著者

福島 彌六

出版者

公益社団法人 日本セラミックス協会

雑誌

大日本窯業協會雑誌 (ISSN:03669998)

巻号頁・発行日

vol.52, no.614, pp.57-65, 1944-02-01 (Released:2010-04-30)

参考文献数

9

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最近のポルトランド・セメントの成分に就てはその化學的分析の成績を基となし前章にて詳しく論じたので, 茲では全體的に見てその要點を指摘し總括しつゝ成分變動を要約する.1. セメントの灼熱減量は第1囘試料 (現場採集) 1.8-5.1%平均3.20%, 第2囘試料 (工場採集) 0.60-1.8%平均1.2%を表し, 從來の昭和11-13年セメントの1.0%以下に較ぶれば現場のセメントは著しく増加してをり風化したものが多く存在するを認めた. これはセメント包裝用紙の劣化, 輸送の停滯等により風化の機會が多くなつた結果と考へられる.2. 珪酸含有量は第1囘試料19.59-23.04%平均20.95%, 第2囘試料17.63-22.99%平均20.83%を表し, 平均21.0%程と見られるが20%に滿たぬものもあり, 從來の22.0%以上と較ぶれば3-2%程の減少となる. 礬土含有量は第1囘4.67-7.35%, 第2囘7.08-7.86%平均6.05%を表し, 平均6.0%程であり内には6或は1%を超へる高値のものも可成多く從來の礬土が4-6%内に略限られてゐたのに較べて増加したものが多くなつてゐる傾向がある.從來セメントの珪酸, 礬土含有量は各常に略一定してゐたが最近の各セメントは特に礬土につき其量が區々にして低値又は高値なるものが絶へず表れ其多寡に變動が多く見られる様になつた. 此變動は珪酸頻度圖及礬土頻度圖を參照比較すれば一層明瞭である.3. 全石灰は第1囘及第2囘試料にて夫々57.26-63.37%平均61.0%, 61.20-66.23%平均63.51%を表し, 從來の55-56%を常に保つてゐたのに較べて2-4%, 平均3%程の減少と見られる.全石灰含有量にも同様に可成の増減が表れこれは全石灰頻度圖より明瞭である.遊離石灰は從來は0.5-1.5%内にあり平均1.0以下のセメントが大部分と見られてゐたが最近は0.68-5.55%に及び平均2.33%を表し, その内で1.5-3.5%のものが過半數であるに較べて可成増加が目立つてゐる.斯くて最近のセメントの化合石灰量が甚だ減少し, 代つて礬土量が増加したことゝなり, 延いては成分化合物中珪酸石灰鹽類の生成が減少し, 礬土酸石灰鹽を増したことが當然考へられ, セメントの水硬性化合物即ち鑛物組成にも可成變動が與へたと見られる.4. 成分比率に就ては水硬率が共に低下し, 最近は水硬率2.00に滿たざるものも多く現れ, 代つて鐵率が増してゐる. 一般に各成分比率の範圍が從來より廣くなり成分相互の均齊度が喪はれてきた傾がある.5. 現場採集の試料と工場採集のものとを較れば現場のセメントは一般に成績が良好ならず不同がある. 工場採集のセメントは成績が比較的揃つてをり, その一部分には從來に較べて遜色のない品質のものも存在してゐる.6. 計算により求めた水硬性化合物, 即ち鑛物含有量に就いて見ても一般に最近は珪酸石灰鹽が減少し礬土石灰鹽が増加してゐる.3CaO.SiO2は最近のセメントで23.6-56.5%平均40.8%となり從來の40-60%平均50%程と較ぶれば約10%の減少となり, 内には從來餘り見ない40%に滿たざる40-25%程の低値のセメントが約半數を占めてゐた.3CaO.Al2O3, も増加の傾向があり從來此量は略一定してゐたのに較べて最近は各セメントに其多寡に不同が多くなり10%を超へ15%に至る高値のものも現れてゐる.鑛物組成の變動は圖-2を參照することにより明に看取される.7. 石灰, 珪酸, 礬土の三成分に就き化合せざる成分を控除し, 換算した化合量の百分率を表す三元組成圖を見ると, 最近のセメントの三成分組成はCaO 66-70%, SiO2 22-26%, Al2O3 6-11%の比較的廣い範圍内に存在し從來に較べ石灰量減少し礬土量が増加しつゝある傾向が一層明である.8. 一般に最近ポルトランド・セメントは低石灰高礬土質に變動しつゝあり. 之を從來の高石灰低礬土質に較べてむしろ反對の方向を辿つてゐる傾向となりセメントの成分上好しからざる傾向と云へやう.之を要するに, 最近のポルトランド・セメントの質的低下は粗惡炭燃燒に因る遊離石灰及礬土の増加延いては全成分割合の變動に基くものゝ如く, セメントの主要水硬性化合物なる珪酸石灰鹽, 特に3CaO.SiO2の生成を減じ礬土石灰鹽を増したことゝなり, 其結果セメントの品質に致命的なる打撃を與へ最近のセメントの強度低下の主因をなしてゐると考へられる.此事實はまた目下のセメント製造の實情に照らしてみても明である. 即ち原料なる良質石灰石及粘土の採掘, 精選の不如意, 成分の均等配分の不備等と共に, 特に劣質炭の燃燒に伴ふ燒成温度の低下或は炭分の増加による燒成の不完全が製品の成分に直に關係しセメントの品質に惡彩響を及ぼした結果と見られる.此問題を改良し又解決せざればセメントの品質の向上は困難と見るべきであらう.

