著者

佐藤 次郎

出版者

農業食料工学会

雑誌

農業機械学会誌 (ISSN:02852543)

巻号頁・発行日

vol.38, no.Supplement, pp.47-47, 1976-04-01 (Released:2010-04-30)

出版者

特定非営利活動法人 日本呼吸器外科学会

雑誌

日本呼吸器外科学会雑誌 (ISSN:09190945)

巻号頁・発行日

vol.30, no.Suppl, pp.S14-S14, 2016 (Released:2016-08-17)

著者

三輪 亮寿

出版者

一般社団法人 日本臨床薬理学会

雑誌

臨床薬理 (ISSN:03881601)

巻号頁・発行日

vol.40, no.6, pp.311-314, 2009 (Released:2009-12-25)

著者

Erina KOHYAMA Takao CHIKUMOTO Hiroyuki TADA Kiyoyuki KITAICHI Tadashi HORIUCHI Tetsuro ITO

出版者

(社)日本分析化学会

雑誌

Analytical Sciences (ISSN:09106340)

巻号頁・発行日

vol.32, no.8, pp.831-837, 2016-08-10 (Released:2016-08-10)

参考文献数

23

被引用文献数

20

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Synthetic compounds structurally derived from the mild stimulant 2-amino-1-phenyl-1-propanone, known as cathinone derivatives, are one of the largest growing class of synthetic designer drugs. The characterization of these drugs is complicated by the structural diversity and similarity of compounds in the ever-growing cathinone family. This paper demonstrates the successful application of gas chromatography–electron ionization–tandem mass spectrometry (GC-EI-MS-MS) and liquid chromatography–photodiode array (LC-PDA) analysis to differentiate structurally similar derivatives including regioisomers of cathinones. Product ion spectrometry of iminium ions allows for an univocal differentiation of the studied cathinones with the same aminoalkyl moiety. Furthermore, the product ion spectrometry of acylium ions and ultraviolet spectra obtained by LC-PDA enabled differentiation of regioisomers resulting from different substitution patterns on the aromatic ring. The validity of the method was demonstrated by the analysis of N-alkylated ortho-, meta-, and para-alkylcathinones along with the scaffolds of buphedrones and pentiophenones.

著者

谷口 雅人

出版者

一般社団法人 電気設備学会

雑誌

電気設備学会誌 (ISSN:09100350)

巻号頁・発行日

vol.25, no.3, pp.157-159, 2005-03-10 (Released:2015-07-29)

著者

藤井 知 杉江 他曾宏 村長 潔

出版者

公益社団法人 日本化学会

雑誌

日本化学会誌 (ISSN:03694577)

巻号頁・発行日

vol.1974, no.5, pp.867-873, 1974-05-10 (Released:2011-05-30)

参考文献数

19

被引用文献数

1

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硫酸鉄(II)と硫酸クロム(III)混合水溶液に水酸化カリウム溶液を加えて生成した水酸化鉄(II)を空気酸化して析出する四酸化三鉄を乾燥後,真空(10-5Torr)およびH2-H20混合ガス(H20/H2=2)の雰囲気下,200~500℃で加熱処理を行ない,粒子径,表面積および細孔構造(分布,細孔径,全細孔容積)の変化について,X線回折,電子顕微鏡ガス吸着により検討した。その結果,つぎのことが認められた。まず,四酸化三鉄沈殿を生成するさいは,クロム(III)を増加すると四酸化三鉄粒子の成長を抑制し,表面積をいちじるしく増大させた。沈殿物の加熱処理によって,1)四酸化三鉄の粒成長は400℃以上の温度でわずかに起こった。2)加熱にともなって含水量,表面積,細孔構造に変化が起こった。表面積は300℃までの温度で加熱脱水により増加するが,それ以上に加熱するとシンタリソグにより減少した。3)粒子径,表面積,細孔構造の変化は加熱雰囲気にも影響された。

