著者

伊藤 吉弥 伊藤 伸泰 島田 尚

出版者

一般社団法人 日本物理学会

雑誌

日本物理学会講演概要集 67.2.2 (ISSN:21890803)

巻号頁・発行日

pp.257, 2012-08-24 (Released:2018-02-15)

著者

櫻井 義秀

出版者

日本宗教学会

雑誌

宗教研究 (ISSN:03873293)

巻号頁・発行日

vol.79, no.4, pp.1225-1227, 2006-03-30 (Released:2017-07-14)

著者

小川 陽子 島田 伸敬

出版者

横断型基幹科学技術研究団体連合(横幹連合)

雑誌

横幹連合コンファレンス予稿集 第8回横幹連合コンファレンス

巻号頁・発行日

pp.E-2-4, 2017 (Released:2018-02-18)

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Interfaces for people with severe motor impairments that enables them to interact with a healthy person and manipulates a wheelchair by extending the body motion ability through information equipment recently has been put to practical use. It is well known that tongue and gaze motion can remain even in much serious stage. It is a problem to assure the electric insulation of the device in oral cavity. In this research, we propose a pointing I/F using the intraoral image taken by a small camera for the endoscope available at low cost. Since the individual movement of the tongue is largely different according to disease condition and it may changes over time, a learning signal to the CNN is dynamically generated and adapted to ensure the invariant operative output range.

著者

紙田 路子 カミタ ミチコ Michiko Kamita

雑誌

岡山理科大学教育実践研究

巻号頁・発行日

vol.3, pp.23-36, 2019

著者

北村 暁夫

出版者

社会経済史学会

雑誌

社会経済史学 (ISSN:00380113)

巻号頁・発行日

vol.59, no.2, pp.291-319,343, 1993-07-25 (Released:2017-07-01)

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From the 1870s to the beginning of the First World War, numerous emigrants left Calabria, southern Italy, for the American countries. A large number of them were young single men who had worked in the agrarian sector in Italy. This article examinens the causes of the peasant emigration and its effects on rural areas in Calabria, using emigration statistics and contemporary surveys of agrarian inquiries. The emigration began in the northern part of the mountains of Calabria. Tha peasants of these areas traditionally participated in a subsistence economy supplemented by domestic industry and seasonal employment, especially in the plains, where the cereal latifondo was under cultivation. But when the decline in domestic industry and the consequent decrease in employment opportunities was accelerated by the agrarian crisis of the 1880s, many peasants were compelled to emigrate abroad as an alternative to traditional employment. Most emigrants eventually returned home and purchased a piece of lands. This disproves the contention that the emigration led to a general proletarialization of the peasants. While returnees with a lot of savings were able to become independent farmers, those who had not saved enough were forced to emigrate again, often permanently. In this way, the emigration charged the traditional subsistence economy and polarized the peasant structure of the area.

著者

金城 政信 三浦 雅典 折本 裕一 青木 百合子

出版者

公益社団法人 高分子学会

雑誌

高分子学会予稿集 第56回高分子学会年次大会

巻号頁・発行日

pp.878, 2007 (Released:2009-05-28)

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Siの(111)表面上への種々の金属原子の吸着およびそれに伴う表面再構成に関して吸着機構、被覆率における構造変化に着目し、モデルに対して理論的解析を行い、量子化学的見地からその考察を行った。

著者

堀下,歩美

出版者

不明

雑誌

日本教育社会学会大会発表要旨集録

巻号頁・発行日

no.64, 2012-10-25

著者

根岸 良充 大圃 研

出版者

一般社団法人 日本消化器内視鏡学会

雑誌

日本消化器内視鏡学会雑誌 (ISSN:03871207)

巻号頁・発行日

vol.64, no.4, pp.1025-1032, 2022 (Released:2022-04-20)

参考文献数

8

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近年の細径内視鏡とその周辺デバイスの進歩は目覚ましいものがある.元来は観察専用の内視鏡と認識されてきたが,状況によっては処置用として従来の内視鏡を超える優位性を擁する場合もある.われわれは1)鎮静剤使用を回避する,2)狭窄によって処置用内視鏡が使用できない,3)咽頭の病変へのアプローチ,の3つの場合において細径内視鏡を処置用として用いている.制約はありつつも,徐々に治療内視鏡としての可能性も持ち始めた細径内視鏡による内視鏡的粘膜下層剝離術の実際について詳述する.

