著者

吉川 弘之

出版者

公益財団法人 日本学術協力財団

雑誌

学術の動向 (ISSN:13423363)

巻号頁・発行日

vol.12, no.11, pp.84-85, 2007-11-01 (Released:2012-02-15)

著者

苣木 浅彦 島 敞史 北風 嵐

出版者

Japan Association of Mineralogical Sciences

雑誌

岩石鉱物鉱床学会誌 (ISSN:00214825)

巻号頁・発行日

vol.73, no.3, pp.63-77, 1978-03-05 (Released:2008-08-07)

参考文献数

40

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To reconfirm whether minerals of luzonite-famatinite series form complete solid solution between them as Springer (1969) reported or limited solid solution having immiscibility gap from approximately 10 to 40 mol% Cu3SbS4 as Skinner (1960) inferred. 16 samples of luzonite and famatinite from 7 mines in Japan, Formosa and Philippines were examined by electron probe microanalyser (EPMA). The quantitative analytical data by EPMA for the samples are given in Tables 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12 and 13. The specimens from the Hokuetsu mine, Japan and the Mankayan mine, Philippines have most nearly stoichiometric composition of luzonite as from 0 to 3 mol% Cu3SbS4. They from the Lobo mine, Philippines and the Kinkaseki mine, Formosa have from 2 to 12 mol% Cu3SbS4, and from 2 to 7 or 36 to 41 mol% Cu3SbS4 in composition, respectively. Also luzonite-famatinite series minerals from the Teine, Kasuga and Akeshi mines, Japan have compositions of such wide range as from 19 to 71, 26 to 82 and 3 to 78 mol% Cu3SbS4, respectively. However, the composition corresponding to stoichiometric Cu3SbS4 of famatinite was not found during this study. Analytical data for 378 points in 16 specimens are summarized as shown in Fig. 5, and it is found that there is existance of minerals having continuous compositions between luzonite and famatinite except nearly famatinite end. Therefore it is concluded that the complete solid solution between them exists at low temperature as the result of Springer's examination.

著者

久留 景吾 恩田 裕一 河守 歩 加藤 弘亮

出版者

日本森林学会

雑誌

日本森林学会誌 (ISSN:13498509)

巻号頁・発行日

vol.95, no.5, pp.267-274, 2013-10-01 (Released:2013-11-13)

参考文献数

13

被引用文献数

9 23

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福島第一原子力発電所の事故により放射性物質が降下した福島県内の林相の異なる森林3地点を対象に, 樹冠から林床へ降下するリターを通じた放射性セシウムの移行の特徴を明らかにした。事故後4カ月目から11カ月間, 定期的にリターの134Csおよび137Csの放射能濃度を測定し, 降下量の解析を行った。リターの放射能濃度は総じて落葉広葉樹-アカマツ混交林よりもスギ人工林で高い値を示したのは, 事故発生時に広葉樹が落葉していたために, 飛散した放射性セシウムの多くが広葉樹の樹冠を通過して林床へ降下した結果と考えられる。一方, スギ人工林ではリターに伴う放射性セシウム降下量の累積値が大きく上昇し続けており, 調査終了時でも樹冠に放射性セシウムが相当量残存していることが確認された。2011年10月以降各林分でのリターの放射能濃度が概ね横ばいに推移する中, 放射性セシウム降下量は樹冠からのリター降下量に大きく影響されていることが明らかとなった。今後は降下するリターに加え, 樹冠における生葉の鉛直分布や林床でのリターの平面分布, 林内雨や樹幹流などを含めて総合的に放射性セシウムの移行機構を解明していく必要がある。

著者

加藤 博之 西原 学宣 大森 啓造 須永 俊明 徳永 蔵

出版者

日本救急医学会

雑誌

日本救急医学会雑誌 (ISSN:0915924X)

巻号頁・発行日

vol.4, no.1, pp.38-44, 1993-02-15 (Released:2009-03-27)

