著者

赤羽 恵一 飯本 武志 伊知地 猛 岩井 敏 大口 裕之 大野 和子 川浦 稚代 立崎 英夫 辻村 憲雄 浜田 信行 藤通 有希 堀田 豊 山崎 直 横山 須美

出版者

日本保健物理学会

雑誌

保健物理 (ISSN:03676110)

巻号頁・発行日

vol.49, no.3, pp.145-152, 2014 (Released:2015-07-18)

参考文献数

52

被引用文献数

4 7

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In April 2011, the International Commission on Radiological Protection (ICRP) issued the statement on tissue reactions. This stimulated interest in many countries. The Expert Committee on Radiation Protection of the Lens of the Eye was established in the Japanese Health Physics Society, and in April 2013, started discussion about the international developments and recent studies related to the dosimetry of the lens of the eye. This committee now publishes the interim report consisting of parts I-VI. Of these, this Part I overviews the structure of the eye and lens, cataract types and the scientific evidence of its new dose threshold and equivalent dose limit newly recommended by the ICRP.

著者

赤羽 恵一 飯本 武志 伊知地 猛 岩井 敏 大口 裕之 大野 和子 川浦 稚代 立崎 英夫 辻村 憲雄 浜田 信行 藤通 有希 堀田 豊 山崎 直 横山 須美

出版者

日本保健物理学会

雑誌

保健物理 (ISSN:03676110)

巻号頁・発行日

vol.49, no.4, pp.171-179, 2014 (Released:2015-12-18)

参考文献数

21

被引用文献数

3

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Many studies have been internationally reported as part of projects regarding the radiation exposure for the lens of the eye of medical staff members under various conditions, methods of dosimetry and development of dosimeters for the lens of the eye. Recently conducted studies include the Retrospective Evaluation of Lens Injuries and Dose (RELID) of the International Atomic Energy Agency, Occupational Cataracts and Lens Opacities in interventional Cardiology (O’CLOC) study in France, Optimization of Radiation Protection of Medical Staff (ORAMED) project in European countries, and a 20-year prospective cohort study among US radiologic technologists. Given the newly implemented dose limit for the lens of the eye by the International Commission on Radiological Protection (ICRP), we summarized these studies as the necessary information for reconsideration of the Japanese dose limit for the lens of the eye. In addition, this article also covers the exposures for the lens of the eye of clean-up workers in the Chernobyl accident as shown in ICRP Publication 118 and the results of a hearing survey with specialists of the Academy of Medical Science of Ukraine.

著者

高山 慈子 三浦 英司 細井 紀雄 前田 伸子 渋谷 耕司 石川 正夫

出版者

社団法人 日本補綴歯科学会

雑誌

日本補綴歯科学会雑誌 (ISSN:03895386)

巻号頁・発行日

vol.44, no.2, pp.208-220, 2000-04-10 (Released:2010-08-10)

参考文献数

23

被引用文献数

2 1

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This study was conducted to investigate the principal factors involved in the discoloration of 12 Wt% Au-Ag-Pt alloy. Luminance of cast clasps, oral conditions, the presence cariogenic microbes such as Streptococcus mutans and Lactobacillus in saliva, Candida on the tongue and the amount of volatile sulfur compounds (VSC: H2S and CH3SH) produced by the tongue coating were evaluated in 70 subjects (VSC: 45 subjects). The surfaces of cast clasps were observed using an electron probe X-ray microanalyzer and changes in the surface were evaluated in relation to the degree of discoloration.The results were as follows:1. The Mann-Whitney U-test revealed statistically significant differences (p<0.05) between the production of CH3SH and VSC (CH3SH+H2S) and luminance.2. Examinations of the cross section of markedly discolored casts revealed a very rough surface. A distinct peak of S was also indicated by linear analysis.The results demonstrated that among the many different factors such as oral conditions and oral flora, the production of CH3SH was the most significantly related to the discoloration of 12 Wt% Au-Ag-Pt alloy. The potential for discoloration tended to be higher in subjects who had a high production of CH3SH.

