著者
仁科 惣治 日野 啓輔
出版者
一般財団法人 日本消化器病学会
雑誌
日本消化器病学会雑誌 (ISSN:04466586)
巻号頁・発行日
vol.109, no.4, pp.563-570, 2012 (Released:2012-04-05)
参考文献数
38

鉄はFenton反応により活性酸素種を産生し酸化ストレスを惹起する.そのため肝臓の鉄沈着は酸化ストレスを介した肝発癌促進因子とされている.臨床的にも肝内鉄過剰と肝発癌との関連性が指摘されている.典型例としては古くからヘモクロマトーシスと肝発癌の関係が知られているが,より日常的に遭遇する疾患としてC型肝炎,アルコール性肝障害,非アルコール性脂肪性肝炎においても鉄代謝異常が存在することが報告されている.鉄代謝異常の分子機構として鉄吸収のnegative regulatorであるhepcidinの関与なども明らかにされているが,いまだ不明の点も多く,また肝発癌に対するインパクトも今後の研究課題である.
著者
石井 隆之
出版者
近畿大学経済学会
雑誌
生駒経済論叢 = Ikoma Journal of Economics (ISSN:13488686)
巻号頁・発行日
vol.7, no.1, pp.825-847, 2009-07-01

生成文法の枠組みでは, 「経済性」というメタ原理は, 言語を適切に成立させる「原理の原理」とみなされる。 本稿では, このメタ原理としての「経済性」が, 4つの基本的な言語学上の課題,すなわち, 英語の第一人称代名詞の主格が単純であること, 英語の冠詞の存在意義, 日本語において助動詞の種類が豊富な理由, 日本語の数の概念の曖昧さの存在意義に対して, ある程度関わっていることを示した。 結果的に, 経済性は, 言語や状況によって, 形態的コスト・構造的コスト・音声的コストおよび心理的コストのうち1つ, または, 幾つかを低くする方向に働くことが分かった。 (英文) Under the framework of generative grammar, the meta-principle of "economy" is regarded as "the principle of principles," which makes it possible to form a language properly. In this paper, I have shown that economy as the meta-principle is to some extent related to the following four basic linguistic problems: the simplicity of the nominative case of the first-person pronoun in English, the significance of the existence of articles in English, the reason for a variety of auxiliaries in Japanese, and the significance of the existence of vagueness in the concept of numbers in Japanese. It has been found that the "economy" metaprinciple works depending on languages and situations in the way it helps lower one or more of the following costs: morphological cost, syntactic cost, phonological cost and psychological cost.
著者
隅野 美砂輝
出版者
鹿屋体育大学
雑誌
学術研究紀要 / 鹿屋体育大学 (ISSN:13426613)
巻号頁・発行日
vol.60, pp.53-66, 2022-11

Previous studies have revealed that the emotions of sports spectators have an important role in clarifying themechanism of sports spectator behavior. Madrigal (1995) reported that the enjoyment which sport spectatorsexperience while watching a game has a positive effect on their satisfaction. Sumino and Harada (2004; 2005)demonstrated that more emotion such as worry, enjoyment, and pride while watching a game leads to higher teamloyalty, and that more emotion such as pride and anger leads to higher intention to attend future games. On the otherhands, few studies have examined what events or stimuli during the game cause these emotions. The current studyinvestigates what kind of emotions sport spectators have experienced inside/outside the stadium and what kind ofsituation/event elicit these emotions. An interview survey was conducted with J. League spectators. The audio wasrecorded with an IC recorder with the consent of the interviewee, and a verbatim record was created from suchdata. The voice data was 5 hours 10 minutes 43 seconds in total for six people, and the verbatim record was 86,007characters in total. Using the verbatim record, the qualitative data analysis software Maxqda12 was utilized tosegment the factors that caused emotions and generate code names from the bottom up.This study derived the following findings. 1) The emotions associated with watching games at the stadium weregenerated for various scenes, events, and subjects. 2) Some emotions are elicited by the events related to the coreproduct of the service such as the game itself, the teams that the spectator supports, and the results and the play of theplayers who belong to those teams. 3) In the category of anger, the emotions are elicited by unfavorable behavior ofother spectators such as jeering. Practical implications and directions for future research are also discussed.
著者
Saiko Watanabe Ryuzaburo Kanazawa Takanori Uchida Tetsuhiro Higashida Kei Yamazaki Takao Kono
出版者
The Japanese Society for Neuroendovascular Therapy
雑誌
Journal of Neuroendovascular Therapy (ISSN:18824072)
巻号頁・発行日
pp.oa.2022-0048, (Released:2022-11-22)
参考文献数
22

