著者

Sue Yee LIM Kensuke NAKAMURA Keitaro MORISHITA Noboru SASAKI Masahiro MURAKAMI Tatsuyuki OSUGA Hiroshi OHTA Masahiro YAMASAKI Mitsuyoshi TAKIGUCHI

出版者

公益社団法人 日本獣医学会

雑誌

Journal of Veterinary Medical Science (ISSN:09167250)

巻号頁・発行日

pp.13-0199, (Released:2013-08-13)

被引用文献数

6 17

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Quantitative contrast enhanced ultrasound is a major breakthrough for ultrasound imaging in recent years. However, contrast enhancement of the pancreas is brief with bolus injection. To assess if continuous infusion of Sonazoid® can prolong the duration of pancreatic enhancement over bolus injections, eight adult dogs received bolus injection and continuous infusion of Sonazoid® on separate days. Contrast enhanced ultrasound of the pancreatic parenchyma and proximal descending duodenum was performed, and time intensity curves reflecting tissue perfusions were generated. Perfusion parameters- time to initial upslope, peak time, time to wash-out and peak intensity were calculated and evaluated. Fast wash-in to intense peak, followed by rapid wash-out was observed for time intensity curves of bolus injection. With continuous infusion, contrast wash-in to peak intensity was gradual, followed by long plateau and slow wash-out. Median contrast enhancement durations of the pancreas and duodenum were significantly prolonged by continuous infusion from 11 sec (range, 10 to 23 sec) and 16 sec (range, 3 to 43 sec) at bolus injection to 205 sec (range, 170 to 264 sec, P<0.01) and 193 sec (range, 169 to 216 sec, P<0.05), respectively. Median peak intensity of the pancreas was 100.9 MPV (range, 80.2 to 124.3 MPV) at bolus injection and 77.6 MPV (range, 58.2 to 99.5 MPV, P<0.05) at continuous infusion. Prolonged continuous imaging is afforded by continuous infusion of contrast agent. Peak intensity of the pancreas was slightly diminished in continuous infusion, but offered adequate imaging subjectively.

著者

Dong-In JUNG Hee-Chun LEE Jeongim HA Hae-Won JUNG Joon-Hyeonk JEON Jong-Hyun MOON Jae-Hoon LEE Na-Hyun KIM Jung-Hyang SUR Byeong-Teck KANG Kyu-Woan CHO

出版者

公益社団法人 日本獣医学会

雑誌

Journal of Veterinary Medical Science (ISSN:09167250)

巻号頁・発行日

pp.12-0503, (Released:2013-08-13)

被引用文献数

1 4

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A 4-year-old female Maltese (case 1), a 9-year-old castrated male Shih-Tzu (case 2) and 2-year-old female Pomeranian (case 3) were presented because of neurological signs such as head tilt, ataxia, circling and paresis. Three cases were tentatively diagnosed to meningoencephalitis of unknown etiology based on computed tomography scan and cerebrospinal fluid analysis. All patients were managed with cyclosporine plus prednisolone therapy. The survival times of three patients were 170, 70 and 21 days, respectively. After cases expired, we performed necropsy and histopathological examination for definitive diagnosis. Based on the necropsy, histopathological and immunohistochemical examinations, case 1, 2 and 3 were definitely diagnosed to necrotizing meningoencephalitis, necrotizing leukoencephlaitis and granulomatous meningoencephalitis, respectively. This case report demonstrated that the clinical findings, brain CT characteristics, histopathological and immunohistochemical features of NME, NLE and GME in dogs and discussed about the reason of relatively short survival times under cyclosporine plus prednisolone therapy.

著者

佐々木 常雄 大野 晶子 田中 良明 大島 統男 松原 一仁 牧野 宣一 三島 厚 山口 宏

出版者

公益社団法人 日本アイソトープ協会

雑誌

RADIOISOTOPES (ISSN:00338303)

巻号頁・発行日

vol.25, no.2, pp.94-97, 1976-02-15 (Released:2010-09-07)

参考文献数

4

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131I-adosterol 1mCiを静注し, 投与後7日目, 8日目, 9日目の3日間, 両副腎部を背部からNC (Pho/Gamma III) あるいはON 100シンチカメラによりシンチフォトを撮影する。対象とした副腎疾患はPA 10例, その疑い10例, CS 4例, その疑い3例, Pheo.2例, その疑い11例の40例である。手術によりPA 10例, CS 5例, Pheo. 2例が確認され, いずれもシンチフォト像では高い摂取が病巣に一致して認められた。シンチフォト像で描出された病巣の大きさはPAでは13~27mm, CSでは20~38mm, Pheo.では40mmであった。本検査すなわち副腎シンチグラフィは副腎疾患の診断において血管撮影とともに有効な診断法である。

