著者

Yasunori NISHIKAWA Sogo SAYAMA Yoshinobu UEDA Yoshikazu SUZUKI

出版者

The Iron and Steel Institute of Japan

雑誌

Transactions of the Iron and Steel Institute of Japan (ISSN:00211583)

巻号頁・発行日

vol.23, no.8, pp.639-645, 1983 (Released:2006-09-08)

参考文献数

13

被引用文献数

1 1

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The effect of K2O, Na2O and CaO on the reduction behavior of Fe2O3 was investigated. Platelets of Fe2O3 single crystals were prepared by the flux method. The size of the crystals was approx. 3mm in width and 0.3mm in thickness. For the reaction of Fe2O3 with K2O, Na2O, and CaO, small amounts of each carbonate powder were placed on the flat plane (0001) of Fe2O3 and heated at 1100-1300°C in the air. It was confirmed by EPMA that the reaction products with those substances were formed on some parts of the Fe2O3 crystal. The crystals were reduced at 750°C in CO and H2 streams, and the surface structures were observed by SEM.The results obtained were as follows. When alkaline metals (as Na2O, K2O) were present in Fe2O3, the abnormal swelling took place during the reduction. It was considered that the swelling was caused by (1) the cracking of the crystal at the early stage of the reduction, (2) the fibrous iron formation and (3) the carbon deposition on the reduced iron. The fibrous iron formation was also observed in the grain boundary of calcium ferrite. The reduction with a glassy slag (SiO2-Al2O2-CaO) was also investigated and no swelling phenomenon was shown.

著者

Tomohiro Koga Kanako Takano Yoshiro Horai Satoshi Yamasaki Hideki Nakamura Akinari Mizokami Koichi Ohshima Atsushi Kawakami

出版者

一般社団法人 日本内科学会

雑誌

Internal Medicine (ISSN:09182918)

巻号頁・発行日

vol.52, no.16, pp.1839-1843, 2013 (Released:2013-08-15)

参考文献数

15

被引用文献数

3

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A 21-year-old man was admitted to our hospital with a fever, erythema, cervical lymphadenopathy and pancytopenia. A diagnosis of Sweet's syndrome (SS) with Kikuchi's disease (KD) and hemophagocytic syndrome (HPS) was made based on the results of a bone marrow aspiration along with the results from biopsy specimens of the brachial skin and a cervical lymph node. The expression of retinoic acid-inducible gene-I (RIG-I) in the skin epidermal basal layer as well as in a cervical lymph node was revealed through immunohistochemistry. He successfully entered remission through treatment with prednisolone. This findings of this case indicate that when SS with KD presents as HPS, it may suggest an association with an RIG-I-related innate immunity.

著者

武田 多一

出版者

公益社団法人 日本薬学会

雑誌

YAKUGAKU ZASSHI (ISSN:00316903)

巻号頁・発行日

vol.130, no.4, pp.589-591, 2010 (Released:2010-04-01)

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Emergency medicine is an interdisciplinary area that covers medical care in an emergency room, trauma center and intensive care unit. It also provides prehospital emergency medical service and disaster medicine. Pharmacists are expected to play major roles as a member of the emergency medical team. The roles of pharmacist include inventory management, formulary management, administration guidance, medication delivery, identification of a tablet, analysis of intoxicating substance, and therapeutic drug monitoring. During disaster response, accompanying disaster relief team to provide supervision for stock and prescription of medications could also be an important mission of a pharmacist. As a member of the emergency medical team, knowledge and skills for effective communication is essential to discuss patients' condition and therapeutic strategy with other healthcare providers. Basic life support and first-aid ability are mandatory to all the medical professionals who take care of patients. Safety and security management at the emergency or disaster scene is another important requirement. We hope more pharmacists will join the emergency and disaster medicine and contribute to extend a hand to the sufferers.

