著者

吉田 隆志 波多野 力 伊東 秀之

出版者

社団法人 有機合成化学協会

雑誌

有機合成化学協会誌 (ISSN:00379980)

巻号頁・発行日

vol.62, no.5, pp.500-507, 2004-05-01 (Released:2009-11-13)

参考文献数

24

被引用文献数

5 14

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Large-size secondary metabolites with dimeric-oligomeric and/or dendrine-type structure from higher plants are regarded as natural nanomolecules which are constructed in a bottom-up pathway from small molecules under biological condition. Among them are polyphenols classified as tannins which have large molecular weights ranging from 500 to 4000, and strong affinity to proteins, alkaloids and heavy metals to form complex molecules (precipitates). They constitute two major groups : one is condensed tannins (proantocyanidins), which are composed of flavan-3-ol units linked through C-C bond, and the other is hydrolyzable tannins, which are principally multiple esters of D-glucose with gallic acid and its oxidative metabolites. This paper reviews the diverse structural characteristics of both tannins, especially ellagitannin oligomers up to pentamers, and examples of their biological activities. Formation of insoluble and soluble complex between tannins and proteins are also described.

著者

芦田 淳

出版者

公益社団法人 日本農芸化学会

雑誌

日本農芸化学会誌 (ISSN:00021407)

巻号頁・発行日

vol.18, no.8, pp.723-726, 1942 (Released:2008-11-21)

参考文献数

17

被引用文献数

1 2

著者

Yuji Yamada Yoshitaka Miyakawa Mitsuaki Sawano Yutaka Okano

出版者

一般社団法人 日本内科学会

雑誌

Internal Medicine (ISSN:09182918)

巻号頁・発行日

vol.53, no.10, pp.1083-1085, 2014 (Released:2014-05-15)

参考文献数

15

被引用文献数

2 10

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Acquired coagulation factor deficiency is a rare disorder that occurs in patients with drug reactions, malignancy and collagen diseases as well as during pregnancy. Most cases are caused by factor VIII inhibitors. We herein describe the case of a 61-year-old Japanese man with acquired factor V inhibitor who developed symptoms 11 days after lung surgery for empyema. The patient required mechanical ventilation to treat acute respiratory failure due to severe pulmonary hemorrhage. He responded poorly to steroid pulse therapy; however, treatment with rituximab was successful.

著者

Giuseppe Grosso Stefano Marventano Fabio Galvano Andrzej Pajak Antonio Mistretta

出版者

日本疫学会

雑誌

Journal of Epidemiology (ISSN:09175040)

巻号頁・発行日

pp.JE20130166, (Released:2014-05-03)

参考文献数

32

被引用文献数

22 61

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Background: Intake of caffeinated beverages, such as coffee and tea, has been related to improvements in components of metabolic syndrome (MetS), but studies conducted in the Mediterranean region are scarce. The aim of this study was to evaluate whether or not consumption of a variety of beverages containing caffeine was associated with components of MetS in an Italian population.Methods: From May 2009 to December 2010, a cross-sectional survey was conducted on 1889 inhabitants living in Sicily, southern Italy. Data regarding demographic characteristics, habitual beverage intake, and adherence to the Mediterranean diet were collected, and clinical information was retrieved from the general practitioners’ computer records.Results: After adjusting for all covariates, coffee (odds ratio [OR] 0.43, 95% confidence interval [CI] 0.27–0.70) and tea (OR 0.51, 95% CI 0.34–0.78) were associated with MetS, whereas no association was observed between caffeine intake and MetS. Among other factors, age, body mass index, physical activity, current smoking, and adherence to Mediterranean diet were associated with having MetS. Triglycerides were inversely associated with consumption of both espresso coffee and tea. The healthy effects of such beverages were more evident in individuals with unhealthy dietary habits.Conclusions: Although no direct association between caffeine intake and MetS or its components was observed, coffee and tea consumption was significantly related to reduced odds of MetS.

著者

林 直行 松藤 康司

出版者

一般社団法人 廃棄物資源循環学会

雑誌

廃棄物資源循環学会論文誌 (ISSN:18835856)

巻号頁・発行日

vol.22, no.1, pp.1-9, 2011 (Released:2011-03-24)

参考文献数

7

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循環型社会の構築へ向けて各種リサイクル法が整備されている。しかし,対象製品は製造される多種多様な製品に比べると一部に過ぎないが,各企業は資源の有効な活用の促進に努めている。本研究では,企業の廃棄物削減への取り組みについて,CSR報告書の環境会計情報を基に評価および研究を行った。業種別では,電気・ガス供給業が多くの資源循環コストを使用していた。売上高に占める「資源循環コストの比率 (Resource Recycling Cost Ratio:RRC-Ratio)」に着目して分析を行った。その結果,再生資源卸売業における比率が高く,建設業では比率も高く資源循環コストも多いことがわかった。また,新たに,企業が廃棄物の削減への取り組みを判断する指標として「SWM指数 (SWM-Index)」を提案した。

