著者

Teruhisa Uchida Masanori Morise

出版者

ACOUSTICAL SOCIETY OF JAPAN

雑誌

Acoustical Science and Technology (ISSN:13463969)

巻号頁・発行日

vol.42, no.4, pp.214-217, 2021-07-01 (Released:2021-07-01)

参考文献数

10

被引用文献数

1

著者

山口 奈保美 金田 幸司 木本 美由起 末永 裕子 大野 絵梨 内田 英司 福長 直也 柴田 洋孝

出版者

一般社団法人 日本透析医学会

雑誌

日本透析医学会雑誌 (ISSN:13403451)

巻号頁・発行日

vol.54, no.9, pp.465-470, 2021 (Released:2021-09-28)

参考文献数

16

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症例は65歳男性.糖尿病性腎症による末期腎不全に対して腹膜透析を導入した.導入から半年後にESA(erythropoiesis stimulating agent)低反応性貧血を呈するようになり,精査にて胃に生じたangiodysplasiaからの出血を認めた.内視鏡的止血術後,貧血コントロールは改善していたが,加療から8か月後に再度胃のangiodysplasiaからの出血を生じ貧血の進行を認めた.内視鏡的止血術を行い,数日後のフォローアップにて,胃の他部位にangiodysplasiaからの出血を認め再度止血術を要した.それから4か月後に真菌感染が疑われた難治性腹膜炎を発症し血液透析へ移行したところ,以降は消化管出血を起こさずに経過している.末期腎不全患者において,消化管のangiodysplasiaからの出血は療法別では腹膜透析より血液透析症例の割合のほうが多いが,本症例においては腹膜透析から血液透析へ移行したことがangiodysplasiaからの再出血を防ぐことに繋がった可能性がある.

著者

南後 由和 飯田 豊

出版者

日本都市社会学会

雑誌

日本都市社会学会年報 (ISSN:13414585)

巻号頁・発行日

vol.2005, no.23, pp.109-124, 2005-09-05 (Released:2011-02-07)

参考文献数

25

著者

井上 周子 矢澤 省吾 村原 貴史 山内 理香 下濱 俊

出版者

日本神経学会

雑誌

臨床神経学 (ISSN:0009918X)

巻号頁・発行日

vol.55, no.3, pp.151-154, 2015 (Released:2015-03-17)

参考文献数

13

被引用文献数

2 2

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症例は30歳,男性.乳児期に小児科でDravet症候群と診断され,バルプロ酸を主体に加療されたが月に1回以上の全身けいれん発作があり難治に経過した.28歳まで小児科で投薬を受けていたが,てんかん重積状態になったのを契機に神経内科へ紹介されて投薬を引き継いだ.29歳までの1年間にさらに3度の重積となった.患者の母親は処方の変更に消極的であったが,難治であることからくりかえし説明しレベチラセタムを追加投与したところ,全身けいれん発作は1年以上抑止され,本症の成人例にもレベチラセタムの効果を確認できた.また小児科のてんかん患者を引き継ぐ際の問題点も考察した.

著者

坂爪 洋美

出版者

日本労務学会

雑誌

日本労務学会誌 (ISSN:18813828)

巻号頁・発行日

vol.20, no.2, pp.15-20, 2020-06-01 (Released:2020-09-05)

著者

福浦 啓史 青 孝明 佐々木 暢琢 福本 紗与 木村 匡男

出版者

公益社団法人 日本薬学会

雑誌

YAKUGAKU ZASSHI (ISSN:00316903)

巻号頁・発行日

vol.141, no.8, pp.1009-1013, 2021-08-01 (Released:2021-08-01)

参考文献数

11

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The dose of direct oral anticoagulants (DOACs) must be determined based on package insert recommendations. There are reports on the rate of inappropriate DOAC dose usage defined as a dose deviating from the approved dose in the package insert but no reports on factors that led to such deviations. Thus, patients who were admitted to the Suzuka Kaisei Hospital between 1 April 2016 and 31 March 2017 were chosen as subjects. Moreover, the factors that during hospitalization led to dose deviation from the package-insert DOAC dose were retrospectively examined. The characteristics of patients administered doses deviating from the package insert were compared with those of patients in the appropriate-dose group. The finding was that the proportion concomitantly administered antiplatelet agents was higher in the underdose group. In contrast, deviations from the recommended dose did not occur when DOACs were combined with CYP3A4 inhibitors or P-glycoprotein (P-gp) inhibitors. It was suggested that increase in the risk of hemorrhage by antiplatelet agents in combination with oral anticoagulants could explain deviations from the stipulated DOAC dose. In addition, a higher proportion of patients in the overdose group showed depressed Ccr, and gastrointestinal bleeding. In future, it will be necessary to propose principle-based dose changes for patients administered doses deviating from the package insert. If an underdose is administered, it is important to make a dose change that takes the concomitant drugs into consideration.

