著者

高埜 利彦 Toshihiko Takano

出版者

学習院大学史学会

雑誌

学習院史学 = Gakushuin historical review (ISSN:02861658)

巻号頁・発行日

no.42, pp.5-7, 2004-03-20

著者

竹内 望 伊藤 直人

出版者

公益社団法人 日本雪氷学会/日本雪工学会

雑誌

雪氷研究大会講演要旨集 雪氷研究大会(2012・福山) (ISSN:18830870)

巻号頁・発行日

pp.84, 2012 (Released:2012-10-24)

著者

林 誠 杉村 勇人 菅 幸生 河原 昌美 相宮 光二 宮本 謙一

出版者

一般社団法人日本医療薬学会

雑誌

医療薬学 (ISSN:1346342X)

巻号頁・発行日

vol.35, no.2, pp.89-95, 2009 (Released:2010-02-07)

参考文献数

22

被引用文献数

10 13

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Hiccups often occur in patients receiving cisplatin (CDDP)-based chemotherapy.In the present study,we investigated the incidence of hiccups in 162 patients who received CDDP as well as risk factors for developing hiccups.Hiccups occurred in 40 (25%) of the 162 patients,and 93% were men.Twenty-six of the patients had hiccups within 48 hr of CDDP,and in 31 of them the hiccups continued for between 1 and 4 days.Twenty-eight of the patients received medication (shitei-decoction,chlorpromazine,metoclopramide,etc.) to relieve hiccups,which was effective in 30% of them.Hiccups developed in patients with osteochondro sarcoma (56%),lung cancer (49%),pancreatic cancer (40%) and esophagus cancer (23%) receiving the following 4 chemotherapy regimens : CDDP+ADM+CAF (56%),CDDP+DTX (50%),CDDP+5 FU (40%),and CDDP+TS 1 (20%) respectively.The CDDP dosage (mg/m2)was higher in patients who had hiccups than in those who had none (80±22 vs 45±33,p< 0.0001)and there was a positive correlation was between CDDP dosage and incidence of hiccups (p<0.001),though all patients developing them received corticosteroids and 5 HT3 antagonists.Multiple logistic regression analysis showed that there were significant differences for the male sex (odds ratio (OR)=8,95% CI=1.5-45.6),CDDP dose (1.03,1.01-1.06),dexamethasone(≥16 mg) (19.4,3.9-95.2)and granisetron (6 mg) (20.9,3-143).We therefore concluded that the independent risk factors influencing the development of hiccups were the male sex and a high dose of CDDP in combination with dexamethasone(≥16 mg),and granisetron (6 mg).

著者

朴 京俊

出版者

Japanese Association of Indian and Buddhist Studies

雑誌

印度學佛教學研究 (ISSN:00194344)

巻号頁・発行日

vol.53, no.1, pp.394-390, 2004-12-20 (Released:2010-03-09)

著者

多田 理恵 内田 輝和

出版者

日本良導絡自律神経学会

雑誌

日本良導絡自律神経学会雑誌 (ISSN:09130977)

巻号頁・発行日

vol.53, no.2, pp.8-10, 2008-03-15 (Released:2019-07-25)

参考文献数

4

著者

西村 恵信

出版者

Japanese Association of Indian and Buddhist Studies

雑誌

印度學佛教學研究 (ISSN:00194344)

巻号頁・発行日

vol.26, no.2, pp.888-891, 1978-03-20 (Released:2010-03-09)

著者

Kazuma DOI Satoshi TANI Toshiyuki OKAZAKI Junichi MIZUNO

出版者

The Japan Neurosurgical Society

雑誌

Neurologia medico-chirurgica (ISSN:04708105)

巻号頁・発行日

pp.2022-0325, (Released:2023-04-06)

参考文献数

16

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Cylindrical cages were known to cause subsidence after anterior cervical discectomy and fusion (ACDF); hence, they were gradually replaced by box-shaped cages. However, this phenomenon has been inconclusive due to limited information and short-term results. Therefore, this study aimed to clarify risk factors for subsidence after ACDF using titanium double cylindrical cages with mid-term follow-up periods. This retrospective study included 49 patients (76 segments) diagnosed with cervical radiculopathy or myelopathy caused by disc herniation, spondylosis, and ossification of the posterior longitudinal ligament. These patients underwent ACDF using these cages from January 2016 to March 2020 in a single institution. Patient demographics and neurological outcomes were also examined. Subsidence was defined as a ≥3-mm segmental disc height decrease at the final follow-up lateral X-ray compared to that on the next day postoperatively. Subsidence occurred in 26 of 76 segments (34.7%) within the follow-up periods of approximately three years. Multivariate analysis using a logistic regression model demonstrated that multilevel surgery was significantly associated with subsidence. The majority of patients achieved good clinical outcomes based on the Odom criteria. This study demonstrated that multilevel surgery was the only risk factor of subsidence post-ACDF with double cylindrical cages. Despite the relatively high subsidence rates, the clinical outcome was almost good at least during the mid-term period.