著者

三浦 洋

出版者

北海道大学哲学会

雑誌

哲学 (ISSN:02872560)

巻号頁・発行日

vol.44, pp.231-239, 2008-02-29

著者

赤澤 健太郎

出版者

京都府立医科大学

雑誌

若手研究(B)

巻号頁・発行日

2012-04-01

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脳温度をMagnetic resonance imagingで非侵襲的に測定する方法のひとつとして、拡散強調画像から得られる側脳室内の脳脊髄液の拡散係数を利用する方法が近年提案されている。本研究では、この手法の安定性や、撮像条件・体温の違いによる影響を明らかにするために計画されたものである。健常成人の検討によって、この手法は安定的に脳室温度を計測することが可能であった。また撮像条件のうち、スライス厚は算出される温度に影響を与え、より薄いスライス厚のほうが望ましいという知見が得られた。また脳室温度は体温の影響を受けることも明らかとなった。

著者

柳場 由絵 豊岡 達士 王 瑞生 甲田 茂樹

出版者

日本毒性学会

雑誌

日本毒性学会学術年会 第47回日本毒性学会学術年会

巻号頁・発行日

pp.P-116, 2020 (Released:2020-09-09)

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【背景・目的】国内の化学工場において膀胱がんの発症が多数報告された事例では、芳香族アミン類が主に皮膚経路で吸収され、がんを誘発したと疑われている。現場で生じた膀胱がん症例の一部は、オルト-クロロアニリン(OCA)のばく露歴もあり、またインビトロ実験でこの物質は強い遺伝毒性が観察された。しかし、OCAについては、その経皮吸収に関する報告や定量的情報はなく、体内に入った後どの臓器に分布するかは不明である。そこで本研究では、ラットを用いて、OCA 経皮投与後のOCAの全身への分布・動態等について検討した。【方法】雄性Crl:CD(SD)ラット(7週齢)を用い、イソフルラン麻酔下で背部を剪毛、毛剃毛し、[14C]OCA経皮投与液を50mg/748kBq/4ml/kgの用量で塗布したリント布を用いて、8時間、24時間経皮投与した。投与終了後、リント布を剥離し、イソフルラン吸入麻酔下、炭酸ガスの過剰吸入により安楽死させ、全身オートラジオルミノグラムを作成した。投与後代謝ケージに収容し、採尿区間は投与開始後0~4時間、4~8時間、8~24時間の3時点とした。【結果・考察】投与後8時間、24時間の膀胱に放射活性が高く、投与したOCAのほとんどが膀胱へ移行していることが観察された。一方、肝臓や腎臓などの臓器への分布はほとんど観察されなかった。尿中排泄率からも投与後8~24時間の間で投与したOCA濃度の86%が排泄されており、これらの結果から、OCAは投与後、速やかに経皮吸収され、膀胱等に高濃度で移行する。また、24時間以内に投与濃度の大部分が尿中へと排泄され、肝臓や腎臓への蓄積が少ない物質であることが示唆される。

著者

古結 諒子

出版者

公益財団法人 史学会

雑誌

史学雑誌 (ISSN:00182478)

巻号頁・発行日

vol.120, no.9, pp.1493-1527, 2011-09-20 (Released:2017-12-01)

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The aim of the present article is to analyze the process by which Japan brought about a settlement in the first Sino-Japanese War (1894-1895) focusing on the settlement's interaction with both the changing power relations among the Great Powers and diplomatic trends of the Qing Dynasty, in order to show a clear transition taking place in Japan's diplomatic strategy at that time. The War has been pointed to as an event within a 19th century East Asia characterized by the coexistence of the traditional Chinese tribute system and modern treaty organizations that led to the final destruction of the former. However, the research to date has proceeded to discuss the process of Japan's conclusion of the War without sufficiently analyzing movements of the British-centered Great Powers, which supported the establishment of one single international order in East Asia. The main thrust of the research to date is the view that the diplomacy conducted by the Great Powers towards Japan constituted "external pressure" for Japan to wage war against the Qing Dynasty, but has neglected such aspects as Japan's international position and its influence to the Great Powers. For this reason, the present article attempts to analyze Japanese diplomacy within the interrelationship between the activities of the Great Powers and the Qing Dynasty from the standpoints of both Japan and Great Britain. Japanese diplomacy aiming at a conclusion to the War unsettled the leadership role of Great Britain which intended to maintain the cooperation among the Great Powers in East Asia. To begin with, Japan's announcing its intention to continue the War isolated Great Britain, who desired a quick end to the hostilities. Secondly, Japan's choice of the United States, who favored independent action among the Great Powers, as its intermediary with the Qing Dynasty not only elicited a request for negotiations, as Japan was winning on the battlefront, but also kept Great Britain out of the whole affair altogether. Finally, Japan's submission of a peace treaty draft brought to light the changes that had occurred in the interrelationships among the Great Powers. Under such conditions, Great Britain ended up agreeing with Russia, Germany and France in urging Japan to return the Liaodong Peninsula to the Qing Dynasty, in an attempt to reestablish its hegemony in the region. On the other hand, Japan's announcement to accept the advice enabled the exchange of the Shimonoseki Treaty ratification with the Qing Dynasty. Consequently, Japan was able to avoid the disadvantages of a prolonged war by settling the conflict. Japanese diplomacy up to the end of the War was not only directed at settling its dispute with the Qing Dynasty over the Korean Peninsula, but also simultaneously brought about a situation in which arrangements of cooperation among the Great Powers in East Asia centered around Great Britain fell into dysfunctionality.

