著者
石場 光朗
出版者
一般社団法人 日本原子力学会
雑誌
日本原子力学会誌ATOMOΣ (ISSN:18822606)
巻号頁・発行日
vol.63, no.9, pp.653-656, 2021 (Released:2021-09-10)
参考文献数
4

原子力システムを含む重要インフラシステムでのサイバーセキュリティ脅威が顕在化している。また,原子力以外の産業分野では,システムの連携や新規ソフトウェアの脆弱性を利用したサイバー攻撃の脅威が次々と出現し,産業・制御システムを含めたサイバーセキュリティ対策が喫緊の課題になっている。ここでは,他産業分野での動向および対策状況も踏まえ,システムベンダーでの立場から原子力施設におけるサイバーセキュリティ対策について解説する。
著者
Tetsuo KAWAKAMI Simon L. HARLEY
出版者
Japan Association of Mineralogical Sciences
雑誌
Journal of Mineralogical and Petrological Sciences (ISSN:13456296)
巻号頁・発行日
pp.230131b, (Released:2023-04-25)

Boron isotope compositions were measured in kornerupine and tourmaline from lenses consisting primarily of kornerupine, plagioclase and corundum. The lenses occur within hornblende-gneiss or along the boundary between this gneiss and an amphibolite lens at Akarui Point in the Lützow-Holm Complex, Prince Olav Coast, East Antarctica. The peak metamorphic conditions have been estimated to be ~ 800-900 oC and ~ 8-11 kbar. The δ11B compositions of kornerupine, which is interpreted to have been a stable phase at the metamorphic peak, are -11.6 ± 0.4 to -7.8 ± 0.5 ‰ and -9.8 ± 0.3 to -6.1 ± 0.2 ‰ in two different samples. Grains of prograde tourmaline included in kornerupine and corundum yielded δ11B = -2.1 ± 0.3 to +0.6 ± 0.3 ‰, and the secondary tourmaline replacing kornerupine yielded δ11B = -4.6 ± 0.2 to -3.7 ± 0.2 ‰. Therefore, the isotopic fractionation between kornerupine and tourmaline, △11BTur–Krn (= δ11BTur - δ11BKrn), of the average prograde tourmaline and average host kornerupine is +6.7 ± 1.5 ‰, which is interpreted to indicate isotopic equilibrium at the metamorphic peak on the basis of previous studies of isotope fractionation between tourmaline and minerals of the kornerupine-prismatine series. The δ11B values obtained on prograde tourmaline are between whole rock δ11B of MORB and mantle rocks and of some sedimentary rocks, and are similar to the δ11B of blackwall tourmalines that crystallized during the decompression stage following high-pressure metamorphism. We infer that the syn-metamorphic B-bearing fluid present in the kornerupine-plagioclase-corundum lens is likely sourced from a mixture of sedimentary, mafic and ultramafic lithologies in a subduction setting. The metabasic and meta-ultramafic lenses found in Akarui Point could be interpreted as the remnant of mixing zone of Ediacaran to Cambrian subduction channel.
著者
Fumiko Higashino Tetsuo Kawakami Tatsuro Adachi Masaoki Uno
出版者
Japan Association of Mineralogical Sciences
雑誌
Journal of Mineralogical and Petrological Sciences (ISSN:13456296)
巻号頁・発行日
pp.230131a, (Released:2023-04-21)
被引用文献数
1

This paper reports multiple fluid infiltration events during retrograde metamorphism in the Sør Rondane Mountains, East Antarctica. Pelitic gneisses from southern part of Perlebandet have cordierite-biotite intergrowth rimming garnet, implying that garnet breakdown occurred by fluid infiltration. Using the Raman peak of CO2 in cordierite and Cl-bearing composition in biotite, this study revealed that the cordierite-biotite intergrowth was formed in equilibrium with one-phase CO2-Cl-H2O fluid. The intergrowth texture is cut by thin selvages composed of Cl-bearing biotite, suggesting Cl-bearing fluid infiltration. Since andalusite is exclusively observed in the selvage, near isobaric cooling path is presumed for the pressure-temperature (P-T) path of these post-peak fluid-related reactions. The inconsistence with counter-clockwise P-T path reported from northern Perlebandet is probably due to the granodiorite/leucocratic granite bodies beneath the studied metamorphic rocks. In order to understand the tectonic evolution at the final stage of Gondwana amalgamation, therefore, effect of hidden igneous rocks needs to be taken into consideration.
著者
新井 卓二
出版者
学校法人 山野学苑 山野美容芸術短期大学
雑誌
山野研究紀要 (ISSN:09196323)
巻号頁・発行日
vol.30, pp.19-24, 2022 (Released:2023-03-31)