参考文献数

26

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A case of drug-induced fulminant hepatitis is reported. A 48-year-old female was transferred to Saga Medical School Hospital because of fever, general fatigue, jaundice and marked liver dysfunction after being treated by her private physician with several drugs containing antibiotics and aspirin DL-lysine. On admission, prothrombin time was prolonged (13%), but the patient's consciousness was clear. Viral markers for hepatitis A, B and C were negative. On the fourth hospital day, consciousness disturbance (hepatic coma: grade IV) developed, and despite intensive treatment including glucagon-insulin therapy and plasma exchange, the patients died of hepatic coma with multiple organ failure on the eleventh hospital day. The liver weighed 710g, and exhibited features of massive necrosis histologically. The lymphocyte stimulating test was positive for cefmetazol and aspirin DL-lysine. A review of literature showed that in Japan about 5% of cases of fulminant hepatitis are due to drugs other than halothane. In most cases reported recently, the lymphocyte stimulating test has been positive for the causative drugs.

著者

寺田 信人 上田 雅行 齊藤 寛

出版者

一般社団法人 スマートプロセス学会 (旧高温学会)

雑誌

スマートプロセス学会誌 (ISSN:2186702X)

巻号頁・発行日

vol.1, no.3, pp.133-137, 2012-05-20 (Released:2013-01-25)

参考文献数

15

被引用文献数

1

著者

Ozlem OZSOY-SACAN Omür KARABULUT-BULAN Sehnaz BOLKENT Refiye YANARDAG Yasemin OZGEY

出版者

(社)日本農芸化学会

雑誌

Bioscience, Biotechnology, and Biochemistry (ISSN:09168451)

巻号頁・発行日

vol.68, no.8, pp.1640-1648, 2004 (Released:2004-08-23)

参考文献数

51

被引用文献数

30

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Chard (Beta vulgaris L. var cicla) is one of the medicinal herbs used by diabetics in Turkey. It has been reported to reduce blood glucose. We have investigated the effect of chard extracts on the liver by biochemical and morphological investigation. The plant extract was administered by the gavage technique to rats at a dose of 2 g/kg every d for 28 d, 14 d after experimental animals were made diabetic. In the diabetic group, some degenerative changes were observed by light and electron microscope examination, but degenerative changes decreased or were not observed in the diabetic group given chard. In the diabetic group, blood glucose levels, serum alanine, aspartate transaminase, alkaline phosphatase activities, total lipids, sialic and uric acid levels, liver lipid peroxidation (LPO), and nonenzymatic glycosylation (NEG) levels increased, while blood glutathione, body weight, and liver glutathione (GSH) levels decreased. The diabetic group given chard, serum alanine, aspartate transaminase, alkaline phosphatase activities, total lipid level, sialic and uric acid levels, blood glucose levels, and liver LPO and NEG levels decreased, but the other values increased. As a result of all the morphological and biochemical findings obtained, it was concluded that the extract of this plant has a protective effect on the liver in diabetes mellitus.

著者

二瓶 俊一 岩本 謙荘 後藤 慶 原山 信也 毛利 文彦 相原 啓二 蒲地 正幸

出版者

公益社団法人 日本産業衛生学会

雑誌

産業衛生学雑誌 (ISSN:13410725)

巻号頁・発行日

vol.51, no.3, pp.35-40, 2008 (Released:2009-06-11)

参考文献数

20

被引用文献数

1

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産業保健と救急医療のかかわり:二瓶俊一ほか.産業医科大学病院救急・集中治療部―産業保健活動は,職場環境や作業方法により発生する健康障害のリスクを適切にコントロールすることが主要目的である.しかしリスクの低減によっても災害や病気を防げないことがある.事業所内で発生した災害や病気に対する初期対応は,産業保健スタッフにとって大変重要な仕事である.適切な初期対応により,災害や病気からの救命率を上げることも可能であり,発生した災害や病気に対するマネジメント=救急危機管理は,産業保健遂行上,大変重要である.従って,産業保健と救急医療の間には緊密な関係がある. (産衛誌2009; 51: 35-40)

著者

Jean-Claude LAUNAY Gustave SAVOUREY

出版者

独立行政法人 労働安全衛生総合研究所

雑誌

Industrial Health (ISSN:00198366)

巻号頁・発行日

vol.47, no.3, pp.221-227, 2009 (Released:2009-06-16)

