著者
窪田 亮介 角熊 雅彦 辻本 聖直 濱田 裕之 柚木 大和
出版者
日本口腔診断学会
雑誌
日本口腔診断学会雑誌 (ISSN:09149694)
巻号頁・発行日
vol.33, no.2, pp.166-169, 2020 (Released:2020-07-22)
参考文献数
24

We report the extraction of a mandibular third molar with six roots. The patient was a woman in her twenties. She was referred to our hospital with the chief complaint of gingival swelling of the right mandibular third molar region. Impacted teeth with many roots were found by dental X-ray imaging. We diagnosed pericoronitis and extraction was performed under local anesthesia. Extraction was easy, and no fracture was observed in any of the roots. There were no postoperative complications. As seen by CT, the extracted teeth revealed 7 cusps and 6 roots with 5 root canals.
著者
宮本 顕二
出版者
一般社団法人 日本呼吸ケア・リハビリテーション学会
雑誌
日本呼吸ケア・リハビリテーション学会誌 (ISSN:18817319)
巻号頁・発行日
vol.6, no.3, pp.168-173, 1997-04-05 (Released:2019-10-15)
参考文献数
6

在宅酸素療法はわが国でもっとも成功した在宅医療であるだけでなく,慢性呼吸不全患者の予後改善に大きく貢献している.その普及においても米国諸国にひけをとらない現状である.しかし,今後は患者の生命予後をただ単に延長させるだけでなく,患者の生活の質をより一層向上させる施策を検討する時期にきている.
著者
鶴巻 萌 齋藤 元文 丸山 茂徳 金井 昭夫
出版者
公益社団法人 東京地学協会
雑誌
地学雑誌 (ISSN:0022135X)
巻号頁・発行日
vol.129, no.6, pp.881-898, 2020-12-25 (Released:2021-01-18)
参考文献数
49
被引用文献数
2 5

It is well known that the evolution of life is affected by environmental factors, and this should be a fundamental perspective when investigating the origin of life; however, this perspective has not been fully addressed in biology. The Hadean Earth had a completely different surface environment from that of today, with no free oxygen, but instead a local environment rich in H2 which was generated by serpentinization, while energy–material circulation was driven by nuclear geysers. It is proposed that an anoxic hot-spring environment, with abundant hydrogen produced by serpentinization, was the birthplace of life. It is also proposed that the Hakuba hot spring in Nagano, Japan, is a Hadean-Earth-like environment with an H2-rich environment. A microbe found there, designated Hakuba OD1, is a member of the Candidate Phyla Radiation (CPR) bacteria group. In this review, CPR bacteria are described and their importance for the origin of life is discussed. The CPR is a bacterial supergroup consisting of dozens of phylum-level lineages of very small bacteria. This group was recently discovered with a metagenomics analysis that allowed unculturable environmental samples to be detected. Biochemical approaches to the CPR bacteria have not yet been successful because almost all the bacteria are unculturable or have not been isolated. However, with the development of massive parallel sequencing technology (next-generation sequencing), the phylogenetic characteristics of the CPR bacteria are becoming clear, and genomic analyses of these bacteria have led to unique discoveries. The sizes of the CPR bacterial genomes range from 400 to 1,500 kilobases (kb), and they contain approximately 400-1,500 genes. Thus, their genomes are remarkably small compared to other well-known and ordinary bacteria, represented by Escherichia coli, which have over 4,000 genes, but are similar to those of symbiotic or parasitic bacteria. The CPR bacterial genomes also lack many of the genes involved in essential metabolic pathways, such as the tricarboxylic acid (TCA) cycle and amino acid biosynthesis, so they seem to obtain their essential metabolites from their environments. It is proposed that this knowledge is important when considering the chemical changes that occurred on primitive Earth, which gave rise to the first forms of life through the processes of chemical evolution. Therefore, it is essential to understand the kinds of protein that are encoded in CPR bacterial genomes when studying the origin of life.
著者
田中 鎮雄
出版者
日本武道学会
雑誌
武道学研究 (ISSN:02879700)
巻号頁・発行日
vol.13, no.3, pp.19-27, 1981-03-31 (Released:2012-11-27)
参考文献数
14

Change of value orientation about KENDO in the Course of Study for Secondary Schools and its manuals were investigated in Japan from 1913. The results were as follows:(1) The modern Japanese school KENDO was founded in 1911 at the end of the Meiji Era. At the beginning of that time, KENDO was involved in the options program and not involved in the Teaching Handbook.(2) The aims and contents of KENDO in the secondary schools were determined by the Ministry of Education and fully described in the Course of Study in 1936. At that time, the most important aims of KENDO was spiritual training for young people in school and its community.(3) Though KENDO and JUDO have gradually developed, as well as gymnastics and military drill in physical education program, they were regarded as more and more important at that time of the World War I and II. And at last, the spiritual and military training in KENDO, as well as other physical education program had stressed as the greatest of value orientations at that time of the War II.(4) Afer the War II, from 1953, the aims and contents of KENDO in the secondary schools have gradually developed as sport.(5) On the other hand, there seems to be no doubt that KENDO has left some value concerning the spiritual and physical training.
著者
星山 栄成
出版者
日本神経治療学会
雑誌
神経治療学 (ISSN:09168443)
巻号頁・発行日
vol.37, no.4, pp.508-512, 2020 (Released:2021-05-27)
参考文献数
28