著者

西本 敏彦

出版者

一般社団法人 日本数学会

雑誌

数学 (ISSN:0039470X)

巻号頁・発行日

vol.32, no.1, pp.64-69, 1980-02-05 (Released:2008-12-25)

参考文献数

15

著者

高津 春繁

出版者

日本言語学会

雑誌

言語研究 (ISSN:00243914)

巻号頁・発行日

vol.1939, no.1, pp.59-71, 1939-01-25 (Released:2010-11-26)

著者

賀数 康弘

出版者

日本耳科学会

雑誌

Otology Japan (ISSN:09172025)

巻号頁・発行日

vol.18, no.1, pp.2-6, 2008-03-21 (Released:2011-06-17)

参考文献数

9

著者

Hiroaki Kurahashi Masami Watanabe Morito Sugimoto Yuichi Ariyoshi Sabina Mahmood Motoo Araki Kazushi Ishii Yasutomo Nasu Atsushi Nagai Hiromi Kumon

出版者

(社)日本内分泌学会

雑誌

Endocrine Journal (ISSN:09188959)

巻号頁・発行日

pp.EJ13-0203, (Released:2013-09-18)

被引用文献数

1 42

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Gender identity disorder (GID) results from a disagreement between a person’s biological sex and the gender to which he or she identifies. With respect to the treatment of female to male GID, testosterone replacement therapy (TRT) is available. The uric acid (UA) level can be influenced by testosterone; however, the early effects and dose-dependency of TRT on the serum UA concentration have not been evaluated in this population. We herein conducted a dose-response analysis of TRT in 160 patients with female to male GID. The TRT consisted of three treatment groups who received intramuscular injections of testosterone enanthate: 125 mg every two weeks, 250 mg every three weeks and 250 mg every two weeks. Consequently, serum UA elevation was observed after three months of TRT and there was a tendency toward testosterone dose-dependency. The onset of hyperuricemia was more prevalent in the group who received the higher dose. We also demonstrated a positive correlation between increased levels of serum UA and serum creatinine. Since the level of serum creatinine represents an individual’s muscle volume and the muscle is a major source of purine, which induces UA upregulation, the serum UA elevation observed during TRT is at least partially attributed to an increase in muscle mass. This is the first study showing an association between serum UA elevation and a TRT-induced increase in muscle mass. The current study provides important information regarding TRT for the follow-up and management of the serum UA levels in GID patients.

