著者

羽田 孝司 夏秋 優 山西 清文

出版者

日本皮膚科学会大阪地方会・日本皮膚科学会京滋地方会

雑誌

皮膚の科学 (ISSN:13471813)

巻号頁・発行日

vol.10, no.3, pp.199-202, 2011 (Released:2012-10-23)

参考文献数

14

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29歳,女性。右腎血管筋脂肪腫摘出術の術前処置として,経口腸管洗浄剤ニフレック®を内服した。内服30分後から全身に熱感と紅斑が生じ,その後,顔面の腫脹,呼吸困難が出現した。輸液とステロイド投与を行い,症状は改善した。原因検索のため行ったプリックテストで,ニフレック®およびニフレック®に含まれるマクロゴール4000で陽性反応を示した。またマクロゴール400,1500,6000でもプリックテストを行い,陽性反応を示した。以上より自験例をニフレック®に含まれるマクロゴール4000によるアナフィラキシーと診断した。(皮膚の科学,10: 199-202, 2011)

著者

大塚 志穂 矢郷 香 大塚 友乃 岡田 明子 岡田 豊 中川 種昭 朝波 惣一郎

出版者

日本口腔内科学会

雑誌

日本口腔粘膜学会雑誌 (ISSN:13417983)

巻号頁・発行日

vol.10, no.2, pp.30-35, 2004-12-30 (Released:2010-02-25)

参考文献数

24

被引用文献数

1 1

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アンギオテンシン変換酵素 (以下ACE) 阻害剤は, まれに副作用として顔面, 口腔粘膜などの血管神経性浮腫を惹起する。呼吸困難を生じることもあり, 浮腫が咽頭部に及ぶと生命の危険性もある。今回われわれは, ACE阻害剤が原因として疑われた舌・口底部の血管神経性浮腫を経験したので報告する。患者は88歳, 女性で, 主訴は呼吸苦をともなう舌の腫脹であった。ACE阻害剤中止後, 1年4か月現在, 舌・口底部の浮腫の再発は認めていない。

著者

菊地 俊彦 高村 博光 藤山 大佑 須賀 美奈子 石丸 幸太郎 高野 潤 神田 幸彦 小林 俊光 吉見 龍一郎

出版者

耳鼻と臨床会

雑誌

耳鼻と臨床 (ISSN:04477227)

巻号頁・発行日

vol.47, no.4, pp.251-255, 2001-07-20 (Released:2013-05-10)

参考文献数

16

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アンギオテンシン変換酵素阻害剤 (ACE阻害剤) およびアンギオテンシンII受容体拮抗薬の重大な副作用として血管性浮腫の存在が知られている。今回、われわれは、ACE阻害剤の一つであるマレイン酸エナラプリルを内服後、重篤な喉頭浮腫を来した1症例を経験した。患者は62歳、男性で、マレイン酸エナラプリルの投与開始後、約1週間で発症しており、舌、喉頭および顎下部に高度の浮腫性病変を呈していた。ステロイドの投与およびマレイン酸エナラプリルの投与中止により治癒せしめることができた。現在、ニフェジピンにより血圧のコントロールを行っているが、血管浮腫の再発もみられず、経過良好である。このように、ACE阻害剤およびアンギオテンシンII受容体拮抗薬の投与により、時に致死的な高度の浮腫性病変を来すことがあるため、われわれ耳鼻咽喉科医も本疾患の存在を十分に理解しておく必要があろう。

著者

神谷 洋子 浅田 洸一 栃原 しほみ 山近 重生 石橋 克禮

出版者

一般社団法人 日本歯科薬物療法学会

雑誌

歯科薬物療法 (ISSN:02881012)

巻号頁・発行日

vol.22, no.1, pp.32-35, 2003-04-01 (Released:2010-06-08)

参考文献数

18

被引用文献数

1

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Recently, the use of angiotensin converting enzyme (ACE) inhibitors has increased and so angioedema as a side effect of ACE inhibitor administration is probably increasing. However, angioedema induced by ACE inhibitors has rarely been reported. We reported a case of angioedema (Quincke's edema) of the face that recurred following the administration of a double dose of ACE inhibitor.