著者

柴藤 羊二 秋元 敏男

出版者

一般社団法人 日本航空宇宙学会

雑誌

日本航空宇宙学会誌 (ISSN:00214663)

巻号頁・発行日

vol.26, no.298, pp.607-610, 1978-11-05 (Released:2009-07-09)

著者

中野 孝教

出版者

公益社団法人 日本アイソトープ協会

雑誌

RADIOISOTOPES (ISSN:00338303)

巻号頁・発行日

vol.42, no.6, pp.381-382, 1993-06-15 (Released:2010-07-21)

参考文献数

10

著者

Wei ZHANG Chunyan WANG Deqing CHEN Masako MINAMIHISAMATSU Hiroshige MORISHIMA Yongling YUAN Luxin WEI Tsutomu SUGAHARA Isamu HAYATA

出版者

Journal of Radiation Research 編集委員会

雑誌

Journal of Radiation Research (ISSN:04493060)

巻号頁・発行日

vol.45, no.3, pp.441-446, 2004 (Released:2004-12-22)

参考文献数

26

被引用文献数

16

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Cytogenetic investigation of stable-type aberrations (translocations) was carried out with our improved methods on 28 elderly individuals in a high-background radiation area (HBRA) in China, and on 24 elderly individuals in a control area (CA). The level of radiation in HBRA is 3 to 5 times higher than in CA. The mean frequencies of translocations per 1,000 cells in HBRA and CA were 12.4 ± 5.3 and 10.0 ± 3.8, respectively. No significant difference was found in the frequencies between HBRA and CA (P>0.05, Mann-Whitney U test). When elderly individuals in HBRA and CA were classified into four subgroups of HBRA nonsmokers, HBRA smokers, CA nonsmokers, and CA smokers, a significant difference was found in the frequencies between CA smokers and CA nonsmokers (P<0.05, Mann-Whitney U test). Furthermore a tendency of difference (a near T-value of 0.05 level) was found in a comparison of HBRA smokers vs. CA nonsmokers. The present results indicate that the elevated level of natural radiation in HBRA plays a less significant part than smoking in bringing about the induction rate of stable-type aberrations (translocations) in those areas.

著者

三吉 建尊 越野 亮 笠原 竹博 上田 芳弘 木村 春彦

出版者

日本知能情報ファジィ学会

雑誌

知能と情報 (ISSN:13477986)

巻号頁・発行日

vol.24, no.4, pp.909-919, 2012-08-15 (Released:2012-09-05)

参考文献数

15

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現在,工作機械用の制御盤内において,部品同士をハーネスと呼ばれる電線で結線する作業は手作業で行われており,自動化が求められている.本研究では機械によるハーネス結線作業の自動化を行うために,部品に予め取り付けられているハーネス取り付け用のネジ位置を検出すること.そして機械によってハーネスが取り付けられた後に,正しくハーネスが取り付けられているか検査を行うこと.これら2つの処理を画像認識によって行う.本研究では,機械学習によって画像の特徴量を学習して識別するという,一般物体認識の手法を用いる.特徴量の計算には HOG と Bag of Keypoints を用いる.そして得られた特徴量を機械学習によって学習・識別を行うことによって画像認識を行う.本稿では,上記の手法を用いたネジとハーネスの認識率について報告する.

著者

門田 明

出版者

日本英学史学会

雑誌

英学史研究 (ISSN:03869490)

巻号頁・発行日

vol.1978, no.10, pp.91-100, 1977-09-01 (Released:2009-09-16)

参考文献数

8

著者

平田 宗史

出版者

一般社団法人 日本教育学会

雑誌

教育学研究 (ISSN:03873161)

巻号頁・発行日

vol.45, no.1, pp.1-12, 1978-03-30 (Released:2009-01-13)

参考文献数

71

著者

根本 正之 長崎 祐二 池田 正治

出版者

日本雑草学会

雑誌

雑草研究 (ISSN:0372798X)

巻号頁・発行日

vol.37, no.2, pp.159-166, 1992-07-31 (Released:2009-12-17)

参考文献数

13

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近年, 沖繩本島や八重山群島においてオガサワラスズメノヒエが優占する荒廃草地が増加してきた。オガサワラスズメノヒエは, 周年に亘って成長する, 生育型が叢生-ほふく型のイネ科多年生雑草で, 家畜に対しても有害である。したがってその防除法の確立が望まれるが, オガサワラスズメノヒエの生理・生態や防除に関する研究は殆どないので, オガサワラスズメノヒエが発生したいくつかの人工草地で生態学的調査を行った。オガサワラスズメノヒエは草地内で純群落を形成するまでには至らないが, 採草地周辺部あるいは刈り取り作業機の横すべりや, 牧草の取り残し等によって生じた裸地にいったん侵入すると, その形態的可塑性を有効に発揮し, 確実に空間を占有した。一度草地内に侵入したオガサワラスズメノヒエの防除は極めてむずかしいが, オガサワラスズメノヒエより草丈が高く, かつ, ほふく型で地表面を被覆する性質をそなえたジャイヤントスターグラスの牧草としての導入はオガサワラスズメノヒエ群落の抑制に有効であるらしいことがわかった。

