著者
田中 功 溝口 照康
出版者
公益社団法人 日本顕微鏡学会
雑誌
顕微鏡 (ISSN:13490958)
巻号頁・発行日
vol.40, no.2, pp.116-119, 2005-07-31 (Released:2009-06-12)
参考文献数
20
被引用文献数
1
著者
溝口 照康 田中 功
出版者
日本結晶学会
雑誌
日本結晶学会誌 (ISSN:03694585)
巻号頁・発行日
vol.47, no.1, pp.73-78, 2005-02-28 (Released:2010-09-30)
参考文献数
19
被引用文献数
1

This paper reviews theoretical calculation of ELNES using first principles band structure methods. A core-hole is included in the calculation, and the matrix elements of the electric dipole transition between the ground state and the final state are computed. The satisfactory reproductions of the experimental spectra are commonly brought about by employing the sufficient large supercells. The orientation dependence of ELVES for wurtzite-A1N is discussed. The dependence was found to be much larger in K edges as compared to the L2.3 edge. The large projection dependence is predicted in O-K ELNES of SrTiO3. It was found that those spectral changes according to the position of the projection are caused by the unidirectional Ti-O-Ti bond in SrTiO3. Theoretical calculation of the low loss spectrum from SrTiO3 is also discussed.
著者
後町 武志 石田 祐一 高橋 直人 三森 教雄 柏木 秀幸 矢永 勝彦
出版者
日本臨床外科学会
雑誌
日本臨床外科学会雑誌 (ISSN:13452843)
巻号頁・発行日
vol.71, no.3, pp.696-701, 2010 (Released:2010-09-25)
参考文献数
39
被引用文献数
1

症例は64歳,女性.進行胃癌に対する胃全摘術+脾摘術施行後S-1を内服中で再発徴候は認めていなかった.術後2年5カ月目に発熱,下痢,意識障害にて緊急入院.精査にてインフルエンザ桿菌性髄膜炎・菌血症を発症しているoverwhelming postsplenectomy infection(OPSI)と診断した.抗菌剤,ステロイドによる治療で軽快し第50病日に退院した.OPSIは脾摘後に敗血症,髄膜炎などで突然発症する重症感染症で,発症すると高率に死亡することが知られている.予防として適切な予防的抗菌薬投与,患者教育,ワクチン接種が重要とされるが,脾摘後長期間経過後に発症することもあり,脾摘後患者では常にOPSIを念頭におく必要がある.今回われわれは胃癌に対する脾摘術後化学療法中に発症したインフルエンザ桿菌によるOPSIの1例を経験したので,文献的考察を加えて報告する.
著者
Naoshi Kakitsuba Igor B. Mekjavic Tetsuo Katsuura
出版者
日本生理人類学会
雑誌
Journal of PHYSIOLOGICAL ANTHROPOLOGY (ISSN:18806791)
巻号頁・発行日
vol.26, no.3, pp.403-408, 2007 (Released:2007-07-20)
参考文献数
12
被引用文献数
3 5

The purpose of the study was to investigate the degree of subject variability in the peripheral and core temperature thresholds of the onset of shivering and sweating. Nine healthy young male subjects participated in three trials. In the first two trials, wearing only shorts, they were exposed to air temperatures of 5°C and 40°C until the onset of shivering and sweating, respectively. In the second experiment, subjects wore a water perfused suit that was perfused with 25°C water at a rate of 600 cc/min. They exercised on an ergometer at 50% of their maximum work rate for 10–15 min. At the onset of sweating, the exercise was terminated, and they remained seated until the onset of shivering, as reflected in oxygen uptake. In the first two trials, rectal temperature (Tre) was stable, despite displacements in skin temperature (Tsk), whereas in the third trial, Tsk (measured at four sites) was almost constant (30–32°C), and the thermoregulatory responses were initiated due to changes in Tre alone. The results of the first two trials established the peripheral interthreshold zone, whereas the results of the third trial established the core interthreshold zone. The results demonstrated individual variability in the peripheral and core interthreshold zones, a proportional correlation between both zones (r=0.87), and a relatively higher contribution of adiposity in both zones as compared with those of other non-thermal factors such as height, weight, body surface area, surface area-to mass ratio, and the maximum work load.
著者
葛 宗涛 高 偉 竹内 一弘 清野 慧
出版者
公益社団法人 精密工学会
雑誌
精密工学会誌 (ISSN:09120289)
巻号頁・発行日
vol.63, no.7, pp.967-971, 1997-07-05 (Released:2010-02-16)
参考文献数
15

