著者
Jung Min Choi Seung-Hwa Lee Yu Jeong Jang Mira Kang Jin-Ho Choi
出版者
The Japanese Circulation Society
雑誌
Circulation Journal (ISSN:13469843)
巻号頁・発行日
pp.CJ-20-0966, (Released:2021-03-31)
参考文献数
29
被引用文献数
3

Background:Non-compliance with angiotensin receptor blockers (ARB) or statin is one of the major hurdles to optimal medical treatment. This study investigated whether fixed-dose combination (FDC) improved compliance to medication compared with traditional free combination (FC).Methods and Results:In this retrospective nationwide cohort study, medication persistency, medication adherence measured by proportion of days covered (PDC), and all-cause death of 123,992 patients who started ARB and stain were investigated for 540 days. Patients had a mean age of 63 years and 48% were male. Persistency, PDC, and proportion of PDC ≥80% of FDC (N=34,776) were higher than those for FC (N=89,216) in both unadjusted analysis (54.5% vs. 27.8%; 84.1% vs. 63.1%; 75.5% vs. 48.1%) and propensity-score matched analysis (P<0.001, all). Death risk for the investigation period (0–540 days) was lower in FDC in unadjusted (1.8% vs. 2.6%, P<0.001) and adjusted cohort (P<0.05). In landmark analyses at days 180 and 360, there was no significant difference of death risk between FDC and FC (P>0.05).Conclusions:In this real-world data analysis, patients taking FDC of ARB and statin showed higher medication persistence and adherence compared to patients taking FC of ARB and statin up to 540 days. The risk of all-cause death was not different between FDC and FC despite better medication compliance in the FDC patients.
著者
桝本 妙子 山田 陽介 山田 実 中谷 友樹 三宅 基子 渡邊 裕也 吉田 司 横山 慶一 山縣 恵美 伊達 平和 南里 妃名子 小松 光代 吉中 康子 藤原 佳典 岡山 寧子 木村 みさか
出版者
日本公衆衛生学会
雑誌
日本公衆衛生雑誌 (ISSN:05461766)
巻号頁・発行日
vol.62, no.8, pp.390-401, 2015 (Released:2015-10-27)
参考文献数
43
被引用文献数
6

目的 地域在住自立高齢者の転倒リスクとその関連要因および性差を検討した。方法 京都府亀岡市の65歳以上の全高齢者の中で要介護 3 以上を除く18,231人に対して2011年 7~8 月に行った自記式留め置き式質問紙調査への回答者13,159人のうち(回収率72.2%),要支援・要介護認定者を除く「自立高齢者」12,054人について分析した。調査票は個別に配布し郵送で回収した。調査内容には,基本属性,鳥羽らによる転倒リスク簡易評価指標 5 項目,日常生活圏域ニーズ調査基本チェックリスト25項目,老研式活動能力指標13項目を用い,高齢者の諸機能や生活機能の低下の有無を示す 9 つの指標(①運動機能,②低栄養,③口腔機能,④閉じこもり,⑤物忘れ,⑥うつ傾向,⑦ IADL,⑧知的能動性,⑨社会的役割)で調査した。分析は,性,年齢別の転倒リスクとその関連要因および性差をカイ二乗検定とロジスティック回帰分析により把握し,9 つの評価指標を独立変数,年齢と教育年数を共変量,転倒リスクを従属変数とするロジスティック回帰分析(ステップワイズ法)を行って各要因による転倒リスクへの独立した影響を性別ごとに分析した。結果 本調査回答者の過去 1 年間の転倒率は20.8%で,転倒リスク高群は26.6%であった。転倒リスクは,男女とも加齢とともに高くなり,女性はすべての年齢層において男性よりも高かった。また,男女とも,すべての評価指標と転倒リスクとの関連がみられ,それぞれの要因を調整した結果では,男性は運動機能,低栄養,口腔機能,物忘れ,うつ傾向,IADL に,女性は運動機能,口腔機能,物忘れ,うつ傾向,IADL に有意な関連がみられ,運動機能低下は男女とも最も強い要因であった。性差では,低栄養,口腔機能は男性の方に,IADL,知的能動性は女性の方に転倒リスクとの関連が強かった。結論 地域在住自立高齢者の 5 人に 1 人は過去 1 年間に転倒を経験し,4 人に 1 人は転倒リスクを有していた。転倒リスクと 9 つすべての評価指標との間に有意な関連がみられ,とくに男女とも運動機能低下が最も大きかった。また,転倒リスクに影響する要因に性差がみられ,性別を考慮した支援策が必要と示唆された。

1 0 0 0 OA 朝鮮開化史

著者
恒屋盛服 著
出版者
博文館
巻号頁・発行日
1901
著者
飯島 一彦
出版者
国学院大学出版部
雑誌
国学院雑誌 (ISSN:02882051)
巻号頁・発行日
vol.94, no.3, pp.p28-40, 1993-03
著者
兼岩 尭希 中村 剛士 加納 政芳 山田 晃嗣
出版者
Japan Society for Fuzzy Theory and Intelligent Informatics
雑誌
知能と情報 (ISSN:13477986)
巻号頁・発行日
vol.32, no.5, pp.907-911, 2020-10-15 (Released:2020-10-15)
参考文献数
5
被引用文献数
1