著者

柴田 明徳

出版者

公益社団法人 日本コンクリート工学会

雑誌

コンクリート工学 (ISSN:03871061)

巻号頁・発行日

vol.19, no.7, pp.55-59, 1981-07-15 (Released:2013-04-26)

参考文献数

3

著者

八尾 滋 宮川 淑人 松本 孝芳

出版者

一般社団法人 日本レオロジー学会

雑誌

日本レオロジー学会誌 (ISSN:03871533)

巻号頁・発行日

vol.14, no.2, pp.77-81, 1986-06-20 (Released:2012-11-20)

参考文献数

11

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Linear and nonlinear viscoelastic properties of disperse systems of photosensitive particles were studied in relation to the degree of aggregation of dispersing particles. The disperse system has the characteristic long-time relaxation process attributed to the aggregate structure of dispersing particles. In that relaxation process, the system in which the dispersing particles aggregate in some degree shows markedly nonlinear viscoelasticity. The characteristic relaxation time in the long-time relaxation process can be closely related with the rotational diffusion of the aggregate. It is also shown that the characteristic relaxation time is independent of the dynamic strain amplitude.

著者

高井 良樹 飯野 佑一 堀口 淳

出版者

北関東医学会

雑誌

北関東医学 (ISSN:13432826)

巻号頁・発行日

vol.59, no.3, pp.255-258, 2009-08-01 (Released:2009-09-11)

参考文献数

6

被引用文献数

1

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Mondor病は乳房およびその周囲の前胸壁に多く認められる浅在性の血栓性静脈炎で, 比較的まれな良性疾患である. 当院で3年10ヶ月の間に経験した41例のMondor病症例について検討した. 男女比は1 : 40. 年齢は26~73歳 (平均43.5歳) であった. 発生部位は右 : 左=14 : 27で左に多く, 上腹部から乳房部を経て腋窩に至る部に分布していた. 原因は35例 (85.4%) が特発性であった. 4例は乳癌手術の既往 (術後2ヶ月~ 2年4ヶ月) があり, 1例は乳腺生検後20日, 1例は授乳中であった. 症状は前胸壁皮膚の有痛性の索状物や皮膚陥凹である. ほとんどの症例は経過観察のみで1 ~ 2ヶ月で自然治癒した. Mondor病の診療で大切なのはこの病気について正しい知識を持ち, 他の乳腺疾患を否定することである.

著者

小宮山 櫻子 中原 はるか 津田 幸子 吉村 恵理子 室伏 利久

出版者

一般社団法人 日本めまい平衡医学会

雑誌

Equilibrium Research (ISSN:03855716)

巻号頁・発行日

vol.72, no.6, pp.493-500, 2013-12-31 (Released:2014-02-01)

参考文献数

17

被引用文献数

2 2

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The purposes of this study was to elucidate the clinical characteristics of patients suffering from migraine-associated vertigo (MAV) including results of cervical vestibular evoked myogenic potential (cVEMP) and ocular VEMP (oVEMP). Thirty patients diagnosed as having MAV based on the diagnostic criteria by Sakata et al. were enrolled. We performed a retrospective chart review. These patients underwent medical history taking and examinations including cVEMP, oVEMP and a caloric test. All examinations were performed during a symptom-free interval. Twenty one patients (70%) experienced rotatory vertigo, 5 patients (17%) had floating dizziness and 4 patients (13%) had both. Twenty six patients (87%) reported tinnitus and/or aural fullness unilaterally or bilaterally. Their vertigo or dizziness lasted under 60 minutes in 10 patients (34%), 1 hour to 24 hours in 14 patients (46%), and over one day in 5 patients (17%). Canal paresis in the caloric test was observed in 5 patients (17%). Concerning cVEMP, 4 of the 30 patients (13%) showed absent cVEMPs bilaterally, 2 patients (7%) showed absent cVEMPs reflexes unilaterally, and one (3%) demonstrated decreased cVEMP amplitudes unilaterally. Only one patient showed prolonged cVEMP latencies. Concerning oVEMP, 6 of the 30 patients (20%) had absent oVEMP reflexes bilaterally, 2 (7%) had absent oVEMP reflexes unilaterally, and one (3%) had decreased oVEMP amplitudes unilaterally. In 2 patients prolonged oVEMP latencies were observed. No significant correlation was observed among cVEMP, oVEMP and the caloric test. This study showed abnormal vestibular reflexes could be shown by oVEMP as well as the caloric test and cVEMP. It was suggested that a portion of those patients with MAV have abnormal otolith-ocular reflexes.