著者

Yohei SAKURAI Mika MISHINA Toshifumi WATANABE

出版者

公益社団法人 日本獣医学会

雑誌

Journal of Veterinary Medical Science (ISSN:09167250)

巻号頁・発行日

pp.13-0471, (Released:2014-03-20)

被引用文献数

2

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A 9-year-old female dog was referred to Azabu University Veterinary Teaching Hospital for dysuria and dyschezia after ovariohysterectomy. After a series of diagnostic imaging, vaginal obstruction was suspected by vaginal fluid retention. Surgical repair was attempted three times to establish patency through the vagina and the vestibule by episiotomy and laparotomy. Another laparotomy was performed to remove the entire vaginal mucosal layer to prevent recurrence, and which resulted in favorable outcome. Histopathological examination revealed that the resected tissue was a cyst originated from mesonephric duct remnant. In the present case, the cyst was curable by the entire resection of the cyst lining membrane, and which could eradicate all the secretory cells with least damage to the urethral vasculature and innervation.

著者

Hee-Chun LEE Ji-Hyun KIM Cho-Hee JEE Jae-Hoon LEE Jong-Hyun MOON Na-Hyun KIM Jung-Hyang SUR Kyu-Woan CHO Byeong-Teck KANG Jeongim HA Dong-In JUNG

出版者

公益社団法人 日本獣医学会

雑誌

Journal of Veterinary Medical Science (ISSN:09167250)

巻号頁・発行日

pp.13-0315, (Released:2014-03-20)

被引用文献数

1 8

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A 9-year-old castrated male Shih-tzu dog was referred to us because of chronic vomiting. The patient’s hematological, radiographic, ultrasonographic, endoscopic, and histological examinations were evaluated for diagnosis. Hematologic analysis indicated moderate anemia and azotemia. Based on imaging study, oval-shape mass was identified in gastric pylorus area. A proliferative mass was found on endoscopic examination and we performed biopsy using grasping forceps. The histopathological findings of the biopsy specimens indicated hypertrophic gastritis and Y-U pyloroplasty was performed. However, the histopathological examination of surgically resected mass was identified as tubular adenocarcinoma of stomach. Then carboplatin chemotherapy was performed 4 times for 13 weeks. The clinical sign such as vomiting were resolved gradually after surgery and chemotherapy, and the patient’s condition was managed favorably until recently (30 months after surgery). This case report demonstrated clinical features, imaging studies, endoscopic characteristics, histopathological and immunohistochemical features of gastric tubular adenocarcinoma as early gastric cancer in a dog.

著者

Shinya HANAOKA Yuichi INDO Terumitsu HIRATA Tomoyuki TODOROKI Taro ARATANI Teppei OSADA

出版者

公益社団法人 土木学会

雑誌

Journal of JSCE (ISSN:21875103)

巻号頁・発行日

vol.1, no.1, pp.286-297, 2013 (Released:2013-10-18)

参考文献数

2

被引用文献数

10

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During the initial stage of a disaster, aircraft operate intensively and simultaneously use several airports as bases, given their mandate to promptly perform their duties. Previously, disaster management faced challenges such as insufficient airport apron space, shortage of aircraft fuel, and inadequate information sharing among various involved organizations. During the Great East Japan Earthquake, aircraft— pri- marily civilian and government helicopters—used the Iwate Hanamaki Airport, Yamagata Airport, and Fukushima Airport as bases immediately after the disaster struck. These aircraft performed tasks such as information gathering, emergency rescue, and personnel and goods transport. For this study, we interviewed personnel in the organizations involved in operating these aircraft and airports during the disaster. Further, we considered the operational realities of disaster response activities at each airport to identify the lessons learned and challenges met. We present our findings and detail the role of an airport as a disaster management facility and the challenges faced by an airport during a disaster.