著者

森田 聡之

出版者

関東社会学会

雑誌

年報社会学論集 (ISSN:09194363)

巻号頁・発行日

vol.1996, no.9, pp.71-82, 1996-06-05 (Released:2010-04-21)

参考文献数

15

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This paper treats requests for ambulance from a corpus of emergency calls (119 calls), which were audio-recorded at a 119 dispatch center during the summer of 1994. In these calls, it is observable that when callers identify themselves, almost all of them use relational terms along with their names, e. g., “ (My name is) Yamada Hanako. wife. ” The question is not why they use such relational terms, but what they do as they use such terms. In order to treat this question, a device-what Harvey Sacks named Membership Catergorization Device-and its use will be considered.

著者

樫田 美雄

出版者

関東社会学会

雑誌

年報社会学論集 (ISSN:09194363)

巻号頁・発行日

vol.1995, no.8, pp.227-238, 1995-06-05 (Released:2010-04-21)

参考文献数

11

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In this paper, some properties of calls for emergency help is considered. The data sets are derived from the audio-taped telephone calls placed to a 119 dispatch center during the summer of 1994. For any hearer of the tapes or reader of the transcribed calls, it is ‘obvious’ that these are calls of emergency, yet, the question remains: How are they accomplished? This paper elucidates three main features of this talk. Firstly, in the topical opening of talk, the dispatch personnel ask the caller for the emergency category relevant to his or her needs, namely “Fire or Ambulance?”. Secondly, in the middle of the talk, both co-conversants confirm paticular relevancies of the emergency call, e.g., “Are there any injured persons?”. Thirdly, in the closing of talk, almost all the dispatchers announce that an emergency vehicle is on the way. Through such practices, members produce 119 talk into a call for help.

著者

神谷 暸

出版者

公益社団法人 日本生体医工学会

雑誌

生体医工学 (ISSN:1347443X)

巻号頁・発行日

vol.49, no.2, pp.324-325, 2011-04-10 (Released:2011-12-14)

著者

大原 美保 目黒 公郎 田中 淳

出版者

東京大学生産技術研究所

雑誌

生産研究 (ISSN:0037105X)

巻号頁・発行日

vol.63, no.6, pp.811-816, 2011 (Released:2011-12-27)

参考文献数

4

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2011年3月11日14時46分に発生した東北地方太平洋沖地震後, 相次ぐ余震活動により緊急地震速報が多数発表され, 住民が速報を見聞きする機会が増えた.本研究では本地震前後での緊急地震速報に対する住民意識の変化について, (1)緊急地震速報の認知度, (2)空振りに対する意識, (3)速報の聞き取り状況, (4)速報を見聞きした場合の対応行動, (5)速報への評価という5つの観点から分析した.この結果, 東日本大震災後, 緊急地震速報の認知度や速報を瞬時に理解する認識力は飛躍的に向上したことがわかった.また, 地震前から緊急地震速報の技術的課題を認識していた場合には空振りへの許容度が高くなった.[本要旨はPDFには含まれない]

著者

遠藤 泰生

出版者

日本政治学会

雑誌

年報政治学 (ISSN:05494192)

巻号頁・発行日

vol.41, pp.131-149, 1991-08-30 (Released:2009-12-21)

著者

Shai HARAN Nobushige KUROKAWA Masato WAKAYAMA

出版者

九州大学大学院数理学研究院

雑誌

Kyushu Journal of Mathematics (ISSN:13406116)

巻号頁・発行日

vol.61, no.2, pp.551-563, 2007 (Released:2008-01-22)

参考文献数

6

被引用文献数

1 2

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This note studies a q-analogue of Mellin's transform of a modular form via Jackson's integral.

著者

神山 泉

出版者

一般社団法人 日本調理科学会

雑誌

日本調理科学会誌 (ISSN:13411535)

巻号頁・発行日

vol.29, no.2, pp.150-154, 1996-05-20 (Released:2013-04-26)

被引用文献数

2

著者

井田 淳 梅本 勝博

出版者

日本NPO学会

雑誌

ノンプロフィット・レビュー (ISSN:13464116)

巻号頁・発行日

vol.3, no.1, pp.37-45, 2003 (Released:2004-01-10)

参考文献数

16

被引用文献数

1

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本稿の目的は,NPOにおける知識の重要性を指摘し,野中の組織的知識創造理論を基にNPOのナレッジ・マネジメントの枠組みを構築することである.NPOの知識創造とは,多数の個人の思いをはっきり言語化してミッションに表現し,それを正当化基準として,新たな知識を創造・実行する中で,社会にその有効性を認知させ,そのミッションを実現していくプロセスである.本研究から,生活者,専門家,利害関係者の持つ知識の活用,開放的な場の設計,ミッションの明確化,知識の蓄積および不足している知識の組織外からの獲得,リーダーに必要なソーシャル・キャピタル,交渉能力,説得能力などが示唆された.また,8項目からなるNPOのナレッジ・マネジメントの実践的方法論も提示した.