著者

中下 靜夫

出版者

一般社団法人 日本内分泌学会

雑誌

日本内分泌学会雑誌 (ISSN:00290661)

巻号頁・発行日

vol.26, no.10, pp.275-289, 1951-01-20 (Released:2012-09-24)

参考文献数

66

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According to the former opinions it has been thought that the atrophy of the accessory sexual organs and the hypoplasia of the secondary character are directly caused by the lack of testicular hormone.Prof. Tokumitsu has emphasized from his many experiments that deficiency syndromes of an endocrine gland are not merely negative phenomena resulting from the lack of this hormone, but positive phenomena resulfing from functional changes of other endocrine glands.The writer has injected the serum of the rabbit every day for over 3 weeks after castration, into mice (0.1cc. per 10g. bodyweight) and cocks (2cc. per kg. bodyweight) and studied the development of the sexual glands and the cockscomb. Consequently he has found an active substance in the serum from the castrated rabbit's ear vein which controls the development of the testis and the accessory sexual organs of the mice, and controls the development of their secondary character and cockscomb. The injected castrated cock brings on a stronger atrophy of the cockscomb than the non-injected one. And furthermore it invites the atrophy of the cockscomb without the sexual organ of the injected cock. The active substance is found in the blood of the thyroidectomized, adrenalectomized, thymisectomized or hypophysectomized rabbit after castration. However, it does not appear in the blood of the pinealectomized rabbit after castration and moreover the increase of the dark cells and the hypertrophy of the clear cells are shown in the pineal gland. Therefore the writer believes that the active substance is due to the hyper-product of the pineal gland hormone resulting from the hyperfunction of the same gland. The active substance is insoluble in ether, but soluble in alcohol.

著者

長沢 元夫

出版者

公益社団法人 日本薬学会

雑誌

YAKUGAKU ZASSHI (ISSN:00316903)

巻号頁・発行日

vol.81, no.1, pp.129-138, 1961-01-25 (Released:2010-02-19)

参考文献数

9

被引用文献数

10

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Xi-xin is a crude drug using a subterranean portion of a few plants of Asiasarum genus (Asaraceae family). The most important of its component has been reported as methyleugenol which makes up about 50% of its essential oil but this was found to vary greatly according to habitat of the plant. Some plants contained safrole, eucarvone, and 1, 8-cineol as the chief components. Xi-xin oil from Manchurian plant was proved to contain elemicin, an isomer of cis-asaron.Tu-xi-xin is the dried root of Hetehotropa genus of the same family and used as a substitute for Xi-xin. The chief component of its essential oil had been reported as safrole but elemicin was found to be present as the chief component in some of the crude drug.

出版者

特定非営利活動法人 日本小児外科学会

雑誌

日本小児外科学会雑誌 (ISSN:0288609X)

巻号頁・発行日

vol.50, no.3, pp.547-625, 2014-04-25 (Released:2014-04-19)

著者

中田 朝子 森 俊男 関根 令夫 加賀 勝

出版者

日本武道学会

雑誌

武道学研究 (ISSN:02879700)

巻号頁・発行日

vol.22, no.2, pp.21-22, 1989-11-30 (Released:2012-11-27)

著者

北本 拓 川村 自行

出版者

日本武道学会

雑誌

武道学研究 (ISSN:02879700)

巻号頁・発行日

vol.16, no.1, pp.36-38, 1984-01-31 (Released:2012-11-27)

参考文献数

2

著者

伊藤 浩二 加藤 和弘

出版者

公益社団法人 日本造園学会

雑誌

ランドスケープ研究 (ISSN:13408984)

巻号頁・発行日

vol.70, no.5, pp.449-452, 2007-03-30 (Released:2009-03-31)

参考文献数

20

被引用文献数

7 7

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To clarify the interrelations between various semi-natural grassland types (verge meadows, ditch walls, paddy levees, fallow fields, abandoned rice fields and farm roads) maintained by traditional agricultural management methods, we conducted vegetation investigation in a ‘Yatsuda’ rural landscape, and compared species richness between the grassland types using the rarefaction method. Each grassland type was characterized by indicator species extracted by INSPAN and life-form composition of the grassland types were compared. The results of rarefaction method showed that the paddy levees located between paddy field and hillslope were species-rich grassland habitat, as rich as the verge meadows which were cutting grassland adjacent to woodland. The abandoned rice fields, the verge meadows and the paddy levees were consisted of different species groups, and similarity indices were not large between these grassland types. Therefore, in Yatsuda rural landscapes, we suggested that the different types of grasslands should be maintained by traditional agricultural management methods for conserving plant diversity.

