著者
Sai YAO Daichi KITAHARA Hiroki KURODA Akira HIRABAYASHI
出版者
The Institute of Electronics, Information and Communication Engineers
雑誌
IEICE TRANSACTIONS on Fundamentals of Electronics, Communications and Computer Sciences (ISSN:09168508)
巻号頁・発行日
vol.E106-A, no.2, pp.106-123, 2023-02-01

The mean, median, and mode are usually calculated from univariate observations as the most basic representative values of a random variable. To measure the spread of the distribution, the standard deviation, interquartile range, and modal interval are also calculated. When we analyze continuous relations between a pair of random variables from bivariate observations, regression analysis is often used. By minimizing appropriate costs evaluating regression errors, we estimate the conditional mean, median, and mode. The conditional standard deviation can be estimated if the bivariate observations are obtained from a Gaussian process. Moreover, the conditional interquartile range can be calculated for various distributions by the quantile regression that estimates any conditional quantile (percentile). Meanwhile, the study of the modal interval regression is relatively new, and spline regression models, known as flexible models having the optimality on the smoothness for bivariate data, are not yet used. In this paper, we propose a modal interval regression method based on spline quantile regression. The proposed method consists of two steps. In the first step, we divide the bivariate observations into bins for one random variable, then detect the modal interval for the other random variable as the lower and upper quantiles in each bin. In the second step, we estimate the conditional modal interval by constructing both lower and upper quantile curves as spline functions. By using the spline quantile regression, the proposed method is widely applicable to various distributions and formulated as a convex optimization problem on the coefficient vectors of the lower and upper spline functions. Extensive experiments, including settings of the bin width, the smoothing parameter and weights in the cost function, show the effectiveness of the proposed modal interval regression in terms of accuracy and visual shape for synthetic data generated from various distributions. Experiments for real-world meteorological data also demonstrate a good performance of the proposed method.
著者
Satoko Notomi Mineaki Kitamura Kosei Yamaguchi Maya Komine Kenji Sawase Tomoya Nishino Satoshi Funakoshi
出版者
The Pharmaceutical Society of Japan
雑誌
Biological and Pharmaceutical Bulletin (ISSN:09186158)
巻号頁・発行日
vol.46, no.2, pp.286-291, 2023-02-01 (Released:2023-02-01)
参考文献数
38
被引用文献数
1

Anorexia is a common symptom in older patients undergoing hemodialysis (HD) and has become a serious problem in dialysis facilities with the aging of patients. Polypharmacy, defined as the prescription of several medications, is known to cause drug-induced anorexia. Although polypharmacy is also common in older patients undergoing HD, only a few studies have examined the association between anorexia and polypharmacy. This study used the Simplified Nutritional Appetite Questionnaire for Japanese Elderly (SNAQ-JE) to evaluate patients’ appetite, and examined its association with medications. This cross-sectional study included 233 patients (aged ≥65 years) who underwent HD in October 2021. Among the 233 patients (median age, 73.0 [interquartile range (IQR), 69.0–80.5] years; men, 57.3%; median dialysis vintage, 62.0 [IQR, 30.0–122.0] months), 116 and 117 were classified into the poor (SNAQ-JE total score ≤14) and good (>14) appetite groups, respectively. Although the total number of medications prescribed was not significantly different between the two groups (p = 0.12), the number of antihypertensive drugs was significantly lower (p = 0.03), and that of sleeping medications was significantly higher (p = 0.002) in the poor appetite group. Multivariable logistic regression analysis showed that the number of sleeping medications was associated with poor appetite (odds ratio, 2.08; 95% confidence interval, 1.32–3.27; p < 0.001). The findings suggest that the number of sleeping medications is an important contributing factor to poor appetite in older patients undergoing HD. A proper and regular review of prescriptions may be necessary to improve anorexia.
著者
Rio Uno Kyoko Ohkawa Honami Kojima Tamami Haraguchi Minoru Ozeki Ikuo Kawasaki Miyako Yoshida Masaaki Habara Hidekazu Ikezaki Takahiro Uchida
出版者
The Pharmaceutical Society of Japan
雑誌
Chemical and Pharmaceutical Bulletin (ISSN:00092363)
巻号頁・発行日
vol.71, no.2, pp.148-153, 2023-02-01 (Released:2023-02-01)
参考文献数
23
被引用文献数
2