擬音語・擬態語の総称であるオノマトペは,音象徴性を持つとされる.音象徴とは,特定の音が特定のイメージを喚起する事象であり,類似した特定の音は類似した特定のイメージを喚起できると考えられる.浦田らは,この音象徴性に基づいて,オノマトペの意味の類似関係をオートエンコーダの中間層によって可視化するオノマトペ・シソーラス・マップを提案した.このマップ上の局所的な位置関係は,オノマトペ間の意味的な類似関係を概略的に表すことができると報告されているが,音象徴の可視化に関して評価が十分なされたとは言い難い.本研究では,音象徴に関する言語学的知見を元に仮説を設定し,マップの可視化能力について検証を行った.検証実験の結果,マップは仮説をある程度支持するものの,一部については仮説と異なる結果が得られた.
著者
田中 康一
出版者
人文地理学会
雑誌
人文地理 (ISSN:00187216)
巻号頁・発行日
vol.47, no.5, pp.417-438, 1995
被引用文献数
2 1

The author's purpose was to elucidate the mechanisms of the location and transfer of the headquarters of an enterprise.The author did a case study on an enterprise and used several kinds of numerical indicators and written statements from annual financial reports, corporate history book and other materials about the enterprise to explain the reasons for and the processes of the location and transfer of functional departments of its corporate headquarters, including those for purchasing, production control, sales, personnel, finance, general accounting, planning, general affairs, and the strategic decision making, with the help of theories of business management.For example, the transition of the financial ratios and the spatial distribution of financial sources of the enterprise were used to explain the location and transfer of its Finance Dept. and the transition of the spatial distribution of labor was used to explain those of its Personnel Dept.The implications resulting from the analysis of the differences and similarities between the transferring processes of those functional departments greatly helped to extract some common and important rules for the location and transfer of functional departments of the corporate headquarters.In this empirical analysis, Snow Brand Milk Products Co., Ltd. (founded in 1925), Japan's largest dairy products company, was selected as a case study.The main reasons for choosing this enterprise were the abundant data concerning its financing and location since its foundation, and its experience in transferring its headquarters from the city of Sapporo, the largest city of Hokkaido, the northernmost of Japan's four main islands, to the capital city of Tokyo, the location of the nation's largest money market, most of the headquarters of the nation's largest banks and of other private and/or public organizations, the most important market for selling products, and the location with the most efficient access for transportation, communication and information processing.The facts found in the empirical study are summarized as follows:1. Until the company established its management base in the Hokkaido area, its financing depended on the local financial institutions and its Finance Dept. was located in Sapporo. But, as the company gradually expanded its operational space nationally, the volume of financial demand dramatically increased and came to depend on large financial institutions based in Tokyo and finally the Finance Dept. was transferred to Tokyo. Its gradual transfer started in 1958, just before the company started its nation-wide expansion, and took about two years to finish. Simultaneously, the transfer of the General Accounting Dept., the Planning Dept., and the Board of Directors occurred.2. As the locations of its plants and sales offices expanded nationally, the distribution of its labor also dispersed nationally. Accordingly the Production Control Dept. and the Personnel Dept., transferred to Tokyo, seeking for the most efficient access infrastructure to secure a national scale of transportation, telecommunication and information processing. As for the Personnel Dept., its gradual transfer started in 1958 and took more than seven years to finish and for Production Dept. about 10years, while the Sales Dept. had been located in Tokyo since the foundation of the enterprise.3. The General Affairs Dept. transferred following the locational shift of other departments.4. These transferring processes all involved a gradual transfer of authority from Sapporo to Tokyo and a spatial division of business management/administration both between and within functional departments was observed.Possible rules for the location of the functional departments based on the facts above are as follows:1. The location of a corporate headquarters is subject to the location of its functional departments.
著者
中村 邦彦
雑誌
あたらしい眼科 = Journal of the eye (ISSN:09101810)
巻号頁・発行日
vol.25, no.3, pp.331-332, 2008-03-30
被引用文献数
1
著者
Son Thanh NGUYEN Tsuyoshi TAKAHASHI Ayahisa OKAWA Hisayuki SUEMATSU Koichi NIIHARA Tadachika NAKAYAMA
出版者
The Ceramic Society of Japan
雑誌
Journal of the Ceramic Society of Japan (ISSN:18820743)
巻号頁・発行日
vol.129, no.4, pp.209-216, 2021-04-01 (Released:2021-04-01)
参考文献数
33
被引用文献数
12