著者

山口 亮子 Ryoko Yamaguchi

雑誌

法と政治 = The journal of law & politics (ISSN:02880709)

巻号頁・発行日

vol.69, no.2下, pp.33(825)-73(865), 2018-08-30

著者

Yusuke OTSU Sosho KAJIWARA Aya HASHIMOTO Kiyohiko SAKATA Tetsuya NEGOTO Yu HASEGAWA Hideo NAKAMURA Masaru HIROHATA Motohiro MORIOKA

出版者

The Japan Neurosurgical Society

雑誌

Neurologia medico-chirurgica (ISSN:04708105)

巻号頁・発行日

pp.2022-0288, (Released:2023-04-06)

参考文献数

22

被引用文献数

2

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Pharmacotherapy is frequently selected over surgical interventions for late elderly patients with trigeminal neuralgia (TN). However, medication may affect these patients' activities of daily living (ADL). Hence, we investigated the effect of the surgical treatment of TN on ADL in older patients. This study included 11 late elderly patients >75 years old and 26 nonlate elderly patients who underwent microvascular decompression (MVD) for TN at our hospital from June 2017 to August 2021. We evaluated pre- and postsurgical ADL using the Barthel Index (BI) score, side effects of antineuralgic drugs, the BNI pain intensity score, and perioperative medication. The BI score of late elderly patients significantly improved postoperatively, particularly in transfer (pre: 10.5; post: 13.2), mobility (pre: 10; post: 12.7), and feeding (pre: 5.9 points; post: 10 points). Additionally, antineuralgic drugs caused preoperative disturbances of transfer and mobility. Trends of a longer disease duration and frequent occurrence of side effects were observed in all patients in the elderly group, compared to only 9 out of 26 patients in the younger group (100% vs. 35%, p = 0.0002). In addition, drowsiness was observed more frequently in the late elderly group (73% vs. 23%, p = 0.0084). However, the change in scores indicating improvement after surgery was significantly greater in the late elderly group, although both pre- and postoperative scores were higher in the nonlate elderly group (11.4 ± 1.9 vs. 6.9 ± 0.7, p = 0.027). Surgical treatment can improve older patients' ADL because it relieves pain and facilitates discontinuation of antineuralgic drugs. Consequently, MVD can be positively recommended for older patients with TN if general anesthesia is acceptable.

著者

内野 博司 本多 勇介 中島 健太 佐々木 功二 小林 明 田中 江里 久米 信夫 酒井 崇 嶋崎 豊 石川 巌 岡野 信雄 京極 英雄 船越 昭治 北田 嘉一 淵之上 康元 田中 萬吉

出版者

日本茶業学会

雑誌

茶業研究報告 (ISSN:03666190)

巻号頁・発行日

vol.2009, no.107, pp.107_19-107_30, 2009-06-30 (Released:2011-12-09)

参考文献数

5

被引用文献数

1 1

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茶新品種‘ゆめわかば’が埼玉県農林総合研究センター茶業特産研究所で育成された。‘ゆめわかば’は1968年に‘やぶきた’ב埼玉9号’の交配により得られた個体群より選抜され,1994年から2003年に県単試験を含む栄養系適応性試験,裂傷型凍害抵抗性及びもち病抵抗性検定試験を実施し,更に2004年,2005年には香気の更なる発揚を目的に試験を行った。この結果,優秀と認められ,2006年10月17日に茶農林53号‘ゆめわかば’として命名登録,2008年10月16日に品種登録された。‘ゆめわかば’は摘採期が‘やぶきた’より1日から2日遅い中生品種である。生育,収量とも‘やぶきた’並である。耐寒性は赤枯れ抵抗性が「強」,青枯れ抵抗性が「やや強」,裂傷型凍害抵抗性が「強」でいずれも‘やぶきた’より強い。また,病虫害抵抗性は,炭疽病に「やや強」である。製茶品質は外観が優れ,内質も‘やぶきた’並に優れる。また,摘採葉を重量減15%から20%に軽く萎凋させることによって,香気及び滋味が向上する。耐寒性が強いために,関東やそれに類似した冷涼な茶産地に適する。

