著者

逸見 隼 牧野 聖也 狩野 宏 浅見 幸夫

出版者

Japan Society of Nutrition and Food Science

雑誌

日本栄養・食糧学会誌 (ISSN:02873516)

巻号頁・発行日

vol.71, no.2, pp.99-102, 2018 (Released:2018-04-16)

参考文献数

15

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我が国では高齢化の進展に伴い, 健康寿命の延伸が課題となっている。この課題解決において健康機能を有する食品が果たすべき役割は大きい。我々は, 日常的に気軽に摂取できるヨーグルトを介した健康増進を目指し, 免疫賦活作用を有する菌体外多糖体を高産生する乳酸菌としてOLL1073R-1株を選抜した。本株で発酵したヨーグルトの摂取はマウスの脾臓細胞のインターフェロン-γ (IFN-γ) 産生を誘導し, ナチュラルキラー (NK) 活性増強効果や抗インフルエンザウイルス活性を発揮した。またヒトでは健常高齢者の風邪症候群の罹患リスクの低減効果や健常成人のインフルエンザワクチン接種後の抗体産生の増強効果を見出し, 自然免疫, 獲得免疫の両面から免疫機能を高め, 感染症に対する防御効果を増強することが示唆された。一方で, 気温変化の大きい季節の変わり目時期における疲労感を軽減することも示され, 体調管理に広く有用であることが明らかとなった。

著者

佐々木 雄一 佐々木 祐典 佐々木 優子 中崎 公仁 岡 真一 浪岡 隆洋 浪岡 愛 柿澤 雅史 本望 修

出版者

日本脳循環代謝学会

雑誌

脳循環代謝(日本脳循環代謝学会機関誌) (ISSN:09159401)

巻号頁・発行日

vol.28, no.2, pp.281-289, 2017 (Released:2017-08-25)

参考文献数

20

被引用文献数

1

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脳梗塞は本邦における要介護者の原因疾患第1位であり,新しい治療法の開発が望まれてきた.我々は骨髄間葉系幹細胞(mesenchymal stem cell: MSC)の移植が,脳梗塞を含む神経疾患に対して治療効果を発揮することを報告してきた.現在,基礎・臨床研究の良好な結果を受けて,自己培養MSCの静脈投与による医師主導治験を,脳梗塞および脊髄損傷に対して実施している.MSC移植の治療効果によって,失われた運動・感覚機能が回復する過程には,脳の可塑性の変化が大きく関わっていることが示唆されている.また,我々は実験的脳梗塞モデルに対するMSC移植にリハビリテーションを付加した結果,運動能力のさらなる回復が得られることを報告した.この基礎研究の結果から,MSC治療が臨床で実用化された暁には,再生医療におけるリハビリテーションの役割はますます重要になると考えられる.

著者

井上 真由美

出版者

一般社団法人 軽金属学会

雑誌

軽金属 (ISSN:04515994)

巻号頁・発行日

vol.18, no.9, pp.483-491, 1968-09-30 (Released:2008-10-30)

参考文献数

33

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Aluminum corrosion induced by microbial contamination of jet fuel has become one of the most important troubles. The object of the present work is to study the corrosion of aluminum caused by the growth of fungi isolated from jet fuel system. Of the fungi isolated, Cladosporium resinae appeared to be the most predominant. Many kinds of filamentous fungi were obtained from slime of jet fuel, water layer of storage tank, and sludges on stringer and lower panel of integral fuel tank of YS-11 jet planeResults obtained were as follows.(1) After 330 day incubation, exfoliation and corrosion occurred with small blisters on the surface of aluminum alloy, 6061 specimen.(2) The cross section of the 6061 specimen indicated that the corrosion pits by Cladosporium resinae were extensively evident thoughout the aluminum body.(3) The specimens of high purity aluminum (1099 and 1100), anodized aluminum, and aluminum alloy 5052 were severely damaged by the attack of the fungus.(4) An extruded bar of 1100 was also attacked by Cladosporium resinae. Corrosion pits began to develop after 30 day culture of the fungus.(5) Large amounts of sludge deposits were found on the stringer and lower skin panel of the integral tank of YS-11 jet plane. Widespread corrosions were found in the area covered by the growth of the fungus.(6) Discussions were also made over the development of tests for the effects of protective coatings.