著者

永尾 雅哉

出版者

公益社団法人 日本農芸化学会

雑誌

日本農芸化学会誌 (ISSN:00021407)

巻号頁・発行日

vol.71, no.12, pp.1253-1264, 1997-12-01 (Released:2009-02-18)

参考文献数

46

著者

伊藤 通弘

出版者

紙パルプ技術協会

雑誌

紙パ技協誌 (ISSN:0022815X)

巻号頁・発行日

vol.50, no.1, pp.200-200, 1996-01-01 (Released:2009-11-16)

著者

Seiji FUKUMOTO

出版者

(社)日本内分泌学会

雑誌

Endocrine Journal (ISSN:09188959)

巻号頁・発行日

vol.55, no.1, pp.23-31, 2008 (Released:2008-03-13)

参考文献数

52

被引用文献数

39 103

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Fibroblast growth factors (FGFs) are humoral factors with diverse biological functions. While most FGFs were shown to work as local factors regulating cell growth and differentiation, recent investigations indicated that FGF19 subfamily members, FGF15/19, FGF21 and FGF23 work as systemic factors. FGF15/19 produced by intestine inhibits bile acid synthesis and FGF21from liver is involved in carbohydrate and lipid metabolism. In addition, FGF23 was shown to be produced by bone and regulate phosphate and vitamin D metabolism. Furthermore, these FGFs require klotho or βklotho for their actions in addition to canonical FGF receptors. It is possible that these FGFs together with their receptor systems might be targets for novel therapeutic measures in the future.

著者

高桑 徹也 広井 悟 井上 義博 佐々木 盛光 中永 士師明 遠藤 重厚 星 秀逸

出版者

日本救急医学会

雑誌

日本救急医学会雑誌 (ISSN:0915924X)

巻号頁・発行日

vol.4, no.4, pp.350-353, 1993-08-15 (Released:2009-03-27)

参考文献数

9

被引用文献数

1 1

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We report a case of myasthenia caused by a Mamushi (snake)[Agkistrodon halys Blomhoffi] bite. Electromyography revealed a marked increase in the amplitude of action potentials (waxing phenomenon) with fast rates of motor nerve stimulation and the response to tensilon was negative. This case indicates that Mamushi venoms contain a neurotoxin preventing the release of acetylcholine quanta from nerve terminals.

著者

Yuji Furutani Tetsunari Kimura Kido Okamoto

出版者

日本生物物理学会

雑誌

BIOPHYSICS (ISSN:13492942)

巻号頁・発行日

vol.9, pp.123-129, 2013 (Released:2013-08-10)

参考文献数

20

被引用文献数

5 10

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Attenuated total reflectance (ATR)-FTIR spectroscopy has been widely used to probe protein structural changes under various stimuli, such as light absorption, voltage change, and ligand binding, in aqueous conditions. Time-resolved measurements require a trigger, which can be controlled electronically; therefore, light and voltage changes are suitable. Here we developed a novel, rapid buffer-exchange system for time-resolved ATR-FTIR spectroscopy to monitor the ligand- or ion-binding reaction of a protein. By using the step-scan mode (time resolution; 2.5 ms), we confirmed the completion of the buffer-exchange reaction within ~25 ms; the process was monitored by the infrared absorption change of a nitrate band at 1,350 cm-1. We also demonstrated the anion-binding reaction of a membrane protein, Natronomonas pharaonis halorhodopsin (pHR), which binds a chloride ion in the initial anion-binding site near the retinal chromophore. The formation of chloride- or nitrate-bound pHR was confirmed by an increase of the retinal absorption band at 1,528 cm-1. It also should be noted that low sample consumption (~1 μg of protein) makes this new method a powerful technique to understand ligand-protein and ion-protein interactions, particularly for membrane proteins.