著者

柴 直樹

出版者

横断型基幹科学技術研究団体連合(横幹連合)

雑誌

横幹連合コンファレンス予稿集 第10回横幹連合コンファレンス

巻号頁・発行日

pp.F-4-3, 2019 (Released:2019-12-16)

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Simulation with agent-based models are used as a method of information systems research. The validity of agent-based models has the perspective which is different from those of traditional simulation approach, and many claims and methods are have been proposed. This paper will summarize them and tries to investigate their effectiveness.

著者

磯田 典和

出版者

獣医疫学会

雑誌

獣医疫学雑誌 (ISSN:13432583)

巻号頁・発行日

vol.25, no.1, pp.1-5, 2021-07-20 (Released:2022-01-19)

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Avian influenza virus is a causal agent of avian influenza, which is belonging to Orthomyxoviridae, and possess the two types of glycoproteins on the surface of a virion; hemagglutinin (HA) and neuraminidase (NA). Based on the reactivity to antiserum, the HA and NA of Type A influenza viruses are classified into H1 to H16, and N1 to N9, respectively. Since 1997, high pathogenicity avian influenza (HPAI), especially caused by the infection of H5HA, had been reported in Asia. Especially, since 2010, H5N8 HPAI viruses (HPAIVs) have been prevalent not only in Asia but also in other regions including Europe and Africa. As of 2020, the H5N8s were further classified into clade 2.3.4.4 according to the amino acid sequence, and H5 HPAIV subclades of a to h in the clade 2.3.4.4 are confirmed. Graduate School of Veterinary Medicine was designated as OIE reference laboratory for highly and low pathogenic avian influenza since 2005 and had conducted several actions including global surveillance of avian influenza. We had already stocked the isolates and developed the genetic database of them (https://virusdb.czc.hokudai.ac.jp).In October 2020, we isolated the H5N8 HPAIV from a fecal sample collected at the Komuke Lake in Hokkaido under the global surveillance, which was designated as A/northern pintail/Hokkaido/M13/2020 (H5N8) (NP/Hok/20). It was revealed that NP/Hok/20 was classified into the H5 clade 2.3.4.4b in the HA of the phylogenetic tree and genetically very close to the H5N8 HPAIV isolated in Europe in the winter of 2019-2020. Furthermore, comprehensive phylogenetical analysis using the H5N8 HPAIV isolated in the Far East in the winter of 2020-2021 revealed that those isolates were classified into three categories including 1) the European isolates in the winter of 2019-2020, 2) the European isolates in the winter of 2020-2021, and 3) isolates in China and Mongolia. Since the genetic reassortment between the European H5N8 isolates and avian influenza viruses in the Asia was confirmed in the phylogenetical analysis, further spread with wider genetic variation might occur.HPAI spread situations in the Europe and Japan in the end of 2020 were similar to ones in the end of 2016; many of the contagious viruses were brought by bird migration from the northern territories. Given the situation that very close viruses were isolated at both edges of the Eurasian continent at the same season, it is likely that the contagious viruses had been already perpetuated in the northern territory where the migratory birds nest in the summer season. Periodic updates of intensive survey at the global level as well as the reinforcement of the biosecurity measures in the poultry farm are essential to prepare for future HPAI outbreak.

著者

松本 五十生 落合 勝義 船越 昭治 中村 公一 真野 光雄 森田 貞夫

出版者

Japanese Society of Tea Science and Technology

雑誌

茶業研究報告 (ISSN:03666190)

巻号頁・発行日

vol.1991, no.74, pp.1-9, 1991-12-10 (Released:2009-07-31)

