著者

Kazuyo TAIRA Toshimune NAGAI Takeshi OBI Kozo TAKASE

出版者

公益社団法人 日本獣医学会

雑誌

Journal of Veterinary Medical Science (ISSN:09167250)

巻号頁・発行日

vol.76, no.4, pp.583-586, 2014 (Released:2014-05-01)

参考文献数

22

被引用文献数

5 57

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Broiler chicks were reared on either wet litter or dry litter to compare the development of footpad dermatitis (FPD). Broilers reared on wet litter first developed FPD at 14 days of age. Their FPD scores increased sharply after 21 days of age, reaching 2.92 at 42 days. In broilers reared on dry litter, FPD was first observed at 28 days of age, and the FPD score was only 0.70 at 42 days. When 21- or 28-day-old broilers that had been reared on wet litter and had developed FPD were moved to dry litter, the progression of FPD was suppressed or delayed. These results suggest that reducing litter moisture is effective in preventing FPD and suppressing disease progression.

著者

塩見 卓 三宅 正男 平藤 哲司

出版者

一般社団法人 軽金属学会

雑誌

軽金属 (ISSN:04515994)

巻号頁・発行日

vol.63, no.6, pp.234-242, 2013-06-30 (Released:2013-09-30)

参考文献数

61

被引用文献数

3

著者

脇屋 裕一郎 勝木 宏昭 古田 祥知子 古川 敬通 坂井 隆宏

出版者

日本暖地畜産学会

雑誌

西日本畜産学会報 (ISSN:09143459)

巻号頁・発行日

vol.45, pp.45-50, 2002-07-01 (Released:2010-08-25)

参考文献数

7

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生物膜法による汚水処理施設の維持管理の簡易化及び低コスト化を図るため, 担体となる多孔質セラミックスを試作し, その処理能力を比較した.試験槽は, 水槽を用いて総容量61の汚水槽とし, そこに担体を40~50%充填した容器を設置し, エアポンプによる曝気処理を行った.担体は, 市販セラミックス, 低コストセラミックス, 軽石の3種類を用い, 試験区は, 市販セラミックスを対照区に, 以下セラミックス区, 軽石区とし、それぞれの区に担体充填率40%区と50%区を設けた.試験期間中の処理水の引き抜き及び汚水の投入量は, 1日1回11とし, 開始から約60日間は, BOD容積負荷を0.1~0.2kg/m3・dayの範囲で汚水投入を行いながら汚泥を形成させ, 測定期間中はBOD容積負荷を0.1~1.1kg/m3・dayの範囲で投入し, 試験に供した.試験の結果, 低コストセラミックスは, 気孔率で市販セラミックスと比較して低かったものの, 気孔径ではほぼ同等の結果が得られた.気孔率については各担体において終了時の減少が確認された.また, 試験期間中の担体重量減少率は, 軽石区が最も多く, セラミックス区が少なかった.処理能力について, BOD, SSは, 全ての試験区において高い浄化が確認されたが, T-Pは軽石区で低い結果となった.T-Nはセラミックス50%区, 対照50%区の順に, またNH4-Nは対照50%区が高い浄化が確認されたが, 対照区は充填率によるNH4-N除去率の差が高かった.CODについては, 対照40%区が最も高かったが, 試験区間における差はほとんど認められなかった.以上の結果より, 低コストセラミックスは, 市販セラミックスとほぼ同等の耐久性と浄化能力があることが示唆された.

著者

大森 暢久 岸 篤 岡部 五成 長田 宗憲 浅見 正彦 平山 雄

出版者

日本民族衛生学会

雑誌

民族衛生 (ISSN:03689395)

巻号頁・発行日

vol.25, no.5, pp.644-648,A40, 1959 (Released:2010-11-19)

参考文献数

6

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In order to investigate the actual state of cancer within the jurisdiction of the Kawagoe Helth Centre of the Saitama Prefecture, we have visited all the 110 hospitals and clinics within the jurisdiction, under the cooperation of the Doctors' Ass'n., and the Health Centre. We have not only inquired of the doctors, but have also gone through the protocols of the patients who have come during the investigation period, and we have chosen those who were diagnosed as cancer or malignant ulcer, making our observations according to sex, age, and disease types. We have calculated the death rate by comparing the contraction percentage of cancer, the prevalence rate, and the death certificate ; and have compared it with the figures of various parts of the U.S.A., and the Miyagi, Okayama, and Saitama Prefectures. Furthermore, the monthly survival rate was obtained, and the drawing up of basic data was attempted in order to devise measures of the prevention of cancer.

