著者

Min-Seok Kim Jae-Joong Kim

出版者

The Japanese Circulation Society

雑誌

Circulation Journal (ISSN:13469843)

巻号頁・発行日

vol.79, no.5, pp.942-947, 2015-04-24 (Released:2015-04-24)

参考文献数

74

被引用文献数

4 33

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Heart failure (HF) is a highly prevalent disorder worldwide and, consequently, a burden on the healthcare systems of many nations. Although the effects of HF are systemic, many therapeutic targets are focused on cardiac dysfunction. The brain is closely related to the heart, but there are few reports on the relationship between these organs. We describe the effects of the brain on HF progression. Specific brain regions control sympathetic drive and neurohumoral factors, which play an important role in disease exacerbation. In addition, we review some of our previous studies on deranged cerebral metabolism and reduced cerebral blood flow during HF. Although the reasons underlying these effects during HF remain uncertain, we propose plausible mechanisms for these phenomena. In addition, the clinical implications of such conditions in terms of predicting prognosis are discussed. Finally, we investigate cognitive impairment in patients with HF. Cognitive impairment through cerebral infarction or hypoperfusion is associated with adverse outcomes, including death. This brief review of brain function during the development of HF should assist with future strategies to better manage patients with this condition. (Circ J 2015; 79: 942–947)

著者

野村 達治

出版者

一般社団法人 映像情報メディア学会

雑誌

テレビジョン (ISSN:18849644)

巻号頁・発行日

vol.19, no.5, pp.316-325, 1965-05-01 (Released:2011-03-14)

著者

田崎 和江 朝田 隆二 渡邊 弘明 白木 康一

出版者

一般社団法人 日本鉱物科学会

雑誌

岩石鉱物科学 (ISSN:1345630X)

巻号頁・発行日

vol.35, no.1, pp.22-33, 2006 (Released:2006-03-01)

参考文献数

27

被引用文献数

1 2

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Characterization of man-made rock-wool fibers were investigated by using optical and electron microscopic techniques and discussed how to affect on human health. The rock-wool fibers were collected from spraying on the roof. Mineralogical analyses were carried out by X-ray powder diffraction. Most fibers can exist as straight or curved fine threads with sharp points μm-nm in diameter under electron microscopy observations. The rock-wool is complex agglomerates of fibers and fumes with cement of calcite. The shape and size are significantly important factors for hazardous assessment of man-made fibers. The fibers are easily adhering to protein-rich spherical materials in 1% BSA (bovine serum albumin) and in ringer’s solution for few days aging. Spherical protein-like materials are similar to “asbestos body” with dumbbells shape. Man-made fibers have been manufactured for over 20 years, but there have been few concerns raised regarding the safety of rock-wool, were considered to be non-hazardous, because of the different durability in the lung. Present study consistently suggests that man-made fibers with fine and sharp points have similar risk as carcinogen of asbestos. The results of both patch test and adhesion materials with dumbbells shape provide clues regarding the mechanisms of tolerance in the lungs of exposed animals, and may be relevant for humans.

著者

久保田 芳太郎

出版者

日本文学協会

雑誌

日本文学 (ISSN:03869903)

巻号頁・発行日

vol.13, no.1, pp.12-13, 1964-01-01 (Released:2017-08-01)

著者

加藤 一郎 岡崎 栄三 中村 紘

出版者

公益社団法人 計測自動制御学会

雑誌

計測と制御 (ISSN:04534662)

巻号頁・発行日

vol.6, no.4, pp.236-241, 1967-04-10 (Released:2009-11-26)

参考文献数

5

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Recently, the artificial hand has been studied and developed for the various purposes. One of them is hand prosthesis. There are many important problems in hand prosthesis. In developing an artificial hand, points to be remarked are the mechanism, the driving method, the driving circuit and the way to make it small and light.Imitating the shape and function of a human hand, we made a prototype model in order to clarify the problems of practical use.First merit of this phototype is having the possibility of operation by two different commands. One command uses a command disk. By turning the disk, the artificial hand repeats the predeturmind sequence of operation. The other command uses the EMG from the human hand.Second merit is in its function. The five fingers and the wrist move independently, so that it can perform complicated actions that are similar those performed by a human hand.Finally, the problems with this prototype model are taken up suggesting the countermeasures and making a prospect of future.