著者

酒井 博 佐藤 徳雄 奥田 重俊 秋山 侃

出版者

日本雑草学会

雑誌

雑草研究 (ISSN:0372798X)

巻号頁・発行日

vol.21, no.3, pp.101-107, 1976-10-25 (Released:2009-12-17)

参考文献数

11

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沖繩における放牧用人工草地の雑草調査を行ない, 雑草の種類, 群落区分, その動態について, 次のような結果をえた。1) 雑草の種類は主に熱帯, 亜熱帯に分布するものが多く, 温帯に属する内地の種類と異なるが, 草種全体の生活型組成では大きな差異は認められない。2) 沖繩本島安田の草地は, スダジイ林を伐採して造成したもので, キク科の一年生雑草が多い。立地条件や放牧強度の差異によりワタナ-チチコグサ群落, バヒアグラス群落, ツルメヒシバ群落, イヌタデ群落, コバナビメハギ-ヒメジソ群落, リュウキュウイチゴ群落が成立し, 群落間に遷移がみられる。3) 石垣島, 与那国島では, 半自然草地を含んで群落を区分した。海岸風衝地域では半自然草地のコウライシバ-ソナレムグラ群集がみられる。隆起珊瑚礁を母材とする石灰質土壌上の草地はチガヤ草原から造成されたものが多く, チガヤ-スズメノコビエ群集が広くみられる。第3紀層砂岩に由来する酸性土壌上では, 前歴が耕作地の草地にノジアオイ-オガサワラスズメノヒエ群落が, 前歴がススキ草原の草地にカラスキバサンキライ-ススキ群落がみられる。4) 種の結びつきをもとに, 前記の群落間の類似関係を明らかにし, 人工草地における土壌条件や家畜の放牧圧などに対応した雑草群落の動態について考察を行なった。

著者

Etsuji Okamoto Kiyotaka Kikuchi Ginji Endo

出版者

(公社)日本産業衛生学会

雑誌

Journal of Occupational Health (ISSN:13419145)

巻号頁・発行日

pp.13-0067-BR, (Released:2013-09-10)

被引用文献数

2 7

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Objectives: The aim of this study was to assess the risk of developing bile duct cancer among workers in the printing industry in comparison with workers in all industries in general. Methods: Prevalence of bile duct cancer was compared between workers in the printing industry and age-standardized controls in all other industries using the claims database of the Japan Health Insurance Association, which insures workers of small-medium sized employers of all industries. Results: Young (aged 30-49) male workers in the printing industry showed an elevated but insignificant standardized prevalence rate ratio (SPRR) for bile duct cancer in comparison with workers in all other industries (SPRR, 1.78; 95%CI,0.63-5.00). The risk was higher for intrahepatic bile duct cancer but remained insignificant (SPRR,3.03; 95%CI,0.52-17.56). Conclusions: The sharply elevated risk of bile duct cancer observed among proof-printing workers of a printing factory in Osaka may not be generalizable to workers in the printing industry nationwide.

著者

橋本 かほる 能登谷 晶子 原田 浩美 伊藤 真人 吉崎 智一

出版者

日本聴覚医学会

雑誌

AUDIOLOGY JAPAN (ISSN:03038106)

巻号頁・発行日

vol.55, no.2, pp.132-137, 2012 (Released:2012-06-15)

参考文献数

10

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幼児期金沢方式による言語訓練中に人工内耳を装用した12例の就学後の問題点と対策について報告した。就学時までに3000語以上の文字言語理解を獲得した文字先行移行パターンを示した8例中7例は就学以降も学業に著しい問題を示さず, 人工内耳においても文字言語の有用性が示唆された。幼児期に手話先行未移行パターン, 文字先行未移行パターンを示した例は就学以降の言語習得に問題が多いことがわかった。したがって, 人工内耳装用後も就学前に十分な言語力を獲得しておく必要があると考えた。さらに, 就学以降も言語力ならびに構音の維持のために定期的な評価・指導の必要性が示唆された。