「健康経営」に取り組む企業は年々増え、2021年度は上場企業の約1/3が取り組む経営戦略となっている。普及に伴い、企業での取り組みにかかわらず、社会への効果も見えるようになってきた。そこで、地方自治体である山形県上山市と宮崎県日向市の取り組みと、地方創生として地方自治体の健康経営向けサービスを支援している林野庁の取り組みを取材し、紹介するものである。具体的には、山形県上山市では「クアオルト」という考え方を、宮崎県日向市ではワーケーションを地方創生として健康経営向けサービスを展開している先進事例が示された。
著者
諸井 克英
出版者
The Japanese Group Dynamics Association
雑誌
実験社会心理学研究 (ISSN:03877973)
巻号頁・発行日
vol.26, no.2, pp.151-161, 1987-02-20 (Released:2010-11-26)
参考文献数
30
被引用文献数
6 4

本研究は, 大学生における孤独感と自己意識傾向の諸側面との関係について検討し, 高校生の結果 (諸井, 1985) との比較によって, 青年期後期における孤独感の様相を明らかにすることを主目的とした。また, S-M傾向を測定する2種の測定を併用し, それぞれの孤独感との関連も含めた妥当性を検討した。被験者は男女大学生396名であった。UCLA孤独感尺度とともに, 自己意識傾向に関する測度として, Rosenberg (1979) の自尊心尺度, Fenigstein et al. (1975) の自己意識尺度, Snyder (1974) のS-M尺度, Lennox & Wolfe (1984) の改訂S-M尺度が用いられた。主要な結果は以下の通りであった。1) 男子の孤独感は, 女子よりも有意に高かった。2) 孤独感は, 男女ともに自尊心およびS-M傾向との間に有意な負の相関, 社会的不安との間に正の相関があり, さらに, 男子では私的自己意識との間に正の相関が認められた。これらの傾向は高校生と同じであった。3) 重回帰分析や判別分析によると, 男子では自尊心, 社会的不安, 私的および公的自己意識, さらにS-M傾向が, 女子では社会的不安および自尊心が, それぞれ有意な孤独感の規定因であった。4) 2つのS-M尺度については, Lennox & Wolfe (1984) の改訂版のほうが尺度構成上の妥当性があるといえるが, 孤独感との関係では両尺度ともに興味ある知見をもたらした。
著者
新田 哲也 坂元 亮一 平原 成浩 松村 吉晃 中村 康大 後藤 雄一
出版者
公益社団法人 日本口腔外科学会
雑誌
日本口腔外科学会雑誌 (ISSN:00215163)
巻号頁・発行日
vol.65, no.9, pp.599-604, 2019-09-20 (Released:2019-11-20)
参考文献数
27
被引用文献数
1 1

The side effects of peroral bisphosphonate may cause mucous membrane disorders and oral exulceration if individuals dissolve the drug inside the oral cavity on oral administration. We experienced two cases in which we strongly suspected mucous ulcurs due to this drug. Finally, the oral exulceration disappeared after providing instructions on correct administration. An 83-year-old woman was referred because of exulceration of the right mandible. She suffered from osteoporosis, thoracic vertebra compression fracture, and dementia, while taking alendronate weekly. The exulceration appeared from the right lower lip to the right mandibular molar gingiva when we absorbed pooled saliva in the right oral cavity when the patient was lying down. We instructed the patient to confirm that the tablet was completely swallowed. The ulcers in the oral cavity completely disappeared 17 days after presentation. A 74-year-old woman with osteoporosis presented because of bleeding and pain in the gingiva of the right mandible. She was taking monthly minodronate while wearing incompatible dentures. Exulceration occurred with peripheral redness ranging from the right buccal mucosa to the right molar gingiva of the mandible and the tongue/floor of her mouth, along with a ventrolateral tongue. We taught her how to swallow minodoronate correctly without dentures, and the ulcers healed 4 weeks later.
著者
西 干機
出版者
日本信頼性学会
雑誌
日本信頼性学会誌 信頼性 (ISSN:09192697)
巻号頁・発行日
vol.32, no.4, pp.200-207, 2010-06-01 (Released:2018-01-31)
参考文献数
16
被引用文献数
2