著者

仙石 潜

出版者

耳鼻咽喉科展望会

雑誌

耳鼻咽喉科展望 (ISSN:03869687)

巻号頁・発行日

vol.30, no.2, pp.247-251, 1987-04-15 (Released:2011-08-10)

著者

Kenji Hagita Kenji Mori

出版者

Eastern Asia Society for Transportation Studies

雑誌

Journal of the Eastern Asia Society for Transportation Studies (ISSN:18811124)

巻号頁・発行日

vol.11, pp.1999-2014, 2015 (Released:2015-12-26)

参考文献数

12

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Traffic accidents shortly before and after sunset in Chiba were analyzed. The rate of traffic accidents shortly after sunset was found to be higher than at any other time, whereas the rate shortly before sunset was found to be lower. Traffic accidents caused by sun glare tended not to occur shortly before sunset, because the presence of topographic features meant that the sun had already effectively set. The rate of pedestrian accidents shortly after sunset was higher than that of any other time; the rate shortly before sunset was slightly lower than in day and shortly after sunset, because it was not dark and drivers were not dazzled by sun glare before sunset. However, it is already the case that many vehicle headlights are on shortly after sunset, so it is difficult to decrease pedestrian accidents only by advising drivers to use their lights in the hour before sunset.

著者

長島 雄毅

出版者

人文地理学会

雑誌

人文地理学会大会 研究発表要旨 2012年 人文地理学会大会

巻号頁・発行日

pp.34-35, 2012 (Released:2013-12-17)

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本報告は、近世京都商家が雇用する奉公人の性格を、奉公人請状を使用して、性別・出身地・身分などの点から検討していくものである。

著者

田中 利幸

出版者

日本神経回路学会

雑誌

日本神経回路学会誌 (ISSN:1340766X)

巻号頁・発行日

vol.15, no.2, pp.126-135, 2008-06-05 (Released:2008-11-28)

参考文献数

26

被引用文献数

1

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難しい組み合わせ最適化問題に対して,個々の問題の代わりにランダムな問題群を考え,問題の規模を十分大きくすることによって問題の詳細によらない巨視的な構造を捉えよう,という情報統計力学の方法論が注目を集めている.本稿では,kSATに対する近年の情報統計力学的アプローチの概要を解説するとともに,線形符号の復号の問題を一種の組み合わせ最適化問題として捉え,kSATとの対比に留意しつつ情報統計力学からのアプローチの一端を紹介する.

著者

Daisuke NISHIO-HAMANE Yukikazu OGOSHI Tetsuo MINAKAWA

出版者

一般社団法人日本鉱物科学会

雑誌

Journal of Mineralogical and Petrological Sciences (ISSN:13456296)

巻号頁・発行日

vol.107, no.3, pp.121-126, 2012 (Released:2012-07-12)

参考文献数

12

被引用文献数

3 2

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Miyahisaite, (Sr,Ca)2Ba3(PO4)3F, a new mineral of the hedyphane group in the apatite supergroup, is found in the Shimoharai mine, Oita Prefecture, Japan. Miyahisaite is colorless and occurs as a pseudomorphic aggregate (up to about 100 μm in size) along with fluorapatite in the quartz matrix in a namansilite-rich layer of the chert. Its hardness is 5 on the Mohs scale, and its calculated density is 4.511 g/cm3. The empirical formula of miyahisaite is (Sr1.366Ca0.717)Σ2.083Ba2.911P3.002O12(F0.898OH0.088Cl0.014)Σ1.00, which is representatively shown as (Sr,Ca)2Ba3(PO4)3F. Its simplified ideal formula is written as Sr2Ba3(PO4)3F, which requires 23.25 wt% SrO, 51.62 wt% BaO, 23.89 wt% P2O5, 2.13 wt% F, and -0.90 wt% F = O, for a total of 100.00 wt%. The mineral is hexagonal with a space group P63/m, unit cell parameters a = 9.921 (2) Å, c = 7.469 (3) Å, and V = 636.7 (3) Å3, and Z = 2. The eight strongest lines in the powder XRD pattern [d (Å), (I/I0), hkl] are 3.427 (16) 102, 3.248 (22) 120, 2.981 (100) 121, 2.865 (21) 300, 1.976 (23) 123, 1.874 (16) 140, 1.870 (15) 004, and 1.864 (17) 402. The mineral was formed by the reaction between fluorapatite and the Ba-bearing fluid that produced the aegirine-rich layer with hydrous Ba-rich minerals during the late-stage activity.