著者

平田 清貴 松本 宜明 松本 光雄 村田 正弘 黒川 顕

出版者

日本救急医学会

雑誌

日本救急医学会雑誌 (ISSN:0915924X)

巻号頁・発行日

vol.10, no.11, pp.657-666, 1999-11-15 (Released:2009-03-27)

参考文献数

28

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わが国における急性ベンゾジアゼピン系薬物の重篤,かつ致死的な中毒の実態を解明することを目的として,1996年の1月から12月において,日本の59の三次救急医療施設に受け入れられた669人の急性ベンゾジアゼピン系薬物中毒症例と,同一期間における日本の27の都道府県警察管区(58.7%の都道府県に発生した)におけるベンゾジアゼピン系薬物を服用し,死亡した95例の法医学的検死例について解析し検討を行った。両群とも大多数が自殺目的によるベンゾジアゼピン系薬物中毒であり,その比率はそれぞれ82.7, 83.2%であった。フルニトラゼパム,トリアゾラム,エチゾラムそしてニトラゼパムが両群に共通して多く使用された薬物群であった。とくにフルニトラゼパムが統計的にも有意に検死例群に多く使用されていたことは,効果の発現が早い一方で生物学的半減期が長いとされるこの薬剤のもつ薬物動態上の特徴からも納得できる。一方,両群において,ベンゾジアゼピン系薬物中毒例の多くは血漿および尿中の検出試験を受けていなかった。このことは診断を誤らせる可能性と同時に急性中毒研究の科学的進歩の妨げにもなっていると考えられる。本研究において,6例が三次救急医療施設にベンゾジアゼピン系薬物を含む複合薬物中毒で搬入され死亡した。そのうち5人は来院時心肺停止状態の患者であった。よって急性ベンゾジアゼピン系薬物中毒に関連する死亡例のほとんどは医療機関外で,発見されず,処置も受けなかったために発生すると考えられる。また,大多数の患者が使用薬物を処方箋により入手していることから,本薬剤の無分別な処方と画一的な調剤は急性中毒発生の原因のひとつとなっていると考えられる。したがって,その急性中毒の発生を抑制するには薬歴管理や服薬指導を行い,ベンゾジアゼピン系薬物(とくにフルニトラゼパム,トリアゾラム,エチゾラム,ニトラゼパム)の臨床使用をより適切に管理することが重要といえよう。

著者

KIYOTAKA HIRATA YOSHIAKI MATSUMOTO JOJI TOMIOKA AKIRA KUROKAWA MITSUO MATSUMOTO MASAHIRO MURATA

出版者

Japanese Society of Pharmaceutical Health Care and Sciences

雑誌

病院薬学 (ISSN:03899098)

巻号頁・発行日

vol.24, no.4, pp.340-348, 1998-08-10 (Released:2011-08-11)

参考文献数

15

被引用文献数

2 6

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During 1996, 1188 patients with acute drug poisoning were admitted to 59 critical care departments in Japan. The patients were predominantly female (68.4%) and relatively young (69.2%, under the age of 40). Further analysis of the 1188 patients indicated that the majority (77.9%) were admitted as a result of deliberate self-poisoning, while 15.1 % of the cases were admitted due to accidental poisoning (unknown cause 7%). A total of 2517 drugs was taken by these patients. The most common group of drugs involved were benzodiazepines (32.1 %), followed by neuroleptics (12.2%), antidepressants (10.2%), analgesics (9.1%), antihistamines (7.3%) and barbiturates (6.2%).An important difference observed in the pattern of acute drug poisoning, when compared with that in other countries, was the preferential use of bromvalerylurea by young individuals for deliberate self-poisoning. This drug has not been used in any other country recently.There were twelve cases of fatal drug poisoning in the 59 critical care departments during 1996, including nine women. Four patients had taken barbiturates and six patients had taken a combination of benzodiazepines. In order to treat patients with acute drug poisoning, it is important to provide physicians with essential information on the incidence, mechanism of poisoning, and metabolism of the drug involved. In the case of rare drug poisoning, however, as it would take consideiable time for any one critical care department alone to amass enough admissions for generating a reliable information databese regarding management and prognosis, we therefore believe that a national approach is required to address the issue of management of patients with acute drug poisoning.

