著者
野川 茂
出版者
一般社団法人 日本血栓止血学会
雑誌
日本血栓止血学会誌 (ISSN:09157441)
巻号頁・発行日
vol.27, no.1, pp.18-28, 2016 (Released:2016-02-26)
参考文献数
42
被引用文献数
6 8

要約:トルーソー症候群は「悪性腫瘍に合併する凝固能亢進状態とそれに伴う遊走性血栓性静脈炎」をさすが,脳梗塞の発症を機に初めて悪性腫瘍が発見されることも少なくない.このため,本邦では「悪性腫瘍に合併するDIC に伴う血栓症および非細菌性血栓性心内膜炎(NBTE)に起因する全身性(とくに脳)塞栓症」として理解されつつある.原因となる悪性腫瘍は,白血病を除けば,肺癌,膵癌,胃癌,卵巣癌(ムチン産生腫瘍)などの腺癌が圧倒的に多い.頭部MRI では多発性塞栓症を呈することが多く,約半数にNBTE が認められるが,経胸壁心エコーでの検出率は低く,経食道心エコーが診断に有用である.また,CA125 やCA19-9 などの高分子ムチンが,腫瘍マーカーあるいは塞栓形成物質として注目されている.治療では,ワルファリンの効果は不確実とされ,出血がコントロールされていれば,未分画ヘパリン静注やヘパリンカルシウム皮下注が用いられる.
著者
澤田 真人
出版者
口腔病学会
雑誌
口腔病学会雑誌 (ISSN:03009149)
巻号頁・発行日
vol.71and72, no.4-1, pp.28-41, 2005-03-31 (Released:2010-10-08)
参考文献数
33
被引用文献数
7 12

The threshold levels of taste perception on the right and left side of the tip, root of tongue and soft palate in 60 healthy volunteers were measured by means of an electrogustometry test and a filter-paper disk taste test to confirm the following hypotheses : 1) the threshold on the tip of the tongue was lower than those of the root of the tongue and soft palate, 2) there was a different threshold level between sweet, salty, sour and bitter tastes on the tip of the tongue, 3) some personal properties influenced the person's threshold. Measured threshold levels were compared between these six locations with multiple comparisons. Factors influencing the threshold level on the tip of the tongue, thereafter, were investigated using multivariate logistic regression models. Those factors included sex, age, serological, psychological and behavioral factors. As a result, the thresholds levels on the tip of the tongue were significantly lower than the root of the tongue and soft palate. The thresholds for sweet and bitter taste on the tip of the tongue were also lower than those for salty and sour taste. Increase of age, male, serological increase of zinc and usual alcohol drinking were identified as factors of increase for several thresholds, and increase of anxiety was identified as a factor of decrease for two thresholds of four tastes (sweet, salty, sour and bitter) on the tip of the tongue in the logistic regression models. Increase of depression, mouth breathing, habitual tonus of the tongue and smoking did not appear to be influential factors.
著者
宇於崎 勝也 浅香 勝輔
出版者
公益社団法人 日本都市計画学会
雑誌
都市計画論文集 (ISSN:09160647)
巻号頁・発行日
vol.31, pp.733-738, 1996-10-25 (Released:2018-06-20)
参考文献数
4

THE AIM OF THIS STUDY IS TO MAKE CLEAR OF THE COURSE OF THE CREMATORIUM IMPROVEMENT IN THE CITY. THE CREMATORIUM IS VERY IMPORTANT AND ONE OF THE PUBLIC FACILITIES. AT FAST, WE ANALYZE THE PRESENT CONDITION OF THE CREMATORIA, WHICH ARE TWELVE DESIGNATED CITIES OF GOVERNMENT. THEN, WE SEARCH FOR SOME URBAN PROBLEM AND THEMES ABOUT THE CREMATORIA IN FOUR CITIES. NEXT, WE EXAMINE TREND OF THE CREMATORIUM IN INCREASING AND AGING OF POPULATION IN JAPAN. AT LAST, WE PROPOSE SOME CRITICAL MIND AND PROBLEM OF THE CREMATORIUM.
著者
NAKAMURA Kenji
出版者
Meteorological Society of Japan
雑誌
気象集誌. 第2輯 (ISSN:00261165)
巻号頁・発行日
pp.2021-035, (Released:2021-03-12)
被引用文献数
11