著者

Mark W. Greenlee

出版者

日本基礎心理学会

雑誌

基礎心理学研究 (ISSN:02877651)

巻号頁・発行日

vol.35, no.1, pp.54-58, 2016-09-30 (Released:2016-10-25)

参考文献数

39

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Since the advent of functional magnetic resonance imaging cognitive science has experienced a turn towards neuroscience. Models of perceptual and cognitive functions can now be tested against patterns of human brain activity in anatomically well-defined regions of interest. Structural and functional connectivity analyses can inform us about how different brain regions are interconnected and interact in perceptual and cognitive tasks, as well as during resting states. In this study I review the results of a series of experiments that aimed to reveal the visual-vestibular sensory processing underlying self-motion perception. We (Frank, Baumann, Mattingley, & Greenlee, 2014; Frank, Wirth, & Greenlee, 2016) localized regions in the posterior insula using fMRI with visual and vestibular stimuli. The results suggest that two areas in this part of the brain are involved in self-motion perception: the parieto-insular vestibular cortex (PIVC) for the processing of vestibular information and posterior insular cortex (PIC) for the integration of visual and vestibular information. The results suggest that these two regions play different roles in the integration of visual and vestibular cues related to self-motion perception.

著者

尾股 定夫 春田 峰雪

出版者

公益社団法人 日本生体医工学会

雑誌

生体医工学 (ISSN:1347443X)

巻号頁・発行日

vol.52, no.Supplement, pp.OS-62-OS-63, 2014 (Released:2014-10-04)

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We developed a new cuff-less blood pressure measuring instrument using our phase shift technology. Using the new device we can continuously and noninvasively get information on the blood pressure per pulsation of the blood vessel. However the traditional medical device used in hospital or in our house is not able to measure continuously the blood pressure. Over the past many years, there have been numerous studies on cuff less blood pressure monitor, but a new medical device capable of detecting invasively blood pressure have not been developed. This study describes development of a new type of cuff-less blood pressure instrument which is designed to operate with an optical sensor.

著者

利谷 信義 森 實

出版者

日本法社会学会/有斐閣

雑誌

法社会学 (ISSN:04376161)

巻号頁・発行日

vol.1966, no.18, pp.140-210, 1966-04-20 (Released:2009-04-03)

参考文献数

17

著者

Keita Shibata Arisa Matsumoto Ayumi Nakagawa Keiko Akagawa Akihiro Nakamura Toshinori Yamamoto Naomi Kurata

出版者

公益社団法人日本薬学会

雑誌

Biological and Pharmaceutical Bulletin (ISSN:09186158)

巻号頁・発行日

vol.39, no.11, pp.1767-1773, 2016-11-01 (Released:2016-11-01)

参考文献数

19

被引用文献数

7

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Community pharmacies in Japan have long been advocated as effective sources of nonprescription medicines and health-related advice. Consumers sometimes self-treat symptoms of minor illnesses without consulting a pharmacist because the benefits of such consultations are not adequately recognized. The aim of this study was to investigate the use and impact of pharmacist consultations before purchase of nonprescription laxatives. An online survey was conducted July 14–22, 2012 with 500 respondents (250 men, 250 women), ranging 20–60 years old. All participants had purchased nonprescription laxatives for constipation within the past year. Stratified analysis was used to compare responses in groups that had and had not consulted a pharmacist before purchase. Consulting a pharmacist appears to improve consumers’ awareness and makes them more likely to use appropriate medication. Those who consulted a pharmacist were better able to identify side effects and take appropriate action than the group that did not consult the pharmacist. Those who consulted a pharmacist were also significantly more likely to say that they would consult a pharmacist in the future. These results indicate that it is important for consumers to be able to consult with pharmacists, to improve consumers’ awareness of side effects and to self-medicate appropriately, and hence improve their quality of life. Pharmacists in community pharmacy could be more active in health promotion campaigns, such as drug safety, campaigns, to raise their public profile. Increased public awareness of what pharmacists in community pharmacy do will make it easier for patients to consult with them.