デザインレビュー(DR)が形作られたのは,1950年代後半と言われている.ここではまず,このようなデザインレビューの生立ちとその進展について標準化の観点から記した.次に,デザインレビューの定義とその運用に関わる代表的な国際規格であるISO(International Organization for Standardization:国際標準化機構)規格及びそのツール規格であるIEC(International Electrotechnical Commission:国際電気標準会議)規格について紹介した.そして,日本でのDRの導入とその展開及び現国際規格の運用上の問題点と今後の展望について述べた.
著者
Tamiko Suzuki-Nishimura Masayoshi Baba Shiori Otani Arisa Yamamoto Yasushi Kodama
出版者
Japanese Pharmacological Society
雑誌
日本薬理学会年会要旨集 (ISSN:24354953)
巻号頁・発行日
pp.PO3-4-11, 2018 (Released:2020-09-10)

The manic depression drug lithium carbonate has many mechanisms of action. As one of these mechanisms is the inhibition of amine release from the end of synapses, we examined the effects of lithium carbonate on the IgE-independent histamine release from rat peritoneal mast cells. In the presence of 0.3 mM CaCl2, at concentrations from 0.3 to 3.0 mM, lithium carbonate inhibited the histamine release induced by bradykinin (BK) (10 μM), substance P (SP) (10 μM) or compound 48/80 (48/80) (1 μg/mL). The histamine release induced by 1 μg/mL of 48/80 was inhibited by lithium carbonate, but that by 5 μg/ml of 48/80 was not. The IgE independent activator GlcNAc-specific Datura stramonium agglutinin (DSA) releases histamine from rat mast cells similar with 48/80, and lithium carbonate also inhibited the histamine release induced by DSA at 100 μg/mL. BK, SP and 48/80 are well-known activators against MRGPR. Mouse MrgprB2 and human MRGPRX2 on mast cells are possible targets of the pseudo-allergic drug reactions involving mast cell activation. Rat peritoneal mast cells have similar MRGPR calcium-dependent and calcium-independent pathways for mast cell activation. Inhibition of BK- or SP-induced histamine release by lithium carbonate did not recover after increasing the extracellular calcium concentration, suggesting that MRGPR in rat mast cells may be a calcium-independent, G-protein dependent receptor. The effects of lithium carbonate suggested that lithium carbonate inhibited downstream of the common signal transduction pathway, following MRGPR activation induced by BK, SP, 48/80 or DSA. The clinical dose of lithium carbonate is from 0.5 to 1 mM, and addiction occurs from 1.8 to 2.5 mM. The inhibitory effects of lithium carbonate on the IgE-independent histamine release were observed at both the clinical and addictive doses in humans, suggesting that lithium carbonate similarly inhibits both histamine release from mast cells and brain amine release from synapses.
著者
野崎 博路
出版者
一般社団法人 日本機械学会
雑誌
日本機械学会論文集 C編 (ISSN:03875024)
巻号頁・発行日
vol.68, no.675, pp.3178-3185, 2002-11-25 (Released:2008-02-26)
参考文献数
2
被引用文献数
1 4

At the first step, I studied the driver model in the drift cornering. At the second step, I studied the technique by which the performance of running in the vehicle at the drift cornering was improved. I have understood the driver is steered by feed back the body slip angle and the body slip angle velocity at the drift cornering. Moreover, I have understood importance in the vehicle movement performance improvement the cornering force characteristic where the maximum cornering force of the tire was exceeded.
著者
窪 徳忠
出版者
日本文化人類学会
雑誌
民族學研究 (ISSN:24240508)
巻号頁・発行日
vol.24, no.1-2, pp.412-437, 1960-03-25 (Released:2018-03-27)

