85, no.4, pp.401-414, 2012-04-15 (Released:2012-04-15)

参考文献数

53

被引用文献数

28

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The creation of artificial three-dimensional (3D) tissues possessing structure and function similar to natural tissue is a key challenge for implantable tissues in tissue engineering, and for model tissues in pharmaceutical assays. This account is a summary of our current research toward this challenge. We have developed a simple and unique bottom-up approach, hierarchical cell manipulation technique, using nanometer-sized layer-by-layer films consisting of fibronectin and gelatin (FN–G) as a nano-extracellular matrix (nano-ECM). The FN–G nanofilms were prepared directly on the cell surface, and we discovered that at least 6 nm thick FN–G films acted as a stable adhesive surface for adhesion of the second cell layer. Various 3D-layered constructs consisting of single or multiple types of cells were successfully fabricated, and the higher cellular activities induced from the 3D-structures as compared to monolayer structure were observed. Furthermore, the multilayered constructs like a blood vessel wall structure indicated almost the same drug response as in vivo natural blood vessels, suggesting the possibility to use as an in vitro blood vessel model to analyze drug response. Recently, we also developed a rapid bottom-up approach by a single cell coating using FN–G nanofilms, because the fabrication of two-layers (2L) is limited through the above technique due to the time required for stable cell adhesion. This rapid approach easily provided approximately eight-layered (8L) 3D-tissues after only one day of incubation. The layer number, cell type, and location were all successfully controlled by altering the seeding cell number and order. Moreover, fully and homogeneously vascularized tissues of 1 cm width and 50 µm height were obtained by a sandwich culture of the endothelial cells. These hierarchical cell manipulations will be promising to achieve one of the dreams of biomedical field, in vitro creation of artificial 3D-tissue models.

著者

高野 敦 松林 三和子 松田 淑男 小畑 貴稔 森川 洋

出版者

一般社団法人 日本機械学会

雑誌

日本機械学会論文集A編 (ISSN:18848338)

巻号頁・発行日

vol.79, no.804, pp.1201-1209, 2013 (Released:2013-08-25)

参考文献数

13

被引用文献数

1 2

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Long-term measurement and prediction for Ti-6Al-4V and A286 bolts was conducted. It was pointed out that Ti-6Al-4V indicates significant creep behavior and accumulated large creep strain and thus Ti-6Al-4V can not be applied for preloaded bolts. In addition, preload relaxation due to creep of solid-film lubricants for bolts and fastened aluminum parts were also pointed out. Recently, the authors developed a high strength bolted fastening system for satellite structures with PTFE (polytetrafluoroethylene) solid film lubricated Ti-6Al-4V bolts and aluminum threadedand drilled-hole parts. The authors, hence, measured the preload of the fastening system for 253-days, predicted 30-years later preload, and confirmed that the preload reduction was not harmful.

著者

長谷川 隆明 西川 仁 今村 賢治 菊井 玄一郎 奥村 学

出版者

一般社団法人 人工知能学会

雑誌

人工知能学会論文誌 (ISSN:13460714)

巻号頁・発行日

vol.25, no.1, pp.133-143, 2010 (Released:2010-01-06)

参考文献数

16

被引用文献数

2

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Recently, web pages for mobile devices are widely spread on the Internet and a lot of people can access web pages through search engines by mobile devices as well as personal computers. A summary of a retrieved web page is important because the people judge whether or not the page would be relevant to their information need according to the summary. In particular, the summary must be not only compact but also grammatical and meaningful when the users retrieve information using a mobile phone with a small screen. Most search engines seem to produce a snippet based on the keyword-in-context (KWIC) method. However, this simple method could not generate a refined summary suitable for mobile phones because of low grammaticality and content overlap with the page title. We propose a more suitable method to generate a snippet for mobile devices using sentence extraction and sentence compression methods. First, sentences are biased based on whether they include the query terms from the users or words that are relevant to the queries, as well as whether they do not overlap with the page title based on maximal marginal relevance (MMR). Second, the selected sentences are compressed based on their phrase coverage, which is measured by the scores of words, and their phrase connection probability measured based on the language model, according to the dependency structure converted from the sentence. The experimental results reveal the proposed method outperformed the KWIC method in terms of relevance judgment, grammaticality, non-redundancy and content coverage.

出版者

一般社団法人日本体力医学会

雑誌

体力科学 (ISSN:0039906X)

巻号頁・発行日

vol.40, no.2, pp.246-250, 1991-04-01 (Released:2010-09-30)

著者

杉村 久理 神代 雅晴 赤築 秀一郎 戸上 英憲 泉 博之 岩下 丈太郎 高橋 雄三

出版者

一般社団法人 日本人間工学会

雑誌

人間工学 (ISSN:05494974)

巻号頁・発行日

vol.36, no.Supplement, pp.380-381, 2000-06-28 (Released:2010-03-12)

参考文献数

2

著者

Yusuke HORI Takatoshi OZAKI Yoshimitsu YAMADA Teruaki TOZAKI Heui-Soo KIM Ayaka TAKIMOTO Maiko ENDO Noboru MANABE Miho INOUE-MURAYAMA Kazuo FUJITA

