著者

関口 慶二

出版者

公益社団法人 日本薬学会

雑誌

YAKUGAKU ZASSHI (ISSN:00316903)

巻号頁・発行日

vol.81, no.5, pp.669-674, 1961-05-25 (Released:2010-02-19)

参考文献数

9

被引用文献数

8

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Thermal analysis was carried out on 26 kinds of binary systems, having caffeine as one component and various carboxylic acids as the other. Molecular compounds were formed by caffeine with o-, m-, and p-hydroxybenzoic acid, gallic acid, m-me-thoxybenzoic acid, m-nitrobenzoic acid, o-, m-, and p-aminobenzoic acid, phenylacetic acid, malonic acid, oxalic acid dihydrate, and maleie acid. Caffeine did not form a molecular compound with benzoic and phthalic acids. Comparison of the result of thermal analysis and the report of Higuchi and others regarding caffeine complex in aqueous solution suggested that there is some difference in the behavior of caffeine between anhydrous state and in aqueous solution.

著者

Ryota Sakurai Hisashi Kawai Hideyo Yoshida Taro Fukaya Hiroyuki Suzuki Hunkyung Kim Hirohiko Hirano Kazushige Ihara Shuichi Obuchi Yoshinori Fujiwara

出版者

日本疫学会

雑誌

Journal of Epidemiology (ISSN:09175040)

巻号頁・発行日

pp.JE20150017, (Released:2016-02-20)

参考文献数

28

被引用文献数

20

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Background: The health benefits of bicycling in older adults with mobility limitation (ML) are unclear. We investigated ML and functional capacity of older cyclists by evaluating their instrumental activities of daily living (IADL), intellectual activity, and social function.Methods: On the basis of interviews, 614 community-dwelling older adults (after excluding 63 participants who never cycled) were classified as cyclists with ML, cyclists without ML, non-cyclists with ML (who ceased bicycling due to physical difficulties), or non-cyclists without ML (who ceased bicycling for other reasons). A cyclist was defined as a person who cycled at least a few times per month, and ML was defined as difficulty walking 1 km or climbing stairs without using a handrail. Functional capacity and physical ability were evaluated by standardized tests.Results: Regular cycling was documented in 399 participants, and 74 of them (18.5%) had ML; among non-cyclists, 49 had ML, and 166 did not. Logistic regression analysis for evaluating the relationship between bicycling and functional capacity revealed that non-cyclists with ML were more likely to have reduced IADL and social function compared to cyclists with ML. However, logistic regression analysis also revealed that the risk of bicycle-related falls was significantly associated with ML among older cyclists.Conclusions: The ability and opportunity to bicycle may prevent reduced IADL and social function in older adults with ML, although older adults with ML have a higher risk of falls during bicycling. It is important to develop a safe environment for bicycling for older adults.

著者

伊藤 武彦 田原 俊司 朴 媛淑

出版者

一般社団法人 日本教育心理学会

雑誌

教育心理学研究 (ISSN:00215015)

巻号頁・発行日

vol.39, no.1, pp.75-84, 1991-03-30 (Released:2013-02-19)

参考文献数

24

被引用文献数

1 2 3

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In a Japanese agent-patient-action type sentence, an agent is marked by the nominative particle GA and a patient is marked by the accusative particle 0. The aim of the present study was to compare the cue strength of 0 with that of GA in sentence comprehension of agent-patient relations and to find their developmental process. Because 0 is semantically simpler than GA, it was hypothesized that (1) the cue strength of 0 was stronger than that of GA and (2) the acquisition period of the former particle was earlier than that of the latter in Japanese children. Eighty Japanese native speakers of 5, 6, 7, 9, 11, 13, 15 years old and adults were instructed to listen to simple sentences and to judge which noun was the agent in an act out method by using miniature animals and objects. Stimulus sentences consisted of 27 sentence types composed of word order×particle×noun animacy combinations. The results were compared with Ito and Tahara (1986). The hypotheses were both verified.