Objective: We aimed to evaluate the usefulness of endovascular embolization for femoral iatrogenic pseudoaneurysms (PAs) following therapeutic and diagnostic neuroendovascular procedures.Methods: This study included 12 patients with femoral PA due to femoral puncture at our department between May 2014 and April 2021. We performed an analysis of baseline characteristics, treatment, and outcome of these cases.Results: Endovascular embolization was performed in 10 of the 12 PAs using coils and/or N-butyl-2-cyanoacrylate. Of these, 10 PAs were treated with endovascular embolization and 9 were successfully occluded, whereas complete occlusion was not achieved in 1 case of PA (success rate: 90%). No new intraoperative or postoperative complications or postoperative recurrences occurred.Conclusion: Endovascular embolization for PA can be immediately performed under local anesthesia without discontinuation of antithrombotic therapy and may be a safe and effective option for access site complication treatment.
著者
村上 カオル 大塚 愛子
出版者
The Japanese Society of Health and Human Ecology
雑誌
民族衛生 (ISSN:03689395)
巻号頁・発行日
vol.23, no.2, pp.55-60,A6, 1957 (Released:2010-11-19)
参考文献数
9
被引用文献数
1

女子の体育においては, 人体美の形成ということが, 目標の一つとして考えられるであろう.従来の顔偏重の弊より腕却し, ようやく全身の均整・調和などの美が叫ばれるようになつたのは当然のことである.最近8頭身という言葉が流行語として通用し, それがあたかも美入の代名詞の如くとり扱われている. 果して8頭身は人体美の規範となるであろうか.ここに先ず, 8頭身の学詮に関し歴史的考察を行うならば, 紀元前5世紀, ギリシアの最盛期において, 有名な彫刻家Polvkleitosが, 人体の均整美に注目し, 以後実測による比較研究を行い, 途に7頭身をもつて入体の最高の構成美となした. その成果は彼の著述にも発表したといわれる. しかしその記述は現在残つていないが, それらの理念にもとすき, 全身の調和律を作つた彼の代表作が「槍をかつぐ人」 (Doryuhoros) だという.これに対し, 8頭身論をとなえたのは紀元前4世紀に活躍したLysipposである. 彼はボリュクレイトスにならい, 人体の計測的比較をなし, 頭部が全身の1/8を示す比例が最も美しいと考えた。彼のApoxyomenos「泥をかき落す青年」といわれる彫刻は, このような規準によりつくられ, 優美軽快な彫刻である.次に, 数字的にも白人の身長及び頭高に関しては, CH. Stratz1) 2) 以来の研究があり, 韓国人の頭部及び躯幹の計測値は景氏によつて明らかにされている4). さらにStratzは日本入についても身体計測を行つている3). 日本人の頭部計測に関しては, 附田氏の日本入頭型の地域差5), 中山氏の近畿地方男子6), 古屋氏の北陸入7) 等の貴重な研究がある. なお西田氏は芸術的な立場から8頭身について述ぺているが, 系統的な測完に基いたものではない8).即ち, 日本人の人体構成要素の比率について系統的な測定をとげたものは, まだ見出されないようである. ここにおいて私達は頭身指数の意義, 並びに年令別・性別の推移を追求し, さらに頭身指数と体力との関係, 手長, 足長身についても測定を行つた.
著者
TAKAHIRO MUKAIMOTO ILLYOUNG HAN TATSUKI NAKA MAKOTO OHNO
出版者
The Japanese Society of Physical Fitness and Sports Medicine
雑誌
体力科学 (ISSN:0039906X)
巻号頁・発行日
vol.55, no.Supplement, pp.S209-S212, 2006-10-01 (Released:2012-09-27)
参考文献数
16
被引用文献数
2 3