参考文献数

79

被引用文献数

11 46

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Nowdays, occupational and recreational activities in cold environments are common. Exposure to cold induces thermoregulatory responses like changes of behaviour and physiological adjustments to maintain thermal balance either by increasing metabolic heat production by shivering and/or by decreasing heat losses consecutive to peripheral cutaneous vasoconstriction. Those physiological responses present a great variability among individuals and depend mainly on biometrical characteristics, age, and general cold adaptation. During severe cold exposure, medical disorders may occur such as accidental hypothermia and/or freezing or non-freezing cold injuries. General cold adaptations have been qualitatively classified by Hammel and quantitatively by Savourey. This last classification takes into account the quantitative changes of the main cold reactions: higher or lower metabolic heat production, higher or lesser heat losses and finally the level of the core temperature observed at the end of a standardized exposure to cold. General cold adaptations observed previously in natives could also be developed in laboratory conditions by continuous or intermittent cold exposures. Beside general cold adaptation, local cold adaptation exists and is characterized by a lesser decrease of skin temperature, a more pronounced cold induced vasodilation, less pain and a higher manual dexterity. Adaptations to cold may reduce the occurrence of accidents and improve human performance as surviving in the cold. The present review describes both general and local cold adaptations in humans and how they are of interest for cold workers.

著者

田淵 紀彦 村上 礼隆 福長 将仁

出版者

公益社団法人 日本薬学会

雑誌

YAKUGAKU ZASSHI (ISSN:00316903)

巻号頁・発行日

vol.133, no.12, pp.1417-1423, 2013 (Released:2013-12-01)

参考文献数

20

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Borrelia duttonii, a causative agent of relapsing fever, is transmitted between the distinct microenvironments of the vector tick, Ornithodoros moubata, and a mammalian host. We identified the total and membrane fraction proteins of B. duttonii strain Ly isolated from a patient in Tanzania by using two-dimensional gel electrophoresis with matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS). The analyses of the total and membrane fractions from bacterial cultures incubated at 37°C identified 68 and 15 proteins, respectively. Since spirochaete clearance in mice is associated with an immunoglobulin M (IgM) and immunoglobulin G3 (IgG3)-mediated response, immunoblot analyses were used to identify the proteins reactive with IgM and IgG3 of gerbil serum against B. duttonii strain Ly. The outcome showed that six proteins (antigen p83/100, membrane-associated protein P66 (P66), flagellar filament outer layer protein, hypothetical protein BDU_412, vlp protein gamma subfamily (γ-Vlp) and flagellin (FlaB)) were identified against IgM, and four (antigen p83/100, P66, γ-Vlp and FlaB) of the six proteins also reacted with IgG3. It is believed that these proteins are immunodominant antigens for the host immune response. Some of these immunogenic proteins might be used as molecular diagnostic tools in the study of relapsing fever in Tanzania.

著者

Hayato TAKEUCHI Kazuhide IWAMOTO Mao MUKAI Tomoaki FUJITA Hitoshi TSUJINO Yoshihiro IWAMOTO

出版者

社団法人 日本脳神経外科学会

雑誌

Neurologia medico-chirurgica (ISSN:04708105)

巻号頁・発行日

pp.cr2012-0376, (Released:2013-11-08)

参考文献数

27

被引用文献数

1 4

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Pathological laughing, one subgroup of psuedobulbar affect, is known as laughter inappropriate to the patient’s external circumstances and unrelated to the patient’s internal emotional state. The authors present the case of a 76-year-old woman with no significant medical history who experienced pathological laughing after subarachnoid hemorrhage (SAH) due to rupture of an aneurysm, which was successfully treated with craniotomy for aneurysm clipping. In the acute stage after the operation she suffered from severe vasospasm and resulting middle cerebral artery territory infarction and conscious disturbance. As she regained consciousness she was afflicted by pathological laughing 6 months after the onset of SAH. Her involuntary laughter was inappropriate to the situation and was incongruent with the emotional state, and she could not control by herself. Finally the diagnosis of pathological laughing was made and treatment with sertraline, a selective serotonin reuptake inhibitor (SSRI), effectively cured the symptoms. Her pathological laughing was estimated to be consequence of infarction in the right prefrontal cortex and/or corona radiata, resulting from vasospasm. To the authors’ knowledge, this is the first report of pathological laughing after aneurysmal SAH. The authors offer insight into the pathophysiology of this rare phenomenon. Effectiveness of sertraline would widen the treatment modality against pathological laughing.