著者

Japanese Circulation Society Resuscitation Science Study Group

出版者

日本循環器学会

雑誌

Circulation Journal (ISSN:13469843)

巻号頁・発行日

pp.CJ-13-0457, (Released:2013-08-08)

参考文献数

35

被引用文献数

10 43

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Background: The compression-to-ventilation ratio for basic cardiopulmonary resuscitation (CPR) was changed from 15:2 to 30:2, but there are few human studies comparing chest-compression-only CPR with standard CPR. Methods and Results: From the All-Japan Utstein Registry in the 30:2 CPR era, 173,565 adult cardiac arrests witnessed by bystanders were included. On arrival at the scene, emergency medical services responders assessed the status of dispatcher-assisted CPR instruction and bystander CPR technique (chest compression with or without rescue breathing). The primary endpoint was favorable neurological outcome 30 days after cardiac arrest. The prevalence of dispatcher-assisted CPR instruction increased year by year, contributing to an overall increase of chest-compression-only bystander CPR from 20.6% to 35.0%. Among 78,150 patients receiving bystander CPR, favorable neurological outcome did not differ between dispatcher-assisted and -unassisted CPR (adjusted odds ratio [OR], 1.00; 95% confidence interval [CI]: 0.94–1.08). Chest-compression-only CPR resulted in better favorable neurological outcome than standard CPR in the whole cohort (adjusted OR, 1.09; 95% CI: 1.00–1.18) and in the subgroup with cardiac etiology (adjusted OR, 1.12; 95% CI: 1.02–1.22). The addition of rescue breathing provided no neurological benefit in the non-cardiac etiology subgroup. Conclusions: In the 30:2 CPR era, dispatcher-assisted CPR instruction contributed to an increase of chest-compression-only bystander CPR, supporting the use of chest-compression-only CPR for bystander-witnessed out-of-hospital cardiac arrest in all adults.

著者

林 達郎 周 向栄 陳 華岳 原 武史 藤田 広志 横山 龍二郎 兼松 雅之 星 博昭

出版者

公益社団法人 日本生体医工学会

雑誌

生体医工学 (ISSN:1347443X)

巻号頁・発行日

vol.46, no.4, pp.451-457, 2008-08-10 (Released:2009-01-21)

参考文献数

11

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The number of osteoporosis patients is increasing every year in Japan. Bone mineral density (BMD), which is the helpful feature quantity in diagnosing osteoporosis, is generally measured in the central part of the vertebral body. It's possible to measure BMD at each location in X-ray CT images having a high spatial resolution. If bone mineral density of the vertebral body is not homogeneous, grasp of the lower BMD location inside the vertebral body may be helpful to clinical diagnosis. In this paper, using X-ray CT images of 80 subjects (40 male and 40 female subjects), BMDs of trabecular bones from the 12th thoracic vertebra to the 1th sacral vertebra (S1) were measured at each location. The present study showed that anterior and central locations of thoracolumbar and lumbar vertebra, and posterior, inferior, and central locations of S1 had lower BMD values. Therefore, at the thoracolumbar and lumbar vertebra, if the BMDs of anterior or central locations are selectively measured, prediction of fracture risk at vertebral bodies could be improved.

著者

佐藤 昭夫

出版者

公益社団法人 日本薬理学会

雑誌

日本薬理学雑誌 (ISSN:00155691)

巻号頁・発行日

vol.112, no.supplement, pp.5-9, 1998 (Released:2007-01-30)

参考文献数

31

被引用文献数

2

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Local metabolites have long been considered to play an important physiological role in regulating regional cerebral blood flow (rCBF). However, the evidence reviewed here emphasizes that the regulation of rCBF by central cholinergic nerves is independent of regional metabolism. Activation of the intra cranial cholinergic fibers originating in the nucleus basalis of Meynert (NBM) and septal complex releases acetylcholine in the cortex and hippocampus, which results in vasodilation and an increase in rCBF in the cortex and hippocampus via activation of both muscarinic and nicotinic acetylcholine receptors. Cutaneous sensory stimulation activates the cholinergic nerves originating from the NBM to enhance rCBF. The increase in rCBF at the defuse cortices during walking appears to include an excitation of this NBM-originating cholinergic vasodilation system. Other various inputs to the NBM may have a similar effects to enhance rCBF via activation of that cholinergic system, provided the stimulation is delivered properly. Thus thecombination of pharmacological and nonpharmacological techniques may provide a balance in our attempts to improve cholinergic replacement therapy.

著者

山田 正仁

出版者

一般社団法人 日本内科学会

雑誌

日本内科学会雑誌 (ISSN:00215384)

巻号頁・発行日

vol.97, no.3, pp.575-579, 2008 (Released:2012-08-02)

参考文献数

5