著者
辻 さつき 神田 玲子
出版者
一般社団法人日本リスク学会
雑誌
日本リスク研究学会誌 (ISSN:09155465)
巻号頁・発行日
vol.18, no.2, pp.2_33-2_45, 2008 (Released:2012-08-22)
参考文献数
15

Risk assessment of technologies and social activities involves subjective judgment as one of its components, which depends on the perception of risk by individuals. In the present study, we undertook a survey of public perceptions regarding the social issues and risks, the images of radiation, and acceptance of its application and health risk.The majority identified global warming as highly risky among social issues related to technology, and smoking among health-damaging issues, but not radiation-related items such as natural radiation, artificial radiation, and X-ray/CT examinations. In general, a sexual distinction was observed regarding perceptions of sick house and food safety. Forty percent of the public inaccurately believed that the main source of daily exposure was nuclear facilities. Many citizens associated the word of radiation with medical exposure, death/damage/disease and nuclear weapon including A.bomb, and connected the health effects of radiation with cancer and leukemia. However, majority did not bring up any image from the terms of “radiation” and “health effects of radiation”
著者
清水 擴
出版者
一般社団法人 日本建築学会
雑誌
日本建築学会計画系論文報告集 (ISSN:09108017)
巻号頁・発行日
vol.389, pp.136-142, 1988-07-30 (Released:2017-12-25)

The purpose of this paper is to make clear the genealogy of the interior decoration of "Amidado" in Heian era. The conclusions are as follows. (1) The sourse of the interior decoration of "Amidado" exists in halls of Hojoji temple. (2) The method of interior decoration was completed in Hoodo, and the other "Amidado" took Hoodo for a model. (3) "Kuhon-ojo-zu" and "Gokuraku-jodo-zu" were the main themes of the interior painting, and several "Hiten", sculpture or painting, were arranged of the upper walls. (4) The first example of the use of "Raden" (mother-of-pearl-work) existed in "Amidado" of Hojoji, and of "Makie" (lacquer) in Tohokuin of Hojoji. (5) Introduction of the painting of "Ryokai-mandara" on the columns is due to belief in "Komyo shingon".
著者
Takaaki Sakai Shinichiro Miura
出版者
The Japanese Circulation Society
雑誌
Circulation Reports (ISSN:24340790)
巻号頁・発行日
pp.CR-19-0018, (Released:2019-07-03)
参考文献数
47
被引用文献数
24

Background:Pathogenesis of heart failure with preserved ejection fraction (HFpEF) may involve endothelial dysfunction and abnormal vascular structure. Sodium-glucose cotransporter 2 (SGLT2) inhibitors have beneficial cardiovascular effects and may improve vascular function in patients with HFpEF.Methods and Results:We recruited 184 patients with type 2 diabetes and HFpEF (mean age, 66.0±14.4 years) who were scheduled for treatment with SGLT2 inhibitors, had transthoracic echocardiogram to identify diastolic function, and flow-mediated dilation (FMD) to evaluate endothelial function, and assessed cardio-ankle vascular index (CAVI) and carotid intima-media thickness as indices of vascular function and vascular structure, respectively. Body weight, systolic blood pressure, diastolic blood pressure, triglycerides, remnant lipoprotein cholesterol, fasting plasma glucose, hemoglobin A1c, urinary albumin/creatinine ratio, and insulin resistance (IR) decreased, hematocrit and FMD increased significantly, and CAVI decreased significantly, after 12-week treatment (P<0.05). Short-term SGLT2 inhibitors improved diastolic function, significantly reducing the mitral ratios of septal E/early septal annular tissue Doppler velocity (P=0.003) and lateral E/early lateral e' (P=0.044). On multiple regression statistically significant associations were seen between ∆mean E/e' and ∆FMD, ∆CAVI, and ∆IR.Conclusions:SGLT2 inhibitors can improve diastolic function in patients with type 2 diabetes, suggesting that current treatment policies for diabetes should be re-examined. Further prospective studies with larger sample sizes could provide mechanistic insights into the benefits of SGLT2 inhibitors.
著者
阿部 雅紀
出版者
日本大学医学会
雑誌
日大医学雑誌 (ISSN:00290424)
巻号頁・発行日
vol.78, no.4, pp.237-241, 2019-08-01 (Released:2019-09-20)
参考文献数
21