The Tropical Rainfall Measuring Mission (TRMM) satellite was launched in 1997 and the observations continued for more than 17 years. The features of TRMM observation were as follows: (a) it followed a non-sun synchronized orbit that enabled diurnal variation of precipitation to be investigated, (b) it carried a precipitation radar and microwave and infrared radiometers, along with two instruments of opportunity in the form of a lighting sensor and a radiation budget sensor, and (c) it worked as a standard reference for precipitation measurements for other spaceborne microwave radiometers, which enabled global rain maps to be developed. For science, TRMM provided precise and accurate rain distributions over tropical and subtropical regions. The rainfall results are primarily important for the study of the precipitation climatologies, while the three-dimensional images of precipitation systems enabled the study of the global characteristics of precipitation systems. Technologically, the spaceborne rain radar onboard TRMM demonstrated the effectiveness of radars in space, while the combination with other rain observation instruments showed its effectiveness as a calibration source. Multi-satellite rain maps in which TRMM was the reference standard have been developed, and they became prototypes of the multi-satellite Earth observation systems. Based on the great success of TRMM, the Global Precipitation Measurement (GPM) was designed to expand TRMM's coverage to higher latitudes. The core satellite of GPM is equipped with a dual frequency precipitation radar (DPR) and a microwave radiometer. DPR consists of a Ku-band radar (KuPR) and a Ka-band radar (KaPR) and has a capability to discriminate solid from liquid precipitation. The period of the precipitation measurement with spaceborne radars extended to more than 23 years which may make it possible to detect the change of precipitation climatology related to change in the global environment. While TRMM's and GPM's accomplishments are very broad, this paper tries to highlight Japan's contributions to the science of these missions.
著者
YAMAJI Moeka KUBOTA Takuji YAMAMOTO Munehisa K.
出版者
Meteorological Society of Japan
雑誌
気象集誌. 第2輯 (ISSN:00261165)
巻号頁・発行日
pp.2021-033, (Released:2021-02-17)
被引用文献数
8

Reliability information of satellite precipitation products is required for various applications. This study describes and evaluates a reliability flag of the Global Satellite Mapping of Precipitation Near-Real-Time precipitation product (GSMaP_NRT). This flag was developed to characterize the reliability of GSMaP_NRT data simply and qualitatively by considering its algorithm characteristics. The reliability at each pixel is represented by any one of ten levels (10 being the best and 1 the worst) by considering three major factors: 1) “surface type reliability”—which takes into account that estimation of rainfall using passive microwave sensors is better over the oceans than over land and coastal areas; 2) “low-temperature reliability”—which takes into account the lower reliability due to surface snow cover in low-temperature conditions; and 3) “Moving Vector with Kalman Filter (MVK) propagation reliability”—which means that the reliability gets worse with the increase in time since the last overpass of the passive microwave sensor. To evaluate the utility of the reliability flag, statistical indices are calculated for each reliability level using gauge-calibrated ground radar data around Japan. It is found that the reliability flag represents the differences in GSMaP accuracy: the accuracy worsens as the reliability decreases. The GSMaP errors exhibit seasonal changes that are well represented by the ten levels of the reliability flag, indicating that the reliability flag can be used to catch seasonal variations in GSMaP accuracy due to changes in environmental factors. This study also raises the possibility of improving the reliability flag by using information related to heavy orographic rainfall. It is shown how the error features of heavy orographic rainfall differ from those of the total rainfall, and it is suggested that heavy orographic rainfall information can be utilized to further improve the reliability flag.
著者
CHENG Chiu Tung SUZUKI Kentaroh
出版者
Meteorological Society of Japan
雑誌
気象集誌. 第2輯 (ISSN:00261165)
巻号頁・発行日
pp.2021-031, (Released:2021-02-18)