著者

加藤 秀章 高橋 和明 中村 誠 池内 寛和 平野 敦之 安倍 夏生 新井 雅裕 三代 俊治

出版者

一般社団法人 日本肝臓学会

雑誌

肝臓 (ISSN:04514203)

巻号頁・発行日

vol.52, no.8, pp.524-527, 2011 (Released:2011-08-29)

参考文献数

5

被引用文献数

2 3

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Two 71-year-old males (Case 1 and 2) with liver dysfunction were admitted to our hospital and diagnosed with acute hepatitis E due to detection of hepatitis E virus (HEV) RNA or IgM class anti-HEV in their sera. Since they ate the same rare wild boar meat at the same ritual, the boar meat was considered to be the infection source. Phylogenetic analysis showed that HEV strain identified in Case 1 segregated to a cluster of "Aichi/Shizuoka Strains". It seems that the "Aichi/Shizuoka Strain", an atypical genotype 4 strain compared to those found in other part of Japan, is prevailing within this small geographic area.

著者

熊代 泉 若松 八郎 小町谷 吉興 山田 吉孝 野田 一郎 館川 直樹

出版者

社団法人 有機合成化学協会

雑誌

有機合成化学協会誌 (ISSN:00379980)

巻号頁・発行日

vol.27, no.3, pp.202-206, 1969-03-01 (Released:2009-11-13)

著者

星野 安咨

出版者

日本遺伝学会

雑誌

遺伝学雑誌 (ISSN:0021504X)

巻号頁・発行日

vol.16, no.4, pp.155-163, 1940 (Released:2007-04-04)

参考文献数

4

被引用文献数

3

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In this report two more rare pattern types: aulica (Fig. 1-a, b) and gutta (new name proposed by Prof. T. Komai) (Fig. 1-f, g, h) are dealt with. Both of these are due to the factors (PAu=factor for aulica, PG=factor for gutta) belonging to the same allelomorphic series as conspicua, transversifascia, spectabilis, axyridis, forficula and succinea and behave as dominants to succinea.The heterozygote of axyridis and aulica (PAPAu) (Fig. 1-c) and the heterozygote of forficula and aulica (PFPAu) (Fig. 1-d) can be distinguished as such from homozygotes. The heterozygote of transversifascia and aulica (PTPAu) may be distinguished from transversifascia in that the spot has a concavity on the antero-median side (Fig. 1-e), though in some cases the heterozygote of transversifascia and aulica shows the same appenrance as transversifascia. The distinction between the heterozygote of gutta and axyridis (PGPA) and the heterozygote of conspicus and axridis (PCPA) and that between the heterozygote of gutta and forficula (PGPF) and the heterozygote of conspicua and forficula (PCPF) can often made by the fact that the spot is provided with an accessory speck on its antero-median corner, though the speck may be missing in some cases (see Report II, Fig. 1-l, m and Report III, Fig. 1-e). The heterozygote of conspicua and aulica (PCPAu), the heterozygote of conspicua and gutta (PCPG), the heterozygote of gutta and spectabilis (PGPS), the heterozygote of gutta and transversifascia (PGPT) and the heterozygote of gutta and aulica (PGPAu) can not be distinguished from conspicua; the heterozygote of spectabilis and aulica (PSPAu) may shows the same appearance as spectabilis.