著者

Hiroko Ushikubo Yui Tanimoto Kazuho Abe Tomohiro Asakawa Toshiyuki Kan Tatsuhiro Akaishi

出版者

公益社団法人日本薬学会

雑誌

Biological and Pharmaceutical Bulletin (ISSN:09186158)

巻号頁・発行日

vol.37, no.5, pp.748-754, 2014-05-01 (Released:2014-05-01)

参考文献数

26

被引用文献数

2 11

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Amyloid β protein (Aβ) self-assembles into insoluble fibrils, and forms the senile plaques associated with Alzheimer’s disease. 3,3′,4′,5′-Tetrahydroxyflavone, a synthetic analogue of the natural flavonoid fisetin, has been found to potently inhibit Aβ fibril formation. In the present study, we investigated how inhibition of Aβ fibril formation by this flavonoid affects Aβ conformation and neurotoxicity. Sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE) analysis of Aβ1-42 (20 µM) incubated with or without 3,3′,4′,5′-tetrahydroxyflavone demonstrated that 3,3′,4′,5′-tetrahydroxyflavone (100 µM) rapidly caused formation of atypical Aβ conformers, which appeared as a very broad, smear-like band in the high molecular weight region and were distinguishable from soluble Aβ oligomers or mature Aβ fibrils. Transmission electron microscopy (TEM) revealed that large spherical Aβ aggregates were preferentially formed in the presence of 3,3′,4′,5′-tetrahydroxyflavone. The SDS-resistant, smear-like band on SDS-PAGE and the large spherical aggregates in TEM both disappeared after heat treatment (100°C, 10 min). Furthermore, a neurotoxicity assay with cultured rat hippocampal neurons demonstrated that Aβ incubated with 3,3′,4′,5′-tetrahydroxyflavone was significantly less toxic than Aβ incubated without the flavonoid. These results suggest that the newly synthesized fisetin analogue 3,3′,4′,5′-tetrahydroxyflavone directly produces atypical, large Aβ aggregates and reduces Aβ toxicity.

著者

笠置 遊 大坊 郁夫

出版者

公益社団法人 日本心理学会

雑誌

心理学研究 (ISSN:00215236)

巻号頁・発行日

vol.81, no.1, pp.26-34, 2010 (Released:2010-08-13)

参考文献数

33

被引用文献数

1 2

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This study examined how people can handle the multiple audience problem of self-presentation (Fleming, 1994), when faced with two or more audiences while simultaneously wanting each audience to form or maintain a different impression of the presenter. In the laboratory, female participants had a brief conversation with either an opposite-sex (male) or a same-sex (female) confederate. The results showed that when no one else observed the conversation, the participants presented themselves as physically attractive to the opposite-sex more than to the same-sex audience. On the other hand, when another same-sex individual was observing the conversation, the participants presented themselves to the opposite-sex audience as less physically attractive but more socially desirable and friendly. The importance of this compensatory self-enhancement strategy in the multiple-audience situation is discussed.

著者

石田 裕

出版者

一般社団法人 日本調理科学会

雑誌

日本調理科学会誌 (ISSN:13411535)

巻号頁・発行日

vol.29, no.2, pp.160-165, 1996-05-20 (Released:2013-04-26)

参考文献数

9

著者

四宮 陽子

出版者

一般社団法人 日本調理科学会

雑誌

日本調理科学会誌 (ISSN:13411535)

巻号頁・発行日

vol.33, no.2, pp.198-203, 2000-05-20 (Released:2013-04-26)

参考文献数

8

被引用文献数

4

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The textural properties of noodles boiled and kept in a refrigerator for 0,1,2 and 4 hours and 1 day were investigated by a breaking test. The curve of the breaking stress was analyzed by difference calculus to indicate the degree of the change in hardness while chewing the noodles. The change in texture, or koshi, of the noodles after boiling could be quantitatively expressed by the change in slope of the breaking stress curve with a strain of 0.01. A multiple-regression analysis of the noodle texture was performed on the score from the sensory evaluation and the breaking test results. The breaking energy and the discrepancy in the slope of the breaking stress curve for the noodles were selected as independent variables, and the multiple correlation coefficient was 0.997.