著者

齋藤 秀哉 南 勝

出版者

公益社団法人 日本薬理学会

雑誌

日本薬理学雑誌 (ISSN:00155691)

巻号頁・発行日

vol.110, no.3, pp.97-99, 1997 (Released:2007-01-30)

著者

今枝 法之

出版者

日本社会学会

雑誌

社会学評論 (ISSN:00215414)

巻号頁・発行日

vol.35, no.3, pp.319-332,383, 1984-12-31 (Released:2009-11-11)

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Both 'the postulate of adequacy' (A. Schutz) and 'double hermeneutic' (A. Giddens) can be considered as critiques of positivism. I think positivism has two main components, the 'unity of science' and the 'rationality of science'. The 'rationality of science' is my coinage. It refers to the belief that scientific knowledge is rational and objective and much better than any other forms of knowledge epistimologically.Traditionally some social theorists have critisized solely the idea of the “unity of science”. That has depended on the dichotomy of 'Geisteswissenschaften' and 'Naturwissenschaften'. Schutz and Giddens refute the “unity of science”, too. Their views can be seen as up-to-date styles of criticism on positivism. But I argue that their critiques do not necessarily succeed. So I will suggest that to gain the post-positivistic self-understanding of sociology, sociologists must criticize not only the 'unity of science' but also the 'rationality of science' by reference to Feuerabend.

著者

池本 敦

出版者

日本脂質栄養学会

雑誌

脂質栄養学 (ISSN:13434594)

巻号頁・発行日

vol.21, no.1, pp.17-25, 2012 (Released:2012-04-29)

参考文献数

26

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Rats fed n-3 fatty acid deficient diet through two generations exhibit decreased correct response ratios in a brightness-discrimination learning test. This is associated with a decreased docosahexaenoic acid (DHA) to arachidonic acid (AA) ratio in brain lipids. The altered learning behavior associated with a long-term n-3 deficiency was reversed by supplementing DHA after weaning only when the levels of competing n-6 fatty acids in the diet and brain lipids are limited. Endocannabinoid 2-arachidonoylglycerol (2-AG) levels were significantly elevated in the brain of n-3 deficient rats. We evaluated the effect of cannabinoid receptor CB1 antagonist SR141716A (SR) on the learning behavior. SR did not ameliorate the decreased learning performance in the n-3 deficient rats. However, the increased locomotor activity by n-3 deficiency was suppressed by SR. Therefore, the altered behavior is associated with, at least in part, the endocannabinoid signaling. We also found the decreased nerve growth factor (NGF) content and the increased level of the activated form of calmodulin kinase II in the hippocampus of n-3 deficient rats. DHA has an essential role in biomembrane structure and functions, which affect the cellular signaling related to learning behavior.

著者

Masashi WATANABE Kazuaki TANAKA Tatsuya TAKIZAWA Kazuhito SEGAWA Sakurako NEO Ryo TSUCHIYA Michiko MURATA Masaru MURAKAMI Masaharu HISASUE

出版者

公益社団法人 日本獣医学会

雑誌

Journal of Veterinary Medical Science (ISSN:09167250)

巻号頁・発行日

pp.13-0316, (Released:2013-09-13)

被引用文献数

1 2

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A polymorphic tetranucleotide (GAAT)n microsatellite in the first intron of the canine tumor necrosis factor alpha (TNFA) gene was characterized in this study; 139 dogs were analyzed: 22 Beagles, 26 Chihuahuas, 20 Miniature Dachshunds, 24 Miniature Poodles, 22 Pembroke Welsh Corgis and 25 Shiba Inus. We detected the presence of the 4 alleles (GAAT)5, (GAAT)6, (GAAT)7 and (GAAT)8, including 9 of the 10 expected genotypes. The expected heterozygosity (He) and the polymorphic information content (PIC) value of this microsatellite locus varied from 0.389 to 0.749 and from 0.333 to 0.682, respectively, among the 6 breeds. The allelic frequency differed greatly among breeds, but this microsatellite marker was highly polymorphic and could be a useful marker for the canine TNFA gene.