著者

Liren QIAN Fei CAO Jianguo CUI Yicun WANG Yuecheng HUANG Yunhai CHUAI Luqian ZAHO Hao JIANG Jianming CAI

出版者

Journal of Radiation Research 編集委員会

雑誌

Journal of Radiation Research (ISSN:04493060)

巻号頁・発行日

vol.51, no.6, pp.741-747, 2010 (Released:2010-11-23)

参考文献数

35

被引用文献数

67

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Most ionizing radiation-induced damage is caused by hydroxyl radicals, and the selective reduction of hydroxyl by hydrogen in vitro has been demonstrated previously. Irradiation of the heart can cause chronic cardiac disease. This study was designed to test the hypothesis that hydrogen-rich water (pure water saturated with molecular hydrogen), which is easy to use, induces cardioprotection against ionizing irradiation injury in mice. In this paper, we demonstrate that hydrogen can protect myocardium degeneration from radiation-induced injury, decrease myocardium malondialdehyde (MDA), 8-hydroxydeoxyguanosine (8-OHdG) levels, and increase myocardium endogenous antioxidants in vivo. We suggest that hydrogen has a cardioprotective effect against radiation induced injury.

著者

山口 喜朗 井上 和馬 斎藤 直

出版者

公益社団法人 日本アイソトープ協会

雑誌

RADIOISOTOPES (ISSN:00338303)

巻号頁・発行日

vol.55, no.2, pp.89-95, 2006-02-15 (Released:2011-03-01)

参考文献数

5

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A virtual reality education and training system was developed for radiation workers. The function of the system is designed as a scenario which is programmed with a proprietary script language capable of defining motion of objects created by three-dimensional (3D) modeling software, user interaction, sounds and text strings displayed in the scene. Combining these functions enables the system to provide lectures and to judge the user's action. The system consists of the 3D model of the radiation facilities and three modes of scenarios (guidance, training and end-of-course examination) including the procedure to enter and exit, experiment, measurement, radioactive waste classification and accidents. By combining these modes, the trainee of education and training is possible to learn safety handling and how to act in the case of fire or earthquake.

著者

Sang-Heon Lee

出版者

理学療法科学学会

雑誌

Journal of Physical Therapy Science (ISSN:09155287)

巻号頁・発行日

vol.26, no.2, pp.239-241, 2014 (Released:2014-02-28)

参考文献数

20

被引用文献数

1 2

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[Purpose] The purpose of this study was to analyze the activity engagement of the retiree population in South Korea. [Methods] The Korean-Activity Card Sort (K-ACS) was used to collect research data. A One-way ANOVA and post-hoc comparisons showed significant group effects among three age groups. The independent t-tests was used to analyze the differences in mean retained level of activity (MRA) between men and women. [Results] The one-way ANOVA showed statistically significant differences in MRA among different age groups. Scheffé’s test revealed a statistically significant decrease in MRA in Group A, aged more than 75 years, as compared to the other two age groups. When participants were divided by gender, MRA of instrumental activities showed a statistically significant difference between the 65–74 years group and the 55–65 years group, but no difference in females of the leisure activities among the age groups. The independent t-tests demonstrated significant gender differences in MRA of activity of the 55–64 years group. [Conclusion] These findings suggest that health professionals should monitor the changes in retained level of activity after age 75, to maintain their engagement, and the importance of age-, gender- and activity-specific analyses in order to identifying patterns of activity engagement.

著者

藤広 満智子

出版者

日本医真菌学会

雑誌

Medical Mycology Journal (ISSN:21856486)

巻号頁・発行日

vol.54, no.2, pp.107-110, 2013 (Released:2013-06-11)

参考文献数

14

被引用文献数

1

著者

北野 旦浩 今井 章

出版者

日本認知科学会

雑誌

認知科学 (ISSN:13417924)

巻号頁・発行日

vol.17, no.3, pp.670-680, 2010 (Released:2011-03-08)

参考文献数

14

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This study investigated the effects of domain-specific geographical and meteorological knowledges and general visual-spatial abilities on the comprehension of simple weather maps. Thirty participants with low meteorological knowledge and 16 with high knowledge, were both administered tests of geographical and meteorological knowledges, four kinds of visual-spatial abilities, and the task of weather map comprehension. The results indicated that the participants having high meteorological knowledge generally showed better performance at both of the meteorological test and the task of weather map comprehension than participants having low knowledge. Multiple regression analyses revealed that the total score and the basic-level score of the task of weather map comprehension were explained by the meteorological knowledge about 46% and 31%, respectively. Additionally flexibility of closure as the one of the general visual-spatial abilities, together with the meteorological knowledge, contributed 58% to the advanced-level score of the task of weather map comprehension. For the low knowledge participants, speed of closure was significantly important to resolve the task of weather map comprehension. It is suggested that the meteorological knowledge is crucially important, and the flexibility of closure may aid, for the comprehension of simple weather map.