Since the Edo period there has been a prevailing opinion, that the origin of the Japanese Koshin Belief had been derived from Taoism in China, but in recent years Japanese folklorists, with Mr. Kunio YANAGITA as the leader, have come to assert that it was native to Japan. Up to now neither has yet claimed a definite conclusion on this question. The writer thinks that both hypotheses have weaknesses in their methodologies : the former referred only to the literature without reaching into the folk beliefs and customs of the Edo period ; the latter depends only on the results of field work with the presumed ignorance of historical documents. In addition, neither the former nor the latter compare Japanese Koshin Belief in detail with Taoism at all. The writer intends to synthesize the historical records from the Heian period, when Koshin Belief began to appear in Japan, to Meiji Era, with recent field work results, and to compare it with Chinese Taoism and the functions of the Chinese Koshin Belief. He assumed that this method would be the best to determine whether the Koshin Belief has its origin in Japan or not. As the result, Japanese Koshin Belief has come to be judged as the complex of Chinese Taoism, Buddhism including the esoteric form, Shintoism, Shugendo, magical medicine and various Japanese folk beliefs and customs. This study has been published by him under the title of Koshin Belief in Japan. His view-point has been furthermore substantiated by his field research throughout Japan excluding Hokkaido and by his bibliographic survey on this subject. The Japanese folklorist school still insists strongly on the Japanese origin. But he cannot rely on their methodology and is suspicious of how they deal with the data the amount of which in their possession seems not sufficient enough to be handled quantitatively, as well as qualitatively. He can hardly, at present, say whether it was native to Japan, and thinks that he does not need to correct his opinion which Mr. YANAGITA should take into account.
著者
酒井 望 石川 文彦 関 雅史 伊藤 博 諏訪 敏一 宮崎 勝
出版者
日本臨床外科学会
雑誌
日本臨床外科学会雑誌 (ISSN:13452843)
巻号頁・発行日
vol.74, no.7, pp.1899-1903, 2013 (Released:2014-01-25)
参考文献数
18
被引用文献数
2 2

症例は56歳,女性.上腹部痛の精査にて腹腔内腫瘤を指摘された.腹部CTでは腹部大動脈左側,椎体腹側に径3.2cmの辺縁整で内部が不均一に造影される腫瘍を認めた.腹部MRIではCTと同部位に41.4×31.6×25.8mmの辺縁整な腫瘤を認めた.T1強調画像では低信号,T2強調画像,STIR像では均一な等信号で,内部は軽度濃染していた.間葉系腫瘍を疑い手術を施行したところ腫瘍はTreitz靱帯より約2cm肛側の空腸間膜に認められた.腸管,腸間膜血管との連続性はなく腫瘍を摘出した.H.E.染色では,小型類円核を有する腫瘍細胞が地図状,シート状もしくはロゼット状に増殖しており,線維血管性の間質により分画されていた.免疫組織染色では,神経内分泌マーカーはいずれも陽性で,MIB-1標識率は1%以下であった.以上より,NET G1と診断された.腸間膜原発の神経内分泌腫瘍は極めてまれであり,報告する.
著者
廣本 由香
出版者
日本社会学会
雑誌
社会学評論 (ISSN:00215414)
巻号頁・発行日
vol.67, no.3, pp.267-284, 2016 (Released:2017-12-31)
参考文献数
28
被引用文献数
4

本稿の目的は, 福島原発事故を起因とした自主避難をめぐる「不条理な選択」の問題が, 自主避難者の生活を脅かす「広義の被害」 (舩橋1999) になりうることを明らかにすることである. 本稿では, 佐賀県鳥栖市の自主避難者を事例に, 避難の選択過程における経験世界の諸相を‹ゆらぎ›という概念で記述する. ‹ゆらぎ›は, 選択過程の動揺, 葛藤, 不安, 戸惑い, ためらい, わからなさなどが混在する心理的状況や自己認識であり, その変化をさす.政策・法制度的な「加害―被害関係」では把握できない領域を‹ゆらぎ›という概念を用いて記述することで, 原発事故による生活の被害が, 損害賠償制度で認められる領域よりも広範で深刻であるとともに, 長期にわたり生活世界に潜在化・重層化することを示す. すなわち, 生活者の生活の視座から被害を考えたとき, 自主避難の‹ゆらぎ›は生活やそれを下支えする社会関係を揺るがす「広義の被害」となりうることを実証する.今後, 政府の避難指示解除による「『強制避難者』の『自主避難者』化」 (除本2013) が加速する. 社会的制約を受けながら行われた自主避難も, 個人的選択の結果であるとみなす社会規範のもとで自己責任の問題として受け止められてしまう. こうした被害の個人化に陥らないためにも, 「広義の被害」の視座が自主避難者当人の「被害非認識」や「被害の潜在化」による被害の矮小化, 加害者側の「被害放置」を防ぐ手立てとなる.
著者
中根 俊成
出版者
日本神経学会
雑誌
臨床神経学 (ISSN:0009918X)
巻号頁・発行日
vol.59, no.12, pp.783-790, 2019 (Released:2019-12-25)
参考文献数
64