著者

岡田 庄生

出版者

日本マーケティング学会

雑誌

マーケティングジャーナル (ISSN:03897265)

巻号頁・発行日

vol.39, no.2, pp.61-67, 2019-09-27 (Released:2019-09-27)

参考文献数

35

被引用文献数

7

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企業の新製品開発プロセスに参加するユーザー(消費者)が増えている。企業はユーザーから製品アイデアを得るだけでなく,ユーザーのアイデアから生まれた製品であるという情報を表示することで,その表示を見た消費者の購買意向を高めることが可能である。本稿では,製品アイデアの発案者が企業ではなくユーザーであることを明示することで,消費者が購買の意思決定に影響を与える効果を「発案者効果(Originator Effect)」と名付け,その既存研究を整理する。発案者効果の既存研究は,以下の2つの潮流,すなわち(1)発案者効果の背景を探る「媒介要因研究」,(2)発案者効果が失われる条件を探る「境界条件研究」に分類して整理できる。また,発案者効果研究の発展のため,今後の研究課題として,(1)媒介要因研究の課題,(2)境界条件研究の課題,(3)両研究における研究方法の課題を提示した。

著者

村嶋 恵 菊池 有利子 野見山 哲生 熊谷 奈美 大前 和幸 渡邊 昌 赤倉スタディグループ

出版者

The Japanese Society for Hygiene

雑誌

日本衛生学雑誌 (ISSN:00215082)

巻号頁・発行日

vol.59, no.1, pp.31-37, 2004-01-15 (Released:2009-02-17)

参考文献数

21

被引用文献数

1 2

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Objective: Absorption of cadmium is increased by deficiency of iron in animals, but it is uncertain that the same phenomenon occurs in humans. The purpose of this study is to investigate the relationship between cadmium and iron in the body and to evaluate the influence of dietary habits.Methods: Twenty-five healthy women, aged 20-23 years, were selected by excluding those with renal disease and habitual constipation. They participated in the dietary intervention study to estimate tolerable weekly intake of Cd for 3 weeks in the same dormitory. At 3 months before, at 0 Day, at the 12th Day of the study and 9 months after the study, health check-ups were performed, and Cd in the blood and urine, hemoglobin (Hb), serum iron (iron) and serum ferritin (ferritin) were measured.Results: Cd concentration in the blood (B-Cd) showed a significant correlation with Cd concentration in the urine (U-Cd), and inverse correlation with the body iron storage, such as Hb, iron and ferritin. A food frequency questionnaire showed that no subject showed insufficient dietary intake of iron. Subjects who had eaten grain, millet and brown rice showed higher levels of B-Cd and U-Cd and low levels of Hb, iron and ferritin.Conclusion: Absorption of Cd tended to increase according to a low level of body iron storage among healthy young women.

著者

京野 洋子

出版者

日本エアロゾル学会

雑誌

エアロゾル研究 (ISSN:09122834)

巻号頁・発行日

vol.11, no.3, pp.211-217, 1996-09-20 (Released:2010-07-08)

参考文献数

37

著者

呉 炳宇

出版者

The Japan Society for Oriental Medicine

雑誌

日本東洋医学雑誌 (ISSN:02874857)

巻号頁・発行日

vol.45, no.4, pp.893-898, 1995-04-20 (Released:2010-03-12)

参考文献数

15

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帯状疱疹患者52例を針灸で治療し, 49例の患者 (対照群) は漢方薬で治療した。鎮痛効果の尺度として視覚的表現スケール (VAS) を用いた。針灸群は東洋医学の症状鑑別法に基づき, 証による本治法的な針を実施した。それと共に, 皮膚病変部の周囲を取り囲む針治療を実施し, 次いで灸を30分間行った。漢方薬群は肝胆湿熱型には龍胆潟肝湯を投与し, 肝鬱気滞型には逍遥散を投与し, 脾経湿熱型には胃苓湯を与えた。針灸群では, 平均3.8回の治療後に痛みが消えたが, 漢方薬群では, 鎮痛効果の発現に平均5日かかり, しかも3例では無効であった。鎮痛効果の発現率は針灸群で有意に良好であった。針は経絡の気と血を疏通することにより痛みをコントロールすると考えられる。針はまた免疫機能を高めてウイルスの活動を抑制し, それにより鎮痛効果を現すとも考えられる。針灸は帯状疱疹患者の痛みを有意に改善させた。針灸は鎮痛作用を有するといえる。