The transport and removal processes of aerosol particles, as well as their potential impacts on clouds and climate, are strongly dependent on the particle sizes. Recent advances in computational capabilities enable us to develop sectional aerosol schemes for general circulation models and chemical transport models. The sectional aerosol modeling framework provides a capacity to explicitly simulate the variations in size distributions due to microphysical processes such as nucleation and coagulation, based on the mechanisms suggested from laboratory studies and field observations. Here, we develop a two-moment sectional aerosol scheme for Spectral Radiation-Transport Model for Aerosol Species (SPRINTARS-bin) for use in NICAM (Nonhydrostatic ICosahedral Atmospheric Model) as an alternative to the original mass-based (single-moment) SPRINTARS-orig aerosol module. NICAM-SPRINTARS is a seamless multiscale model that has been used for regional-to-global simulations of different resolutions based on the same model framework. In this study, we performed global simulations with NICAM-SPRINTARS-bin at typical climate model resolution (Δx ∼ 230 km) with nudging to a meteorological re-analysis. We compared our results with equivalent simulations for the original model (NICAM-SPRINTARS-orig) and observations including 500 nm aerosol optical depth and 440-870 nm Angstrom Exponent in AErosol RObotic NETwork (AERONET) measurements, particle number concentrations measured at Global Atmospheric Watch (GAW) sites and size-resolved number concentrations measured at European Supersites for Atmospheric Aerosol Research (EUSAAR) and German Ultrafine Aerosol Network (GUAN) sites. We found that compared to NICAM-SPRINTARS-orig, NICAM-SPRINTARS-bin demonstrates the long-range transport of ultra-fine particles to high latitudes and predicts higher Angstrom Exponent and total number concentrations that better agrees with observations. The latter underscores the importance of resolving the microphysical processes that determine concentrations of ultra-fine aerosol particles and explicitly represent size-dependent deposition in predicting these properties. However, number concentrations of coarse particles are still underestimated by both the original mass-based and the new microphysical schemes. Further efforts are needed to understand the reasons for the differences with the observed size distributions, including testing different emission and secondary organic aerosol production schemes, incorporating inter-species coagulation and black carbon aging, as well as performing simulations with higher spatial resolutions.
著者
吉岡 敏和 苅谷 愛彦 七山 太 岡田 篤正 竹村 恵二
出版者
公益社団法人 日本地震学会
雑誌
地震 第2輯 (ISSN:00371114)
巻号頁・発行日
vol.51, no.1, pp.83-97, 1998-07-03 (Released:2010-03-11)
参考文献数
19
被引用文献数
1 1

The Hanaore fault is a right-lateral strike-slip active fault about 48km long in central Japan. We carried out comprehensive surveys including trench excavations on the Hanaore fault to evaluate the seismic risk of the highly populated area, such as Kyoto City, along this fault. Three trenches were excavated on the fault. On the exposure of the northernmost Tochudani trench, a fault cutting fluvial sediments and humic soil beds appeared. The youngest age of displaced sediments is 460±60 14C yBP, and the sediments covering the fault is 360±60 14C yBP. This faulting event may be correlated to the historical 1662 Kambun earthquake. The southernmost Imadegawa trench was excavated on the road in the urban area of Kyoto City. A thrust fault cutting humic soil with pottery fragments of the Late Jomon period (about 3, 500 years ago) was observed on the trench walls. It was difficult to detect the age of the last faulting event due to lack of younger sediments and artificial modifications of the surficial materials. However, the southern part of the fault might not move during the 1662 earthquake because the damage in this area was much less than in along the northern and middle part of the fault. The historical documents recorded that the land along the Mikata fault which is located at the north of the Hanaore fault was uplifted, and the land along the western shoreline of Lake Biwa where is the east of the Hanaore fault was subsided during the 1662 earthquake. This means that the 1662 earthquake might be a multi-segment event caused by these three faults, the Mikata fault, the northern part of the Hanaore fault, and the faults along the western shoreline of Lake Biwa.
著者
杉山 和明
出版者
The Human Geographical Society of Japan
雑誌
人文地理 (ISSN:00187216)
巻号頁・発行日
vol.51, no.4, pp.396-409, 1999-08-28 (Released:2009-04-28)
参考文献数
59
被引用文献数
5 2