著者

藤沢 千春 玉木 彰 帯刀 未来 生島 秀樹 常峰 紘子 吉岡 聡

出版者

理学療法科学学会

雑誌

理学療法科学 (ISSN:13411667)

巻号頁・発行日

vol.31, no.4, pp.629-632, 2016 (Released:2016-08-31)

参考文献数

15

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〔目的〕対麻痺を呈した化学療法中の悪性リンパ腫症例に対して,ベルト電極式骨格筋電気刺激療法(B-SES)の廃用性筋萎縮の予防効果と安全性を検証した.〔対象と方法〕対象は悪性リンパ腫による脊髄損傷を呈した症例とした.B-SESによる廃用性筋萎縮予防の効果判定として初期,中間,最終に超音波診断装置による大腿四頭筋の筋厚測定とAmerican Spinal Injury Association運動機能評価(ASIA)を実施した.有害事象は有害事象共通用語基準を用いて評価した.〔結果〕骨格筋萎縮の予防は可能であったが,ASIAの改善は認められなかった.有害事象は全ての介入期間で認められなかった.〔結語〕B-SESは化学療法実施中の全ての介入期間で有害事象を生じず,廃用性筋萎縮の予防が可能であった.

著者

佐藤 晃一

出版者

日本独文学会

雑誌

ドイツ文學 (ISSN:03872831)

巻号頁・発行日

vol.1, pp.27-34, 1947-10-15 (Released:2008-06-30)

著者

平良 好利

出版者

JAPAN ASSOCIATION OF INTERNATIONAL RELATIONS

雑誌

国際政治 (ISSN:04542215)

巻号頁・発行日

vol.2010, no.160, pp.160_122-136, 2012-03-25 (Released:2012-06-15)

参考文献数

50

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By Article 3 of the San Francisco Peace Treaty signed in September 1951, the U.S. could continue to rule over Okinawa and have the exclusive right to maintain military bases there. After the ratification of the treaty in April 1952, people of Okinawa voiced opposition in regard to the use of land by the U.S. military. In June 1956, the U.S. authorities in Okinawa released a Report of the Price Subcommittee of the House Armed Services Committee (hereinafter called the Price Report) that supported the land policy proposed by the U.S. military. The Price Report recommended lump sum payments for fee title and accepted to the planned acquisition of additional land. However, the release of the report inflamed the opposition movement of the people of Okinawa.The purpose of this paper is to analyze the political process over the Price Report in 1956 by focusing on the attitudes of the Japanese Foreign Office and the U.S. Department of State.After the release of the Price Report, Okinawans requested that the Japanese Foreign Office negotiate with the U.S. government to solve the land dispute. During June and July of 1956, Foreign Minister Mamoru Shigemitsu requested the U.S. Ambassador John Allison to abandon lump sum payments and to reduce the acquisition of additional land.Following the recommendation of the U.S. Embassy in Japan, the U.S. State Department carefully reexamined the Price Report in regard to the possibility of abandoning lump sum payments in order to improve U.S.-Japan relations. However, shortly before the State Department was due to hold a conference with the Department of Defense (which supported the Price Report), the issue of abandoning lump sum payments was dropped, because the U.S. Consul General in Okinawa strongly recommended that the State Department not retreat from the Price Report. However, the State Department did ask the Pentagon to make some modifications, such as abandoning the acquisition of the fee title, in view of possible damage to U.S.-Japan relations.After this political process revealed the importance of taking into consideration the involvement of the Japanese Foreign Office and the U.S. State Department, it was clear that the U.S. military was not capable of ruling Okinawa on its own. Thereafter, U.S. military control over Okinawa was always considered in the context of Japan-U.S. relations. Therefore, the political process over the Price Report in 1956 marked the start of Japanese Foreign Office and U.S. State Department involvement in U.S. military control of Okinawa. Concomitantly, it also was the starting point of recognizing that the role of the U.S. military in Okinawa was an issue affecting Japan-U.S. relations.