著者

Thi Thu Thao KHONG Takashi NAKADA Yasuhiko NAKASHIMA

出版者

The Institute of Electronics, Information and Communication Engineers

雑誌

IEICE Transactions on Information and Systems (ISSN:09168532)

巻号頁・発行日

vol.E105.D, no.7, pp.1308-1319, 2022-07-01 (Released:2022-07-01)

参考文献数

38

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We introduce a hybrid Bayesian-convolutional neural network (hyBCNN) for improving the robustness against adversarial attacks and decreasing the computation time in the Bayesian inference phase. Our hyBCNN models are built from a part of BNN and CNN. Based on pre-trained CNNs, we only replace convolutional layers and activation function of the initial stage of CNNs with our Bayesian convolutional (BC) and Bayesian activation (BA) layers as a term of transfer learning. We keep the remainder of CNNs unchanged. We adopt the Bayes without Bayesian Learning (BwoBL) algorithm for hyBCNN networks to execute Bayesian inference towards adversarial robustness. Our proposal outperforms adversarial training and robust activation function, which are currently the outstanding defense methods of CNNs in the resistance to adversarial attacks such as PGD and C&W. Moreover, the proposed architecture with BwoBL can easily integrate into any pre-trained CNN, especially in scaling networks, e.g., ResNet and EfficientNet, with better performance on large-scale datasets. In particular, under l∞ norm PGD attack of pixel perturbation ε=4/255 with 100 iterations on ImageNet, our best hyBCNN EfficientNet reaches 93.92% top-5 accuracy without additional training.

著者

仁昌寺 大輔 比嘉 邦彦

出版者

日本情報経営学会

雑誌

日本情報経営学会誌 (ISSN:18822614)

巻号頁・発行日

vol.41, no.1, pp.65-79, 2021 (Released:2021-10-18)

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Working from home has hardly taken root in Japan. However, emergency declaration against COVID-19 forced many workers to work from home. Several surveys have examined the “productivity” of those workers, but the results have varied. This paper examines and analyzes 567 samples of workers who worked from home during the emergency declaration, and investigation the situation and related factors of “subjective productivity”, which is the self-assessment of productivity of working from home. Age, presence of children, and readiness for working from home were found to be related to subjective productivity. The frequency of working from home after the state of emergency was lifted, as well as desire and possibility, were found to be related to subjective productivity.

著者

平野 実

出版者

日本音声言語医学会

雑誌

音声言語医学 (ISSN:00302813)

巻号頁・発行日

vol.11, no.1, pp.1-11, 1970-04-25 (Released:2010-06-22)

参考文献数

12

被引用文献数

3

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歌声における声区, ピッチ, 強さの調節機構を, 職業的声楽家について研究した.研究には, 喉頭筋筋電図と声帯の高速度映画撮影を用いた.声区は主として声帯筋によって調節される.声区が重い程声帯筋の収縮は強い.側筋と横筋は声区の調節に当たって声帯筋を助ける.したがって, 重い声区では声帯は厚く, 粘膜波動は著明で声門閉鎖期が長く, 開閉速度率が大きい・前筋は声帯筋の拮抗筋として声区に影響を与える.しかし, 第一義的の声区調節者ではない.一般に, 声帯緊張筋および内転筋の活動はピッチの上昇とともに増加する.しかし, 軽い声区の高い音域では, これらの筋のピッチの調節への関与度はより小さい.重い声区の低い音域では, 声の強さは主として内転多によって調節されるが, 軽い声区の高い音域では主として呼吸筋によって調節される.声区, ピッチ, 強さは生きた人間においてはお互いに全く独立した因子ではない.

著者

尾野 裕美

出版者

産業・組織心理学会

雑誌

産業・組織心理学研究 (ISSN:09170391)

巻号頁・発行日

vol.34, no.1, pp.43-58, 2020 (Released:2021-09-09)

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The purpose of this study is to examine the process of promoting male parental leave in enterprises. Semi-structured interviews were conducted for 12 private enterprise promoting male parental leave. The verbal protocols for each participant were analyzed by Modified Grounded Theory Approach (M-GTA). As a result, 59 concepts in 26 categories were created based on the data. The results are summarized as follows: (1)Enterprises that promote male parental leave position work-life balance as a management strategy. (2)Specific measures to promote male parental leave include formulating promotion rules and cultivating culture. (3)As a result of promoting male parental leave, results such as realization of work-life balance and strengthening organizational structure can be obtained.