著者

Shinji ARITA Noboru ARITA Yoshiaki HIKASA

出版者

公益社団法人 日本獣医学会

雑誌

Journal of Veterinary Medical Science (ISSN:09167250)

巻号頁・発行日

pp.13-0505, (Released:2013-12-06)

被引用文献数

1 3 1

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The purpose of this study was to determine the effect of pravastatin (PS) on hemodynamic parameters in healthy dogs. Five beagle dogs were repeatedly used in each of the 4 groups. One group was not medicated (control). Dogs in other groups received 0.5, 1.0 or 2.0 mg/kg PS orally q24hr, for 4 weeks. Physical examination, blood biochemical tests, blood pressure measurements and Doppler echocardiography were performed before and 1, 2 and 4 weeks after PS administration in all dogs. PS significantly reduced the left atrial-to-aortic diameter ratio (LA/Ao), early diastolic transmitral flow (E) wave, E/early diastolic mitral annulus motion velocity (Em) ratio, left ventricular (LV) fractional shortening, LV ejection fraction, mid systolic myocardial velocity gradient, stroke volume (SV), cardiac output (CO), right and left ventricular Tei indices and elevated Em and early diastolic myocardial velocity gradient. Heart rate was not significantly altered during PS administration, but mean blood pressure decreased slightly. The hematological and blood biochemical values were within normal limits during PS administration. These results revealed that PS administration increases LV expansion capacity and decreases LV constriction and left atrial pressure. It has been suggested that PS may be effective in improving heart failures with LV diastolic dysfunction or elevated left atrial pressure in dogs.

著者

Hang GUO Ai SAIGA Mikako SATO Izumi MIYAZAWA Makoto SHIBATA Yoshihisa TAKAHATA Fumiki MORIMATSU

出版者

Center for Academic Publications Japan

雑誌

Journal of Nutritional Science and Vitaminology (ISSN:03014800)

巻号頁・発行日

vol.53, no.4, pp.345-348, 2007 (Released:2007-10-05)

参考文献数

21

被引用文献数

20 68

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Royal jelly (RJ) has several physiological effects and is widely used in commercial medical products and health foods. We examined the effects of RJ supplementation on serum lipoprotein metabolism in humans. Fifteen volunteers were divided into an RJ intake group (n=7) and a control group (n=8). The RJ group took 6 g per day for 4 wk. Their serum total cholesterol (TC) and serum low-density lipoprotein (LDL) decreased significantly compared with those of the control group (p<0.05). There were no significant differences in serum high-density lipoprotein (HDL) or triglyceride concentrations. Moreover, the relationship between the serum cholesterol and lipoprotein levels was investigated. Among the lipoprotein fractions, small very-low-density lipoprotein was decreased (p<0.05) after RJ intake. Our results suggest that dietary RJ decreases TC and LDL by lowering small VLDL levels.

著者

Kui Xiao Jiehan Jiang Chaxiang Guan Chunling Dong Guifang Wang Li Bai Jiayuan Sun Chengping Hu Chunxue Bai

出版者

(公社)日本薬理学会

雑誌

Journal of Pharmacological Sciences (ISSN:13478613)

巻号頁・発行日

vol.123, no.2, pp.102-109, 2013-10-20 (Released:2013-10-19)

参考文献数

57

被引用文献数

21 88

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Curcumin is a major yellow pigment and active component of turmeric widely used as dietary spice and herbal medicine. This compound has been reported to be a promising antitumor agent, although the underlying molecular mechanisms are not fully understood yet. In this study, we reported that curcumin inhibited growth of lung adenocarcinoma cells, but had no cytotoxic activity to IMR-90 normal lung fibroblast cells. Curcumin induced autophagy in the A549 human lung adenocarcinoma cell line, evidenced by LC3 immunofluorescence analysis and immunoblotting assays on LC3 and SQSTM1. Moreover, the autophagy inhibitor 3-MA partly blocked the inhibitory effect of curcumin on the growth of A549 cells. Curcumin markedly increased the phosphorylation of AMP-activated protein kinase (AMPK) and acetylCoA carboxylase in A549 cells. At last, pharmacological blockade of the AMPK signaling pathway by compound C and genetic disruption of the AMPK signaling pathway with siRNA-mediated AMPKα1 knockdown impaired the autophagy-inducing effect of curcumin. Collectively, our data suggests that curcumin induces autophagy via activating the AMPK signaling pathway and the autophagy is important for the inhibiting effect of curcumin in lung adenocarcinoma cells.