著者

中島 秀之

出版者

特定非営利活動法人 横断型基幹科学技術研究団体連合

雑誌

横幹 (ISSN:18817610)

巻号頁・発行日

vol.3, no.2, pp.85-86, 2009 (Released:2016-03-23)

著者

Sho Yamamoto Tetsuri Kikuchi Yutaka Yamagiwa Takashi Handa

出版者

一般社団法人 園芸学会

雑誌

The Horticulture Journal (ISSN:21890102)

巻号頁・発行日

pp.OKD-006, (Released:2016-11-03)

被引用文献数

5

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Lilium auratum var. auratum Lindl. is distributed in the eastern part of Honshu, the main island of Japan. L. auratum var. platyphyllum Baker is endemic to the Izu archipelago, which consists of nine large islands located in south of Honshu’s Izu peninsula. Both varieties have been used as important parents of Oriental hybrid lily cultivars. They have large white flowers with yellow central stripes and colored spots on their tepals. L. auratum var. platyphyllum has larger flowers and wider leaves than L. auratum var. auratum. L. auratum var. platyphyllum has yellow spots, whereas L. auratum var. auratum has red or brown ones. Natural hybridization between these two taxa has been suggested on the basis of spot colors of populations in the Izu archipelago and the Izu peninsula. However, their genetic diversity and hybridity in nature have not been reported. We performed morphological analysis using 72 individuals of L. auratum var. auratum from seven populations and 72 individuals of L. auratum var. platyphyllum from six populations. We also performed simple sequence repeat (SSR) analysis using 102 individuals of L. auratum var. auratum from seven populations and 134 individuals of L. auratum var. platyphyllum from six populations. Both analyses revealed that L. auratum var. auratum and L. auratum var. platyphyllum are genetically different and that L. auratum var. platyphyllum has genetic diversity among populations in the archipelago.

著者

藤井 敏弘 村井 慎哉

出版者

公益社団法人 高分子学会

雑誌

高分子論文集 (ISSN:03862186)

巻号頁・発行日

vol.62, no.5, pp.201-207, 2005-05-25 (Released:2010-03-15)

参考文献数

20

被引用文献数

1 3

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毛髪および羊毛からのタンパク質抽出に有効な信大法をヒト爪に適用した. この結果, 従来法と比べ, 信大法を用いた場合の抽出タンパク質量は約2.5倍多かった. また, 毛髪, 羊毛と比べ, 抽出標品は, ハードケラチンやマトリヅクスタンパク質に加え, 爪の特性であるソフトケラチンを含んでいた. 爪ケラチンおよびマトリックスタンパク質にリン酸化分子種が含まれていることから, 翻訳後の修飾が強く示唆された. 毛髪タンパク質溶液からフィルムヘ簡便に変換するブレキャスト法, ポストキャスト法, ソフトポストキャスト法を爪タンパク質に適用したところ, すべての方法でフィルム形成が見られ, 70~90%の高い割合で回収された. フィルムはハードケラチンを主成分とし, ソフトケラチン, マトリックスタンパク質を含んでいた. タンパク質溶液からフィルムヘ1分以内の短時間で形成されるプレキャスト法およびポストキャスト法で得られたフィルムは白色で不透明性であったが, 一方, 形成に5~40分ぐらい必要なポストキャスト法 (pH5) とソフトーポストキャスト法で得られたフィルムは半透明性を示した. SEM観察から, 半透明性のフィルムは不透明のフィルムよりもその表面が滑らかであった. これら半透明性のフィルムは, 270~295nmに吸収をもつことから, 新規のUVケア機能をもつ製品へ期待される.