著者

藤田 直博 森野 一英 稲留 将人

出版者

一般社団法人 日本風力エネルギー学会

雑誌

風力エネルギー利用シンポジウム (ISSN:18844588)

巻号頁・発行日

vol.37, pp.307-310, 2015 (Released:2017-02-01)

著者

野村 泰之 濱田 敬永 斎藤 雄一郎 吉田 晋也 遠藤 壮平 鴫原 俊太郎 木田 亮紀

出版者

Japan Society for Equilibrium Research

雑誌

Equilibrium Research (ISSN:03855716)

巻号頁・発行日

vol.57, no.6, pp.608-614, 1998 (Released:2009-10-13)

参考文献数

17

被引用文献数

2 2

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Recently, because of the development of MRI, it is becoming apparent that there are some cases of cerebellar vascular disorder in the posterior cranial fossa among cases of sudden onset of rotatory vertigo. We reported two cases of sudden onset of rotatory vertigo caused by cerebellar infarction in the territory of the posterior inferior cerebellar artery (PICA) due to cervical occlusive injuries.Case 1. A 48-year-old male sustained a slight whip lash injury and after ten hours, experienced rotatory vertigo and hoarseness. When he came to our hospital, we could only detect hoarseness. However, vascular disorder in the posterior cranial fossa was suggested by the interview. MRI revealed left cerebellar and medulla oblongata infarction.Case 2. A 29-year-old male felt rotatory vertigo and vomited after clicking his neck. Upon closer examination, pure rotatory spontaneous nystagmus, sensory disorder accompanied by sensory dissociation in his face and disability in standing and walking were found, suggesting vascular disorder in the posterior cranial fossa. MRI showed infarction in the left inferior cerebellar region, vermis and left lateral-dorsal medulla oblongata. A dissecting aneurysm in the vertebral artery was found on subsequent angiography.In the Japanese literature, we could find only nine reported cases of cerebellar vascular disorder in the posterior cranial fossa due to the cervical occlusive injuries, in addition to our two cases.The severity of injuries and the period until onset of diagnostic symptoms varied. Therefore, tracing cerebellar vascular disorders due to cervical occlusive injury required not only neurological and neuro-otological findings, but also attention to the history of the original injury and the development of subsequent symptoms. Without a careful interview, it is very difficult to correctly establish the cause of the disorder.

著者

山田 雅弘

出版者

一般社団法人 照明学会

雑誌

照明学会誌 (ISSN:00192341)

巻号頁・発行日

vol.71, no.12, pp.712-718, 1987-12-01 (Released:2011-07-19)

参考文献数

26

被引用文献数

1

著者

牧 幸輝

出版者

Business History Society of Japan

雑誌

経営史学 (ISSN:03869113)

巻号頁・発行日

vol.46, no.2, pp.2_49-2_73, 2011 (Released:2014-09-10)

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This article aims to explore the business vision of Risaburo Toyoda and examine his management of Toyoda Gyoudan [Toyota Industrial Group(TIG)] with emphasis on his entrepreneurial network. Although, Kiichiro Toyoda is well known as the “founder” of Toyota Motor Corporation, in fact, he was not in a position to make final decisions. His brother-in-law, Risaburo, was the president of Toyota Motor Corporation as well as the CEO of TIG. Therefore, the study of TIG including Toyota Motor Corporation must devote special attention to Risaburo. Nevertheless, he has not been judged rightly, and has often been regarded as a hindrance to Toyota's rise in the automobile business. This article aims to reexamine his positive role and the organizational structure of TIG, regarded as a “local Zaibatsu”.One of the most important facets of Risaburo was why he decided to enter the automobile industry. This article shows that in the 1930s, he had predicted the rise of Japan's heavy industry and the decline of its textile industry, and he managed to convert TIG's basic business from textiles to heavy industries.It is well known that Zaibatsu and Emerging Corporate groups were disorganized during the wartime economy due to diversification of affiliated companies. On the other hand, TIG, which was a late-comer in the corporate group, was still primarily controlled by the Toyoda family. A lack of external capital needed to enter the automobile business along with wartime corporate controls had threatened its management structure, but Risaburo secured cooperative stakeholders and reorganized TIG, making Toyota Kinyu [Toyota Finance Company] a holding company. Consequently, TIG kept the family-controlled management structure. In this process, Risaburo made the most of his entrepreneurial network and exercised leadership as the CEO.

