著者
高村 好実
出版者
一般社団法人 日本臨床衛生検査技師会
雑誌
医学検査 (ISSN:09158669)
巻号頁・発行日
vol.66, no.J-STAGE-2, pp.22-38, 2017-08-31 (Released:2017-09-06)
参考文献数
8

画像検査はその機器が高額であることや専門の撮像技術が必要なこと,さらに放射性同位元素を用いることなど,一般的な検査として施行するには多くの条件が必要であり,認知症の診断や治療を行う全ての施設において実施できるものではない。しかし,近年の撮像技術の進歩により脳の器質的変化は高い精度と分解能で画像化でき,脳の萎縮の程度については数ミリ単位での描出が可能となり,その有用性は従来にも増して高まっている。また,脳の機能撮像においても早期アルツハイマー型認知症診断支援システム(Voxel-based Specific Regional analysis system for Altheimer’s Desease; VSRAD)やメタヨードベンジルグアニジン(3(meta)-iodobenzylguanidine; MIBG)心筋シンチグラフィーは精度が高くなり,最近では認知症の原因とされているアミロイドやタウを測定し,認知症症状が出現する前の異常蛋白を捉えることも行われている。今後画像検査は早期発見から診断,治療からフォローにおいて増々その有用性が高まることが期待されている。この章では,認知症における各種画像検査について簡単な解説を加えるとともに,各認知症における各画像診断についての説明をする。
著者
安田 泰久 丸山 淳一 丹羽 太左衛門
出版者
日本養豚学会
雑誌
日本養豚研究会誌 (ISSN:03888460)
巻号頁・発行日
vol.5, no.3, pp.119-125, 1968-12-31 (Released:2011-06-08)
参考文献数
37

豚精液および精漿で家兎を免疫して, それに対して産生した抗体を用いて, 精液および精漿の抗原系の追求を行なった。1) 沈降素抗体価は, 免疫後1週目から精液および精漿の抗体産生が認められ, 2週目においては10:1×29以上の抗体価を示した。また, 精液は精漿よりも抗原性の高いことが認められた。2) OUCHTERLONY 法で抗原系を検討した。a. Landrace 種と Yorkshire 種において, 精液には抗原系の差が認められなかった。しかし, 精漿においては沈降線の出現部位と出現時間に差が認められた。b. 精液の分離時において各々の遠心速度によって得た精漿の抗原系には差が認められなかった。c. 雄性生殖腺液の抗原系において, 精巣上体精液の抗原系は弱く, 数も少なかった。しかし, 精のう液の抗原系は強く, 抗原系の数も多いことが認められた。豚精液の主要な抗原成分は精のう液に由来するものと考えられる。
著者
仲野 里香 菊池 良和
出版者
日本音声言語医学会
雑誌
音声言語医学 (ISSN:00302813)
巻号頁・発行日
vol.57, no.1, pp.32-40, 2016 (Released:2016-02-23)
参考文献数
22
被引用文献数
1

吃音の悩みをきっかけに「不登校準備段階」の状態を呈し,「吃音をゼロにしたい」と当院を受診した13歳中学1年生男児に対して,直接的な発話訓練と多因子モデルに基づいた認知行動療法的アプローチを同時に行った.直接的な発話訓練は,軟起声・構音器官の軽い接触・弾力的な発話速度・随伴症状に対する訓練を中心に実施した.認知の修正に対しては,吃音の知識・自己評価・目標・発話体験を記録する「吃音ノート」を独自に作成して使用した.3ヵ月全11回の治療で吃音は軽快し,不登校に陥ることなく学校生活が楽しめるようになった.直接的な発話訓練と同時に多因子モデルに基づいた認知行動療法的アプローチを実施することは,「不登校準備段階」にある中学生に有効であることが示唆された.
著者
原山 智 高橋 正明 宿輪 隆太 板谷 徹丸 八木 公史
出版者
一般社団法人 日本地質学会
雑誌
地質学雑誌 (ISSN:00167630)
巻号頁・発行日
vol.116, no.Supplement, pp.S63-S81, 2010 (Released:2012-01-26)
参考文献数
28
被引用文献数
2 7