著者

Hiroyuki IWASAKI

出版者

(公社)日本気象学会

雑誌

気象集誌. 第2輯 (ISSN:00261165)

巻号頁・発行日

vol.94, no.5, pp.431-442, 2016 (Released:2016-10-31)

参考文献数

25

被引用文献数

7

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Lightning features over the Tibetan Plateau were studied in relation to topography using the World Wide Lightning Location Network (WWLLN) dataset obtained from April 2009 until December 2014. To describe the strength of lightning strokes, lightning strokes with energies above the 90th percentile (7666 J) were defined as strong lightning (S-lightning) strokes, and the ratio of S-lightning strokes to the overall number of lightning (O-lightning) strokes was defined as the strong ratio (S-ratio). O-lightning density over the Tibetan Plateau was found to be high in general, except over the western part of analysis region. Minimum-density zones were observed along the Himalayas approximately 6 km above sea level and in deep valleys within the Tibetan Plateau. The maximum- and minimum-density zones also exhibited maximum and minimum annual rainfall amounts, respectively. S-lightning strokes were also found to frequently occur over the Tibetan Plateau, and most S-ratios in the analysis units exceeded 30 %, which corresponds to three times the global mean. In particular, the S-ratios over the southern part of the Tibetan Plateau, including the Himalayas, were found to be high (50 %) and to correspond with the zone that had the minimum O-lightning density. The maximum O-lightning density was observed to occur during the summer at an elevation approximately 0.2-1.0 km higher than the plateau level. The O-lightning and S-lightning densities around the Nagqu sonde station were negatively correlated with the Showalter stability index (SSI) and the vertical wind shear. The S-ratio and average stroke energy were found to be negatively correlated with the vertical shear but not with the SSI.

著者

森実 飛鳥 高橋 淳

出版者

公益社団法人 日本薬理学会

雑誌

日本薬理学雑誌 (ISSN:00155691)

巻号頁・発行日

vol.147, no.5, pp.264-268, 2016 (Released:2016-05-13)

参考文献数

27

被引用文献数

1

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パーキンソン病の治療としてはL-dopaをはじめとした薬剤による内服治療が標準的である.薬剤治療は初期には有効であるが,4~5年を経過すると薬の有効性が減じ,ジスキネジアやon-off現象などの副作用が出現し,薬剤のみでの疾患コントロールが困難になってくる.補助的な治療の一つとして中絶胎児組織を使った中脳細胞移植治療が欧米で試験的に行われてきた.この胎児移植では一定の効果はあるものの,ドナー細胞の供給が難しく,そのために質の安定性が保たれないことなどから一般的な治療とはなっていない.この問題点を解決すべく,人工多能性幹細胞(iPS細胞)の応用が期待されている.我々はiPS細胞からドパミン神経前駆細胞を分化誘導し,パーキンソン病に対する細胞移植治療を目指して研究を行ってきた.すでに臨床応用可能な分化誘導のプロトコールを確立し,パーキンソン病モデル動物等を用いて前臨床試験を行っている.移植した細胞は脳内に生着し,モデル動物の機能回復に寄与することを確認している.iPS細胞利用の1つのアドバンテージとして自家移植の可能性が挙げられる.自家移植は拒絶反応が最小限に抑えられて理想的ではあるが,コストや時間の問題から臨床現場で普及するにはハードルが高い.次善の策として,健常者の細胞から臨床グレードで樹立された既存のiPS細胞を用いる方法が考えられる.京都大学で始まったiPS細胞ストックプロジェクトではヒト白血球型抗原(HLA)がホモ接合体である健常人ドナーの細胞から樹立したHLAホモiPS細胞を備蓄していき,各患者の種々な型のHLAと適合し易いiPS細胞を集めている.これが整備されると将来的には様々な領域でHLA適合移植が可能となる.我々はこのストックiPS細胞を利用し,パーキンソン病に対し他家(同種)移植を行う臨床治験を計画している.