出版者

公益社団法人 日本農芸化学会

雑誌

化学と生物 (ISSN:0453073X)

巻号頁・発行日

vol.8, no.9, pp.548-549, 1970-09-25 (Released:2009-05-25)

著者

高木 和子

出版者

国立研究開発法人 科学技術振興機構

雑誌

情報管理 (ISSN:00217298)

巻号頁・発行日

vol.45, no.9, pp.643-648, 2002 (Released:2002-12-01)

参考文献数

15

出版者

日本鉱物科学会

雑誌

岩石鉱物鉱床学会誌 (ISSN:00214825)

巻号頁・発行日

vol.71, no.3, pp.79-92, 1976 (Released:2012-07-13)

著者

松村 保広

出版者

日本DDS学会

雑誌

Drug Delivery System (ISSN:09135006)

巻号頁・発行日

vol.28, no.3, pp.215-220, 2013-07-25 (Released:2013-10-25)

参考文献数

12

被引用文献数

1

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ナノテクノロジーを駆使したDDS系薬剤が次々と承認されてきている。ミセル製剤に関しては国立がん研究センターを中心にして、国内外において、いくつかの治験がはしっており、ミセル製剤の臨床的な有用性が期待されている。本章では、特に、タキソール内包ミセルNK105、シスプラチン内包ミセルNC-6004、エピルビシン内包ミセルNC-6300の臨床開発の状況につき概説する。

著者

Masahumi Johkan Asami Nagatsuka Ayako Yoshitomi Takuya Nakagawa Toru Maruo Satoru Tsukagoshi Masa-aki Hohjo Na Lu Akio Nakaminami Kazuo Tsuchiya Yutaka Shinohara

出版者

園芸学会

雑誌

Journal of the Japanese Society for Horticultural Science (ISSN:18823351)

巻号頁・発行日

pp.CH-096, (Released:2014-05-03)

被引用文献数

1 12

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To produce tomato fruits with 6% average Brix without decreasing yield, we investigated the effect of moderate salinity stress on Brix and yield in a single-truss, high-density tomato production system. Because tomato fruit development can be predicted from cumulative temperature, we also assessed cumulative temperature after anthesis as a potential indicator for determining the starting points of salinity stress treatments. When transverse diameters of the first fruit reached 4 cm (i.e., early increase treatment) or the first fruits were at the mature green stage (i.e., late increase treatment), nutrient solution electrical conductivity was slowly increased until the breaker stage from 1.8 dS·m−1 to 6.0 dS·m−1. Plants subjected to the late increase treatment produced tomato fruits with Brix values of 6% without reductions in marketable yield. We also increased nutrient solution electrical conductivity based on cumulative temperature after anthesis and found that early-treated plants produced tomatoes with higher Brix levels and yields than late-treated plants. In summary, moderate salinity stress to avoid excessive stress on plants increased sugar concentrations without decreasing fruit yield and resulted in tomato fruits with average Brix of about 6% when nutrient solution electrical conductivity was increased at a rate of 0.1 dS·m−1·day−1. Because seasonal differences in cumulative temperature influence the appropriate timing of salinity stress applications, further study is needed to optimize year-round growth under moderate salinity stress in single truss, high-density tomato production systems.

著者

Tatsuya Yamamoto Shoji Shinamura Eigo Miyazaki Kazuo Takimiya

出版者

(社)日本化学会

雑誌

Bulletin of the Chemical Society of Japan (ISSN:00092673)

巻号頁・発行日

vol.83, no.2, pp.120-130, 2010-02-15 (Released:2010-02-15)