著者

Manabu KOIKE Yasutomo YUTOKU Aki KOIKE

出版者

公益社団法人 日本獣医学会

雑誌

Journal of Veterinary Medical Science (ISSN:09167250)

巻号頁・発行日

pp.13-0283, (Released:2013-09-10)

被引用文献数

4

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Various chemotherapeutic drugs, such as etoposide, and ionizing radiation (IR) have been clinically applied for the treatment of many types of animal and human malignancies. IR and chemotheraputic drugs kill tumor cells mainly by inducing DNA double-strand breaks (DSBs). On the other hand, unrepaired or incorrectly repaired DSBs can lead to chromosomal truncations and translocations, which can contribute to the development of cancer in humans and animals. Thus, it is important to clarify the molecular mechanisms underlying the chemosensitivity or radiosensitivity of mammalian cells in order to develop medical treatments and next-generation chemotherapeutic drugs for cancer. Previously, we established and analyzed cell lines stably expressing chimeric constructs of EGFP and the wild-type Ku80 (XRCC5) protein or its mutant protein to which mutations were introduced by the site-directed mutagenesis. We found that the Ku70 (XRCC6)-binding-site mutations (A453H/V454H) of Ku80 and nuclear localization signal (NLS)-dysfunctional mutations (K565A/K566A/K568A) affected the ability to complement etoposide sensitivity. In this study, we examined the radiosensitivity of these cell lines. We found that either or both amino acid substitutions in two functional domains of Ku80, i.e., Ku70-binding-site mutations (A453H/V454H) and NLS-dysfunctional mutations (K565A/K566A/K568A), affect the ability to complement radiosensitivity. Moreover, these mutations in the two domains of Ku80 affect the DSB-sensing ability of Ku80. These information and Ku80 mutant cell lines used might be useful for the study of not only the dynamics and function of Ku80, but also the molecular mechanism underlying the cellular response to IR and chemotherapeutic drugs in mammalian cells.

著者

Kyoko Hayashi Kazuto Narutaki Yasuo Nagaoka Toshimitsu Hayashi Shinichi Uesato

出版者

公益社団法人日本薬学会

雑誌

Biological and Pharmaceutical Bulletin (ISSN:09186158)

巻号頁・発行日

vol.33, no.7, pp.1199-1205, 2010-07-01 (Released:2010-07-01)

参考文献数

23

被引用文献数

33 123

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Arctiin and its aglucone, arctigenin from the fruits of Arctium lappa L. showed potent in vitro antiviral activities against influenza A virus (A/NWS/33, H1N1) (IFV). Based on the data from time-of-addition experiments and on release tests of progeny viruses, arctigenin was assumed to interfere with early event(s) of viral replication after viral penetration into cells, and to suppress the release of progeny viruses from the host cells. Arctiin was orally effective against either IFV-inoculated normal or 5-fluorouracil (5-FU)-treated mice, being less effective as compared with oseltamivir. Noticeably, arctiin produced a larger amount of virus-specific antibody than those of control and oseltamivir in sera collected from 5-FU-treated mice. Furthermore, oral treatment of 5-FU-treated mice with arctiin did not induce any resistant viruses, although the same treatment with oseltamivir induced resistant viruses at a 50% frequency. When the combination of arctiin and oseltamivir was administered to normal mice infected with IFV, the virus yields in both bronchoalveolar lavage fluids and lungs were significantly reduced relative to those in the mice treated with arctiin or oseltamivir alone. Thus, monotherapy of arctiin or combined therapy of arctiin with oseltamivir would be another treatment option for influenza.

著者

江崎 春雄 屋代 幹雄 福島 修

出版者

農業食料工学会

雑誌

農業機械学会誌 (ISSN:02852543)

巻号頁・発行日

vol.49, no.1-2, pp.117-125, 1987 (Released:2010-04-30)

参考文献数

8

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ラッカセイの莢実の圧縮・せん断・衝撃等の外力に対する抵抗力ならびに莢リングの引張抵抗力を測定すると共に, これらの抵抗力と莢の組織構造との関連について若干の考察を行い, 落花生割莢機設計のための基礎資料の一部を提供した。