慢性腎臓病 (Chronic Kidney Disease: CKD) の食 事療法としてのエネルギー摂取量の設定にあたっては, 目標とする体重とともに,摂取たんぱく質との関係が重 要である.エネルギーは,性,年齢,身体活動レベルな どを考慮するが,25~35 kcal/kg 標準体重/日で指導し, 身体所見や検査所見などの推移により適時に変更する. 過剰なたんぱく質摂取は糸球体過剰濾過を促進し腎機能 に影響を与え,腎機能低下時にはたんぱく質の代謝産物 が尿毒症物質として蓄積する.標準的治療としてのたん ぱく質制限は,ステージ G3a では 0.8~1.0 g/kg 標準体 重/日,ステージ G3b 以降では 0.6~0.8 g/㎏標準体重/日 が推奨されている.たんぱく質制限とともに摂取エネル ギー量も過度に不足すると Protein-energy wasting (PEW) を引き起こす可能性があるため,十分なエネルギー摂取 量を確保することが重要である.CKD においては,高 血圧・尿蛋白の抑制と心血管疾患の予防のため,6 g/日 未満の食塩摂取制限が推奨されている.ただし,過度の 減塩は害となる可能性があるため,3 g を目安として個々 の症例に応じて下限を設定する.血清 K 値は 4.0 mEq/L 以上,5.4 mEq/L 以下で総死亡,心血管疾患の発症リス クが低下する.
著者
上田 祥平 池井 寧 広田 光一 北崎 充晃
出版者
特定非営利活動法人 日本バーチャルリアリティ学会
雑誌
日本バーチャルリアリティ学会論文誌 (ISSN:1344011X)
巻号頁・発行日
vol.21, no.1, pp.15-22, 2016-03-31 (Released:2017-02-01)

We developed a walking recording and experiencing system. For the recording system we captured stereo motion images from two cameras attached to a person's forehead with synchronized data of ankles' accelerations. For the experiencing system we presented 3-D motion images with binocular disparity on a head-mounted display, and presented vibrations to user's soles of feet at the same time. The vibration was made from a footstep sound when a person walked. We found that users subjectively reported that the 3-D motion images with synchronized foot vibrations elicited stronger feelings of walking, leg motion, stepping, and telepresence than without vibrations. These results suggest that our walking experiencing system gives users somewhat active walking feelings.
著者
Yuya Kawano Katsunari Makino Masatoshi Jinnin Soichiro Sawamura Shuichi Shimada Satoshi Fukushima Hironobu Ihn
出版者
International Research and Cooperation Association for Bio & Socio-Sciences Advancement
雑誌
Drug Discoveries & Therapeutics (ISSN:18817831)
巻号頁・発行日
vol.13, no.5, pp.268-273, 2019-10-31 (Released:2019-11-14)
参考文献数
17
被引用文献数
8

Although royal jelly is believed to prevent skin aging, the underlying mechanism is not known in detail. In the present study, we investigated the plausibility of the involvement of microRNAs in the manifestation of this effect of royal jelly. The expression of microRNAs was determined by PCR array analysis and real-time PCR and the number of cells was counted with a cell counter. Using PCR array, we identified four microRNAs that were downregulated by royal jelly in cultured human dermal microvascular endothelial cells (HDMEC). Upon comparison of the expression of the four microRNAs between young and senescent facial skin, miR-129-5p was found to be significantly upregulated in senescent skin. Consistently, the expression of miR-129-5p in HDMEC was significantly increased by UVB radiation, suggesting that this microRNA is related to photoaging. The royal jelly treatment increased the number of HDMEC. Furthermore, forced overexpression of miR-129-5p resulted in significant decrease in the number of HDMEC, and its forced downregulation increased the number of cells. The number and density of vessels is reported to be decreased in aged skin. Our results indicate that miR-129-5p is induced in damaged endothelial cells upon exposure to UV radiation, which decreases the cell number. Furthermore, administration of royal jelly downregulated the expression of miR-129-5p in endothelial cells, and might prevent skin aging by maintaining the number of cells. The present study elucidates the mechanism of vessel aging caused by UV exposure and the anti-aging effects of royal jelly through the involvement of microRNA.
著者
小川 翔大
出版者
一般社団法人 日本教育心理学会
雑誌
教育心理学研究 (ISSN:00215015)
巻号頁・発行日
vol.59, no.3, pp.267-277, 2011 (Released:2012-03-27)
参考文献数
25
被引用文献数
4 1