Post–stroke epilepsy (PSE) is divided into two categories. Early seizures (ES) typically occur within one week after stroke onset and are also termed ‘acute symptomatic seizures’, whereas late seizures (LS) have a peak within 6–12 months with a higher recurrence rate. PSE is about 10% as a stroke complication, but its rate is as high as 30 to 40% in the cause of elderly–onset epilepsy. Although there is no evidence for the treatment of post–stroke epilepsy, antiepileptic drug treatment should be considered in the event of an unprovoked first seizure. We hope that new antiepileptic drugs will be effective as the evidence accumulates. This review provides a comprehensive perspective of PSE, including the definition, diagnostic criteria, examination tool, and treatment of PSE.
著者
尾原 知行 山本 康正 田中 瑛次郎 藤並 潤 森井 芙貴子 石井 亮太郎 小泉 崇 永金 義成
出版者
一般社団法人 日本脳卒中学会
雑誌
脳卒中 (ISSN:09120726)
巻号頁・発行日
vol.35, no.3, pp.167-173, 2013-05-20 (Released:2013-05-24)
参考文献数
14

要旨:【背景/目的】脳静脈血栓症は近年日常診療で遭遇する機会が増えている.脳静脈血栓症自験例の臨床像,急性期画像所見につき検討する.【方法】対象は2008年4月~2011年3月に当院に入院した脳静脈血栓症10例(平均49歳,男性5例/女性5例)である.【結果】初診時臨床症状は,7例で局所神経症状(うち5例は軽度の運動麻痺)を認め,3例は頭痛のみであった.4例はけいれん発作を伴った.閉塞静脈洞は上矢状洞6例,横静脈洞3例,直静脈洞1例で,初診時脳出血を4例,静脈梗塞を3例に認めた.9例で頭部MRI T2*強調画像にて閉塞静脈洞が低信号で強調された.全例抗凝固療法で治療し,8例は退院時modified Rankin Scale 0~1であった.【結論】自験10症例は比較的軽症で予後良好な例が多かった.T2*強調画像を含むMRI検査による早期診断が臨床経過に影響を与えている可能性が考えられた.
著者
田辺 信介
出版者
一般社団法人 日本生態学会
雑誌
日本生態学会誌 (ISSN:00215007)
巻号頁・発行日
vol.66, no.1, pp.37-49, 2016 (Released:2016-06-01)
参考文献数
41
被引用文献数
7

化学物質の中でヒトや生態系にとって厄介なものは、毒性が強く、生体内に容易に侵入し、そこに長期間とどまる物質であろう。こうした性質をもつ化学物質の代表に、PCBs(ポリ塩化ビフェニール)やダイオキシン類などPOPs(残留性有機汚染物質)と呼ばれる生物蓄積性の有害物質がある。筆者がPOPs の汚染研究を開始したのは1972 年のことで、テーマは「瀬戸内海のPOPs 汚染に関する研究」であった。当時の汚染実態はきわめて深刻化していたが、不思 議なことに瀬戸内海に残存しているPOPs 量は使用量に比べ予想外に少ないことに気がついた。この疑問は、「大気経由でPOPs が広域拡散したのではないか」という仮説を生み、地球汚染を実証する研究へと進展した。この研究の中で、ダイオキシン類やDDT は局在性が強く地域汚染型の物質であるが、PCBs や殺虫剤のHCHs は長距離輸送されやすい地球汚染型の物質であることを、大気や水質の調査だけでなく生物を指標とした研究でも明らかにした。また冷水域は、POPs の沈着の場となることを示唆した。さらに、POPs は食物連鎖を通して生物濃縮され高次の生物種ほど汚染が著しいこと、とくに海洋生態系の頂点にいる鯨類などの水棲生物は、体内にきわめて高い濃度のPOPs を蓄積していることが認められた。この要因として、この種の動物の体内に有害物質の貯蔵庫(皮下脂肪)が存在すること、授乳による母子間移行量が大きいこと、有害物質を分解する酵素系が一部欠落していること、などが判明した。以上の結果から、海棲哺乳動物はPOPs のハイリスクアニマルであることが示唆され、地球環境時代に相応しい環境観や社会観を醸成して生態系を保全する施策が必要なことを提言した。また、先進国だけでなく新興国や途上国でもPOPs 汚染は顕在化しており、今後さらに深刻化することが予想されるため、ストックホルム条約の適切な履行が求められる。