著者

Moe Kidogawa Kei Yamasaki Kazuki Nemoto Kazuhiro Yatera

出版者

The Japanese Society of Internal Medicine

雑誌

Internal Medicine (ISSN:09182918)

巻号頁・発行日

vol.61, no.16, pp.2547-2549, 2022-08-15 (Released:2022-08-15)

参考文献数

1

被引用文献数

5

著者

Yuya Hagiwara Yoshiyuki Yamamoto Yuki Inagaki Reina Tomisaki Miki Tsuji Soma Fukuda Satoshi Fukuda Tsubasa Onoda Hirosumi Suzuki Yusuke Niisato Yoshitaka Tange Naoya Ikeda Keiichi Yamada Mariko Kobayashi Daisuke Akutsu Takeshi Yamada Toshikazu Moriwaki Toshiaki Narasaka Hideo Suzuki Kiichiro Tsuchiya

出版者

The Japanese Society of Internal Medicine

雑誌

Internal Medicine (ISSN:09182918)

巻号頁・発行日

vol.61, no.16, pp.2449-2455, 2022-08-15 (Released:2022-08-15)

参考文献数

43

被引用文献数

1

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Dihydropyrimidine dehydrogenase (DPD) deficiency induces severe adverse events in patients receiving fluoropyrimidines. We encountered a 64-year-old DPD-deficient man with a severe capecitabine-related gastrointestinal disorder. He received capecitabine-containing chemotherapy after rectal cancer resection. During the first course of chemotherapy, he developed severe diarrhea, a fever, and hematochezia. Endoscopy revealed mucosal shedding with bleeding throughout the gastrointestinal tract. DPD deficiency was suspected because he developed many severe adverse events of capecitabine early and was finally confirmed based on the finding of a low DPD activity level in peripheral blood mononuclear cells. After one month of intensive care, hemostasis and mucosal healing were noted, although his gastrointestinal function did not improve, and he had persistent nutritional management issues.

著者

Shiraki Shoki Shimomura Michitaka Kakui Keiichi

出版者

Sociedade Brasileira de Carcinologia

雑誌

Nauplius (ISSN:23582936)

巻号頁・発行日

vol.30, pp.e2022023, 2022

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We describe Kupellonura tamago sp. nov., collected from the North Pacific off the southern coast of the Boso Peninsula, Japan, at a depth of 445–407 m. This is the first record of Hyssuridae not only for Japan but also for the Temperate Northern Pacific ecoregion. Female K. tamago closely resembles Kupellonura gidgee Poore and Lew Ton, 1988 and Kupellonura indonesica Annisaqois and Wägele, 2021 in the shape of the uropodal exopod but differs from them in having a broader uropodal exopod (length/width ratio 1.47), a broader uropodal endopod (length/width ratio 1.64), and the telson margins smooth. We transfer Kupellonura flexibilis (Pasternak, 1982), originally described in Ananthura Barnard, 1925 but provisionally transferred to Kupellonura Barnard, 1925, to Anthelura Norman and Stebbing, 1886 in Antheluridae, as Anthelura flexibilis (Pasternak, 1982) comb. nov.