著者

Tae-Ho CHUNG Hee-Dong KIM Young-Sun LEE Cheol-Yong HWANG

出版者

公益社団法人 日本獣医学会

雑誌

Journal of Veterinary Medical Science (ISSN:09167250)

巻号頁・発行日

pp.13-0223, (Released:2013-09-20)

被引用文献数

5 14

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Helicobacter spp. may have multiple routes of transmission. It is unclear, however, whether the agent is zoonotic and therefore transmitted from an animal reservoir, including dogs. The aim of this population-based study was to assess the relationship between pet ownership or frequent exposure to dogs and Helicobacter spp. infection, especially focusing on HHLO-2 (Helicobacter heilmannii-like organisms type 2) in saliva and feces samples in Korea, using non-invasive genus/species-specific PCR. One hundred twenty-four eligible human subjects and 39 dogs participated in this study. Relativity of contact with dogs and Helicobacter spp. infection diagnosed by genus-specific PCR showed a statistically significant result (P<0.01), but in the relativity analyses between contact with dogs and H. pylori, H. felis and H. bizzozeronii infections diagnosed using species-specific PCR, only Helicobacter felis showed a statistically significant result. Although H. pylori infection showed a statistically significant relativity, no statistically significant association was found between veterinarian subjects and Helicobacter. spp., H. felis and H. bizzozeronii infections. On performing risk factor analyses of HHLO-2 infection by transmission, using matching species, between HHLO-2-positive dog owners and HHLO-2-positive dogs, Helicobacter felis infection showed an extremely significant relativity (P<0.0001) and Helicobacter bizzozeronii may also be a possible significant risk factor (P<0.01). These results suggest that HHLO-2 infection might be a zoonotic infection, because continuous contact with dogs was proved to be correlated with human H. felis and H. bizzozeronii infections in this study.

著者

Makoto Katori Masataka Majima

出版者

(公社)日本薬理学会

雑誌

Journal of Pharmacological Sciences (ISSN:13478613)

巻号頁・発行日

vol.100, no.5, pp.370-390, 2006 (Released:2006-06-24)

参考文献数

168

被引用文献数

12 33

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It is widely accepted that a high sodium intake triggers blood pressure rise. However, only one-third of the normotensive subjects were reported to show salt-sensitivity in their blood pressure. Many factors have been proposed as causes of salt-sensitive hypertension, but none of them provides a satisfactory explanation. We propose, on the basis of accumulated data, that the reduced activity of the kallikrein-kinin system in the kidney may provide this link. Renal kallikrein is secreted by the distal connecting tubular cells and all kallikrein-kinin system components are distributed along the collecting ducts in the distal nephron. Bradykinin generated is immediately destroyed by carboxypeptidase Y-like exopeptidase and neutral endopeptidase, both quite independent from the kininases in plasma, such as angiotensin converting enzyme. The salt-sensitivity of the blood pressure depends largely upon ethnicity and potassium intake. Interestingly, potassium and ATP-sensitive potassium (KATP) channel blockers accelerate renal kallikrein secretion and suppress blood pressure rises in animal hypertension models. Measurement of urinary kallikrein may become necessary in salt-sensitive normotensive and hypertensive subjects. Furthermore, pharmaceutical development of renal kallikrein releasers, such as KATP channel blockers, and renal kininase inhibitors, such as ebelactone B, may lead to the development of novel antihypertensive drugs.

著者

寺田 至

出版者

一般社団法人 日本数学会

雑誌

数学 (ISSN:0039470X)

巻号頁・発行日

vol.41, no.4, pp.358-364, 1989-11-09 (Released:2008-12-25)

参考文献数

4

著者

Kang Sung Lee Eunhye Ko Chae Gil Lim

出版者

理学療法科学学会

雑誌

Journal of Physical Therapy Science (ISSN:09155287)

巻号頁・発行日

vol.25, no.3, pp.337-340, 2013-03-25 (Released:2013-05-10)

参考文献数

21

被引用文献数

2 2

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[Purpose] The aim of this study was to investigate the EMG amplitude of the gluteus maximus (GMax) and medius (GMed) during 6 exercises with and without a pelvic belt. [Subjects] Twenty healthy males were recruited. [Methods] The belt was positioned below the anterior superior iliac spine. Surface EMG was used to measure the GMax and GMed activity of the dominant limb during exercise. The percentage of the EMG amplitude relative to maximal voluntary isometric contraction was analyzed with a mixed within-between subjects analysis of variance (ANOVA). [Results] This study showed significantly increased GMax activity in the pelvic belt condition as a main effect. However, there was no significant effect on GMed activity except with the hip clam. [Conclusion] The pelvic belt significantly improved GMax activity during exercises in contrast to the GMed activity. When treating people with weakness of gluteal muscles, the functional specific exercises with a pelvic belt have the beneficial effect of associated muscle strengthening.