2-D software datum named as the 2-D mixed method has been constructed to measure mirror surface profiles. The probe of this method consists of two displacement and two angle sensors. Differential calculation of outputs of these four sensors eliminates pitch, roll and the z-directional translation errors of the scanning stages. An autonomous procedure to estimate and compensate the zero-adjustment error among these four sensors is also proposed. By using this software datum, 2-D profiles of ultra-precision surfaces can be measured absolutely without using any external reference. An experimental probe for realizing the 2-D mixed method has been developed and a mirror surface of 128 mm long and 64 mm wide was measured with the probe. Repeatability of measurements and reproducibility compared with the differential angle method have shown high reliability of the proposed method
著者
内納 和浩 山口 広貴 安藤 友三 横山 博夫
出版者
公益社団法人 日本化学療法学会
雑誌
日本化学療法学会雑誌 (ISSN:13407007)
巻号頁・発行日
vol.54, no.4, pp.321-329, 2006-07-10 (Released:2011-08-04)
参考文献数
13

38℃以上の咽頭炎. 扁桃炎, 急性気管支炎を対象としたlevofloxacin (LVFX) の特別調査症例8,856例のうち, 感染症以外の合併症・基礎疾患を有さない7,597例について昨ステロイド性消炎鎮痛薬 (nonsteroidal anti-inflammatory drugs: NSAIDs) 併用時の安全性を検討した。NSAIDsの併用率は64.4% (4,890/7,597) で, 「併用注意」と記載されているフェニル酢酸系・プロピオン酸系NSAIDsと併用率は37.2% (2,828/7,597) であった。NSAIDs併用有無別の中枢神経系副作用発現率は, NSAIDs非併用群で0.04% (1/2,707), フェニル酢酸系・プロピオン酸系NSAIDs併用群で0.07% (2/2,828), その他のNSAIDs併用群で0.10% (2/2,062) であり, NSAIDs非併用群とNSAIDs併用群との間に有意差は認められなかった。中枢神経系副作用の種類は, めまいが2例, ふらつき感不眠, 眠気が各1例報告されたが, 痙攣は認められなかった。LVFXの1日投与量別の中枢神経系副作用発現率は, 200mg分2/日投与群で0% (0/458), 300mg分3/日投与群で0.07% (4/5,716), 400mg分2/日投与群で0.10% (1/1.031), 600mg分3/日投与群で0% (0/65) であり, 4群間に有意差は認められず, NSAIDs併用の有無で層別した結果でも有意差は認められなかった。年齢別の中枢神経系副作用発現率は, 65歳未満で0.06% (4/7,088), 65~74歳で0.28% (1/358), 75歳以上で0% (0/151) であり, 有意差は認められなかった。さらにNSAIDs併用の有無で層別した結果でも有意差は認められなかった。以上の結果より, 基礎疾患・合併症を有さない症例においてLVFXに対するNSAIDsの影響はきわめて小さいことが示唆された。
著者
長野 宣道 松尾 孝美 伊藤 隆志 友成 健一朗 白石 順二
出版者
公益社団法人 日本放射線技術学会
雑誌
日本放射線技術学会雑誌 (ISSN:03694305)
巻号頁・発行日
vol.68, no.11, pp.1474-1485, 2012-11-20 (Released:2012-11-21)
参考文献数
28