著者

Yoshiaki Yamamoto Yuki Kawamura Yuki Yamazaki Tatsuro Kijima Toshiya Morikawa Yoshimune Nonomura

出版者

公益社団法人 日本油化学会

雑誌

Journal of Oleo Science (ISSN:13458957)

巻号頁・発行日

pp.ess14176, (Released:2015-02-09)

被引用文献数

2 22

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Palmitoleic acid is a promising bactericidal agent for cleansing products with alternative bactericidal abilities. In this study, we focus on the physical and biological activity of palmitoleic acid calcium salt (C16:1 fatty acid Ca salt) because it forms via an ion-exchange reaction between palmitoleic acid and Ca ions in tap water, and remains on the skin surface during the cleansing process. Here, we prepared C16:1 fatty acid Ca salt to investigate its crystal structure and physical and bactericidal properties. The Ca salt was a plate-shaped lamellar crystalline powder with a particle diameter of several micrometers to several tens of micrometers; it exhibited significant lubricity and alternative bactericidal activity against Staphylococcus aureus (S. aureus) and Propionibacterium acnes (P. acnes). We also examined other fatty acid Ca salts prepared from lauric acid (C12:0 fatty acid), palmitic acid (C16:0 fatty acid), and oleic acid (C18:1 fatty acid). The bactericidal activities and lubricity of the fatty acid Ca salts changed with the alkyl chain length and the degree of unsaturation. The C16:1 fatty acid Ca salt exhibited the strongest selective bactericidal ability among the four investigated fatty acid Ca salts. These findings suggest that C16:1 fatty acid and its Ca salt have potential applications in cleansing and cosmetic products.

著者

上滝 具貞 早野 延男 山中 久人

出版者

一般社団法人 日本機械学会

雑誌

日本機械学會論文集 (ISSN:00290270)

巻号頁・発行日

vol.43, no.366, pp.628-637, 1977-02-25 (Released:2008-03-28)

参考文献数

5

出版者

一般社団法人 日本高次脳機能障害学会

雑誌

高次脳機能研究 (旧 失語症研究) (ISSN:13484818)

巻号頁・発行日

vol.33, no.1, pp.123-124, 2013 (Released:2014-04-02)

著者

Rattaporn Sihawong Ekalak Sitthipornvorakul Arpalak Paksaichol Prawit Janwantanakul

出版者

(公社)日本産業衛生学会

雑誌

Journal of Occupational Health (ISSN:13419145)

巻号頁・発行日

vol.58, no.1, pp.16-24, 2016 (Released:2016-02-29)

参考文献数

46

被引用文献数

2 52

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Objective: All occupations expose workers to varied and unique conditions. The nature of work has been recognized as influencing the health of workers. Whether predictors for chronic neck and low back pain would be occupation-specific is unknown. This study aimed to identify predictors for chronic neck and low back pain in a cohort of office workers. Methods: A prospective study was carried out among 669 healthy office workers. At baseline, risk factors were assessed using a questionnaire and standardized physical examination. A symptomatic case was defined as an individual who reported pain greater than 30 mm on a 100-mm VAS, and chronic pain was defined as experiencing ongoing neck or low back pain for greater than 3 months over the past 6 months. Two regression models were built to analyze the risk factors for developing chronic neck and low back pain. Results: Of the sample, 17 and 27% of office workers who reported a new onset of neck or low back pain developed chronicity, respectively. Predictors for chronic neck pain were high body mass index, frequent neck extension during the work day, high initial pain intensity, and high psychological job demands. The development of chronic low back pain was associated with history of low back pain and high initial pain intensity. Conclusions: The findings suggest that predictors for chronic musculoskeletal pain in a subpopulation may be a subset of predictors identified in a general population or occupation specific. Successful management to prevent chronic musculoskeletal pain may also need to consider the patient's occupation.(J Occup Health 2016; 58: 16–24)