著者

金子 良事

出版者

経営史学会

雑誌

経営史学 (ISSN:03869113)

巻号頁・発行日

vol.42, no.3, pp.5-34, 2007-12-25 (Released:2010-03-19)

参考文献数

195

著者

田付 茉莉子

出版者

経営史学会

雑誌

経営史学 (ISSN:03869113)

巻号頁・発行日

vol.37, no.4, pp.1-24, 2003-03-25 (Released:2010-11-18)

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After World War I, Japanese shipping suffered for a long time from an excess of tonnage and severe competition. How could Japanese shipping companies cope with the depression when they were mostly latecomers with less cargo and with small company size? The smaller trampers and owners were disadvantaged by these circumstances because they could not keep sufficient volumes of cargo to operate their ships. Many of them, of course, went bankrupt. But a considerably large number of small companies survived, changing their strategies; some of them found cargo in Near Seas, and others specialised in ownership. It was the growing demands of in the chartering market that offered them new business opportunities.S. Tsutsui and Kaiyo Steamship Co., which he established later, were also small owners. Although a very small owner, he became acquainted with G. Hori, a broker in Yamashita and achieved steady growth, chartering out his ship mainly to Yamashita. Kaiyo Steamship took advantage of the government's “scrap and build policy” and acquired bigger ships, which brought good performance to its business. Kaiyo Steamship grew steadily even under the wartime economic controls and built new ships. They chartered them out to the shipping authority and lost most of them in Japan's defeat in World War II.The growth of small owners was, undoubtedly, a consequence of the development of Japanese shipping. I would like to put emphasis, however, on their contribution. Operators could not have extended their business rapidly and widely without chartering significant tonnage at greatly reduced fees, because they had to play second fiddle in the world shipping market. From this point of view, the activities of small owners are one characteristic of Japanese shipping, though it was evident not only in shipping but also in most manufacturing industries.

著者

長島 修

出版者

経営史学会

雑誌

経営史学 (ISSN:03869113)

巻号頁・発行日

vol.32, no.2, pp.1-26, 1997-07-30 (Released:2009-11-06)

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Japan's iron and steel supply depended upon the import from European countries. Japanese traders could hardly deal with the imported goods because foreign traders almost occupied the iron and steel import dealing. Hikitorisyo (Japanese import trader) intermediated between Japanese distributors and foreign traders. Tsuda Katsugoro who came from Hikitorisyo was one of the most famous distrbutors at Osaka. At first when he worked for Kawasaki Shipbuilding Co., he was headhunted by H.E. Reynell who lived at Kobe and imported wine, spirits and so on. He worked for Reynell and Co. After he was independent of Reynell's financial help because of his bankrupt, Mitui Bank, one of the biggest Japanese bank, gave him the financial help so that Tsuda, though he could refuse foreign trader's financial dependence, deeply had to depend upon Mitsui's finance. He started as the dealer, chiefly sold to government office and Navy, and built his local branches in order to sell foreign goods. He sold ship equipments, steel machines, steel goods and so on, which he imported through foreign merchants and big home traders, to home small traders and iron makers. After his independence from Reynell, he changed his business strategy, firmly dealt with the imported iron and steel and distributed them to local merchants, because he also experienced the risk of Hikitorisyo business in spite of the fact that he made a profit during Japan China War (1894-95). In the Meiji era extending business chance, he was one of the innovative successful merchants in a short period. The small merchant such as Tsuda played an important part in the industrialization in Meiji era.

著者

パトリック フリーデンソン

出版者

経営史学会

雑誌

経営史学 (ISSN:03869113)

巻号頁・発行日

vol.28, no.3, pp.55-65, 1993-10-30 (Released:2009-11-06)

参考文献数

20

著者

老川 慶喜

出版者

経営史学会

雑誌

経営史学 (ISSN:03869113)

巻号頁・発行日

vol.23, no.3, pp.48-61, 1988-10-30 (Released:2009-11-06)

著者

三島 康雄

出版者

経営史学会

雑誌

経営史学 (ISSN:03869113)

巻号頁・発行日

vol.18, no.2, pp.23-51,ii, 1983-07-30 (Released:2009-11-06)