著者

鎌田 春彦

出版者

公益社団法人 日本薬学会

雑誌

YAKUGAKU ZASSHI (ISSN:00316903)

巻号頁・発行日

vol.133, no.9, pp.925-930, 2013 (Released:2013-09-01)

参考文献数

13

被引用文献数

1 1

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Biopharmaceuticals represent new generation drugs that are more effective than conventional low molecular weight medicines for the treatment of cancer and other refractory diseases. In order to develop biopharmaceuticals it is critically important to explore suitable target molecules both for the diagnosis and treatment of disease. However, the choice of effective biomarker or drug target is often the most difficult part of the drug development process. Target discovery typically involves ‘omics’ techniques such as genomics, gene chip analysis and proteomics. Of these, proteomics is particularly important because proteins often comprise the final biomarker or drug target in the clinical sample (e.g., tissue or blood). Comprehensive proteomic analysis involves the identification of target proteins with different levels of expression between two states and is extremely useful at selecting promising candidates. Technology is then applied to further narrow down the list of relevant proteins. Here, I would like to introduce our novel procedure, termed “antibody proteomics technology”, which can generate monoclonal antibody from a minute amount (i.e., nanogram level) of protein. Antibody proteomics technology can be used to easily identify suitable target molecules in order to develop effective biomarkers and drug targets.

著者

波多野 澄雄

出版者

財団法人 日本国際政治学会

雑誌

国際政治 (ISSN:04542215)

巻号頁・発行日

vol.2011, no.166, pp.166_156-159, 2011-08-30 (Released:2013-09-19)

著者

中村 春木

出版者

一般社団法人 日本生物物理学会

雑誌

生物物理 (ISSN:05824052)

巻号頁・発行日

vol.53, no.1, pp.044-046, 2013 (Released:2013-01-29)

参考文献数

10

被引用文献数

2

著者

樋上 弓子 樋上 茂 竹内 裕美 生駒 尚秋

出版者

耳鼻と臨床会

雑誌

耳鼻と臨床 (ISSN:04477227)

巻号頁・発行日

vol.46, no.4Supplement3, pp.S174-S176, 2000-01-20 (Released:2013-05-10)

参考文献数

6

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閉塞性睡眠時無呼吸症候群 (OSAS) の気道閉塞部位は軟口蓋部と舌根部が多く、声門部が原因となることはまれである。われわれは睡眠中のみに声門開大障害が生じたOSASの1例を経験したので報告した。症例は68歳男性で主訴はいびきであった。内視鏡検査では、覚醒時の声帯の可動性は良好であったが、睡眠中には吸気時に声門は閉鎖し、呼気時も声帯の開大は副正中位までに制限されていた。中咽頭食道内圧測定では、無呼吸時の中咽頭圧は全く変動しなかったが食道内圧は最大-23.0cm H2Oまで陰圧化し、舌根部以下の狭窄が示唆された。中枢性疾患の合併を伴わず、特発性Gerhardt症候群と診断した。

著者

Naoyuki Sugano

出版者

日本大学歯学部

雑誌

Journal of Oral Science (ISSN:13434934)

巻号頁・発行日

vol.54, no.1, pp.1-5, 2012 (Released:2012-03-30)

参考文献数

24

被引用文献数

4 23

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Despite its important role in the control of periodontal disease, mechanical plaque control is not properly practiced by most individuals. Therefore, adjunctive chemical plaque control using chlorhexidine and antibiotics has also been suggested as an additional therapeutic strategy to augment mechanical plaque control. However, the additional effects of adjunctive antibiotic therapy are small, and topical chlorhexidine therapy is not without side effects. Given current limitations, new approaches for the control of biofilm are required. The new therapeutic approaches discussed in this review are divided into two categories: probiotics and vaccines. Probiotics is an interesting new field of periodontology research that aims to achieve biological plaque control by eliminating pathogenic bacteria. In addition, passive immunization using egg yolk antibody raised against periodontal pathogens may be an effective approach for the treatment of periodontitis. Further study to evaluate the possible effects of these biological plaque control methods against periodontal disease is warranted. (J Oral Sci 54, 1-5, 2012)