著者

佐々木 一裕 榛沢 和彦 山村 修 柴田 宗一 谷口 哲 柏谷 元 寺山 靖夫

出版者

公益財団法人 日本心臓財団

雑誌

心臓 (ISSN:05864488)

巻号頁・発行日

vol.44, no.7, pp.955-956, 2012 (Released:2013-12-26)

参考文献数

6

被引用文献数

1

著者

巽 申直 野村 知弘 村山 勤治 小田 佳子 富樫 泰一 服部 恒明

出版者

日本武道学会

雑誌

武道学研究 (ISSN:02879700)

巻号頁・発行日

vol.33, no.2, pp.16-23, 2001-01-31 (Released:2012-11-27)

参考文献数

30

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The purpose of this study was to clarify the unique kendo moves used by the All Japan Kendo Champion Masahiro Miyazaki, six-time winner of the all Japan Kendo Championship.Using a direct linear transformation method, traces of the locomotion movement of the kendo players were measured. These measures permitted analysis of the spatial distances between the two competitors (i. e., ma-ai) during their matches. Distribution curves revealed two main types of ma-ai, one which had a higher peak position of sword-guard tangle (i. e., tuba-zeriai), and the other (i. e., issoku-itto-no-maai), which is the distance which enables players to either strike the opponent by taking one step forward and to evade the opponent's striking one step backward. Longitudinal data of 47 matches over 10 years (1990-1999) revealed that:1) The percentage occurrence of Miyazaki's issoku-itto-no-maai was lower relative to tsuba-zeriai, which is typical of all such players.2) The number of Miyazaki's offensive and defensive movements from issoku-itto-no-maai was higher than that of all such players.3) The total times of confrontation in Miyazaki's issoku-itto-no-maai were significantly lower than that of all other players. Namely, his initial offensive movement is much earlier than that of all other players.4) Miyazaki's percentage occurrence of issoku-itto-no-maai tended to increase year by year, coupled with a decrease in the number of offensive and defensive movement from ma-ai.

著者

Takuji Koshimizu

出版者

The Botanical Society of Japan

雑誌

植物学雑誌 (ISSN:0006808X)

巻号頁・発行日

vol.52, no.613, pp.32-39, 1938 (Released:2007-05-24)

参考文献数

48

被引用文献数

1 3

著者

浅尾 恒徳 上田 恵亮 村尾 哲 帖佐 博文

出版者

西日本整形・災害外科学会

雑誌

整形外科と災害外科 (ISSN:00371033)

巻号頁・発行日

vol.43, no.2, pp.712-715, 1994-03-25 (Released:2010-02-25)

参考文献数

4

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We heve treated 4 cases with pyogenic cervical spondylitis associated with paralysis over the last 5 years. Three males and 1 female were treated, ranging in age from 56 to 74 years. Anterior spinal fusion was carried out in 2 cases, and anterior and posterior spinal fusion were concomitantly used in 2 cases. Magnetic resonance imaging (MRI) was very useful in deciding on the surgical technique because it clearly showed the range of destruction of the vertebral body, degree of oppression of dural duct and range of extension of inflammation. Early favorable prognosis was obtained in 2 cases which had anterior spinal fusion of 3 intravertebral spaces plus the combined use of posterior spinal fusion. Kyphosis was not observed, and favorable osteorrhaphy was obtained.

著者

成田 和広 鈴木 和雄 李 雨元 相田 貞継 普光江 嘉広 村上 雅彦 草野 満夫

出版者

昭和大学学士会

雑誌

昭和医学会雑誌 (ISSN:00374342)

巻号頁・発行日

vol.56, no.1, pp.112-115, 1996-02-28 (Released:2010-09-09)

参考文献数

9

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症例は68歳, 男性, 上腹部痛による急性腹症にて入院.上部消化管内視鏡検査にて, 胃体部から前庭部に浅いびらんが多発しており, 急性胃粘膜病変と診断された.絶飲食のもと, ファモチジン20mgを12時間毎に投与開始したところ, 翌日より幻覚, 見当識障害, 夜間徘徊等の異常行動出現した.精神障害症状が持続するため4日目にファモチジンを中止したところ, 24時間以内に速やかに同症状が消失した, H2受容体拮抗剤の副作用に, 可逆性の錯乱状態があるが報告例は少ない.本剤の使用頻度は増加傾向にあり, 日常容易に処方され, その副作用は忘れがちである.状況によっては本例のような副作用の出現もあり, 注意深い使用が必要と思われた.