参考文献数

40

被引用文献数

59

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In order to gain an insight into the relationship between the molecular structure and the semiconductor characteristics of highly π-extended heteroarene-based organic semiconductors, three structural isomers of dinaphthothieno[3,2-b]thiophenes with C2h symmetry were investigated. Of these, two isomers, dinaphtho[2,1-b:2′,1′-f ]thieno[3,2-b]thiophene (2) and dinaphtho[1,2-b:1′,2′-f ]thieno[3,2-b]thiophene (3), were newly synthesized, characterized, and utilized as active semiconducting layers in organic field-effect transistors (FETs). Detailed investigation of the physicochemical properties of 2 and 3, together with another isomer, dinaphtho[2,3-b:2′,3′-f ]thieno[3,2-b]thiophene (1), indicated that the electronic structures of the three isomers are fairly different from each other despite having the same molecular formula and the same aromatic constituents. Comparison of the molecular arrangements in the crystals elucidated by X-ray structural analysis implied that the molecular shape and the thus-induced favorable intermolecular interactions play important roles in determining the entire molecular arrangement. The characteristics of 2- and 3-based FETs with maximum field-effect mobilities (μFET s) of 10−3–10−2 cm2 V−1 s−1 were inferior to those of 1-based FETs with μFET s up to 3.0 cm2 V−1 s−1. The inferior characteristics of 2- and 3-based devices were due to film morphology as elucidated by atomic force microscopy (AFM) and supported by theoretical calculations of electronic structure in the solid state. Together, the results indicate that the molecular structure and shape, even for similar heteroarenes with the same molecular formula and symmetry, are important parameters to determine the solid-state properties of organic semiconductors.

著者

YUSUKE ISHIDA YOSHINOBU OKABE HIDENORI TOKUYASU RYOHEI KAJI GEN SUGIYAMA TOMOYUKI USHIJIMA YU SASAKI MAKIKO YASUMOTO KEI KURAOKA OSAMU TSURUTA MICHIO SATA

出版者

久留米大学医学部

雑誌

The Kurume Medical Journal (ISSN:00235679)

巻号頁・発行日

vol.60, no.2, pp.67-70, 2013-05-31 (Released:2014-04-14)

参考文献数

6

被引用文献数

3 10

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Ampullary tumors are diagnosed by endoscopic biopsy of the ampulla of Vater. We encountered a rare case of acute pancreatitis following endoscopic biopsy of the ampulla. A 53-year-old man referred to our hospital for detailed examination of a suspected tumor of the ampulla of Vater. We conducted endoscopic biopsy from the ampulla. He developed severe abdominal pain four hours after the procedure. The serum amylase and serum lipase were elevated and abdominal computed tomography (CT) revealed pancreatic enlargement and diffuse stranding of the peri-pancreatic fat, compatible with the findings of acute pancreatitis. We diagnosed the patient as having acute pancreatitis caused by endoscopic biopsy of the ampulla of Vater. Conservative therapy improved his condition, however, a large pancreatic walled-off necrosis (WON) developed. Therefore, we performed endoscopic ultrasonography (EUS)-guided cyst drainage on the 74th day after admission. The WON diminished gradually in size and the symptoms disappeared, and the patient was discharged in good physical condition on the 137th day after admission. In this case, the ampullary biopsy may have caused mucosal edema or intraductal hematoma, resulting in pancreatic duct obstruction. It is important for endoscopists both to be aware of this potential complication following endoscopic biopsy of the ampulla and to inform the patients about possible complications of this procedure.

著者

山口 恵三 渡辺 彰 鈴木 賢二 舘田 一博

出版者

公益財団法人 日本感染症医薬品協会

雑誌

The Japanese Journal of Antibiotics (ISSN:03682781)

巻号頁・発行日

vol.61, no.5, pp.289-302, 2008-10-25 (Released:2013-05-17)

著者

酒井 悠輔 坂本 信介 加藤 悟郎 岩本 直治郎 尾崎 良介 江藤 毅 篠原 明男 森田 哲夫 越本 知大

出版者

日本哺乳類学会

雑誌

哺乳類科学 (ISSN:0385437X)

巻号頁・発行日

vol.53, no.1, pp.57-65, 2013 (Released:2013-08-13)