著者

見坂 武彦 片岡 憲司 藤光 隆司 谷 佳津治

出版者

公益社団法人 日本薬学会

雑誌

YAKUGAKU ZASSHI (ISSN:00316903)

巻号頁・発行日

vol.138, no.1, pp.117-122, 2018 (Released:2018-01-01)

参考文献数

21

被引用文献数

5

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Migratory birds are considered as vectors of infectious diseases, owing to their potential for transmitting pathogens over large distances. The populations of barn swallow (Hirundo rustica) migrate from Southeast Asia to the Japanese mainland during spring and migrate back to Southeast Asia during autumn. This migratory population is estimated to comprise approximately hundreds to thousands of individuals per year. However, to date, not much is known about the gastrointestinal microbiota of the barn swallow. In this study, we characterized the fecal bacterial community in barn swallow. Using 16S rRNA gene metagenomic sequencing analysis, we examined the presence and composition of potentially pathogenic bacteria in the fecal samples, which were collected during spring season from Osaka. The number (±S.D.) of total bacteria was approximately 2.1(±3.4)×108 per gram of feces. In most samples, the bacterial community composition was dominated by families, such as Enterobacteriaceae, Pseudomonadaceae, Mycoplasmataceae, Enterococcaceae, Streptococcaceae, and Alcaligenaceae. However, no relationship was found between the bacterial community composition and geographical area in the fecal samples. Potentially pathogenic bacteria were detected at the rate of >0.1%, which included Pseudomonas spp., Escherichia/Shigella spp., Enterobacter spp., Yersinia spp., Mycoplasma spp., Enterococcus spp., Achromobacter spp., and Serratia spp. Our results suggested that barn swallow is instrumental in the transmission of these genera over large distances.

著者

鬼塚 史朗

出版者

日本物理教育学会

雑誌

物理教育 (ISSN:03856992)

巻号頁・発行日

vol.35, no.1, pp.1-4, 1987-03-10 (Released:2017-02-10)

被引用文献数

2

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長さ4m,内径1.7cmの水道用塩ビパイプの一端にイヤホンをとりつけ,パルス状の音を出す.このイヤホンから4cmはなれたところにマイクロホンをつけ,イヤホンから直接くる音とパイプ内を往復して返ってくる音をキャッチする.この直接音と反射音をオッシロスコープの画面に現し,この時間間隔を読みとって,音速値を計算する.パイプのなかには二酸化炭素などの気体を入れて,そのなかでの音速を求めることもできるし,パイプの他端を金属板などで閉じたり開いたりして,固定端や自由端での音の反射の位相変化を観察することもできる.この実験は簡単に実施できるし,結果も良好である.本稿ではその結果を中心にして報告し,高校物理における教卓実験としての教材化について述べる.

著者

梅田 宏明 塙 敏博 庄司 光男 朴 泰祐 重田 育照

出版者

日本コンピュータ化学会

雑誌

Journal of Computer Chemistry, Japan (ISSN:13471767)

巻号頁・発行日

vol.14, no.3, pp.69-70, 2015 (Released:2015-09-25)

参考文献数

6

被引用文献数

5

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GPU acceleration of four-center (4C) inter-fragment Coulomb interaction term (IFC) for OpenFMO, a fragment molecular orbital calculation program, has been implemented and its performance was examined. FMO calculation has two time-consuming steps: Fock matrix construction and IFC calculation, and in our previous letter, it was reported that the former is successfully accelerated with our GPU-enable code. The 4C-IFC calculation is the core part of the latter and its code is similar to that of Fock matrix construction. In this letter, we briefly describe the GPU-accelerated 4C-IFC calculation routine, and report a performance benchmark for GPU-accelerated FMO calculation. The GPU-accelerated program shows 3.3× speedups from CPU only FMO-HF/6-31G (d) calculation for 642 atomic protein on 8 nodes of HA-PACS base cluster.

著者

Toshitake ARAMAKI Takemi ABE Jun YAMASHITA

出版者

The Japanese Society of Agricultural Machinery and Food Engineers

雑誌

JOURNAL of the JAPANESE SOCIETY of AGRICULTURAL MACHINERY (ISSN:02852543)

巻号頁・発行日

vol.44, no.1, pp.45-51, 1982 (Released:2010-04-30)

参考文献数

15

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ピアノ線刃を装着した刈払い作業では, 切込刃装着の場合に比し, 刈刃重量に関係なく, 心拍数及び表面筋電図がともに小さい。この一因として, ピアノ線刃では刈払物が飛散しやすく, 従って刈払い抵抗力が小さいことが考えられる。また, 石なとの障害物に刈刃が当たったときの作業者の精神負担度についても, ピアノ線刃の場合は切込刃に比し小さい。このように, 刈刃の違いによって作業者の受ける生体負担度が相違することを実験的に明らかにした。