著者

尾野 裕美

出版者

産業・組織心理学会

雑誌

産業・組織心理学研究 (ISSN:09170391)

巻号頁・発行日

vol.34, no.1, pp.19-30, 2020 (Released:2021-09-09)

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The purpose of this study was to examine whether and how working fathers’ taking parental leave affects career self-reliance and work-family facilitation. I asked 653 married male workers with children under 10 years of age to answer a questionnaire on the internet which consisted of psychological variables of career self-reliance (clarity of career self-image, career development motivation, and career self-responsibility awareness), career self-reliance behavior (adaptation to environmental changes, career development behavior, networking behavior, and proactive job behavior), and work-family facilitation (work-to-family facilitation and family-to-work facilitation). As a result of multiple regression analysis, it was clarified that parental leave promoted clarity of career self-image, career development behavior, adaptation to environmental changes, proactive job behavior, and networking behavior. In addition, it was shown that parental leave promoted work-to-family facilitation.

著者

持田 聖子 岡田 昌毅

出版者

産業・組織心理学会

雑誌

産業・組織心理学研究 (ISSN:09170391)

巻号頁・発行日

vol.34, no.2, pp.147-163, 2021 (Released:2022-04-29)

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The purpose of this study was to examine the process how Japanese mothers working at private companies as a generalist balance their work and family life, and how they adapt their working style after returning from their first maternity leave. Semi-structured interviews were conducted with 20 working mothers who worked at 9 private companies in the Tokyo metropolitan area. The interview data were qualitatively analyzed according to the Modified Grounded Theory Approach (M-GTA). A hypothetical model was constructed with 6 category groups, 23 categories, 1 subcategory, and 81 concepts based on the data. The major findings were as follows. Working mothers face work-family conflict when they return to work from maternity leave, and when they want to develop their careers. In order to manage their work and family tasks, working mothers develop and utilize as many as 40 practical and psychological coping strategies. In the process of doing this, working mothers acquire skills such as multitasking, time management, working in team, etc. When work-family conflict is resolved through these skills, a doublerole lifestyle under restrictive time limitations is normalized for working mothers. Finally, working mothers come to feel work-family enrichment which can be described as “the fruits of the working mother life.” These findings may be used for deeper understandings of the dynamics involved from the perspective of industrial organizational psychology.

著者

増田 智先 山本 由貴

出版者

日本DDS学会

雑誌

Drug Delivery System (ISSN:09135006)

巻号頁・発行日

vol.33, no.5, pp.397-405, 2018-11-25 (Released:2019-02-25)

参考文献数

24

被引用文献数

1

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メサラジン(別名:メサラミン、5-アミノサリチル酸、5-ASA)は、潰瘍性大腸炎とクローン病からなる炎症性腸疾患の第1選択薬として使用される。5-ASAの有効性は、炎症部位への薬物送達の程度によって決定されるが、それは製剤により異なる。近年、特に潰瘍性大腸炎に対する治療薬としてdrug delivery system(DDS)技術を駆使した5-ASA製剤が次々と開発されており、治療効果向上に貢献している。そこで本稿では、それぞれの5-ASA製剤の薬物動態学的特徴に着目し、製剤の有する特徴と臨床的有用性について紹介する。

著者

盛合 秀 折橋 裕二 佐々木 実 沼田 翔伍 浅沼 尚 平田 岳史 淺原 良浩

出版者

一般社団法人日本地球化学会

雑誌

日本地球化学会年会要旨集 2021年度日本地球化学会第68回年会講演要旨集

巻号頁・発行日

pp.168, 2021 (Released:2021-12-15)

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本研究では檜川層の模式地である檜川流域およびその周辺域と西岸域(仏ヶ浦を含む福浦〜牛滝・野平の地域)に分布する珪長質火山岩および火砕岩について地質調査を行い,檜川層層序の再検討を行った.また,新たに縫道石山の石英斑岩についてU-Pb年代測定を行った.野平盆地は地形的に二重の盆状構造を呈しており,負の重力異常分布域(広島ほか,1989)からも示唆されることから,約 4 Maに浅海域で形成された「仏ヶ浦カルデラ」(新称)と約 2 Maに陸域で形成された野平カルデラ(根本・箕浦,1999)が重複していると考えられる.今回新たに得られた縫道石山・石英斑岩のジルコンU-Pb年代は4.7 Maであり,これら石英斑岩は仏ヶ浦カルデラ形成前のリング・ダイクと推定される.