著者

Shigenobu Inami Masamichi Takano Masanori Yamamoto Daisuke Murakami Kenichiro Tajika Kenji Yodogawa Shinya Yokoyama Norihiko Ohno Takayoshi Ohba Junko Sano Chikao Ibuki Yoshihiko Seino Kyoichi Mizuno

出版者

一般社団法人 インターナショナル・ハート・ジャーナル刊行会

雑誌

International Heart Journal (ISSN:13492365)

巻号頁・発行日

vol.48, no.6, pp.725-732, 2007 (Released:2007-12-27)

参考文献数

25

被引用文献数

34 70

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It has been reported that green tea consumption reduces the risk of coronary artery disease and cardiac events. Catechin is a major constituent of Japanese green tea and an antioxidant. Lipids and oxidization of low-density lipoprotein cholesterol (LDL-C) play important roles in atherosclerosis. Therefore, we evaluated the effect of catechin intake on the lipid profile and plasma oxidized LDL. The study population consisted of 40 healthy adult volunteers (10 men, 30 women). Catechin was extracted from green tea leaves. The subjects were randomly divided into two groups, a catechin group (n = 29) and a control group (n = 11). In the catechin group, catechin (500 mg: equivalent to 6 or 7 cups of green tea) was administered orally. Venous blood samples were obtained before eating a meal at the start and after 4 weeks without any lifestyle modification. Plasma oxidized LDL assay was performed with a sandwich-type enzyme immunoassay using anti-oxidized phosphatidylcholine monoclonal antibody. The baseline lipid profiles and tea consumptions were similar between the two groups. Plasma oxidized LDL was significantly decreased after catechin administration (from 9.56 ± 9.2 to 7.76 ± 7.7 U/mL, P = 0.005), while plasma LDL-C, triglyceride, and HDL-C concentrations did not change. Catechin decreased the plasma oxidized LDL concentration without significant change in plasma LDL concentration. The mechanism of the beneficial effects of green tea on coronary artery disease might result from a decrease in plasma oxidized LDL.

著者

Junko Sano Shigenobu Inami Koji Seimiya Takayoshi Ohba Shunta Sakai Teruo Takano Kyoichi Mizuno

出版者

日本循環器学会

雑誌

Circulation Journal (ISSN:13469843)

巻号頁・発行日

vol.68, no.7, pp.665-670, 2004 (Released:2004-06-25)

参考文献数

38

被引用文献数

52 91

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Background Green tea, a popular beverage in Japan, contains many polyphenolic antioxidants, which might prevent atherosclerosis. This study was designed to determine whether the consumption of green tea is proportionately associated with a decreased incidence of coronary artery disease (CAD) and the cardiovascular and cerebrovascular prognosis. Methods and Results The study group comprised 203 patients who underwent coronary angiography (109 patients with significant coronary stenosis and 94 patients without). Predictors for CAD were analyzed and the patients' cardiovascular and cerebrovascular events were followed. Green tea consumption was significantly higher in patients without CAD than in those with CAD (5.9±0.5 vs 3.5±0.3 cups/day; p<0.001). An inverse relationship between the intake of green tea and the incidence of CAD was observed (p<0.001). The green tea intake per day was an independent predictor for CAD based on a multivariate logistic regression analysis (odds ratio: 0.84 and 95% confidence interval: 0.76-0.91). In contrast, the green tea intake was not a predictor of cardiovascular and cerebrovascular events based on the Cox proportional hazard model. Conclusions Green tea consumption was associated with a lower incidence of CAD in the present study population in Japan. Therefore, the more green tea patients consume, the less likely they are to have CAD. (Circ J 2004; 68: 665 - 670)

著者

Christopher R. MARTELL

出版者

プシコロギア会

雑誌

PSYCHOLOGIA (ISSN:00332852)

巻号頁・発行日

vol.56, no.2, pp.131-137, 2013 (Released:2013-08-30)

参考文献数

24

被引用文献数

2 5

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Behavioral treatments for depression that originated in the early 1970s have emerged again in the early 21st century known as Behavioral Activation (BA). The current formulation of BA is based on the earlier work, and represents a refinement rather than a completely new approach. As the treatment has gained in popularity, several misconceptions and misunderstandings about the treatment have developed: that it is unique; that there are multiple, substantially different forms of BA; that the treatment requires specific strategies be used in all cases; and that the treatment is conducted in a lock-step fashion. In this article one of the primary authors of the main texts/protocols for BA argues that these are misconceptions and that BA needs to remain a treatment driven by a good functional analysis of the individual case, and that, at the most basic level, BA is just good behavior therapy for depression.