著者

Akiko Tanifuji Akira Nozaki Hiroo Makimoto Takeshi Hirano Midori Hirai

出版者

Japanese Society of Drug Informatics

雑誌

Iyakuhin Johogaku (ISSN:13451464)

巻号頁・発行日

vol.19, no.2, pp.82-90, 2017 (Released:2017-09-07)

参考文献数

24

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Objective: We aimed to integrate drug information (DI) documents universally necessary in most hospitals in Japan and share the DI documents nationwide.  For this purpose, we planned to collect details (e.g., types of document, contents, sources of information used for preparing documents) regarding the DI documents prepared by the DI service section of each hospital.Methods: (1) Preliminary research: We searched Ichushi-Web (from January 1977 to December 2015) for cases in which DI documents were prepared by the DI service section of each hospital.  (2) Questionnaire survey: We conducted the survey in DI section of 300 hospitals in Japan that were selected randomly.  We asked the types of DI documents they have, sources of information used for preparing documents, and time needed for preparing documents.Results: (1) Forty titles, including those related to preoperative medication management, simple suspension methods of tablets, and list of dosing with renal impairment, were found.  (2) In total, 148 hospitals (49.3%) responded to the survey.  The main contents were as follows: preoperative medication management (130), the influence of a tube and a filter give to stability of injection medicine (67), list of high-risk medicines (54), suspension or porphyrization information on tablets (37), and others.  The source of information used for preparing these documents was common in several hospitals.Conclusion: It was confirmed that similar DI documents are prepared by several DI sections of hospitals and some sources of drug information are common.

著者

三井田 惇郎

出版者

一般社団法人 日本音響学会

雑誌

日本音響学会誌 (ISSN:03694232)

巻号頁・発行日

vol.29, no.8, pp.445-450, 1973-08-01 (Released:2017-06-02)

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It is important in the acoustical engineering to calculate the amplitude of reflected wave from a target. The calculation method has been developed by J. Saneyoshi, who defined the "sound reflectivity of the target" and derived analytically the approximate formulas of the reflectivity. The reflectivity expresses the ratio of the sound pressure of the reflected wave from the target at the position of the sound source to that of the reflected wave at the same position when the target is replaced by an ideally reflecting infinite normal plane. This formula for a circular plate is given by Eq. (10), which is fairly simple and practical. But as shown in Figs. 7 and 8, the discrepancy increases between the results of its numerical calculations and the actual behavior of the reflected wave when the value of the abscissa R/√λX is increased greatly or the distance between the transducers and a target becomes small in comparison with the size of a target. In this paper, the accurate solution for the reflectivity of the rigid targets of simple shape, such as circular plate and square plate, were derived which is applicable to the above case. As shown in Fig. 1, the velocity of the air particles on the target which is located at a distance r from the sound source is given by Eq. (2); φ_i is the velocity potential of the incident wave and k is the wave length constant. The reflected wave can be considered to be equal to the radiated wave from the target which is vibrating at the velocity of -V_N without incident wave. So, the absolute value of the reflectivity is given by Eqs. (12) and (13). Assuming that the shape of the target is circular, the equations are simplified in the form of Eq. (14). This equation becomes Saneyoshi's relation when √X/λ is increased up to infinity. The numerieal result of these equations are shown in Figs. 2 and 3. Some experiments were executed so as to verify the validity of above theories. These were performed in the air at the frequency of 39. 90 kHz. Fig. 4 shows the arrangement of the apparatus in the experiments. Two piezoelectric transducers were put on the axis of the circular plates were made of hard plastics. The pulse width of the sound wave from the transmitter was 1. 38 ms. The amplitude of the reflected pulse was measured on the screen of the C. R. O. . Figs. 5 and 6 show examples of the results of these experiments. Figs. 7, 8 and 9 show experimental and precise theoretical values of R/√λX divided by the approximate values obtained from Saneyoshi's equation when the reflectivity is minimum. The results of the experiments were in qualitatively reasonable agreement with the numerical results of this precise method.