15 healthy elderly adults (68.6±4.5 years old) participated in this study and were chosen at random for either super low-velocity repetition training (SLT : n=7) or general low-velocity repetition training (GLT : n=8). All subjects performed machine training leg work twice a week for 6 months. Training contents of SLT and GLT were programmed as follows : SLT (Method : 4 seconds of lifting and 6 sec of lowering) and GLT (Method : 2 sec of lifting and 2 sec of lowering). Muscular strength testing was adopted during isometric knee extension using Cybex6000, and body composition was measured by DXA method. As a result, increases in peak torque values and 5 sec average torques value were significantly different in both groups, pre- and post-training (p<0.05). However, there was no significant difference between the two groups. Fat mass significantly decreased during post-training in both groups (p<0.05); however, there was no significant difference between the groups. SLT showed that increases in maximum muscular strength and endurance were similar to GLT. Thus, low-intensity and low-velocity repetition training is suggested as an effective method for elderly adults to increase lower limb muscular strength.
著者
Toyonobu Tsuda Takeshi Kato Keisuke Usuda Takashi Kusayama Soichiro Usui Kenji Sakata Kenshi Hayashi Masa-aki Kawashiri Masakazu Yamagishi Masayuki Takamura Takayuki Otsuka Shinya Suzuki Akio Hirata Masato Murakami Mitsuru Takami Masaomi Kimura Hidehira Fukaya Shiro Nakahara Wataru Shimizu Yu-ki Iwasaki Hiroshi Hayashi Tomoo Harada Ikutaro Nakajima Ken Okumura Junjiroh Koyama Michifumi Tokuda Teiichi Yamane Yukihiko Momiyama Kojiro Tanimoto Kyoko Soejima Noriko Nonoguchi Koichiro Ejima Nobuhisa Hagiwara Masahide Harada Kazumasa Sonoda Masaru Inoue Koji Kumagai Hidemori Hayashi Kazuhiro Satomi Yoshinao Yazaki Yuji Watari Masaru Arai Ryuta Watanabe Katsuaki Yokoyama Naoya Matsumoto Koichi Nagashima Yasuo Okumura on behalf of the AF Ablation Frontier Registry and the Hokuriku-Plus AF Registry Investigators
出版者
The Japanese Circulation Society
雑誌
Circulation Journal (ISSN:13469843)
巻号頁・発行日
pp.CJ-22-0461, (Released:2022-12-02)
参考文献数
36
被引用文献数
5

Background: A recent randomized trial demonstrated that catheter ablation for atrial fibrillation (AF) in patients with heart failure with reduced ejection fraction (EF) is associated with a reduction in death or heart failure. However, the effect of catheter ablation for AF in patients with heart failure with mid-range or preserved EF is unclear.Methods and Results: We screened 899 AF patients (72.4% male, mean age 68.4 years) with heart failure and left ventricular EF ≥40% from 2 Japanese multicenter AF registries: the Atrial Fibrillation registry to Follow the long-teRm Outcomes and use of aNTIcoagulants aftER Ablation (AF Frontier Ablation Registry) as the ablation group (525 patients who underwent ablation) and the Hokuriku-Plus AF Registry as the medical therapy group (374 patients who did not undergo ablation). Propensity score matching was performed in these 2 registries to yield 106 matched patient pairs. The primary endpoint was a composite of cardiovascular death and hospitalization for heart failure. At 24.6 months, the ablation group had a significantly lower incidence of the primary endpoint (hazard ratio 0.32; 95% confidence interval 0.13–0.70; P=0.004) than the medical therapy group.Conclusions: Compared with medical therapy, catheter ablation for AF in patients with heart failure and mid-range or preserved EF was associated with a significantly lower incidence of cardiovascular death or hospitalization for heart failure.
著者
池川 航史 西島 直
出版者
The Institute of Electronics, Information and Communication Engineers
雑誌
電子情報通信学会論文誌 D (ISSN:18804535)
巻号頁・発行日
vol.J105-D, no.11, pp.653-656, 2022-11-01

本論文における提案手法は,機密データを外部に出すことなく他の組織に利活用させることを可能とする.また,提案手法は秘匿機能をもつスマートコントラクトを活用し,機密データ利活用時の手続き情報に関しても秘匿化を実現する.