飛騨山脈の北半部中央を南から北へ流下する黒部川の流域はいまだ踏査の行われていない地域が残る地質学的秘境の状態にある.近年に至っても様々な発見が相次いできており,その代表的な例が第四紀黒部川花崗岩の発見である.黒部川花崗岩は黒部川右岸中流域の祖母谷温泉から黒部ダム- 扇沢にかけてバソリスとして露出している.黒部川流域は日本国内ではもっとも多数の花崗岩貫入時期が確認される地域であり,ジュラ紀(190 Ma 前後),白亜紀前期末(100 Ma 前後),白亜紀後期初頭(90 Ma),白亜紀後期末(70 Ma前後),古第三紀初頭(65-60 Ma),鮮新世初頭(5 Ma),鮮新世(3 Ma),第四紀更新世前期(2-1 Ma)の貫入ユニットが確認できる.この流域には源頭部から黒部川扇状地に至るまで多数の温泉や地熱地帯が知られており,祖母谷,黒薙地域には80℃を超える高温泉がある.また黒部峡谷鉄道の終点,欅平から名剣温泉にかけてはマイロナイト化した花崗岩類中に熱変成した結晶片岩類が捕獲され,その帰属が議論されてきた.本見学旅行では,飛騨山脈の形成という視点で黒薙・鐘釣・祖母谷の温泉と,欅平-祖母谷温泉間の鮮新世-更新世の花崗岩および剪断帯を取り上げ,観察する.
著者
中村 英次郎 井口 竹彦 中村 太郎 山田 秀大 七森 和久 酒井 祐一 林 義裕 畑田 和男
出版者
West-Japanese Society of Orthopedics & Traumatology
雑誌
整形外科と災害外科 (ISSN:00371033)
巻号頁・発行日
vol.47, no.2, pp.704-707, 1998-03-25 (Released:2010-02-25)
参考文献数
9

Five cases of the fracture of the sternum due to use of a seat belt were reported. According to the Fowler's classification, our cases were classified as TYPE: 1 case, Type IV: 3 cases and Type VIII: 1 case. With regard to four cases (type I and IV), the mechanism of the fracture was direct violence.A case associated with the injuries of interspinal ligaments of the thoracic spine, the mechanism of the fracture was indirect violence as flexion-compression injury. All cases were treated with rest and immobilization. The importance of radiographic examination on the sternum in patient of seat belt injury.
著者
小山内 早織 菅谷 奈津恵
出版者
日本語教育方法研究会
雑誌
日本語教育方法研究会誌 (ISSN:18813968)
巻号頁・発行日
vol.25, no.2, pp.72-73, 2019 (Released:2019-07-02)
参考文献数
3

This study observed the usage of the sentence final particle ne by a Taiwanese learner of Japanese. It focused on ne's frequency and function. The research was carried out over 6 months through LINE conversation once a week and an oral conversation once after six LINE conversations. Analysis revealed that oral conversation did not show changes while LINE conversation showed some changes in frequency and function. Notably, in the third term soudesune may have been used as a chunk. In addition, the usage of sone rapidly increased in the fourth term perhaps due to having more input and opportunities to use it.
著者
中村 かおり 向井 留実子 近藤 裕子
出版者
日本語教育方法研究会
雑誌
日本語教育方法研究会誌 (ISSN:18813968)
巻号頁・発行日
vol.25, no.2, pp.26-27, 2019 (Released:2019-07-02)
参考文献数
7

As part of a Japanese language academic writing class for international graduate students, a trial activity to enhance the understanding of the use of references in specialized fields was used. The students considered the placement and purpose of citations and how they were introduced in papers in their own fields of study and responded to questions about what they found. Their responses showed that, through this activity, they gained not only a better understanding of the use of references, but their understanding of the content of the paper deepened and they were better able to evaluate the paper. It appears that this activity can be effective with a class of students from different fields.
著者
高橋 阿貴
出版者
日本動物心理学会
雑誌
動物心理学研究 (ISSN:09168419)
巻号頁・発行日
pp.62.2.5, (Released:2012-12-28)
参考文献数
68