著者

Yoshinori KATAKURA Eriko NAKATA Yukiko TABIRA Takumi MIURA Kiichiro TERUYA Toshie TSUCHIYA Sanetaka SHIRAHATA

出版者

(社)日本農芸化学会

雑誌

Bioscience, Biotechnology, and Biochemistry (ISSN:09168451)

巻号頁・発行日

vol.67, no.4, pp.815-821, 2003 (Released:2003-06-28)

参考文献数

23

被引用文献数

12

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We have previously reported that transforming growth factor β (TGF-β) triggers two independent senescence programs, 1) replicative senescence dependent upon telomere shortening and 2) premature senescence independent of telomere shortening, in the cell line of A549 human lung adenocarcinoma. In this study, we examined the possibility that cancer cell tumor phenotypes could be suppressed by forced senescence. We used A549 cells treated with TGF-β for a long time (over 50 days), where senescence was induced in a telomere-shortening-dependent or an independent way. Fully senescent A549 cells were elongated, acquired contact inhibition capabilities when reaching confluence, and secreted the senescence-associated cytokine IL-6. Furthermore, senescent A549 cells had no tumorigenicity in nude mice. These results indicate that the forced induction of senescence in cancer cells may be a novel and potentially powerful method for advancing anti-cancer therapy.

著者

Toyotaka SATO Shin-ichi YOKOTA Risa ICHIHASHI Tomoka MIYAUCHI Torahiko OKUBO Masaru USUI Nobuhiro FUJII Yutaka TAMURA

出版者

公益社団法人 日本獣医学会

雑誌

Journal of Veterinary Medical Science (ISSN:09167250)

巻号頁・発行日

pp.13-0144, (Released:2014-03-18)

被引用文献数

7

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Understanding the prevalence of antimicrobial-resistance and the relationship between emergence of resistant bacteria and clinical treatment can facilitate design of effective treatment strategies. We here examined antimicrobial susceptibilities of Escherichia coli isolated from dogs admitted to a university hospital (University hospital) and companion animal clinics (Community clinics) in the same city, and investigated underlying multidrug-resistance mechanisms. The prevalence of E. coli with intermediate and resistant interpretations to ampicillin (AMP), enrofloxacin (ENR) and chloramphenicol (CHL) was higher in the University hospital than in the Community clinics cases. Use of antimicrobials, including fluoroquinolone, was also significantly higher in the University hospital than in the Community clinics cases. Upon isolation using ENR-supplemented agar plates, all ENR-resistant isolates had 3–4 nucleotide mutations that accompanied by amino acid substitutions in the quinolone-resistance-determining regions of gyrA, parC and parE, and 94.7% of all isolates derived from the University hospital showed AMP and/or CHL resistance, and possessed blaTEM and/or catA1. The average mRNA expression levels of acrA, acrB and tolC, and the prevalence of organic solvent tolerance, in isolates derived from ENR-supplemented agar plates were significantly higher in the University hospital than in the Community clinics isolates. Thus, E. coli derived from the University hospital cases more often showed concomitant decreased susceptibilities to aminopenicillins, fluoroquinolones, and CHL than did those derived from the Community clinics; this was related to an active AcrAB–TolC efflux pump, in addition to acquisition of specific resistance genes and genetic mutations.

著者

網谷 有希子 須藤 紀子 笠岡(坪山) 宜代 石川 文子 迫 和子

出版者

公益社団法人 日本栄養士会

雑誌

日本栄養士会雑誌 (ISSN:00136492)

巻号頁・発行日

vol.57, no.3, pp.192-200, 2014 (Released:2014-03-18)