本研究の目的は, ネガティブな出来事の原因への帰属の違い, 及び同情した人との親密さの違いが同情された時のポジティブ感情やネガティブ感情の生起に及ぼす影響を明らかにすることである。大学生304名を対象に, 病気, 学業の失敗, 対人トラブルに対して同情される話を読んでもらい, 同情された時の様々な感情について評定を求めた。その結果, すべての場面で, ネガティブな出来事の原因を運や他者からの妨害に帰属した人よりも自分自身の能力に帰属した人の方が落ち込み感情が高くなった。また, すべての場面で, 同情した人があまり知らない人の場合よりも親しい人の場合の方が, 喜び感情は高く反発感情は低くなった。以上より, 落ち込み感情はネガティブな出来事の原因帰属によって異なり, 喜び感情と反発感情は相手との親密さによって異なることが明らかになった。
著者
新井 龍一
出版者
公益社団法人 埼玉県理学療法士会
雑誌
理学療法 - 臨床・研究・教育 (ISSN:1880893X)
巻号頁・発行日
vol.26, no.1, pp.59-62, 2019 (Released:2019-05-24)
参考文献数
14

脊柱の変形を伴う右変形性股関節症患者を担当する機会を得た。股関節に対する理学療法を3週間行ったが,歩行時の疼痛がNumerical Rating Scale(以下NRS)4と残存し難渋した。治療内容を再考してシュロス法の治療概念を用いた脊柱に対する理学療法を行い,歩行時の体幹動揺を制御させた結果,12週目で腰椎のコブ角が4°改善した。歩行時の動揺も減少し,14週にはNRS 0へ減少した。脊柱の変形を伴う股関節症患者において,脊柱のアライメントを修正することが股関節の負担軽減に繋がり,さらなる疼痛軽減に効果があることが示唆された。
著者
林 麻子 早坂 格 鈴木 秀久 小林 徳雄 佐々木 聡
出版者
一般社団法人 日本小児腎臓病学会
雑誌
日本小児腎臓病学会雑誌 (ISSN:09152245)
巻号頁・発行日
vol.26, no.1, pp.82-87, 2013-04-15 (Released:2013-10-15)
参考文献数
13
被引用文献数
1

漢方薬の関与が考えられた薬剤性膀胱炎の2例を経験した。症例1は6歳女児。原因不明の肉眼的血尿と頻尿にて当科受診,検尿にて高度蛋白尿が認められた。MRIを含む画像検査にて一部隆起性の膀胱壁肥厚,粘膜肥厚がみられ腫瘍性病変との鑑別を要した。症例2は11歳女児で,2か月間続く血尿と蛋白尿,無菌性膿尿のため当科紹介受診となった。超音波検査にて膀胱壁肥厚を認めた。症例1は柴胡加竜骨牡蠣湯エキスを約3年前から,症例2は温清飲を約1年前から内服しており,両者とも薬剤中止により膀胱炎症状が徐々に改善し,画像検査所見も正常化した。薬剤性膀胱炎は多彩な臨床症状を呈し得る疾患であり,時に画像検査上,腫瘍病変と類似した膀胱の形態異常を示すことがあり,その診断,治療に際して十分に留意すべきであると思われた。
著者
松嶋 達也 大澤 昇平 松尾 豊
出版者
一般社団法人 人工知能学会
雑誌
人工知能学会全国大会論文集 第32回全国大会(2018)
巻号頁・発行日
pp.3A101, 2018 (Released:2018-07-30)

近年,人工知能の活用による社会の生産性向上への期待が高まっている.この期待の背景として,深層学習が人工知能技術のブレイクスルーになったことが挙げられる.しかし,実世界環境で活用可能な人工知能の構築には,いくつかの課題が残されている.特に,観測が部分的であること,タスクに対する報酬の設計が難しいことの2 点が挙げられる. 部分的な観測を扱うニューラルネットワークのモデルとして,注意機構を持つモデルが提案されている.しかし,これらのモデルでは,注意機構の学習がタスクから定義される外的な報酬信号を用いた強化学習によって行われており,外部からの報酬信号が得られない問題設定下では注意機構の学習を行うことができない. 本研究では,注意機構の学習に外的な報酬を用いる代わりに,観測に対する予測の誤差を注意機構の内的な報酬として与え,観測の予測モデルと注意機構を敵対的な学習により訓練する手法を提案する.
著者
大澤 昇平 松尾 豊
出版者
一般社団法人 人工知能学会
雑誌
人工知能学会論文誌 (ISSN:13460714)
巻号頁・発行日
vol.31, no.2, pp.A-F24_1-10, 2016-03-01 (Released:2016-02-18)
参考文献数
22