This review is an introduction to a recently developed technology “optogenetics” that allows researchers to directly manipulate the activity of aimed neurons with millisecond (ms) order in a behaving animal. Two types of microbial opsin, channel rhodopsin 2 (ChR2) and halorhodopsin (NpHR), are commonly used as the tools for optogenetics. ChR2 responds to blue light to induce neuronal firing via cation influx, whereas NpHR responds to yellow light to inhibit neuronal activity via Cl- influx. This review first introduces these and other opsins that have been used for optogenetics. Next, three methods to introduce these foreign genes into mouse nervous system are going to be explained: 1) viral infection, 2) in utero electrophoresis, and 3) transgenic mouse. Then, this review illustrates how neuron-type specific expression of the opsin gene can be achieved, and also how the optic stimulation of opsins that expresses in the deep brain structure can be accomplished. Finally, how the optogenetic technique has been used for behavioral neuroscience will be discussed by focusing on the studies about amygdala microcircuit that mediates conditioned fear.
著者
Shinji Sato Yoichi Kawanishi Masayuki Ide Noriko Sodeyama Hitoshi Takei
出版者
The Japanese Society of Clinical Neuropsychopharmacology
雑誌
Clinical Neuropsychopharmacology and Therapeutics (ISSN:18848826)
巻号頁・発行日
vol.10, pp.26-28, 2019-11-08 (Released:2019-11-08)
参考文献数
12
被引用文献数
1

Autism spectrum disorder (ASD) includes disturbances in communication, imagination, and social interaction. In individuals with ASD, selective mutism is a common symptom of a communication disability. Selective serotonin reuptake inhibitors (SSRIs) have been recommended to treat selective mutism, especially after psychosocial interventions fail. However, the mechanism and efficacy of SSRIs in treating selective mutism remain unclear. Here we report the case of an adult male with ASD whose selective mutism was improved by aripiprazole but not SSRIs. To the best of our knowledge, this is the first such case report. We believe that our patient's case highlights the value of differentiating between psychopathology and psychopharmacology when examining ASD symptoms.
著者
栗田 康之
出版者
経済理論学会
雑誌
季刊経済理論 (ISSN:18825184)
巻号頁・発行日
vol.47, no.4, pp.30-41, 2011-01-20 (Released:2017-04-25)

It has been often pointed out that Kalecki's political economy was based on that of Marx. For example, T. Kowalik and J. Robinson referred to the Marxian roots of Kalecki's political economy. They emphasized that Kalecki's theory of effective demand was based on Marx's scheme of reproduction, and, at the same time, gave a solution to 'the problem of the realization of surpuls value' in the third volume of Capital. However, only a few studies have been done to explore the relationship between Kalecki's theory of effective demand and Marx's scheme of reproduction. First of all, in this paper, we survey Kalecki's referrance to Marx's scheme of reproduction and Kalecki's own scheme. Kalckie often refered to Marx's scheme of reproduction, and, at the same time, modified the Marx's scheme: he formulated his own scheme ("tableau economicue of the nationl income"). In his scheme, Kalecki divided the economy into two sectors (the investment goods sector and the consumption goods sector) or three sectors (the consumption goods were subdivided into for workers and for capitalists), and he assumed that each department represents "the integrated production" of the final products. Moreover, Kalecki asssumed, "as Marx does", that workers do not save. Then, he arrived at "the fudamental Marxian 'equation of exchange'" (C_1=S_2 or P_3=W_1+W_2). The "fudamental Marxian 'equation of exchange'" is just the equation of the balancing condition in Marx's scheme of expanded reproduction. From this "fudamental Marxian 'equation of exchange'," Kalecki derived the proposition that investment and capitalst consumption determin profits. Second, we compare Kalecki's theory of capitalist economy with that of Marx in Capital, especialy in the third volume of Capital, in order to clarify the theoretical relationship of them. Kalecki succeeded to the Marxian concept of class, the capital-labour relation. For Kalecki, capitalists are owners of money and the means of production, and workers do not save. But he rejected the Marxian theory of value and the theory of surplus-value. He never dealt with such Marxian concepts of labour value, surplus value and price of production. On the other hand, he emphasized the oligopolitic nature of the capitalist economy and the realization of profits in the process of circulation i. e. in the product market. Coseqently, he could derive the proposition that investment and capitalst consumption determin profits, and, at the same time, give a solution to 'the problem of the realization of surpuls value'. However, on the other hand, he neglected the reduction in cost and the formation of the relative surplus population (industrial reserve army) by the technical change in the process of production. It is necessary and possibie to integrate Kalecki's theory of effective demand in his scheme ("tableau economicue of the nationl income") with marx's theory of surpuls value. From this point of view, we need to integrate Kalecki's political economy with that of Marx.
著者
入江 由香子 小笠原 正志 吉田 裕人
出版者
Japan Society of Sports Industry
雑誌
スポーツ産業学研究 (ISSN:13430688)
巻号頁・発行日
vol.28, no.4, pp.4_345-4_355, 2018 (Released:2018-10-12)
参考文献数
36
被引用文献数
1