This study aimed to evaluate the bitterness of famotidine (FAM) combined with each of three non-steroidal anti-inflammatory drugs (NSAIDs): ibuprofen (IBU), flurbiprofen (FLU), and naproxen (NAP), which have potential as fixed-dose combination (FDC) drugs. We evaluated the bitterness of FAM and each NSAID by taste sensor AN0 and C00, respectively. FAM showed high sensor output representing sensitivity to bitterness, whereas three NSAIDs did not show large sensor output, suggesting that the bitterness intensities of three NSAIDs were lower than that of FAM. The bitterness of FAM on sensor AN0 was suppressed in a concentration-dependent manner when mixed with IBU, FLU, or NAP. Among three NSAIDs, IBU most effectively inhibited bitterness on sensor output, and the gustatory sensation test confirmed that adding IBU to FAM reduced the bitterness of FAM in a concentration-dependent manner. MarvinSketch confirmed that the drugs were mostly present in an ionic solution when FAM was mixed with NSAIDs. The 1H-NMR spectroscopy analysis also revealed the presence of electrostatic interactions between FAM and NSAIDs, suggesting that the electrostatic interaction between FAM and NSAIDs might inhibit the adsorption of FAM on the bitter taste sensor membrane, thereby masking the bitter taste.
著者
西野 範子
出版者
関西大学文化交渉学教育研究拠点(ICIS)
雑誌
周縁の文化交渉学シリーズ1 『東アジアの茶飲文化と茶業』
巻号頁・発行日
pp.163-200, 2011-03-31

ベトナムの窯業村で生産された陶磁器が日本に渡り、茶道という文化的脈略の中で使用された。所謂「安南」と呼ばれるそれらのベトナム陶磁器は、日本において今でも大切に伝世されており、近年では、伝世ベトナム茶陶と同類の陶磁器が発掘調査により出土している。 伝世茶陶および出土資料を包括的に分類し、筆者と西村昌也のベトナム陶磁の分類と編年研究(2005)から、生産年代を比定した。その結果、ベトナム産茶陶の生産年代を、 14世紀、15世紀、16世紀前半、16世紀後半(第3 四半期と第4 四半期)、17世紀前期に分期し、各時期に関する茶陶がもたらされた国際交易の背景について明らかにした。また、朱印船貿易時代には、日本からベトナムへの注文生産が行われていたことが確実で、注文生産の仲介役に、和田理左衛門が関わった可能性ついて文献史と考古学的視点から論証した。
著者
窪田 英樹 石戸谷 裕二 石尾 和央 位下 功
出版者
一般社団法人 日本建築学会
雑誌
日本建築学会計画系論文報告集 (ISSN:09108017)
巻号頁・発行日
vol.384, pp.12-19, 1988-02-28 (Released:2017-12-25)

In order to evaluate ambient temperature for office and house heating, experiments on thermal sensation of bare hands and fingers, and impression of freshness were conducted under the two kinds of clothing condition. Test A: six male subjects selected clothing ensemble to keep thermally neutral sensation. Test B: the subjects wore normal winter clothing. The subjects were exposed for three hours to four ambient temperature conditions of 7°, 10°, 14° and 18℃ for test A and 10°, 14°, 18° and 22℃ for test B. The following results were obtained I the subjects felt their hands and fingers thermally neutral at the ambient temperature of 21℃, which is the lowest ambient temperature for eliminating discomfort due to coolness of bare hands. The subjects felt fresh below the ambient temperture of 20℃, and the authors found that the optimum ambient temperature for freshness was 18℃, accepting slight discomfort of cold hands.
著者
三田寺 裕治
出版者
淑徳大学短期大学部
雑誌
淑徳短期大学研究紀要 (ISSN:02886758)
巻号頁・発行日
vol.52, pp.1-14, 2013-02-25