著者

影山 隆之

出版者

日本精神衛生学会

雑誌

こころの健康 (ISSN:09126945)

巻号頁・発行日

vol.13, no.1, pp.34-39, 1998-05-31 (Released:2011-03-02)

参考文献数

10

著者

田村 歩

出版者

日本哲学会

雑誌

哲学 (ISSN:03873358)

巻号頁・発行日

vol.2018, no.69, pp.200-214, 2018-04-01 (Released:2018-08-01)

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Descartes insists, “[...] there is a deceiver of supreme power and cunning who is deliberately and constantly deceiving me. In that case I too undoubtedly exist, if he is deceiving me [...]” (CSM-II, 17; AT-VII, 25). But what is the basis for the insistence that I exist if a deceiver deceives me? At first sight, the Second Meditation seems to say that I exist as an object of the deception, and some earlier studies interpret it as such. Kenny, for example, insists that I exist “as the object of deception, not as the subject of thought.”* On the other hand, however, Wargner insists that I exist “as the active subject whose causal power is being exercised in generating the idea of the demon and all his other ideas.”** The object of this article is to discuss this interpretative problem, examining the earlier studies of Gouhier, Kenny, Pariente, and Wargner. I reject the traditional interpretation (i.e. by Kenny and Pariente) based on the relation between an act and its object, and analyze what is concluded from being deceived, by focusing on the act of deceit itself. Furthermore, the paper shows: 1) it is not my existing but my thinking that is concluded from the supposition that a deceiver is deceiving me; 2) the abilities to understand, affirm, and deny (cf. AT-VII, 28) are discovered in the situation that I am deceived. * Anthony Kenny, Descartes: A Study of His Philosophy (New York: Random House, 1987), 57. ** Stephen I. Wargner, Squaring the Circle in Descartes’ Meditations: The Strong Validation of Reason (Cambridge: Cambridge University Press, 2014), 110-112.

著者

小田 亮

出版者

日本パーソナリティ心理学会

雑誌

パーソナリティ研究 (ISSN:13488406)

巻号頁・発行日

vol.31, no.2, pp.100-101, 2022-09-22 (Released:2022-09-22)

参考文献数

4

被引用文献数

1

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Toyama and Sakurai (2001) reported self-enhancement in the context of agreeableness and conscientiousness among Japanese students, while they observed self-effacement in the context of extraversion and openness. However, their study did not include standardized scales or report the age of the participants. In the present study, self-enhancement and self-effacement in the Big Five personality traits were investigated among a wider age range of participants to conceptually replicate the previous study. In addition to extraversion and openness, self-effacement was newly observed in neuroticism. In contrast to the previous study, there was no self-enhancement in agreeableness and conscientiousness. There were no significant changes in self-enhancement or self-effacement by age group. These results raised doubts about the robustness of the findings of Toyama and Sakurai (2001).

著者

杉田 麟也

出版者

日本口腔・咽頭科学会

雑誌

口腔・咽頭科 (ISSN:09175105)

巻号頁・発行日

vol.23, no.1, pp.23-35, 2010 (Released:2010-09-01)

参考文献数

10

被引用文献数

3

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上咽頭炎は多彩な症状を呈するが診断が難かしい. 従来は上咽頭に触った時の痛みの有無, 出血の有無で診断した. 著者は最初に耳下頸部を触診し圧痛及び硬結感の有無で病変の有無を推測し内視鏡検査, 接触痛, 接触出血の有無により上咽頭炎を診断する事を提案した. 治療は1%塩化亜鉛溶液塗布, ベタメタゾン1.5mg (分2) 4日間が種々の症状軽減に有効である. 咽頭痛が主訴の患者の約90%は責任部位が上咽頭であった. 上咽頭炎検出菌は70%が常在細菌であり, 主な検出菌はインフルエンザ菌, カタル球菌であった.

著者

二宮 和彦

出版者

日本中性子科学会

雑誌

波紋 (ISSN:1349046X)

巻号頁・発行日

vol.25, no.1, pp.13-17, 2015 (Released:2018-11-14)

参考文献数

13

被引用文献数

1 1

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A new non-destructive multi-elemental analysis method using negative muon beam has been developed. This method is based on measurement of characteristic muonic X-rays emitted after muonic atom formation. Muonic X-rays are very hard because of a large mass of the muon, so elemental analysis for deeply inside of a bulk material is possible. In addition, because the muon stopping depth can be controlled by adjusting incident muon energy, three-dimensional analysis will be achieved. To develop this elemental analysis method, we performed muon irradiation experiment for two types of archeological samples; bronze artifacts (coin and mirror) for investigation of quantitative elemental composition and estimation of detection limit, and a gold coin (Tempo-koban) for demonstration of elemental depth-profiling without sample destruction.

著者

平松 隆円 牛田 聡子

出版者

一般社団法人 日本繊維製品消費科学会

雑誌

繊維製品消費科学 (ISSN:00372072)

巻号頁・発行日

vol.45, no.11, pp.837-846, 2004-11-25 (Released:2010-09-30)

参考文献数

8

被引用文献数

1

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大学生の化粧意識構造を解明するために, 大学生378名を対象に質問紙調査を実施した。先行研究を参考に選定した計34項目の化粧意識に関する質問に対する回答を主成分分析した結果, 『魅力向上・気分高揚』『必需品・身だしなみ』『効果不安』の3因子が抽出された.また, これらの因子と化粧行動との関連性を検討した結果, 多くの化粧行動項目との関連性が明らかとなった.