自己免疫性自律神経節障害(autoimmune autonomic ganglionopathy; AAG)は自律神経系が免疫異常の標的となる比較的新しい疾患概念である.本症では抗自律神経節アセチルコリン受容体抗体は病原性自己抗体として病態の鍵となる役割を果たす.本症は広範な自律神経症状以外に自律神経系外の症候(中枢神経系障害,感覚障害,内分泌障害)や併存症(膠原病,腫瘍)を呈することが判ってきた.また,中には消化管運動障害など極部分的な自律神経症状しか呈さないために診断困難である症例が存在する.多くの症例では複合的免疫治療によってコントロール可能となるが,難治例もある.本稿ではAAGとその関連疾患における自己抗体の役割から実臨床に関連する話題までを総説する.
著者
光田 尚代 高木 綾一 鈴木 俊明
出版者
関西理学療法学会
雑誌
関西理学療法 (ISSN:13469606)
巻号頁・発行日
vol.12, pp.35-39, 2012 (Released:2012-12-27)
参考文献数
13
被引用文献数
2

Quadriceps setting is widely used as a muscle strengthening exercise for the quadriceps femoris muscle. It is frequently employed from the early post-operative stage for patients receiving knee joint replacement surgery, such as total knee arthroplasty, at our hospital. Quadriceps setting is frequently performed with ankle joint dorsiflexion in the supine position. Patients performing quadriceps setting often say “I can’t understand where to flex the muscle in the leg.” Therefore, we analyzed this exercise in patients receiving knee joint treatments such as total knee replacement surgery. The patients were explained in a simple and easy-to-understand manner the correct way of performing quadriceps setting for efficient restoration of the quadriceps femoris muscle activity. In addition, we devised a quadriceps setting exercise involving knee extension and ankle dorsiflexion with the heel pressed down, encouraging simultaneous contraction of the quadriceps and gluteus maximus muscles, and analyzed the effectiveness of this exercise on quadriceps femoris muscle activity.
著者
Takaomi Kasuga Asako Sato Tetsuya Babazono
出版者
Society of Tokyo Women's Medical University
雑誌
Tokyo Women's Medical University Journal (ISSN:24326186)
巻号頁・発行日
pp.2022015, (Released:2023-04-27)
参考文献数
30

Background: Aortic valve calcification (AVC) has a strong association with cardiovascular outcomes in patients with type 2 diabetics (T2D). The objective of this study was to determine the prevalence and risk factors for AVC in Japanese T2D.Methods: We conducted a cross-sectional study of 193 consecutive T2D with estimated glomerular filtration rate (eGFR) ≥ 60 mL/min/1.73 m2 and without overt heart disease (110 men, mean age 61 years). AVC was determined as bright echoes > 1 mm on at least one cusp of the aortic valve by echocardiography.Results: Eighty-two (42%) diabetic patients had AVC, 9 patients had aortic valve stenosis, and 25 had regurgitation. Patients with AVC were older (67 vs. 55 years), with longer diabetic duration (15 vs. 11 years), lower HbA1c (9.1 vs. 10.0%), higher presence of diabetic retinopathy (66 vs. 47%), lower BMI (24 vs. 26 kg/m2), and lower eGFR (82.1 vs. 90.4 mL/min/1.73 m2) (p < 0.01) than patients without AVC. By logistic regression analysis, older age (p < 0.001) and presence of diabetic retinopathy (p < 0.05) were independent risk factors for AVC in T2D.Conclusions: The prevalence of AVC was 42% in Japanese T2D. Diabetic retinopathy associates with presence of AVC.