We proposed a method for a computer-aided diagnosis system that distinguishes between benign and malignant lesions in gastrointestinal digital radiography. To begin with, the level set method was applied in order to extract a tumor region from the image which was smoothed by the bilateral filter. Next, we selected four image features with the large SN ratio among various image features obtained from a tumor region using the Mahalanobis-Taguchi method, which has been employed mainly in quality engineering. The selected four image features—circularity, irregularity, size, and perimeter—were used as input data for the artificial neural network, which was employed for distinction between benign and malignant lesions. By using 43 regions of interest cropped from the 43 clinical cases, the area under the ROC curve (AUC) of diagnostic accuracy for the classification obtained with this proposed method was 0.970, whereas the average AUC obtained with 7 human observers (3 radiologists and 4 radiological technologist) was 0.941.
著者
坂本 文徳 大貫 敏彦 香西 直文 山崎 信哉 吉田 善行 難波 謙二
出版者
一般社団法人 日本原子力学会
雑誌
日本原子力学会和文論文誌 (ISSN:13472879)
巻号頁・発行日
vol.12, no.4, pp.257-266, 2013 (Released:2013-11-15)
参考文献数
20
被引用文献数
4 5

The local area distribution and relocation of radioactive cesium deposited in trees after the 2011 tsunami-related accident at the Fukushima Daiichi Nuclear Power Plant (FDNPP) have been studied by measuring the spatial distribution of cesium on/in trees by autoradiography analysis. Samples of trees were collected from places located between 4 and 55 km from FDNPP approximately 2, 8, 20, and 22 months after the accident. The autoradiography analyses of Cryptomeria japonica, Torreya nucifera, and Thujopsis dolabrata var. hondae samples collected approximately 2 and 8 months after the accident showed that radioactive Cs was mainly distributed as spots on the branches and leaves of the trees emerged before the accident, and was detected in negligible amounts in new branch and leaves that emerged after the accident. On the contrary, radioactive Cs was detected at the outermost tip of the branches in the trees collected 20 months after the accident. Morus alba samples collected 22 months after the accident contained radioactive Cs inside and outside their stems, even though no radioactive Cs was detected in their roots, strongly suggesting that a certain amount of radioactive Cs was translocated from the outside to the inside of stems. These results indicate that the distribution of radioactive Cs deposited on/in the trees gradually changes with time (scale: year).
著者
中嶋 優 一川 誠
出版者
日本感性工学会
雑誌
日本感性工学会論文誌 (ISSN:18828930)
巻号頁・発行日
vol.8, no.1, pp.137-143, 2008-12-20 (Released:2010-06-28)
参考文献数
17
被引用文献数
1

Although previous studies have examined what kind of object arrangement could give observer beautiful impression, they have not achieved agreement. While some studies found observers' preference for the arrangements whose centroids were congruent with the center of the picture frame, the other studies found the observers' preference for the arrangement whose centroids were in the right side in the frame. The main purpose of this study is to solve this disagreement among previous studies. We conducted three experiments in which concreteness of the picture was manipulated, and observers rated their impression for the pictures with different centroid position. We used black circles (Experiment 1), concrete objects on white background (Experiment 2), and concrete objects on backgrounds of natural scenes (Experiment 3). Only in Experiment 3, we found that observers consistently preferred for the pictures whose centroid of the arrangement was in right side. Our results indicate that concreteness of the pictures caused the biased preferencefor the right side of the pictures.
著者
Akira Sato Michio Sata Kenji Ikeda Takashi Kumada Namiki Izumi Yasuhiro Asahina Yukio Osaki Kazuaki Chayama Shuichi Kaneko Akito Sakai Morikazu Onji Yoichi Hiasa Takumi Omura Itaru Ozeki Osamu Yokosuka Shuichiro Shiina Mariko Itsubo Shuhei Nishiguchi Katsuharu Hirano Tatsuya Ide Shotaro Sakisaka Takahiro Yamasaki Isao Hidaka Masatoshi Tanaka Soo Ryang Kim Takafumi Ichida
出版者
一般社団法人 日本内科学会
雑誌
Internal Medicine (ISSN:09182918)
巻号頁・発行日
vol.52, no.24, pp.2701-2706, 2013 (Released:2013-12-15)
参考文献数
32
被引用文献数
4 14