出版者

日本ウマ科学会

雑誌

Journal of Equine Science (ISSN:13403516)

巻号頁・発行日

vol.24, no.3, pp.31-36, 2013 (Released:2013-09-30)

参考文献数

15

被引用文献数

2 12

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Genetic polymorphisms in genes related to neurotransmitters or hormones affect personality or behavioral traits in many animal species including humans. In domestic animals, the allele frequency of such genes has been reported to be different among breeds and it may account for breed differences in behavior. In this study, we investigated breed differences in horses in the dopamine receptor D4 gene (DRD4), which has been reported to affect horse personality. We collected samples from seven horse breeds including those native to Japan and Korea, and compared the sequence of the DRD4 exon3 region among these breeds. We found that there were two types of polymorphisms (VNTR and SNPs) in the exon3 region, and some of them seemed to be breed-specific. In addition, we found that the allele frequency of G292A, reported to be associated with horse personality, differed greatly between native Japanese horses and Thoroughbred horses. The frequency of the A allele which is associated with low curiosity and high vigilance, was much lower in native Japanese horses (Hokkaido, 0.03; Taishu, 0.08) than in Thoroughbreds (0.62). This difference may account for breed differences in personality or behavioral traits. Further studies of the function of these polymorphisms and their effect on behavior are indicated.

著者

那須 義次 舘 卓司 梅澤 類 西浜 絢子 田中 寛

出版者

関西病虫害研究会

雑誌

関西病虫害研究会報 (ISSN:03871002)

巻号頁・発行日

vol.53, pp.91-92, 2011 (Released:2011-09-01)

参考文献数

7

著者

藤田 早苗 平 博順 永田 昌明

出版者

一般社団法人 言語処理学会

雑誌

自然言語処理 (ISSN:13407619)

巻号頁・発行日

vol.20, no.2, pp.223-250, 2013-06-14 (Released:2013-09-14)

参考文献数

26

被引用文献数

1

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既存のテキストのみからなる辞書に対し,インターネット上にある膨大な画像を関連付けることができれば,文字列情報からだけでは得られない,視覚的な情報を利用できるようになり,用途が広がると期待できる.そのため,本稿では,辞書の出来る限り広い語義に対して画像を付与することを考える.作成・維持コストを考えれば,なるべく自動的に画像を付与することが望ましいが,大量の辞書エントリに対して,高い精度で画像を付与することは容易ではない.また,そもそもどういった語義には画像を付与できるのか,あるいはできないのかといった調査が大規模になされた例はなく,画像が付与できる語義を自動的に判別することも困難である.そこで本稿では,まず語義別に画像が付与された辞書を人手で構築することを第一の目標とする.その上で,画像が付与できる語義とできない語義について,品詞や意味クラスとの関連性に着目して分析する.具体的には,名詞,動詞,形容詞,形容動詞,副詞を含む 25,481 語,39,251 語義を対象に画像付与実験と分析を行ない,その結果,全語義の 94.0% は画像付与が可能であること,品詞や意味クラスに応じて画像付与の可否が変わることを示す.また,幅広い語義に適切な画像を付与するため,インターネットから画像検索によって画像を獲得する.検索時に重要となるのが検索語である.本稿の第二の目標は,語義毎に適切な画像を得るための検索語を調査することである.本稿では,複数の検索語の組合せ(以下,検索語セット)の中から最も適切な画像を得られる検索語セットを作業者に選択してもらい,適切な検索語セットがない場合には修正してもらう.こうして最終的に利用された検索語セットを分析し,提案手法の改良点を探る.さらに,検索語セットの優先順位の決定方法も提案,その妥当性を示すことを本稿の第三の目標とする.新しい辞書への適用等を考えると,人手による画像付与ができない場合でも,優先順位の高い検索語セットによる検索結果が利用できれば,有用だと考えられるからである.提案手法では,対象語義がメジャーな語義かどうかで優先順位を変化させる.実験では,2 種類の評価方法を通してその妥当性を示す.

著者

吉川 克正 浅原 正幸 松本 裕治

出版者

一般社団法人 言語処理学会

雑誌

自然言語処理 (ISSN:13407619)

巻号頁・発行日

vol.20, no.2, pp.251-271, 2013-06-14 (Released:2013-09-14)

参考文献数

23

被引用文献数

4 6

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本稿ではマルコフロジックを利用した日本語述語項構造解析について述べる.日本語述語項構造解析に関する従来研究の多くは,格毎に独立した解析器を用意し,他の述語項関係との依存関係を無視したまま解析を行っていた.これに対し,本研究では同一文内にある全ての述語項候補を同時に考慮して解析する手法を提案する.この手法は複数の述語項関係の間にある依存関係を考慮した上で,文内における全ての述語項関係の候補から,最適な状態を見つけ出すことができる.さらに,本研究では,述語の項として妥当でないものを削除するための新たな論理的制約を考案し,ゼロ照応も含めて正しい項を効果的に見つけ出すことができるように工夫した.NAIST テキストコーパスにおける実験で,本研究の提案手法は,大規模データを利用せずに,従来手法と同等の結果を達成した.