著者

万倉 三正 野田 泰子 森 昭胤

出版者

岡山医学会

雑誌

岡山医学会雑誌 (ISSN:00301558)

巻号頁・発行日

vol.124, no.1, pp.15-26, 2012-04-02 (Released:2012-04-29)

参考文献数

61

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Diabetes mellitus (DM) represents a global health and economical problem. Many patients with DM in Asia, South America, India and East Africa have traditionally used the water extract of unripe fruits of Momordica charantia (bitter melon) as some form of complementary and alternative medicine. Studies of laboratory animals have shown the beneficial blood-glucose lowering and anti-diabetic effects of this remedy. Some oral components that bring lower blood glucose level have been isolated : charantin (sterol glycosides), charantin (polypeptide) and cucurbine-type triterpenes. Part of their actions are related to AMP-activated kinase and repression of the oxidative stress that is increased in DM. Most clinical reports are not fully convincing due to the lack of randomized control studies. The present article reviews the pharmacological and clinical effects of bitter melon with special emphasis on the anti-diabetic effects, and some effects that would require caution in the context of human trials.

著者

折田 明子 三浦 麻子

出版者

一般社団法人 経営情報学会

雑誌

経営情報学会 全国研究発表大会要旨集 2011年秋季全国研究発表大会

巻号頁・発行日

pp.85, 2011 (Released:2011-12-01)

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日本国内において、インターネット上の電子掲示板等ネットコミュニティの利用に際して、利用者は実名を秘匿し、ニックネームなどの仮名を名乗る傾向がある。ただし、その仮名が継続して用いられるのか、その場限りなのかは明らかではなく、利用者が意識せずに仮名によって名寄せされた情報から本人が特定されるリスクもある。本稿では、読売新聞社による大型電子掲示板「発言小町」の利用者を対象にした調査結果をもとに、サイト利用者の「名乗り」の意識について考察する。回答者の約6割がネット上のみで通じるニックネームを名乗っており、実生活にひもづけられる名前はほとんど使われていない。また、積極的な書き込みをする利用者ほど、名乗る名前をその都度変化させていることが分かった。

著者

光石 一太 藤原 和子

出版者

環境技術学会

雑誌

環境技術 (ISSN:03889459)

巻号頁・発行日

vol.41, no.11, pp.695-700, 2012-11-20 (Released:2013-04-03)

参考文献数

15

被引用文献数

1

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炭粉末の利用拡大の観点から,炭粉末と天然バインダー(ロジン)を用いて圧縮成形することにより,炭成形体の作製を実施した.様々な温度,天然バインダー/炭粉末の混合比を設定し成形体作製条件の検討を行うとともに,曲げ特性,ホルムアルデヒド吸着性,水蒸気吸着性についてデータの蓄積を行った.

著者

遠藤 春香

出版者

一般社団法人 日本オリエント学会

雑誌

オリエント (ISSN:00305219)

巻号頁・発行日

vol.55, no.2, pp.17-32, 2013-03-31 (Released:2016-04-26)