Success of software developping project depend on skills of developers in the teams, however, predicting such skills is not a obvious problem. In crowd sourcing services, such level of the skills is rated by the users. This paper aims to predict the rating by integrating open source software (OSS) communities and crowd soursing services. We show that the problem is reduced into the feature construction problem from OSS communities and proposes the s-index, which abstract the level of skills of the developers based on the developed projects. Specifically, we inetgrate oDesk (a crowd sourcing service) and GitHub (an OSS community), and construct prediction model by using the ratings from oDesk as a training data. The experimental result shows that our method outperforms the models without s-index for the aspect of nDCG.
著者
石井 雅久 伊東 正 丸尾 達 鈴木 皓三 松尾 幸蔵
出版者
Japanese Society of Agricultural, Biological and Environmental Engineers and Scientists
雑誌
生物環境調節 (ISSN:05824087)
巻号頁・発行日
vol.33, no.2, pp.103-111, 1995-06-30 (Released:2010-06-22)
参考文献数
17
被引用文献数
1

完全制御型植物工場の電力コストを削減させるために, 一般電力と比べて割安な深夜電力 (11pm~7am) の利用について, 『岡山サラダナ』を供試し, 光強度と照射時間の関係から調査・検討を行った.生育中期までは, PPFDならびに照射時間の増加とともに葉の生体重および乾物重は増加したが, 後期から腋芽葉の発生や葉捲きが多く発生し, サラダナの生育は遅延し, 生産物の品質は低下した.また, 1回の明期に照射する光量子の積算値が等しければ, サラダナの生育や品質も同様になると推察された.以上のことから, 本試験の照射条件のなかでは, PPFDが400~420μmol・m-2・s-1, 照射時間が8時間で生育したサラダナが生育や品質などの面から効率的であることがわかり, 深夜電力の利用による栽培の実用的可能性が示唆された.
著者
Masafumi AKISAKA Hidemoto ZAKOUJI Makoto ARIIZUMI
出版者
The Japanese Society for Hygiene
雑誌
Nippon Eiseigaku Zasshi (Japanese Journal of Hygiene) (ISSN:00215082)
巻号頁・発行日
vol.52, no.2, pp.481-489, 1997-07-15 (Released:2009-04-21)
参考文献数
16
被引用文献数
5 4

To obtain basic data on the bone density of high school girls, the bone density of the right heel was measured in principle and their lifestyles were surveyed. The subjects were 142 girls (15-18years, mean±SD=16.5±0.8years old) of a high school in Nagano Prefecture, who accepted our visiting bone health check. Bone density was measured with an' Achilles' ultrasound bone-densitometer (Lunar Co.) and a self-registered questionnaire on their lifestyles was also employed in this study.The main results were as follows:1. There were no significant correlations between Sitffness and, age, grede, bone fracture, family historiy, and regularity of menstruation. However, Stiffness significantly correlated to the age of menophania (r=-0.191, p=0.002)2. High school girls who belonged to a sports club had significantly higher bone density than other girls. Those who did exercises which consist mainly of jumping, had significantly higher bone density than others who participated in running sports or did no exercise. There were also significant differences in the frequency of exercise and the duration of exercise. Mireover, those who had a regular exercise history had higher bone density than those who had no regular exercise histry, and the mean Siffness of the group that did exercises daily was higher than for those who did not.3. There were no significant correlations between Stiffness and food intakes. There also were no significant diffrence for Stiffness concerning intake of calcium-containing food groups. Regarding the cause of weight loss of more than 2kg/month, the mean Stiffness of the group with intense exercise was significantly higher than those in the no-weigh loss group and the group that had reduced dietary intake.4. Regarding the relationships between bone density and the lifestyles of high school girls, a delayed age of menophania had a significantly decreasing effect on Stiffness, whereas three variables of regular exercise habits at present, body weight, and exercise histories had significantly increasing effects on Stiffness in multiple regression analysis.5. It is considered that there may be other important factors in the relationship between bone density and lifestyle of adolescent females who are in a developmental state. Therefore, the measurement of bone density and its assessment need consideration from points of view which are different from those for middle-aged and the elderly people.