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The origin of Yamaguchi Zaibatsu was opened by Kichirobei Yamaguchi (first) as a draper at Osaka in 1824. Kichirobei (second) changed his business to money-changer in 1863. After the Meiji Restoration, Yamaguchi family established 148th National Bank in 1879, and this bank changed to private. Yamaguchi Bank in 1898. Thereafter, Yamaguchi family invested to Nihon Seimei (life insurance), Osaka Chochiku Ginko (savings bank), Kansai Shintaku (trust company), Kyodo Kasai Kaijo (fire and marin insurance) and so on. Yamaguchi family established Yamaguchi Limited Partnership (¥10, 000, 000) as holding company in 1920 and formed Yamaguchi Zaibatsu. It had developed as a middle-scale financial Zaibatsu untill the end of second World War. The reasons of development were : 1. delegations of management power to able managers, 2. good selections of investments to stable financial and insurance companies, 3. effective utilizing of capitals by reducing the percentage of investment to 10-50% in all capitals of these companies. After the second World War, Yamaguchi Zaibatsu was not designated to Zaibatsu holding company by the Supreme Commander of Allied Forces, but it was going way of dissolution by the huge property tax, and the decreasing of values of holding stocks. Yamaguchi Limited Partnership closed its 30 years history in 1950.

著者

中瀬 寿一

出版者

経営史学会

雑誌

経営史学 (ISSN:03869113)

巻号頁・発行日

vol.1, no.3, pp.28-55,i, 1966-12-20 (Released:2009-11-11)

被引用文献数

10

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No previous analysis has been made of Japanese advertising (advertising industry and capital) from a social scientific point of view. The study of the history of advertising has also been limited to discussions of custom and fashion.This paper outlines the history of Japanese advertising in relation to the growth, development and crises of Japanese capitalism, by considering the functions of advertising in several periods of history. It also shows how and when the advertising agency came about and has continued to develop in Japan.

著者

中村 満 繩田 隆生 松岡 憲二 小田原 良誠 長谷川 汪 田和 宗徳 池内 隆治 大田 信太郎 西牧 紀子

出版者

社団法人 全日本鍼灸学会

雑誌

全日本鍼灸学会雑誌 (ISSN:02859955)

巻号頁・発行日

vol.33, no.2, pp.177-184, 1983-11-01 (Released:2011-05-30)

参考文献数

4

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うつ病は近年増加の一途をたどり, 鍼灸の臨床においても仮面うつ病の患者にしばしば遭遇する。これらの患者には症状の原因である抑うつ感情に対する治療が必要である。今回, 仮面うつ病スクリーニングテストを行い, うつ傾向の者を選び出し鍼治療を行った。方法: Actual Group として百会, 身柱, 心兪, 巨闕, 神門, 三陰交, Placebo Group として陶道, 風門, 水分, 下廉, 懸鐘を選び金鍼にて置鍼10分, 週3回の治療を行った。結果: Actual Group は4週後には71%が正常域に達し, 精神症状と身体症状ともに改善された。Placebo Group では4週後でも64%が抑うつ領域にあった。結論: 精神疾患によく用いられる経穴による鍼治療で精神症状と同時に身体症状の改善をもたらし, うつ状態の寛解か認められた。

著者

今井 正 出濱 和弥 坂見 知子 高志 利宣 森田 哲男 今井 智 山本 義久 岡 雅一

出版者

Japanese Society for Aquaculture Science

雑誌

水産増殖 (ISSN:03714217)

巻号頁・発行日

vol.64, no.3, pp.273-280, 2016-09-20 (Released:2017-09-20)

参考文献数

27

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ろ材の洗浄工程での硝化細菌の活性を維持するために,セラミックスろ材のアンモニア酸化能力に及ぼす乾燥の影響を調べた。25℃でろ材のアンモニア酸化活性測定後,それを海水から出して25℃の異なる3条件(湿度30%と60%の空気中,袋に入れて湿度飽和)で保存した。ろ材を30日目まで保存した後,再度アンモニア酸化活性を測定した。最初の活性と比較して,湿度30%と60%で保存したろ材の活性は,それぞれ6日目と21日目に半減した。湿度30%で保存したろ材の活性は7日目に失われたが,湿度60%では30日目にも3.2%の活性があった。湿度飽和状態では,ろ材は30日目でも約50%の活性を持っており,ろ材のアンモニア酸化細菌と古細菌は最初の状態と同様であった。湿度飽和で保存したろ材を海水に戻し,アンモニア源を添加すると,その活性は3日後に回復した。よって,洗浄工程においてアンモニア酸化活性を維持するためには,ろ材の乾燥を防ぐ必要がある。