参考文献数

13

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保育所での災害対策について、東日本大震災(H23.3.11)(以下、3.11 大震災)前後での食料等の備蓄の変化、食事提供に関する訓練の実施状況、被災時の適切な対応を明らかにするため、首都圏政令A 県の指定都市B の保育課に勤務する管理栄養士と保育士、B 市内私立保育所C の施設長、保育士、栄養士を対象にグループインタビューを実施した。食料等の備蓄は震災前に比べて、アレルギー対応食品の備蓄、分散備蓄などの点で質・量ともに大きく改善されていた。3.11 大震災後、市内全公立保育所に対して、行政による備蓄食品の一括購入が行われていた。私立保育所C では、1 日4 食3 日分の災害時メニュー計画書の作成に取り組み、それをもとに備蓄整備を進めていた。一方で、避難訓練は毎月実施されているものの、子どもに備蓄食品を保育所で食べさせる訓練や、炊き出しを想定した大量調理の訓練は行われていなかった。加えて3.11 大震災時には、備蓄食品を、入所児だけでなく職員や保護者が食べる場面も見られた。

著者

遠藤 玄 福島 E.文彦 桑原 裕之 広瀬 茂男

出版者

一般社団法人 日本ロボット学会

雑誌

日本ロボット学会誌 (ISSN:02891824)

巻号頁・発行日

vol.31, no.2, pp.198-205, 2013 (Released:2013-04-15)

参考文献数

11

被引用文献数

1

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This paper introduces the outline of a creativity education course “machine creation” that has been conducted at the Department of Mechano-Aerospace Engineering, Tokyo Institute of Technology, for 21 years. The course is designed to provide students with extensive opportunities to work with real objects to bridge classroom lectures and hands-on experiences. The students work as a team within a time limitation under budget to create a “street performance robot” which can entertain audience. We assume that students can efficiently learn about a process of product development through this course from planning of the robot to the final presentation of the robot. To evaluate this assumption, we carried out questionnaire survey for the current students and alumni who are currently working as engineers in the real world. The results suggest that this course can provide a valuable experience for students and many alumni agree with our educational methodology.

著者

大谷 正幸

出版者

佛教文化学会

雑誌

佛教文化学会紀要 (ISSN:09196943)

巻号頁・発行日

vol.2004, no.13, pp.177-198, 2004-11-10 (Released:2009-08-21)

参考文献数

24

著者

多田隈 理一郎

出版者

一般社団法人 日本ロボット学会

雑誌

日本ロボット学会誌 (ISSN:02891824)

巻号頁・発行日

vol.31, no.1, pp.45-46, 2013 (Released:2013-02-17)

著者

Luigi CECI Fabrizio IARUSSI Beatrice GRECO Rosanna LACINIO Stefania FORNELLI Grazia CARELLI

出版者

公益社団法人 日本獣医学会

雑誌

Journal of Veterinary Medical Science (ISSN:09167250)

巻号頁・発行日

pp.13-0365, (Released:2014-03-07)

被引用文献数

9 27

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Tick-borne diseases are widespread in tropical and temperate regions and are responsible for important economic losses in those areas. In order to assess the presence and prevalence of various pathogens in southern Italy, we retrospectively analyzed cattle blood samples collected for a previous study in 2000 using reverse line blot (RLB) hybridization. The study had been carried out in three regions of southern Italy on 1,500 randomly selected and apparently healthy adult cattle. RLB showed that 43.7% of the cattle were positive for nine different species of haemoparasites, with either a single infection or a mixed infection. Theileria buffeli was the most common species found, being present in 27.3% of the animals, followed by Anaplasma marginale in 18.1%, Anaplasma centrale in 13.8%, Babesia bigemina and Anaplasma bovis in 4.2%, Anaplasma phagocytophilum in 1.7%, Babesia bovis in 1.6%, Babesia major in 0.2%, and Babesia divergens in 0.1%. Complete blood counts showed different degrees of anaemia in 363 animals (24.2%) and of these, 169 were RLB-positive for at least one pathogen. Among the ticks that were collected from the cattle, the following species were identified: Rhipicephalus bursa, Ixodes ricinus, Hyalomma marginatum, Boophilus annulatus, Dermacentor marginatus and Haemaphysalis (sulcata, parva, inermis and punctata). The results obtained confirmed the spread of endemic tick-borne pathogens in the regions studied.

著者

竹原 祥子 下山 和弘

出版者

一般社団法人 日本老年歯科医学会

雑誌

老年歯科医学 (ISSN:09143866)

巻号頁・発行日

vol.21, no.4, pp.403-406, 2007-03-31 (Released:2014-02-26)

参考文献数

7

被引用文献数

1