著者

Ryutaroh Matsumoto

出版者

(社)電子情報通信学会

雑誌

IEICE Communications Express (ISSN:21870136)

巻号頁・発行日

vol.2, no.8, pp.343-346, 2013-08-15 (Released:2013-08-15)

参考文献数

5

被引用文献数

4

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We propose a Gilbert-Varshamov-type existential bound for the relative dimension length profile and the relative generalized Hamming weight of nested pairs of linear codes.

著者

稲葉 智彦 向井 直樹

出版者

一般社団法人 日本体育学会

雑誌

体育学研究 (ISSN:04846710)

巻号頁・発行日

vol.55, no.1, pp.147-155, 2010 (Released:2010-07-20)

参考文献数

20

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When a unilateral transfemoral amputee performs sprinting, alternation between the sound limb and the prosthetic limb causes asymmetrical motion. One of the causes of the asymmetrical sprinting performance is that the knee joint of the prosthetic limb does not flex easily due to strong flexion resistance in order to prevent giving way during the landing by extension delay of the shank after flexion in the swing phase. This study examined whether the prosthetic limb performs the same motion as the sound limb working with the movements of the hip joint and other areas by setting the knee joint to allow easier flexion when relaxing the flexion-and-extension resistance of the knee joint in the swing phase. Moreover, when possible, we also examined whether this allows more rational motion than during sprinting when the flexion resistance of the knee joint is set strongly. The composition of the prosthetic limb used for the trial was an IRC (Ischial Ramal Containment) suction socket, high-activity hydraulic knee joint (model 3R55; Otto Bock, Duderstadt, Germany) in which the flexion-and-extension resistance was relaxed, in combination with an energy-storing prosthetic foot for running (model Sprinter; Otto Bock, Duderstadt, Germany). Sprinting was performed by a unilateral transfemoral amputee using this prosthetic limb after the subject had learned how to sprint while using it. Sprinting performance was filmed (30 fps) with a video tape recorder (DCR-PC101 NTSC, Sony Corporation, Tokyo, Japan), and we compared the motion of the prosthetic foot and the knee joint angle with the motion of the sound limb. Moreover, the motion was also compared with that during sprinting when the flexion-and-extension resistance of the knee joint was set strongly. As a result of the relaxed setting of the prosthetic knee joint, it was shown that the prosthetic limb performed the same motion as a sound limb without giving way at landing by extension delay of the shank of the prosthetic limb during the swing phase. Moreover, it was shown that this setting facilitates more rational motion than that during sprinting with a stronger setting for the flexion resistance of the knee joint.

著者

Kazuhiko Higashida Izumi Tabata Mitsuru Higuchi Shin Terada

出版者

一般社団法人日本体力医学会

雑誌

The Journal of Physical Fitness and Sports Medicine (ISSN:21868131)

巻号頁・発行日

vol.2, no.3, pp.355-360, 2013-08-25 (Released:2013-09-08)

参考文献数

42

被引用文献数

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Skeletal muscle is the primary site of glucose uptake in humans. Glucose transport activity, which is the rate-limiting step in muscle glucose metabolism, is linearly related to the content of the GLUT-4 isoform of the glucose transporter. Therefore, the level of GLUT-4 in skeletal muscle may be an important determinant of whole-body glucose disposal. It has been well documented that long-term, low- to moderate-intensity endurance exercise training induces an increase in muscle GLUT-4 content. However, emerging evidence suggests that an adaptive increase in GLUT-4 occurs even after a single acute bout of exercise or high-intensity intermittent exercise training. Recent findings also indicate that nutritional status affects GLUT-4 expression in skeletal muscle. This review provides an overview of the effects of exercise and nutritional status on GLUT-4 content in skeletal muscle, and summarizes recent progress in elucidating the molecular regulation of muscle GLUT-4 gene expression by exercise and nutritional stimuli.