参考文献数

22

被引用文献数

1

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飼育下でアカネズミ(Apodemus speciosus)の自然交配による繁殖を誘導できる飼育交配手法を検討した.巣穴環境を擬似的に再現することで繁殖が誘導できるとの作業仮説のもと,ケージ内の床敷きを覆うように板を設置した中蓋あり飼育ケージを考案した.季節的な環境要因の影響を考慮するため,自然環境温度・自然光周期条件である半野外飼育施設において中蓋あり条件と中蓋なし条件で交配実験を行った.さらに環境条件が一定の室内飼育施設においても中蓋あり条件で交配実験を行った.その結果,半野外飼育施設の中蓋なし条件で雌個体の妊娠が確認されたのは11個体中1個体で1例のみだったのに対し,同施設での中蓋あり条件では9個体中4個体で6例の繁殖が誘導された.さらに室内飼育施設での中蓋あり条件では10個体中4個体で12例の繁殖が誘導でき,繁殖したペアの多くが複数回の繁殖を行った.半野外飼育施設の結果から,飼育ケージに中蓋を設置し疑似巣穴環境を再現することで,飼育下においてアカネズミの繁殖が誘導できることが示唆された.さらに繁殖の誘導が困難とされてきた室内飼育条件においても,繁殖に適した物理環境条件下であれば中蓋を用いることで繁殖を誘導できることが明らかとなった.これらのことから,飼育下における本種の繁殖誘導には飼育ケージに中蓋を設置するという簡便な手法が有効であると考えられる.

著者

土井 隆義

出版者

日本社会学会

雑誌

社会学評論 (ISSN:00215414)

巻号頁・発行日

vol.58, no.4, pp.625-626, 2008-03-31 (Released:2010-04-01)

著者

原 浩貴 村上 直子 山下 裕司

出版者

日本口腔・咽頭科学会

雑誌

口腔・咽頭科 (ISSN:09175105)

巻号頁・発行日

vol.15, no.2, pp.245-252, 2003-02-28 (Released:2011-03-01)

参考文献数

14

被引用文献数

2

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2001年5月より2002年4月までの1年間に, いびき・OSAS患者32名に対し睡眠中のいびき音をMDに録音した後, マルチディメンジョナルボイスプログラムを用いて音響解析を行った.その結果, 周波数分析上, 単純いびき症例では, 基本周波数を中心とした一峰性のピークを持つものがほとんどであるのに対し, 閉塞性睡眠時無呼吸症候群例では, 1kHz以上の高周波数帯に複数のピークを持つ傾向がみとめられた.また雑音成分は, 単純いびき症でSPIが高く, 閉塞性睡眠時無呼吸症候群例でNHRが高い結果がえられた.

著者

田中 二良

出版者

公益社団法人 日本水産学会

雑誌

日本水産学会誌 (ISSN:00215392)

巻号頁・発行日

vol.24, no.8, pp.601-607, 1958 (Released:2008-02-29)

参考文献数

9

被引用文献数

7 10

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The common octopus, Octopus (Octopus) vulgaris LAMARCK, an important commercial species in Japan, are captured by means of the octopus pot, the hand line and the spear along the east coast of Boso Peninsula, Chiba Pref. (Fig. 1 and Table 1). The writer has made a biological study of the stock of this animal, using the statistic data of the octopus fisheries and based upon the number of specimens taken in Uchiura Bay near Kominato. The results obtained are summarized as follows; (1) It is believed that the octopus stock may be composed of two groups, one inhabiting the coast of Boso Peninsula throughout the year, the other migrating from the north to this district in winter (Figs. 2-5). (2) The maturation phase of the octopus is shown by the gonad index (R) as given in the following formula; R=G. W.×102/[B. W.-(G. W.+F. W.)], where G. W. denotes the gonad weight, F. W. the total weight of digestive organ contents, and B. W. denoting body weight. The relation between gonad index and maturity scale of the female octopus is shown in Table 2. (3) The breeding season is from March to November, and the biological minimum size is about 40cm in the male, 40-50cm in the female (Fig. 6). (4) The monthly increase in the rate of body weight deduced from the body composition (Fig. 7 and Table 3) and the length-weight relationship (Fig. 7 and Table 3) is 0.100 during from March to August, 0.180 from June to December. (5) It may be a reasonable assumption that the immigrant winter group breed during the first breeding season following the migration and that the newly hatched population will increase the available fishing stock from April to July of the following year. (6) Diminishing rate of the octopus stock is estimated by Dr. Tauti's method (1956) as 1-2% per day, 5-8% five days, 8-9% ten days and 13% per month (Table 4). Moreover, the diminishing rate per month is obtained by another Dr. Tauti's method ('53) as being 11%. (7) Judging from the diminishing rate caused by fishing, it may be said that the catch efficiency of the octopus pot is greater than that of the hand line.