著者

角嶋 直美 矢作 直久 藤城 光弘 井口 幹崇 岡 政志 小林 克也 橋本 拓平 小俣 政男

出版者

一般社団法人 日本消化器内視鏡学会

雑誌

日本消化器内視鏡学会雑誌 (ISSN:03871207)

巻号頁・発行日

vol.47, no.6, pp.1266-1271, 2005-06-20 (Released:2011-05-09)

参考文献数

12

被引用文献数

1

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【背景と目的】内視鏡的粘膜下層剥離術(ESD)の登場により,従来では考えられなかった大型病変も内視鏡的に治療されるようになってきた.しかし,ESDによって生じた大型人工潰瘍の治癒過程についての詳細は明らでかはない.そこで,ESD後の治癒過程を明らかにするため,経時的な内視鏡像の検討を行った.【方法】当科においてESDによって治療された胃粘膜内腫瘍70症例を対象として,ESD後潰瘍の治癒過程および瘢痕形態を,切除サイズ,部位,胃壁の断面区分別に検討した.内視鏡観察は,原則としてESD後1,4,8,12週目に行い,抗潰瘍治療として,プロトンポンプ阻害薬(PPI)及びスクラルファート通常量を投与した.【結果】ESDの切除サイズは平均34.7mm(20.0~90.0mm)であった.ESD後潰瘍は切除サイズや部位・周在によらず,全例において8週までにS1-2stageに治癒・瘢痕化した.【結論】ESD後潰瘍は大型のものでも,消化性潰瘍と同様の治療で術後8週以内に治癒・瘢痕化する.これらは,ESD後のフォローアップや治療計画の立案に非常に有用な知見と考えられた.

著者

水谷 后宏 井上 武 間野 暢 明石 修 松浦 知史 藤川 和利

出版者

日本ソフトウェア科学会

雑誌

コンピュータ ソフトウェア (ISSN:02896540)

巻号頁・発行日

vol.32, no.3, pp.3_101-3_110, 2015-07-24 (Released:2015-09-04)

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Structured overlay networks that support range queries cannot hash data IDs for load balancing, in order to preserve the total order on the IDs. Since data and queries are not equally distributed on the ID-space without hashing in range-based overlay networks, uneven loads are imposed on the overlay nodes. Existing load balancing techniques for range-based overlay networks distribute the loads by using data reallocation or node migration, which makes the networks very unstable due to heavy data reallocation or frequent churn.This paper proposes a novel scheme that distributes, fairly, the loads without node migration and with little data reallocation, by sharing some ID-space regions between neighboring nodes. Our “overlapping” ID-space management scheme derives the optimal overlap based on kernel density estimations; the query loads based on the statistical theory are used to calculate the best overlap regions. This calculation is executed in a distributed manner with no central coordinator. We conduct thorough computer simulations, and show that our scheme alleviates the worst node load by 20–90 % against existing techniques without node migration and with least data reallocation.

著者

石原 忠 紀成 尚志 保田 正人

出版者

公益社団法人 日本水産学会

雑誌

日本水産学会誌 (ISSN:00215392)

巻号頁・発行日

vol.40, no.3, pp.309-316, 1974-03-25 (Released:2008-02-29)

参考文献数

17

被引用文献数

2 2

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The presence of high thiaminase activity in anchovy was reported in the previous paper. It was suggested from the report that continuous feeding of animals with the anchovy may possibly result in vitamin B1 deficiency.In the present experiments, male chickens were fed with a diet containing water extract of anchovy and the effects on growth were studied. For the control, this water extract was boiled for 10 min before feeding.As a result of feeding with the non-boiled extract of anchovy, the amount of B1 in liver and muscle gradually decreased but the amount of pyruvic acid in blood increased. Anorexia and retardation of growth were also observed, and heart rate, respiratory rate and body temperature gradually decreased, resulting finally in typical vitamin B1 deficiency.When 0.5 or 1.0 mg of vitamin B1 was injected daily into the leg muscle of B1 deficient male chickens, they regained their stamina in one or two days.The control group given boiled extract showed favorable growth without any abnormal symptoms.