In recent years, there has been much debate over the social production of space and the relationship between social subject and space. The author, emphasizing the social structural context, contributes to this debate by identifying social space focused on one district. This paper seeks to reveal the significant relationship in which society and space are reconstructed in the late modern era, considering the differences between subjective space and objective space, mass behavior during weekend nights, and the factors influencing the mechanism of perception. To put it concretely, the purpose of this paper is to explain how youths, between the ages of 15 and 29, use the space and act in the night amusement quarter applying the concept of social space, and to examine the experiences of this generation using the ethnographical method.A case study was carried out in the EKIMAE district, the redeveloped area in front of Toyama station, Toyama City. EKIMAE is a commonly used name for the space. Social space refers to subjective social space expressed as a mental map depicted in the youths' own way. On the other hand, objective social space is the space bounded by the regulator of public space, the Toyama Police Department, which is a police patrolling area defined by their own territorial perception in order to monitor and control the populace. Neither space, objective and subjective, is an official administrative district.The remarkable result of various examinations of these spaces is that NANPA spot, a place where girl or boy hunting are conducted, is equivalent to subjective social space and plays an important role for the youth to maintain their identity. Examining the way in which commodities were selected by the youth in the questionnaire, it was demonstrated that various commodities are obstacles to their entry. Furthermore, when they participate in the space as an actor or observer, space functions as theater in a high consumption society. As such, the space where youths encounter one another is constructed as subjective social space and they therefore tend to feel their perceived territory as home.This analysis assists us in understanding the quality of late modern places and how subject and place become inextricably intertwined in the context of social structure.
著者
増田 淳
出版者
公益社団法人 応用物理学会
雑誌
応用物理 (ISSN:03698009)
巻号頁・発行日
vol.90, no.6, pp.339-345, 2021-06-05 (Released:2021-06-05)
参考文献数
44

屋外で曝露(ばくろ)される太陽電池モジュールにはさまざまな負荷が複合して与えられ,その結果,発電性能低下が生じる.劣化現象は複雑であるものの,劣化要因は遮光,集電能力低下,光起電力低下の3つに大別可能である.本稿では,さまざまな太陽電池モジュールの劣化現象をこれら3つの劣化要因に整理して紹介する.とりわけ,電圧誘起劣化については,最新の研究成果も含めて詳細に説明する.また,さまざまな負荷のうち,屋外で使用する太陽電池にとって避けることのできない紫外光照射が劣化現象に及ぼす影響についても紹介する.
著者
渡辺 達朗
出版者
日本マーケティング学会
雑誌
マーケティングジャーナル (ISSN:03897265)
巻号頁・発行日
vol.38, no.3, pp.17-36, 2019-01-17 (Released:2019-01-17)
参考文献数
72
被引用文献数
1

イギリスの都市政策では多様性の維持に加えて,1990年代後半以降は持続可能性が,基本となる考え方として位置づけられてきた。それらに基づいて,一方で開発許可を軸にしたプラニングシステムによって大規模ショッピングセンターをはじめとするさまざまな開発を規制してきた。そこでは,タウンセンターの「活力と存続」,あるいはタウンセンターファーストの考え方を前提にした逐次的アプローチというコンセプトが受け継がれている。他方,都市再生の側面では,タウンセンターにおける小売,サービス,エンターテイメント,そして住宅などを含む大規模再開発と,インナーシティにおける近隣街区リニューアルが並行して実施されてきた。本稿では,以上のような経緯について思想,政策,取組みという3つの次元から確認する。その上で,都市計画による郊外開発規制,将来ビジョンとしてのコンパクトシティ,タウンセンターやハイストリートにおける多様性と同質化,という3つの論点から日本への示唆を探る。
著者
土屋 昭夫 相澤 直孝 佐藤 邦広 高橋 姿
出版者
日本口腔・咽頭科学会
雑誌
口腔・咽頭科 (ISSN:09175105)
巻号頁・発行日
vol.25, no.2, pp.173-177, 2012 (Released:2012-08-25)
参考文献数
20