著者

Mario DOLERA Luca MALFASSI Cristina BIANCHI Nancy CARRARA Laura CORBETTA Sara FINESSO Silvia MARCARINI Giovanni MAZZA Simone PAVESI Massimo SALA

出版者

公益社団法人 日本獣医学会

雑誌

Journal of Veterinary Medical Science (ISSN:09167250)

巻号頁・発行日

pp.15-0421, (Released:2016-02-28)

被引用文献数

4

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The aim of this work was to present a novel minimally invasive surgical stabilization technique for canine atlanto-occipital dislocation and to report the associated magnetic resonance imaging (MRI) findings. All 5 dogs in this case series underwent 1.5 T MRI of the head and neck and 3 underwent both MRI and computed tomography (CT). Atlanto-occipital dislocations were diagnosed based on the increased joint space between the occipital condyles and the atlas on MRI. Surgery was performed immediately with a never previously described fixation technique based on an external ligature. The stabilization was performed via 4 holes drilled in the zygomatic processes and in the atlas wings on each side. A nylon monofilament of 1 mm diameter was inserted in the 4 holes and an O-shaped ligature was carried out externally to the skin through the ipsilateral zygomatic arch. Ligatures were removed within 2 months. At the postsurgical follow-up examination, 14 days after surgery, all dogs were found to be ambulatory. Atlanto-occipital stability was assessed by clinical examination with an average of 24 months of follow-up. The positive outcomes in this case series suggest that atlanto-occipital dislocation may be surgically treated with this novel technique, irrespective of the severity of the clinical presentation and associated lesions observed on MRI.

著者

下島 昌幸 福士 秀悦 谷 英樹 吉河 智城 森川 茂 西條 政幸

出版者

日本ウイルス学会

雑誌

ウイルス (ISSN:00426857)

巻号頁・発行日

vol.63, no.1, pp.7-12, 2013-06-25 (Released:2014-04-26)

参考文献数

25

被引用文献数

1 11 1

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重症熱性血小板減少症候群は新種のブニヤウイルス(重症熱性血小板減少症候群ウイルス)による感染症で,致死率は約12%,主にマダニによって媒介される.これまで中国でのみ報告があったが,国内で昨年秋に亡くなられた方が本疾患に罹患していたことが判明した.後方視的調査の結果,これまでに計8名の方が罹患し内5名の方が亡くなられていたことが明らかとなった.いずれも国内で感染しており,病原体は以前から国内に存在していたと考えられる.

著者

小松崎 俊彦 岩田 佳雄

出版者

一般社団法人 日本機械学会

雑誌

日本機械学会論文集C編 (ISSN:18848354)

巻号頁・発行日

vol.78, no.786, pp.420-430, 2012 (Released:2012-02-25)

参考文献数

10

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In this study, a virtual sound production system is developed where the difference frequency component appears as the secondary audible sound at a point of interference locally by the nonlinear interaction of two independently radiated ultrasounds while they travel directionally and intersect each other. The design of high-directive ultrasonic radiator, followed by the investigation of virtual sound production performance has been done theoretically as well as experimentally. It is known from these investigations that the fairly local sound reproduction in free space is possible, yet the sound pressure level of the secondary field is small. The results have also shown that the generated virtual sound area is dependent on both the difference frequency and the intersection angle of two carrier waves emitted by two sound sources.

著者

佐藤 教男

出版者

社団法人 日本金属学会

雑誌

日本金属学会会報 (ISSN:00214426)

巻号頁・発行日

vol.12, no.10, pp.661-669, 1973-10-20 (Released:2011-08-10)

参考文献数

17

被引用文献数

1 1

著者

北村 正樹

出版者

耳鼻咽喉科展望会

雑誌

耳鼻咽喉科展望 (ISSN:03869687)

巻号頁・発行日

vol.53, no.1, pp.44-46, 2010 (Released:2011-02-15)

参考文献数

4

著者

湯木 正史 鈴木 清美 杉本 典子 樋口 貴志 鈴木 秀典 石川 勝行

出版者

公益社団法人 日本獣医師会

雑誌

日本獣医師会雑誌 (ISSN:04466454)

巻号頁・発行日

vol.57, no.11, pp.721-724, 2004-11-20 (Released:2011-06-17)

参考文献数

11

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免疫介在性溶血性貧血 (Immune-mediated hemolytic anemia: IMHA) と診断した犬2例に対し, プレドニゾロン, シクロスポリン, アザチオプリン, ヒト免疫グロブリン製剤, 輸血などによる治療を行ったが, 貧血の改善が得られなかった. そこでシクロスポリンの10~100倍の免疫抑制作用を持つとされるタクロリムス (FK506) を併用したところ, 1例では貧血の著明な改善が, 他の1例ではPCVの維持が認められた.