参考文献数

6

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緑茶の消費向上と嗜好の多様化に対応するため,緑茶にない芳香をもち,苦渋味の少ない新香味茶の製造方法について検討し,図2に示す技術を確立した。(1)萎凋と発酵は煎茶用自動乾燥機を用い,温風温度35~40℃で30分が適当であった(重量減7~10%)。(2)攪拌は中揉機に金網胴をとりつけ,60分処理で好結果が得られた(重量減15%)。(3)静置は生葉コンテナーを用い,室温(27℃)に60分放置した。これにより強い芳香が発揚した。(4)マイクロ波加熱による殺青(ブランチング)は出力4KW,照射時間50秒,重量減45~50%が良好であった。(5)整形及び乾燥は揉捻機,再乾機,乾燥機を用い,揉捻15分,再乾と乾燥はともに60℃の排気温で,それぞれ40分が好適であった。(6)仕上げは火入れを行って青臭みを除き,9号で切断し,10号の篩目で仕分け,整形した(平均粒度1.27mm)。(7)一般消費者に対して,代表的試製茶の嗜好調査を実施したところ,46%の人が好き,やや好きと答えており,市販された場合購買嗜好も高く明るい見通しを得た。

著者

Paula Pontevedra Carlos Lopez-Suarez Veronica Rodriguez Celia Tobar Jesus Pelaez Maria J Suarez

出版者

Japan Prosthodontic Society

雑誌

Journal of Prosthodontic Research (ISSN:18831958)

巻号頁・発行日

pp.JPR_D_22_00237, (Released:2023-03-28)

参考文献数

55

被引用文献数

1

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Purpose: To evaluate and compare the survival, success rates, and biological and technical complications of three-unit posterior monolithic and veneered zirconia and metal-ceramic (MC) posterior fixed partial dentures (FPDs) fabricated using a digital workflow and computer-aided design and computer-aided manufacturing (CAD/CAM) over a 5-year follow-up.Methods: Ninety patients in need of three-unit posterior FPDs were randomized to receive monolithic zirconia (MZ), veneered zirconia (VZ), and MC restorations (n = 30 each). Teeth preparations were scanned using an intraoral scanner, and restorations were milled and cemented with resin cement. Clinical performance and periodontal parameters were assessed at baseline and yearly up to 5 years after insertion. Data analysis was performed using the Kaplan-Meier method, Friedman test, and Wilcoxon signed-rank test with Bonferroni correction and Mann-Whitney U test.Results: The 5-year survival rates of the MZ, VZ, and MC FPDs were 87%, 97%, and 100%, respectively (P = 0.04). Most complications were biological in nature. Only one MZ FPD fractured 58 months after placement. All the restorations were assessed as satisfactory at each recall. Differences were found in the gingival index score over time in the VZ and MC groups. The margin index remained stable throughout the follow-up period in both zirconia groups.Conclusions: The results of this study suggest that using a digital workflow to fabricate posterior FPDs is an adequate treatment option and that monolithic zirconia could be a viable alternative to metal-ceramic or veneered zirconia. However, further long-term studies are necessary to provide stronger evidence in patients with bruxism.

著者

海保 リえ 眞木 俊夫 カイホ リエ マキ トシオ Rie Kiho Toshio Maki

雑誌

紀要

巻号頁・発行日

vol.VOLN3, pp.7-12, 2011-03-01

著者

赤羽根 龍夫 Tatsuo Akabane 神奈川歯科大学

雑誌

基礎科学論集 : 教養課程紀要 = Bulletin of liberal arts and science

巻号頁・発行日

vol.20, pp.1-34, 2002

著者

西田春耕 著

出版者

風俗絵巻図画刊行会

巻号頁・発行日

1919

著者

高橋 史

出版者

一般社団法人 日本認知・行動療法学会

雑誌

行動療法研究 (ISSN:09106529)

巻号頁・発行日

vol.43, no.2, pp.105-114, 2017-05-31 (Released:2017-10-30)

参考文献数

19

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本報告では、価値の明確化と行動活性化を中心とした治療によって症状緩和と生活改善が見られた、出産をきっかけにうつ病となったクライエントの治療経過を報告した。30代女性のクライエントに対して、1回60分、計22回のセッションが実施された。2回目面接において価値のワークが導入され、作成された価値リストに基づいて行動活性化が進められた。治療の結果、抑うつ症状の指標であるBDI-IIは29点から13点、特性不安の指標であるSTAI-Tは58点から38点、心理的柔軟性の指標であるAAQ-IIは19点から30点へと改善した。また、クライエントにとって価値に沿った行動である手料理を作る行動の回数は、1日あたり0.7回から2.1回へと増加した。以上の経過から、産後うつ症状を示すクライエントに対する価値の明確化と行動活性化手続きの併用効果が示された。