Objective We attempted to elucidate the clinical features of chronic hepatitis C patients who develop hepatocellular carcinoma (HCC) after achieving a sustained viral response (SVR) to interferon (IFN) therapy. Methods The clinical features of 130 patients at 19 hospitals who developed HCC after obtaining an SVR were retrospectively reviewed. Results Overall, 107 (82%) of the 130 patients were men, with 92 (71%) being ≥60 years of age and 76, 38 and 16 developing HCC within 5, 5-10 and 10-16.9 years after IFN therapy, respectively. Before receiving IFN therapy, 92 (71%) patients had cirrhosis and/or a low platelet count (<15×104 cells/μL). Lower albumin (<3.9 g/dL) and higher alpha fetoprotein (AFP) (≥10 ng/mL) levels were identified in a multivariate analysis to be independent variables of the development of HCC within five years after IFN therapy. Among 4,542 SVR patients, HCC occurred in 109 (2.4%) during a 5.5-year follow-up period, thus resulting in an occurrence rate of 4.6% for men and 0.6% for women. Conclusion SVR patients with lower albumin or higher AFP levels require careful assessments to prevent early HCC development after IFN therapy. HCC occurrence within >10 years of IFN therapy is not uncommon, and the risk factors remain uncertain, thus suggesting that all SVR patients should undergo long-term follow-up examinations for HCC development.
著者
Shigenaga Takano Yuji Takeuchi Daisuke Takeuchi Kohtaro Osakada
出版者
(社)日本化学会
雑誌
Chemistry Letters (ISSN:03667022)
巻号頁・発行日
pp.131065, (Released:2013-12-20)
被引用文献数
17

Dinuclear Co and Fe complexes with a double-decker structure supported by macrocyclic ligands having two bis(imino)pyridine and xanthene groups were synthesized. The dinuclear Fe complex catalyzes ethylene oligomerization in the presence of MMAO or Me3Al to give oligoethylene with ethyl and/or propyl branches due to cooperative interaction of two Fe centers.
著者
梅原 宏司
出版者
Japan Association for Cultural Economics
雑誌
文化経済学 (ISSN:13441442)
巻号頁・発行日
vol.5, no.3, pp.31-45, 2007-03-31 (Released:2009-12-08)
参考文献数
111

1960年代から70年代にかけ、国家レベルの保守政治に対して革新自治体が行なった政策は、「自治」「市民」という言葉の問い直しに基づくものであった。それは「市民」を政治的に活動する存在として考え、「自治」を市民の参加としてとらえるものであった。これをリードしたのが、政治学者の松下圭一であり、彼はその一環として「文化行政」を構想した。本稿は、松下の考えを検証し、「革新」という考えが「文化」に与えた影響を考察する。
著者
村山 英晶 影山 和郎 成瀬 央 島田 明佳 鵜沢 潔
出版者
日本複合材料学会
雑誌
日本複合材料学会誌 (ISSN:03852563)
巻号頁・発行日
vol.28, no.5, pp.176-188, 2002-09-15 (Released:2009-08-11)
参考文献数
14
被引用文献数
1 1