著者

松原 克志 大辻 永

出版者

一般社団法人 日本科学教育学会

雑誌

日本科学教育学会研究会研究報告 (ISSN:18824684)

巻号頁・発行日

vol.6, no.5, pp.27-28, 1992-04-04 (Released:2017-11-17)

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本研究はSTS教育として科学の本性について構成主義的見地から講義方法を検討したものである. 科学の本性として「科学者杜会で観察事実 (データ) が帰納と演繹によって議論され、科学者杜会内の合意 (共通了解) が形成される. その合意が科学理論であり、科学理論を一般社会では知識と呼ぶ」を講義した後, KJ法の作業を経験させ, 科学の本性のモデルとKJ法のモデルとを提示した. そして演繹と帰納, 集団内の合意という観点から比較した課題作文を書かせた. その結果, 学習者は科学の本性を再定義した上で, 両者を学習者自身の観点から検討していた. このことは構成主義的な見地から科学の本性について学習者が理解していたことを示唆している。

著者

清水 一雄

出版者

日本医科大学医学会

雑誌

日本医科大学医学会雑誌 (ISSN:13498975)

巻号頁・発行日

vol.10, no.2, pp.90-100, 2014 (Released:2014-05-08)

著者

武村 雅之

出版者

公益社団法人 日本地震学会

雑誌

地震 第2輯 (ISSN:00371114)

巻号頁・発行日

vol.58, no.1, pp.41-53, 2005-06-10 (Released:2010-03-11)

参考文献数

32

被引用文献数

1 4

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Three damaging inland earthquakes have occurred in the northern Miyagi Prefecture of the Tohoku District in Japan since 1900. Magnitudes M of the 1962 and the 2003 events were assigned to be 6.5 and 6.4, respectively, from local seismic records observed by the Japan Meteorological Agency (JMA). That of the 1900 event was 7.0, which was determined mainly from the seismic intensity data, while the rank of damage was very lower than other M=7 class inland shallow earthquakes in Japan. In the present study, damage rate data, seismic intensity data, and old seismograms were re-examined to evaluate the magnitude and the location of the focal region of the 1900 event. Re-evaluated magnitude of this event is almost the same as those of the 1962 and 2003 events. The seismic gap between the 1962 and 2003 events is filled with the focal region of the 1900 event obtained. The possibility of a big shallow earthquake occurrence must be very low in near future in the seismic zone of the northern Miyagi Prefecture.

著者

山田 知佳 小林 恵子 関 奈緒

出版者

日本公衆衛生学会

雑誌

日本公衆衛生雑誌 (ISSN:05461766)

巻号頁・発行日

vol.64, no.12, pp.718-726, 2017 (Released:2018-01-05)

参考文献数

21

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目的 問題飲酒の早期発見と適切な介入のための示唆を得るために,交代勤務労働者の飲酒行動の特徴と問題飲酒に関連する要因を明らかにする。方法 A工場の全従業員を対象に無記名自記式質問紙調査を実施した。交代勤務労働者が全員男性であったため,性差を考慮し,日勤者から女性を除外し,230人を分析対象とした。調査内容は問題飲酒の有無,飲酒行動,問題飲酒の関連項目等とし,交代勤務と問題飲酒,交代勤務および問題飲酒と各飲酒行動等の関連について分析を行った。また「問題飲酒の有無」を従属変数とし,単変量解析でP<0.20の変数を独立変数として,年齢を強制投入した上で,変数減少法による二項ロジスティック回帰分析を行った。結果 交代勤務労働者の飲酒行動の特徴として,「自宅」での飲酒が日勤者に比べ有意に多かった(P=0.037)。交代勤務労働者の飲酒理由は日勤者に比べ「よく眠れるように」(P=0.006)が有意に多く,入眠のために飲酒することがある交代勤務労働者が,日勤者に比べ有意に多かった(P<0.001)。 「入眠のための飲酒あり」(OR 6.38, 95%CI:2.11-19.29, P=0.001),「(職業性ストレスの)身体的負担が高いこと」(OR 2.24, 95%CI:1.11-4.51, P=0.024)は問題飲酒のリスク増加と有意に関連が認められ,「家族・友人からのサポートが高いこと」は問題飲酒のリスク減少と有意な関連が認められた(OR 0.75, 95%CI:0.58-0.97, P=0.030)。結論 男性交代勤務労働者の飲酒行動の特徴と問題飲酒の関連要因について検討した結果,日勤者に比べ「自宅での飲酒」,「入眠のための飲酒」が有意に多いことが特徴であった。 男性交代勤務労働者の問題飲酒のリスク増加には,「入眠のための飲酒あり」,「身体的負担が高い」ことが関連し,「家族・友人からのサポート」は問題飲酒のリスク減少に関連していたことから,夜間の勤務終了後の入眠困難感を把握し,飲酒以外の対処行動を支援するとともに,友人や家族からのサポートの重要性について啓発が必要である。

著者

Michiko EGO Chuichi TSUTSUMI Taro NAGAHARA

出版者

The Japan Society of Home Economics

雑誌

Journal of Home Economics of Japan (ISSN:04499069)