著者

細矢 治夫

出版者

公益社団法人 日本化学会・情報化学部会

雑誌

日本化学会情報化学部会誌 (ISSN:09133747)

巻号頁・発行日

vol.21, no.1, pp.2-2, 2003 (Released:2003-01-30)

参考文献数

6

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.

著者

小泉 武栄

出版者

公益社団法人 東京地学協会

雑誌

地学雑誌 (ISSN:0022135X)

巻号頁・発行日

vol.120, no.5, pp.761-774, 2011-10-25 (Released:2012-01-17)

参考文献数

20

被引用文献数

4 6 6

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A geopark involves not only a geological heritage but also geographical and ecological elements. Therefore, subjects related to geotourism are not only landforms and geology, but also ecosystems, including vegetation and animal communities, and human landscapes, such as terraced rice paddies and grasslands created by human activity. Because geotourism covers a broad range of elements, from geo- and ecosystems to human activities, it is expected that the further development of related activities will be supported and approved by an increasing number of people. In this manuscript, I introduce some examples of geo-ecotourism as a special type of geotourism, including: vegetation at the summit area of Mount Hakusan, vegetation in a landslide scar on Mount Bandaisan, and the habitat of Dicentra peregrine on Mount Yatsugatake. These were all very popular with the participants of excursions I conducted. Geotours also promote regional development because they benefit residents economically by employing local workers and travel-related businesses, and encourage consumption of local services and products by visitors. A pressing issue concerning geotourism in Japan is the development of human resources such as tour guides. A geotour needs an excellent guide with a riveting interpretation. There are, however, few of such guides and there is a need to rapidly foster more. As a model for fostering guides, I introduce my “Intensive course on the natural history of mountains,” which interprets the natural history of mountains based on geo-ecology. In the long term, however, it is necessary to introduce natural history education into the school system and improve the quality of nature programs broadcast on TV. Many participants of geotours are middle aged and older, and tend to be energetic and slow to age. This may be because the tour participants are required to do physical activity and to use their common sense. Based on this perspective, a geopark approach must gain in importance within social and lifelong education.

著者

三橋 邦宏 上牟田 千尋 岡 富士男

出版者

公益社団法人 日本マリンエンジニアリング学会

雑誌

日本舶用機関学会誌 (ISSN:03883051)

巻号頁・発行日

vol.24, no.10, pp.465a-468, 1989-10-01 (Released:2010-05-31)

参考文献数

4

著者

池谷 真梨子 柳沢 幸江

出版者

一般社団法人 日本家政学会

雑誌

日本家政学会誌 (ISSN:09135227)

巻号頁・発行日

vol.67, no.2, pp.55-65, 2016 (Released:2016-02-20)

参考文献数

33

被引用文献数

2

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本研究は手づかみ食べに関連する料理特徴について検討した. 手づかみ食べが最も多くみられる1か月間を後期, その直前2か月間を前期とした. 前期と後期の3か月間を合わせて手づかみ食べ発達時期とし, 前期と後期の料理特徴の差異について分析した. 対象は手づかみ食べ発達時期の乳幼児10名とした. 保育所の昼食時に週2回ビデオ観察を行った. 手づかみ食べ発達時期の手づかみ食べ頻度を料理区分別にみた結果,主菜が53.7±42.2%, 副菜が51.6±45.2%であり, それぞれ主食・汁物より有意に高かった. 次に, 主菜・副菜について前期と後期で手づかみ食べをする料理特徴を分析した. 前期は長さのみ (p<0.05), 後期は主材料の肉類 (p<0.05) ・調味における酢の使用 (p<0.01) ・調理法の揚げる (p<0.05) ・長さ (p<0.05) ・摂取率 (p<0.05) で有意差が認められた. 前期より後期で手づかみ食べに関連する料理特徴が多く認められたことから, 前期は料理特徴にあまり関係なく手づかみ食べをする時期であるのに対し, 後期は料理特徴が関係しやすい時期だと考えられた. さらに, 後期の手づかみ食べに関連する料理要因について二項ロジスティック回帰分析を行った結果, 調味の酢のみp=0.05であり, 手づかみ食べに関連のある要因は料理の要因だけではないことが示唆された.