In the emerging era of aircraft industry, silicon carbide (SiC) is regarded as an appropriate material for gas turbine engine blades. In order to protect this ceramic component against the oxidation and volatilization in hot steam environments, environmental barrier coating should be utilized. The composite of SiC/Yb2Si2O7–Yb2SiO5 with self-healing ability is a candidate for the top layer of this coating. In this study, the crack-healing behavior of SiC/Yb2Si2O7–Yb2SiO5 nanocomposites is investigated by pre-cracking followed by annealing in oxidizing environments. Comparing to previous studies, the healing time and healing temperature can be reduced to 15 min and 800 °C by increasing the volume fraction of SiC to 20 %. In addition, nanocomposites with both self-healing ability and superior strength were created in this research by combining two types of SiC filler (whiskers and nanoparticulates). The self-healing mechanism in these composites is the SiC oxidation and silicate transformation associated with their volume expansion, which is evidenced by X-ray diffraction and scanning electron microscope. According to the results, the best volume ratio between whisker and nanoparticulate is determined as 1/3.
著者
旭 浩平 森 海里 中山 雅人 西浦 敬信
出版者
The Institute of Electronics, Information and Communication Engineers
雑誌
電子情報通信学会論文誌 D (ISSN:18804535)
巻号頁・発行日
vol.J104-D, no.4, pp.186-197, 2021-04-01

パラメトリックスピーカは,音響信号の振幅によりキャリアと呼ばれる超音波を変調した振幅変調波を大音圧で放射することで超指向性を実現する.振幅変調波を放射すると,空気の非線形性により,音響信号が自己復調する.しかしながら,パラメトリックスピーカは空気の非線形性に基づいて音響信号を復調しているため,復調音の音圧が小さい.また,パラメトリックスピーカから振幅変調波を長時間放射することにより,超音波素子の疲労破壊が発生し,周波数ピーク雑音が発生する.そこで,本論文ではアドバンスドキャリアを用いてこれら問題を解決する手法を提案する.アドバンスドキャリアとはパラメトリックスピーカのもつ各問題点を解決するための最適なキャリアであり,キャリアの波形や周波数を目的に合わせて制御する特徴をもつ.具体的には,復調音の音圧を改善するために,キャリアの波形がもつエネルギーを増幅した矩形アドバンスドキャリアを最初に提案する.次に,周波数ピーク雑音を低減するために,キャリア周波数が超音波素子の共振周波数を中心に時間遷移する周波数アドバンスドキャリアを提案する.評価実験の結果,各提案手法の有効性を確認した.
著者
俵 希實
出版者
社会学研究会
雑誌
ソシオロジ (ISSN:05841380)
巻号頁・発行日
vol.51, no.1, pp.69-85,210, 2006-05-31 (Released:2016-03-23)
参考文献数
29

Since the mid-1980s, the number of Japanese-Brazilian immigrants to Japan has continued to increase. Various urban and regional studies have been conducted in certain residential areas where these Japanese-Brazilian immigrants to Japan are living. The issues discussed in these studies, specifically 1)the development of Japanese-Brazilian communities and networks, 2)interpersonal and inter-group relations between Japanese-Brazilian immigrants and local Japanese residents and 3)the length of residence in Japan have all been designated as "the development of lifestyle after immigration" for the purpose of this study. Previous studies have found that the development of lifestyle varied by residential area. However, these studies have been based almost exclusively on case studies from areas of Japan with high concentrations of Japanese-Brazilian immigrants, and have relied extensively on explanations from the perspective of community studies. Therefore, in order to study more specific factors contributing to the differential conditions of Japanese-Brazilian immigrants' lifestyle development in various residential areas in Japan, and to provide an analytical framework for more comprehensive discussion, this study collected data through case studies and questionnaires in Komatsu City, Ishikawa Prefecture, where relatively few Japanese-Brazilians reside. This study also compared Komatsu with other previously studied areas with regarding to a few specific factors, and found that the development of Japanese-Brazilian communities and networks in Komatsu was comparatively weak. In addition, relations with the local Japanese residents were limited, and the length of residence was generally shorter than in the areas previously studied. This study concludes that the differences in conditions found in various residential areas can be partially attributed to the following three factors; the local concentration of Japanese-Brazilian immigrants, local differences in the immigration process, and variations in local labor markets.
著者
中村 隆治 藤井 英二郎
出版者
社団法人 日本造園学会
雑誌
造園雑誌 (ISSN:03877248)
巻号頁・発行日
vol.55, no.5, pp.139-144, 1991-03-31 (Released:2011-07-19)
参考文献数
2
被引用文献数
18 24

緑地の視覚心理的効果を明らかにするために, 本実験では生垣, ブロック塀, さらに緑量的にそれらの中間的な段階の視覚対象として樹木とブロックの比が2:5, 4:3, 5:2となる場合の5つの対象物をみたときの脳波, 特にα波β波について分析を行った。 その結果, α波とβ波の合計値に占めるα波の割合が, ブロックに対する樹木の割合が半分以上になると高くなる傾向を示した。 一般に, 安静時にはα波が増え, 緊張時にはβ波が増えると言われていることから, この傾向はブロックが緊張感をもたらし, 樹木はそれを和らげる効果があることを示唆するものであることが明らかになった。