著者

花井 孝明 桑原 裕史 近藤 邦和 箕浦 弘人 伊藤 明 近藤 一之 江崎 尚和 川口 雅司 井上 哲雄 Michael E. Lawson

出版者

公益社団法人 日本工学教育協会

雑誌

工学教育 (ISSN:13412167)

巻号頁・発行日

vol.56, no.3, pp.3_68-3_73, 2008 (Released:2008-06-14)

参考文献数

3

被引用文献数

1 1

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One of the educational goals of the Advanced Engineering Faculty of Suzuka National College of Technology is to instill in graduates the ability required to become an internationally engaged engineers. To help realize this goal a project oriented toward the development of an international internship or an international cooperative education (Co-op) system was planned and implemented for the past three years. In this paper the results of investigations concerning the present state of Co-op in the United States and Canada, a tentative international internship at a factory in the United States, and an educational program developed in cooperation with Georgian College in Canada are described. In cooperation with the Ohio State University, a newly developed distance interactive-learning system that enables us to simulate international internships is also proposed.

著者

Akira Kawaguchi

出版者

日本微生物生態学会 / 日本土壌微生物学会 / Taiwan Society of Microbial Ecology / 植物微生物研究会

雑誌

Microbes and Environments (ISSN:13426311)

巻号頁・発行日

vol.28, no.3, pp.306-311, 2013 (Released:2013-09-21)

参考文献数

27

被引用文献数

7 29

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A nonpathogenic strain of Rhizobium vitis ARK-1 was tested as a biological control agent for grapevine crown gall. When grapevine roots were soaked in a cell suspension of strain ARK-1 before planting in the field, the number of plants with tumors was reduced. The results from seven field trials from 2009 to 2012 were combined in a meta-analysis. The integrated relative risk after treatment with ARK-1 was 0.15 (95% confidence interval: 0.07–0.29, P<0.001), indicating that the disease incidence was significantly reduced by ARK-1. In addition, the results from four field trials from 2007 to 2009 using R. vitis VAR03-1, a previously reported biological control agent for grapevine crown gall, were combined in a meta-analysis. The integrated relative risk after treatment with VAR03-1 was 0.24 (95% confidence interval: 0.11–0.53, P<0.001), indicating the superiority of ARK-1 in inhibiting grapevine crown gall over VAR03-1 under field conditions. ARK-1 did not cause necrosis on grapevine shoot explants. ARK-1 established populations on roots of grapevine tree rootstock and persisted inside roots for two years.

著者

前岡 浩 福本 貴彦 坂口 顕 長谷川 正哉 金井 秀作 高取 克彦 冷水 誠 庄本 康治

出版者

理学療法科学学会

雑誌

理学療法科学 (ISSN:13411667)

巻号頁・発行日

vol.23, no.4, pp.529-533, 2008 (Released:2008-10-09)

参考文献数

16

被引用文献数

11 4

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[目的]フリーウェアであるImageJは顕微鏡画像の処理,解析に利用されているが,角度測定機能は理学療法分野でも活用可能と考えた。そこで,立ち上がり動作を利用し,ImageJによる体幹前傾角度測定の信頼性を検証した。[対象]被験者は3名,ImageJを使用する検者を10名とした。[方法]被験者に左側の肩峰,大転子,膝関節外側関節裂隙に反射マーカーを貼付し,立ち上がり動作を矢状面から1回撮影した。体幹前傾角度はImageJおよび三次元動作解析装置で測定した。[結果]級内相関係数と標準誤差を用いて統計解析を行った結果,検者内・検者間信頼性を示すICCはともに高かった。[結語]ImageJを用いた二次元での動作分析は理学療法分野における評価や研究,教育に有益な手段である可能性が示唆された。