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This paper discusses ‘Abd al-Wahhāb al-Sha‘rānī’s theory of the Perfect Man (insān kāmil), and examines his contribution to the history of Islamic thoughts. Sha‘rānī (d. 1565) was a Sufi thinker in Ottoman Egypt who belonged to the school of Ibn ‘Arabī (d. 1240). The focus of this paper is to analyze how Sha‘rānī inherited and developed Ibn ‘Arabī’s theory. The Perfect Man, as it is argued by Ibn ‘Arabī, refers to one who has attained unity with God and thereby attained the supreme state in Sufism. According to Ibn ‘Arabī, man was made in the image of God before the beginning of God’s creation of other creatures and therefore is capable of manifesting each of the names and attributes of God. The Perfect Man as a locus of God’s manifestation can synthesize two truths about God: God’s transcendence (tanzīh) and immanence (tashbīh), and God as the One and the many. The presence of the Perfect Man is important because he unifies the cosmos and keeps it one. This metaphysical theory of the Perfect Man taught by Ibn ‘Arabī was inherited by his followers. Many of them discussed the concept from the ontological point of view. However, Sha‘rānī, besides explicating the Perfect Man from the ontological aspect, developed it further by translating it into the social context. He developed the idea of the Perfect One (al-kāmil), who, according to Sha‘rānī, witnessed the source of the law (‘ayn al-sharī‘a) through a mystic experience. The various opinions of various people were originally derived from this source of the law. Thus, according to Sha‘rānī, the Perfect One can solve tensions that exist in society, since the Perfect One realizes the source of the law, into which opposing opinions can be ultimately resolved. Sha‘rānī thought that the splits of society into various parties can be unified through such a person. As this paper shows through its analysis, the Perfect Man and the Perfect One are the same concepts. Both hold within them the plane of God’s names and attributes and unify various dichotomies in the world. However, while the Perfect Man unifies the cosmos, the Perfect One unifies the society. attempted to contextualize the metaphysical-ontological concept of the Perfect Man in order to meet the needs of the society of his time. This paper concludes that, by applying Ibn ‘Arabī’s theory to this world, Sha‘rānī played an important role in further spreading Ibn ‘Arabī’s thoughts among the people of the Arab world.

著者

中西 悠喜

出版者

一般社団法人 日本オリエント学会

雑誌

オリエント (ISSN:00305219)

巻号頁・発行日

vol.52, no.2, pp.76-92, 2010-03-31 (Released:2014-03-31)

被引用文献数

1

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In classical discussions on the waḥdat al-wujūd (“Unity of Existence”), absolute existence (al-wujūd al-muṭlaq), that is “existence” itself, is recognized as the one and only reality. Existence is, in this system, identified with God, i.e. the “Necessarily Existent” (wājib al-wujūd), the entire universe being conceived to be self-manifestations of it. However, in the second half of the fourteenth century, this conception of existence was subjected to strong criticism by Sa‘d al-Dīn al-Taftāzānī (d. 1389/90). According to this Timurid philosopher-theologian, identifying existence with the Necessarily Existent is impossible, because “existence” itself is merely a secondary intelligible (al-ma‘qūl al-thānī) to which nothing in the external world corresponds. Shams al-Dīn Muḥammad ibn Ḥamzah al-Fanārī (d. 1431), with whom we shall deal in this paper, refuted this attack, thereby laying the ontological foundation of waḥdat al-wujūd. The aim of the present study is firstly to cast some light on this “Taftāzānī-Fanārī controversy” from the viewpoint of “Necessity of Existence,” which plays a decisive role in Fanārī’s whole refutation, and then to elucidate the Ottoman scholar’s strategy in demonstrating the identification of existence with the Necessarily Existent. Taftāzānī’s criticism revolves around the three themes: 1. classification of existence; 2. existence of the Necessarily Existent and His distance from impurities (qādhūrāt); 3. the Necessarily Existent and unity. In refuting all this criticism, Fanārī posits a concept of “relation” (nisbah). According to Taftāzānī, “existence” is a concept of “being” (mafhūn al-kawn). According to Fanārī, existence thus understood is nothing other than the relation of “existene” itself to the “beings” (kā’ināt), i.e. the created things. Fanārī salvages the identification of “existence” itself with the Necessarily Existent through this equation of what Taftāzānī calls “existence” with the relation of existence.