巻号頁・発行日

vol.27, no.7, pp.511-514, 1976-10-20 (Released:2010-03-10)

参考文献数

9

被引用文献数

1

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1) キャベツをせん切り水浸することにより, P, Na, K, Mgなどは約10%が失われ, Caは溶出しにくいことが認められた. また水浸5分で溶出すべき無機成分の大部分が溶出した.2) ほうれん草はゆでることにより脱イオン水ゆで, 水道水ゆでにおいてCaの溶出率がそれぞれ14%と 8%と最も溶出されにくく, 一方Kはどちらでゆでてもほぼ60%という大きな溶出を示した. Fe, P, Mg, Cu, Zn などの溶出はほぼ中間に位置した.キャベツは脱イオン水あるいは水道水で4分ゆでたとき, 水道水ゆでは全体に溶出率が低いが, Fe, Caが溶出しにくく, P, Mgなどはほぼ30%溶出した. Kはいずれでゆでても30~40%が溶出した. 30分ゆでた場合は, 4分ゆでに比べ溶出率が大となり, とくにKは約 70%が溶出した. 大切りゆでと短冊切りによる溶出率の差は, ほとんど認められなかった.

著者

Michiko EGO Chuichi TSUTSUMI Taro NAGAHARA

出版者

The Japan Society of Home Economics

雑誌

Journal of Home Economics of Japan (ISSN:04499069)

巻号頁・発行日

vol.26, no.7, pp.540-543, 1975-10-20 (Released:2010-03-10)

参考文献数

7

被引用文献数

1

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1) パセリの無機成分のうち, Fe, Cu, Znは, 水洗時に40~ 50%流出し, ついで水洗い試料をみじん切り水浸したのちもほぼ同様の流出が認められ, このことは付着物の脱着によるのではないかと推論された.2) パセリをみじん切り水浸したさい, P, Ca, Na, Mgなどは溶出しにくいことが認められた. 水道水処理した場合は脱イオン水処理に比べて, Ca, Na, Mg, Znなどの残存量がやや多いことが認められた. Kはいずれにおいても約20%失われた. また水浸5分で溶出すべき無機成分の大部分が溶出した.

著者

今井 一良

出版者

日本英学史学会

雑誌

英学史研究 (ISSN:03869490)

巻号頁・発行日

vol.1990, no.22, pp.1-14, 1989 (Released:2010-01-25)

参考文献数

7

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In 1888 Kyoka Izumi (born Kyotaro Izumi in 1873), who failed in the entrance examination of the Fourth Higher Middle School at Kanazawa, entered a private school kept by Tajiro Inami, and was soon left in charge of English lessons there, since he had attended a missonary school (the Hokuriku Eiwa Gakko) before and was very good at English.Tajiro Inami was also known as a compiler of an English-Japanese dictionary entitled 'the Shinsen Eiwa Jiten'. This dictionary was published in 1886 from the Unkondo's which had already issued a literary magazine, 'the kinjo Shishi'.Therefore, the advertisements of sale of Inami's dictionary were put in this magazine many times, and in addition so much information concerning English learning at Kanazawa or in Tokyo was reported.In this essay, I would like to give a full detail of the following items, amplifying the above-mentioned matter : 1. Biographical Sketch of Tajiro Inami.2. On 'the Kinjo Shinshi '.3. On 'the Shinsen Eiwa Jiten'.4. Situation of English learning at Kanazawa about the middle of 1880's based on the reports in the Kinjo Shinshi.

出版者

公益社団法人 精密工学会

雑誌

精密工学会誌 (ISSN:09120289)

巻号頁・発行日

vol.84, no.1, pp.46-51, 2018-01-05 (Released:2018-01-05)

参考文献数

4

出版者

THE FUKUSHIMA SOCIETY OF MEDICAL SCIENCE

雑誌

FUKUSHIMA JOURNAL OF MEDICAL SCIENCE (ISSN:00162590)

巻号頁・発行日

vol.63, no.2, pp.126-126, 2017 (Released:2017-08-09)

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The below article has been retracted. Article title 「EFFECTS OF OLPRINONE ON NEUROMUSCULAR BLOCKADE CAUSED BY VECURONIUM」Author Takaaki Katayama , Yuhji Saitoh , Chiaki Nemoto , Takahiro Hirama , Tsuyoshi Isosu , Masahiro Murakawa Journal title FUKUSHIMA JOURNAL OF MEDICAL SCIENCE Vol.53, No.2 2007:61-69 Fukushima Medical SocietyEditorial CommitteeJuly 5 , 2017