著者

Tadahiko Ito Arata Watanabe Jinzo Akabane

出版者

東北ジャーナル刊行会

雑誌

The Tohoku Journal of Experimental Medicine (ISSN:00408727)

巻号頁・発行日

vol.192, no.2, pp.151-155, 2000 (Released:2005-04-15)

参考文献数

9

被引用文献数

5 11

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A child with acute disseminated encephalomyelitis (ADEM) developed after acute herpetic gingivostomatisis was described. Inspite of the improvement of his gingivostomatitis, his consciousness gradually deteriorated and he was admitted to Nakadori General Hospital. His consciousness level was drowsiness and increased bilateral patellar reflexes were shown. Because magnetic resonance imaging (MRI) T2-weighted scan showed areas of high signal intensity disseminated in superior portion of medulla oblongata, dorsal portion of pons, basal nuclei and thalamus, he was suspected as having ADEM. Anti-herpes simplex virus (HSV) 1 IgG and IgM antibodies elevated in both blood and cerebrospinal fluid. From these results, HSV1 infection was thought to be the preceding infection of ADEM. Methylprednisolone therapy (20 mg/kg daily) for 3 days, followed by prednisolone (2 mg/kg) was started, with an excellent response. In addition, administration of acyclovir was also continued, considering the complication of HSV encephalitis. MRI T2-weighted scan performed at 2 months later after the onset of ADEM revealed disappearance of the lesions. He was discharged without remaining disorders. It is difficult to distinguish between ADEM and HSV encephalitis because both of these diseases show various neurological symptoms. In our case, MRI was the most useful method for correct diagnosis of ADEM. We concluded that ADEM is important as a disease of central nervus system due to HSV1 infection, in addition to encephalitis.

著者

横川 京児 河村 正敏 新井 一成 塩川 章 太田 秀一

出版者

昭和大学学士会

雑誌

昭和医学会雑誌 (ISSN:00374342)

巻号頁・発行日

vol.51, no.4, pp.419-428, 1991-08-28 (Released:2010-09-09)

参考文献数

28

被引用文献数

1

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大腸癌の予後を左右する重要な因子に血行性転移があげられる.特に肝転移は予後に大きく関与しており, 静脈侵襲の程度を観察することにより, 肝転移の危険性を予測することが十分可能であると考えられる.今回著者らは, 進行大腸癌治癒切除症例における静脈侵襲状況をVictria blue-H・E染色を用い観察し, 静脈侵襲の有無, 侵襲程度, 侵襲部位および侵襲静脈径を検索し, これらの肝転移への関与, ならびにその臨床病理学的意義を検討した.対象は, 教室における過去8年間 (1981.1~1988.12) の初発大腸進行癌切除症例378例中単発大腸癌治癒切除症例220例である.静脈侵襲陽性は141例 (64.1%) であり, これらの静脈侵襲頻度をv1; 1~2個, v2; 3~6個, v3; 7個以上, に分け, また, 侵襲静脈径を各症例の最も太い静脈径によりS・M・L群に分類し検討した.侵襲頻度別にみるとv1: 80例 (56.7%) , v2: 48例 (34.0%) , v3: 13例 (9.3%) , 侵襲径ではS群: 18例 (12.8%) , M群: 95例 (67.4%) , L群: 28例 (19.9%) であり, 両者の問に相関関係がみられ, 侵襲頻度が多いものほど, 侵襲径の大きい群に属した.v (+) 例では中分化癌, a2+Sが有意に高率であった.静脈侵襲頻度, 侵襲静脈径と占居部位, 組織型, 深達度およびリンパ節転移との問に相関をみられなかったが, リンパ管侵襲のうち1y3とに相関関係を認めた.予後の検討では, v (-) , v (+) 症例の5生率はそれぞれ84.2%, 58.6%と有意差がみられ, 静脈侵襲頻度が高い症例ほど, また静脈侵襲径が太いほど予後不良であった.肝再発は17例 (7.7%) にみられ, うち16例がv (+) であった.静脈侵襲頻度別にみると, v0: 1.2%, v1: 5.0%, v2: 12.5%, v3: 46.2%, 侵襲静脈径別では, S群: 5.6%, M群: 7.4%, L群: 28.6%, また, 漿膜下層静脈侵襲の有無で比較すると, ssv (+) : 16.3%, ssv (-) : 3.6%であり, 静脈侵襲頻度の高いもの, 侵襲静脈径の太いもの, ssv (+) で有意に肝再発がみられた (p<0.05) .また, 占居部位, 組織型, リンパ管侵襲およびリンパ節転移では相関関係がみられず, 深達度のみに肝再発との相関関係を認めた.以上, 大腸癌における静脈侵襲状況は術後肝再発を予測するうえできわめて重要であり, これらの危険因子の大きい症例では治癒切除症例であっても厳重な経過観察が必要であると考えられた.