著者

多田隈 建二郎 多田隈 理一郎 井岡 恭平 妻木 勇一

出版者

一般社団法人 日本ロボット学会

雑誌

日本ロボット学会誌 (ISSN:02891824)

巻号頁・発行日

vol.30, no.6, pp.611-620, 2012 (Released:2012-08-15)

参考文献数

25

被引用文献数

3

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As ordinary dual-axis driving mechanisms in X–Y directions, for example, commercially available X–Y stages with ball screws are familiar. However, such driving mechanisms have two stages, namely both upper and lower linear actuators, the latter of which must generate sufficient thrust to carry large weights, including that of the upper actuator mechanism, which has hampered efforts to achieve suitably fast and smooth driving motion due to the inertial force effect. It is also difficult to achieve a small and slimline driving mechanism with such overlapping two-stage structure. In these ordinary two-stage driving mechanisms, the motion of the X–Y stage can be disturbed by the cords of the upper actuator. In this research, we have considered the abovementioned problems, and propose a new omnidirectional driving gear mechanism that enhances its driving area from the normal X–Y plane to convex and concave curved surfaces respectively, and even various combinations of both. The smoothness of basic omnidirectional motion and effectiveness of the driving method of this proposed omnidirectional driving gear mechanism have been confirmed with several experiments involving our setups.

著者

多田隈 建二郎 広瀬 茂男

出版者

日本ロボット学会

雑誌

日本ロボット学会誌 (ISSN:02891824)

巻号頁・発行日

vol.25, no.3, pp.343-345, 2007-04-15 (Released:2010-08-25)

参考文献数

3

著者

植田 真一郎

出版者

一般社団法人 日本臨床薬理学会

雑誌

臨床薬理 (ISSN:03881601)

巻号頁・発行日

vol.39, no.5, pp.143-146, 2008 (Released:2009-02-05)

参考文献数

9

被引用文献数

1 1

著者

Sobi Asako Laurean Ilies Pritha Verma Saki Ichikawa Eiichi Nakamura

出版者

(社)日本化学会

雑誌

Chemistry Letters (ISSN:03667022)

巻号頁・発行日

pp.131205, (Released:2014-02-04)

被引用文献数

3

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A theoretical study on a tripodal alkoxydipshophine ligand (POP), which accelerates the nickel-catalyzed monosubstitution of a polyfluoroarene with an organozinc reagent, revealed that the alkoxy group and the diphosphine act independently to facilitate cooperation of a Lewis acid and a transition metal.

著者

朝日 稔 古屋 義男 呉 要翰 加瀬 信雄

出版者

日本哺乳類学会

雑誌

哺乳動物学雑誌: The Journal of the Mammalogical Society of Japan (ISSN:05460670)

巻号頁・発行日

vol.11, no.1-2, pp.65-70, 1986-05-10 (Released:2010-08-25)

参考文献数

4

著者

赤松 直樹

出版者

昭和大学学士会

雑誌

昭和医学会雑誌 (ISSN:00374342)

巻号頁・発行日

vol.71, no.6, pp.576-579, 2011-12-28 (Released:2012-08-03)

参考文献数

4

著者

Masaki Ogawa Motoo Nakagawa Masaki Hara Masato Ito Toshihiko Goto Nobuyuki Ohte Yuta Shibamoto

出版者

Annals of Thoracic and Cardiovascular Surgery 編集委員会

雑誌

Annals of Thoracic and Cardiovascular Surgery (ISSN:13411098)

巻号頁・発行日

vol.19, no.1, pp.46-48, 2013-02-20 (Released:2013-02-20)

参考文献数

5

被引用文献数

2 10

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We report a 64-year-old man with incidentally found uncorrected total anomalous pulmonary venous connection (TAPVC). There have been only a few case reports of untreated TAPVC diagnosed after 60 years of age. Also, this is a first case report of TAPVC in which ECG-gated CT and phase-contrast cine magnetic resonance imaging (PC-MRI) was performed. He was referred to our hospital for the surgery of rectal cancer. He had been diagnosed to have an arterial septal defect (ASD) and persistent left superior vena cava (PLSVC), and Eisenmenger’s syndrome was thought to be the cause of cyanosis at first. The vertical vein in TAPVC was initially misdiagnosed as PLSVC on enhanced axial CT images reconstructed with 5-mm slice thickness with gapless. ECG-gated CT and PC-MRI were useful to confirm the diagnosis. The vertical vein in TAPVC is morphologically similar to PLSVC. This kind of abnormality would be somewhat difficult to diagnose on non-ECG-gated CT, and might be misdiagnosed as a large ASD and PLSVC.

著者

石川 武

出版者

法制史学会

雑誌

法制史研究 (ISSN:04412508)

巻号頁・発行日

vol.2004, no.54, pp.259-266, 2005-03-30 (Released:2010-05-10)