著者

Hiroyuki Seto Naoto Ishimaru Jun Ohnishi Yohei Kanzawa Takahiro Nakajima Toshio Shimokawa Yuichi Imanaka Saori Kinami

出版者

The Japanese Society of Internal Medicine

雑誌

Internal Medicine (ISSN:09182918)

巻号頁・発行日

vol.61, no.16, pp.2417-2426, 2022-08-15 (Released:2022-08-15)

参考文献数

31

被引用文献数

7

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Objective This study evaluated the effectiveness of a multidisciplinary team deprescribing intervention to reduce polypharmacy and potentially inappropriate medications (PIMs) in elderly orthopedic inpatients. Methods In this single-center retrospective observational study, orthopedic inpatients ≥75 years old and prescribed ≥6 different medications were enrolled as participants. Interventions comprised multidisciplinary team-led polypharmacy screening and suggestions regarding deprescribing any unnecessary medications during hospital stays. The primary outcome was reduction in the mean number of regular medicines and PIMs. Secondary outcomes included falls, delirium, and other adverse events during hospitalization as well as emergency department visits or unplanned hospital admissions within six months after discharge. Results After propensity score matching, 184 patients (intervention group, n=92; control group, n=92) were included in the analysis. The mean patient age was 83 years old. The mean number of prescribed medications and PIMs at admission were similar in both groups. The mean change in the number of regular medicines was -1.4 [standard deviation (SD), 2.3] in the intervention group and +0.2 (SD, 1.8) in the control group (p<0.001). The mean change in the number of PIMs was -0.5 (SD, 0.9) in the intervention group and +0.1 (SD, 0.8) in the control group (p<0.001). In-hospital adverse events other than falls and delirium were significantly less common in the deprescribing intervention group than in the control group. Conclusion Deprescribing intervention by our multidisciplinary team seems to have been effective in reducing the number of prescribed medicines and PIMs in elderly orthopedic inpatients, with some accompanying reduction in certain adverse events.

著者

和田 哲義

出版者

一般社団法人 表面技術協会

雑誌

表面技術 (ISSN:09151869)

巻号頁・発行日

vol.59, no.8, pp.495, 2008 (Released:2009-03-25)

参考文献数

16

被引用文献数

6 4

著者

Yusaku OHKUBO

出版者

Japan Association for Philosophy of Science

雑誌

Annals of the Japan Association for Philosophy of Science (ISSN:04530691)

巻号頁・発行日

vol.30, pp.23-41, 2021 (Released:2021-12-14)

参考文献数

44

被引用文献数

1

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The history of statistics is filled with many controversies, in which the prime focus has been the difference in the “interpretation of probability” between Frequentist and Bayesian theories. Many philosophical arguments have been elaborated to examine the problems of both theories based on this dichotomized view of statistics, including the well-known stopping-rule problem and the catch-all hypothesis problem. However, there are also several “hybrid” approaches in theory, practice, and philosophical analysis. This poses many fundamental questions. This paper reviews three cases and argues that the interpretation problem of probability is insufficient to begin a philosophical analysis of the current issues in the field of statistics. A novel viewpoint is proposed to examine the relationship between the stopping-rule problem and the catch-all hypothesis problem.

著者

川上 和人 鈴木 創 堀越 和夫 川口 大朗

出版者

首都大学東京小笠原研究委員会

雑誌

小笠原研究 = Ogasawara research (ISSN:03868176)

巻号頁・発行日

no.44, pp.217-250, 2018-07

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南硫黄島の鳥類相の現状を明らかにするため、2017年6月14日~27日の期間に現地で調査を行った。その結果、過去に繁殖が確認されていた各種鳥類の生息が確認され、いずれの種についても特に大きな個体数の変動はないものと考えられた。ただし、コルと山頂の間では過去10年で高茎草本を中心とした密度の高いブッシュが発達しており、このような場所ではミズナギドリ科、ウミツバメ科の営巣が減少していた。セグロミズナギドリ Puffinus bannermaniは2007年の調査では山頂付近でのみ確認されていたが、今回の調査から標高300mの崩落地内の岩石地でも営巣していると考えられた。山頂周辺ではオーストンウミツバメ Oceanodroma tristramiの巣立ち前後の雛や成鳥が見つかり、南硫黄島における初めての繁殖の証拠となった。海鳥の営巣は、海岸部では植生が沿岸部に認められる場所において、山上部では森林が発達した場所で密度が高い傾向があった。UAVによる調査で南部の海岸に面した崖上ではアカアシカツオドリ Sula sulaの集団繁殖地が国内で初めて確認された。同じくUAVによる調査で北部の崖上のモクビャクコウ Crossostephium chinense群落において地上に下りている複数のクロアジサシ Anous stolidusが確認された。ここでは証拠は得られなかったものの営巣している可能性があると考えられた。アナドリ Bulweria bulwerii、カツオドリ Sula leucogaster、アカオネッタイチョウ Phaethon rubricaudaでは、羽毛にシンクリノイガ Cenchrus echinatus及びナハカノコソウ Boerhavia diffusaの果実を付着させた個体が見られ、これらの海鳥が種子散布者となっていることが示唆された。

著者

山口晋平 著

出版者

法学書院

巻号頁・発行日

1952