著者

Ryoko Kawakami Susumu S. Sawada Munehiro Matsushita Takashi Okamoto Koji Tsukamoto Mitsuru Higuchi Motohiko Miyachi

出版者

日本疫学会

雑誌

Journal of Epidemiology (ISSN:09175040)

巻号頁・発行日

pp.JE20130076, (Released:2013-11-16)

参考文献数

23

被引用文献数

3 12

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Background: In “Physical Activity Reference for Health Promotion 2013” the Japan Ministry of Health, Labour and Welfare publication gives reference values for cardiorespiratory fitness (CRF) required for good health. We examined the associations between the CRF reference values and incidence of type 2 diabetes.Methods: This prospective cohort study enrolled 4633 nondiabetic Japanese men aged 20 to 39 years at baseline. CRF was measured using the cycle ergometer test, and maximal oxygen uptake was estimated. On the basis of the CRF reference value, participants were classified into 2 groups: those with values less than the reference value (under-RV) and those with values equal to or greater than reference value (over-RV). Hazard ratios (HRs) and 95% CIs for incident type 2 diabetes were estimated using a Cox proportional hazards model.Results: A total of 266 participants developed type 2 diabetes during the 14 years of follow-up. As compared with the under-RV group, the over-RV group had a significantly lower multivariable-adjusted HR for type 2 diabetes (HR 0.67; 95% CI, 0.51–0.89). In receiver operating characteristic analysis, the optimal CRF cut-off value for predicting incident type 2 diabetes was 10.8 metabolic equivalents (sensitivity, 0.64; specificity, 0.64), which was close to the CRF reference value of 11.0 metabolic equivalents.Conclusions: The reference CRF value appears to be reasonably valid for prevention of type 2 diabetes, especially among Japanese men younger than 40 years. Development of type 2 diabetes can be prevented by maintaining a CRF level above the reference value.

著者

亀井 卓也 伊藤 那知 菅井 慎也 太田 諭志 佐鳥 新 千葉 一永

出版者

一般社団法人 日本航空宇宙学会

雑誌

航空宇宙技術 (ISSN:18840477)

巻号頁・発行日

vol.12, pp.111-117, 2013 (Released:2013-11-28)

参考文献数

16

被引用文献数

1 1

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Precision agriculture has been being implemented in order environmentally friendly and efficiently to product and manage crops. The remote sensing by satellite and aircraft is employed in order to obtain the information regarding the growth of crops. Although the data from satellites can include wide-range image each time, it is insufficient due to the fixed orbital path of satellites. Therefore, fixed-point observations cannot be sufficiently performed. Moreover, the observations on fixed orbital path cannot be always carried out because of cloud. Although aircrafts are used for the interpolation of the insufficient data by satellites, manned aircrafts need high personnel expenses and maintenance costs. Therefore, unmanned aerial vehicle (UAV) is recently employed. The objective of the present study is the development of the system to generate the interpolated image data by normalized difference vegetation index (NDVI) map taken by small-type UAV (sUAV), which is low-priced and simple system to implement precision agriculture. The following three assignments have been concretely performed in the present study; 1) light-weight four-band multispectral camera carried in sUAV will be developed, 2) sUAV is managed and the image data will be taken, and 3) NDVI map will be generated from the image data by sUAV and interpolated image data will also be developed to contribute precision agriculture. Consequently, the lightest four-band multispectral camera in the world has been developed, and also sUAV has been able to be successfully managed and acquired image data could also generates NDVI maps.