The purpose of this study was to examine the business model of sports tourism utilized by the South Korean walking trail "Jeju Olle", leading to social change not only domestically but also internationally. Jeju Olle was opened in 2007 and currently it offers 26 courses (totaling 425 km). From 2011 to 2014, over a million Korean walkers rushed to Jeju, causing a walking tour boom. Jeju Olle has changed the leisure-time activities, regional economy, and policies of Korea and it is spreading to Kyushu Olle and Mongol Olle. Ms. Myung-sook Suh, the founder of Jeju Olle, serves as the president of the Jeju Olle Foundation, a non-profit organization (NPO) that operates without dependence on administrational subsidies. The NPO succeeded in transforming an old country road into a fashionable trail decorated with a gentle feminine sensibility that has become known as the "Olle" brand. The NPO’s business operates on revenue from membership fees, company sponsorships, and sales of original brand products and it is supported by a large number of volunteers. Thus, it is a sustainable business model made possible by its financial independence, enthusiastic followers, and brand image, based on female sensibilities and flexibility, and it represents a new global approach to health promotion.
著者
小杉 素子 土屋 智子 谷口 武俊
出版者
The Society for Risk Analysis, Japan
雑誌
日本リスク研究学会誌 (ISSN:09155465)
巻号頁・発行日
vol.21, no.2, pp.115-123, 2011 (Released:2012-01-22)
参考文献数
19
被引用文献数
1

It is important to infer and respect others' values and attitudes for fruitful communication. This paper examines how experts and lay people infer others' risk perception. According to the 2009 questionnaire survey for academic professionals and the general public, professionals estimate that there is a larger difference in risk perception of the technology that they study between themselves and lay people than the general public does. The professionals who hold this feeling perceive the risk of technology as being lower and estimate lay people' s risk perception to be higher. They also focus on positive more than negative aspects of the technology, evaluate its benefits, and tend to presume that negative media coverage greatly affects public perception.
著者
角倉 弘行
出版者
日本臨床麻酔学会
雑誌
日本臨床麻酔学会誌 (ISSN:02854945)
巻号頁・発行日
vol.32, no.7, pp.866-870, 2012 (Released:2013-02-12)
参考文献数
4

無痛分娩を普及させることにより分娩の安全性が向上する理由として,以下の4つが考えられる.無痛分娩を希望する妊婦に対して麻酔科医が分娩前診察を行うことにより,緊急の帝王切開術が必要になった場合でも余裕をもって対処することが可能となる.実際に硬膜外麻酔による無痛分娩を選択した妊婦では,緊急帝王切開の際にも全身麻酔を避けることができる.無痛分娩が普及すれば分娩フロアーに麻酔科医を配置できるようになるので,無痛分娩を選択していない妊婦の分娩の安全性も向上する.さらに無痛分娩が普及して産科麻酔に専従する麻酔科医の数が増えれば,産科麻酔の教育の機会が増えるだけでなく教育の質も向上する.