著者

立間 徹

出版者

一般社団法人 表面技術協会

雑誌

表面技術 (ISSN:09151869)

巻号頁・発行日

vol.61, no.7, pp.478-478, 2010-07-01 (Released:2011-01-31)

参考文献数

13

著者

大塚 忠弘

出版者

一般社団法人 電気設備学会

雑誌

電気設備学会誌 (ISSN:09100350)

巻号頁・発行日

vol.26, no.1, pp.19-21, 2006-01-10 (Released:2015-06-17)

参考文献数

3

著者

黒田(澤井) 玲子 佐々木 裕 西川 智子 黒田 和道 桜井 孝治 山本 樹生 清水 一史

出版者

社団法人 日本食品科学工学会

雑誌

日本食品科学工学会誌 (ISSN:1341027X)

巻号頁・発行日

vol.58, no.10, pp.496-498, 2011-10-15 (Released:2011-11-30)

参考文献数

5

被引用文献数

1 2

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我々は,カリン(Chaenomeles sinensis)中の高分子ポリフェノールの季節性インフルエンザウイルス A/Udorn/ 307/72 (H3N2)に対する感染性中和活性および赤血球凝集抑制効果を既に報告している. カリン中の活性画分CSD3を用いて,新型インフルエンザウイルス A/Chiba/1001/2009 (H1N1) pdm に対する赤血球凝集抑制活性および感染性中和活性を評価したところ,5 μg/ml のCSD3で処理したウイルスは赤血球凝集価が約1/2に,感染性が約1/10に減少することが明らかになった.250 μg/mlの処理では感染価は1/3 000に減少したこれらの結果は,カリン中の抗インフルエンザウイルス活性成分は,H1N1新型インフルエンザウイルスに対しても有効であることを示す.更に,赤血球凝集価の減少以上に感染性が減少したことからウイルス吸着段階以降における抑制作用の存在が示唆された.

著者

塚田 義典 田中 成典 窪田 諭 中村 健二 岡中 秀騎

出版者

日本知能情報ファジィ学会

雑誌

知能と情報 (ISSN:13477986)

巻号頁・発行日

vol.27, no.5, pp.796-812, 2015-10-15 (Released:2015-11-13)

参考文献数

16

被引用文献数

1 6

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我が国では,高度経済成長期に集中整備された多くの道路橋が老朽化しており,適切な長寿命化修繕計画の策定が急務である.適切な点検・補修計画の策定,および工法の選定には,現況の形状を正確に把握する必要がある.しかし,現地での再測量作業には通行止め等の措置が付随するため,全国で約70万橋を対象に実施することは,コスト面と人的資源の面で困難である.この問題に対して,MMSを用いることにより道路の通行止めを行わずに道路橋上部工の現況を3次元で可視化する研究がなされている.しかし,MMSは道路に面した領域のみを計測対象にしていることから,路面だけのモデルにとどまり,上部工全体のモデルを生成することはできない.加えて,橋梁の下部工のモデル化も不可能である.そこで,本研究では,地上設置型のレーザスキャナとUAVを用いて取得した点群データから橋梁の上部工と下部工を一体とした3次元モデルの生成手法を提案する.