線維素性唾液管炎は, 唾液腺導管内に線維素塊が形成されて導管の閉塞をきたし, 反復性に唾液腺腫脹をきたす疾患である. 腫脹時に唾液腺を圧迫すると, 導管から多数の好酸球を含む線維素塊の排出を認める. アレルギー性疾患を合併することが多く, そのため発症の原因としてアレルギーの関与が考えられている.今回われわれは, 反復する耳下部腫脹を主訴に当科を受診し, 線維素性唾液管炎と診断された3例を経験したので報告する. 3例ともにアレルギー疾患の合併があり, 2例ではステノン管からの排出物に好酸球を認めた. 全例で抗アレルギー剤の効果を認めたが, 1例を除き症状は残存しており, ステロイド治療の追加を検討している.
著者
山鹿 誠次
出版者
The Association of Japanese Geographers
雑誌
地理学評論 (ISSN:00167444)
巻号頁・発行日
vol.32, no.1, pp.35-41, 1959-01-01 (Released:2008-12-24)
参考文献数
3
被引用文献数
1

The writer has studied the process by which the city functions, developing towards the urban fringes, incited the urbanization of suburbs. Special hospitals for the patients of such diseases as tuburculosis, mental disease and infectious diseases seek their sites in the suburbs of the metroplis, because there they can get capacious grounds, quiet environment and fresh air. When we see the distribution of the special hospitals in Tokyo, we find that most of the newly established hospitals are situated in the urban fringe, and some of the older ones built in the inner region, have removed centrifugally to the outshirts. Kiyose town is in the western suburbs of Tokyo, and on the Musashino Upland. It was formerly a farm-village, , but since 1331 many tuburculosis hospitals have been established in the pine forests of the south-western area of this town, and so Kiyose has become one of the largest hospital quarters in Japan, having 14 hospitals, 4, 821 beds, and 25% of its whole ares is covered by hospitals. Consequently, the population increased rapidly and the shopping street developed between the, hospital quarters and the railway station. Moreover many residential houses were recently built, and this town has also grown into one of the residential districts of Tokyo. Through the study of Kiyose and some other hospital quarters in Tokyo, the writer has come to the conclusion that there are some grades in the relations between the special hospitals and the urbanization in the metropolis. The grades are as follows: (1) Special hospitals were first established in the innermost region of the metropolis, but with the development of the metropolis, they moved to the outer regions, or were turned into general hospitals. (2) In the region next to the former innermost region of the metropolis, the hospitals which were established in the days when the region were the suburbs are now in the residential districts which have developed since their establishment. (3) In the next region, urbanization is in advance, and there the hospital quarter and the residential district are contiguous to each other. (4) In the outermost region of the metropolis, hospitals are situated apart from other establishments, and the residential district has not advanced into this region yet. Kiyose belongs to the third grade.
著者
Marcos Fernando Basso Karoline Estefani Duarte Thais Ribeiro Santiago Wagner Rodrigo de Souza Bruno de Oliveira Garcia Bárbara Dias Brito da Cunha Adilson Kenji Kobayashi Hugo Bruno Correa Molinari
出版者
Japanese Society for Plant Biotechnology
雑誌
Plant Biotechnology (ISSN:13424580)
巻号頁・発行日
pp.21.0407a, (Released:2021-06-12)
参考文献数
64
被引用文献数
8

The CRISPR/Cas9 system has been used for genome editing in several organisms, including higher plants. This system induces site-specific mutations in the genome based on the nucleotide sequence of engineered guide RNAs. The complex genomes of C4 grasses makes genome editing a challenge in key grass crops like maize (Zea mays), sorghum (Sorghum bicolor), Brachiaria spp., switchgrass (Panicum virgatum), and sugarcane (Saccharum spp.). Setaria viridis is a diploid C4 grass widely used as a model for these C4 crop plants. Here, an optimized CRISPR/Cas9 binary vector that exploits the non-homologous end joining (NHEJ) system was used to knockout a green fluorescent protein (gfp) transgene in S. viridis accession A10.1. Transformation of embryogenic callus by A. tumefaciens generated ten glufosinate-ammonium resistant transgenic events. In the T0 generation, 60% of the events were biallelic mutants in the gfp transgene with no detectable accumulation of GFP protein and without insertions or deletions in predicted off-target sites. The gfp mutations generated by CRISPR/Cas9 were stable and displayed Mendelian segregation in the T1 generation. Altogether, the system described here is a highly efficient genome editing system for S. viridis, an important model plant for functional genomics studies in C4 grasses. Also, this system is a potential tool for improvement of agronomic traits in C4 crop plants with complex genomes.