The purpose of structural health monitoring (SHM) is to lead a structure to be safer at a lower cost. In SHM, it is important to evaluate the actual state of the structure. Recently, fiber-optic sensors have been developed actively, and one can measure nearly all of the physical measurands of interest by them. Since they also have excellent characteristics such as high sensitivity, immunity from electromagnetic interference, good mechanical characteristics and distributed configuration, they have been applied to “smart structures.” Capability of quasi or fully distributed sensing is especially the significant advantage compared to conventional sensors. We have applied the fiberoptic distributed sensors to SHM in the field and we developed the integrated systems with the fiberoptic sensors and CAD/CAE for two large composite structures. These systems could give us useful information on the structural state, such as deformation and temperature during/after manufacture.
著者
阿部 智明 中野 裕司 倉本 宣
出版者
日本緑化工学会
雑誌
日本緑化工学会誌 (ISSN:09167439)
巻号頁・発行日
vol.30, no.1, pp.344-347, 2004 (Released:2005-11-22)
参考文献数
8
被引用文献数
2 2

日本産のコマツナギと中国産のコマツナギをアロザイム分析して対立遺伝子の構成を比較した。対立遺伝子の構成は日本の4つの産地では類似していたが,中国産の種子は大きく相違していた。自生種の使用が求められる地域において中国産コマツナギを用いることには慎重になるべきである。
著者
中林 一樹
出版者
公益社団法人 東京地学協会
雑誌
地学雑誌 (ISSN:0022135X)
巻号頁・発行日
vol.110, no.6, pp.938-949, 2001-12-25 (Released:2009-11-12)
参考文献数
8
被引用文献数
1

In the 21st Century, it has been announced that several earthquakes will occur beneath Tokyo Capital Region. The Tokyo Metropolitan Government implements two kinds of hazard assessments for countermeasures against the earthquake disasters. One is the disaster damage estimation for Tokyo and a disaster scenario for Earthquake that occurres just beneath Cental Tokyo. According to the Report published in 1997, approximately 378, 000 buildings will be burnt down, 43, 000 buildings will be demolished, 7, 200 people will be killed. A disturbance of the water supply will continue for one month and the interruption of piped gas will continue for two months, more than two million people will be evacuated to shelters located mainly in public schools. The other assessment concerns research on the vulnerability of built-up areas against earthquakes measured according to each community area. According to the area vulnerability research, the most vulnerable areas are located as a ring-zone around the CBD and as a finger-zone along Japan Railway's Chuo-line from central Tokyo to the west suburban region (Pictorial 4-1). These zones are made up wooden houses in crowded areas without city planning nor building permission.TMG learned much from the Kobe Earthquake of 1995 and has enlarged earthquake countermeasures to make Tokyo an earthquake-resistant city and to secure effective disaster countermeasures, quick recovery and reconstruction to protest the livelihood of the populace, and to ensure urban redevelopment. The most important measure is the Promotion Plan for Earthquake-resistant City Development Projects, because the implementation of such projects can reduce the damage in Tokyo (Pictorial 4-2). The Preparedness Plan for Urban Reconstruction is one of the new measures that was established after the Kobe Earthquake.
著者
Shinya WATANABE Jumpei ITO Takuya BABA Takahiro HIRATSUKA Kyohei KUSE Haruyo OCHI Yukari ANAI Masaharu HISASUE Hajime TSUJIMOTO Kazuo NISHIGAKI
出版者
公益社団法人 日本獣医学会
雑誌
Journal of Veterinary Medical Science (ISSN:09167250)
巻号頁・発行日
pp.13-0344, (Released:2013-12-09)
被引用文献数
1 3

Feline leukemia virus (FeLV) induces neoplastic and non-neoplastic diseases in cats. The transduction of cellular genes by FeLV is sometimes observed and associated with neoplastic diseases including lymphoma and sarcoma. Here, we report the first natural case of feline Notch2 transduction by FeLV in an infected cat with multicentric lymphoma and hypercalcemia. We cloned recombinant FeLVs harboring Notch2 in the env gene. Notch2 was able to activate expression of reporter gene, similar to what was previously reported in cats with experimental FeLV-induced thymic lymphoma. Our findings suggest that the transduction of Notch2 strongly correlates with FeLV-induced lymphoma.