インシデントデータの収集・分析は事故の原因や再発防止策を検討する上で有効な手段の一つであることが指摘されている。医療分野では、インシデントレポートの電子化が進み、インシデントデータの収集・分析・共有を可能とするレポーティングシステムの開発が行われている。一方、介護分野においては、標準化された報告様式が整備されていないだけでなく、インシデントレポートの電子化が遅れており、紙媒体によってインシデントデータを収集している施設も多く散見される。本研究では、インシデント情報のコード化を行うとともに、インシデントデータを効率的に収集するためのwebブラウザ型のイシデントレポートシステムを開発した。また、開発したインシデントレポートシステムを用いて試行的にインシデントデータを収集し、介護保険施設におけるインシデントの発生状況及びインシデントに関連するリスク要因について検討した。
著者
相馬 輝彦
出版者
中央大学理工学部数学科
雑誌
中央大学数学教室講究録
巻号頁・発行日
vol.5, 2011-03-01

1 0 0 0 OA 死刑と人権

著者
大谷 實 Minoru Oya
出版者
同志社法學會
雑誌
同志社法學 = The Doshisha Hogaku (The Doshisha law review) (ISSN:03877612)
巻号頁・発行日
vol.72, no.1, pp.163-177, 2020-05-31

個人主義に基づく共生社会においては、死刑制度は人権尊重の観点からは廃止すべきであるという観点から、戦後の死刑存廃論の流れを回顧し、実証的根拠が乏しい観念的議論に終始したことを明らかにし、むしろ、極悪非道の罪を犯した人間は死刑になって当然であるという素朴な国民の応報感情ないし世論を改めることが肝心であり、そのためには死刑廃止のための運動団体を結成し、組織的に廃止運動を展開すべきであることを提唱する。
著者
小林 勝法
出版者
文教大学
雑誌
言語と文化 = Language and Culture (ISSN:09147977)
巻号頁・発行日
vol.32, pp.93-111, 2020-03-16

I examined 116 school songs of private universities which I found through their websites or by contacting them, in order to analyze their characteristics. Of them, 110 universities (94%) had established school songs. I obtained and investigated the lyrics of 109 of those by classifying them into the following time periods according to the year they were established:Old system period (1920-1947) : The period of the old school system Expansion period (1948-1988) : The period after World War II, when many universities were establishedHeisei period (1989-2014):The period when the 18-year-old population began to decline, women's colleges became coeducational, and junior colleges became universitiesUpon text mining the lyrics, I found the following characteristics:・In the lyrics, 75 of the university songs included the name of the university (69%), 36 mentioned the founding spirit (33%), and 73 had details including the name and features of the landscape where the university was located(67%).・The words that appeared most often in the lyrics were "my", "our" (246 times)," Oh!" (84 times)," world" (75 times), and "alma mater" (61 times).・Many of the frequently appearing words were common to both the old system and expansion periods which extolled the spirit of young people studying to seek their ideals, bring honor to their alma mater, and make history.・Inspiration, and support for life and school life appeared to be characteristic of university songs in the expansion and Heisei periods with words like “dreams", "friends", and "flowers" appearing often. The trend grew even stronger in the latter period where I observed words like "tomorrow", "future", and "youth". The increasing in the ratio of university admission has changed the university culture and student temperament, and this is reflected in the characteristics of the school songs.
著者
Hong ZHOU Wei LIANG
出版者
The Ornithological Society of Japan
雑誌
ORNITHOLOGICAL SCIENCE (ISSN:13470558)
巻号頁・発行日
vol.22, no.1, pp.93-96, 2023 (Released:2023-01-26)
参考文献数
22

On 13 June 2021, a video was recorded showing an adult female Asian Koel Eudynamys scolopaceus removing three Elliot's Laughingthrush Trochalopteron elliotii nestlings from a nest in a thicket on the banks of Liqiu River in Xinduqiao Town, Kangding, Sichuan, Southwestern China. This is the first record of an Asian Koel removing nestlings from a potential host's nest. Of the various brood parasitism hypotheses, this behavior is most consistent with the farming hypothesis, further suggesting that farming behavior may be a common strategy used by obligate brood parasites.