著者
宮坂 賢一
出版者
日経BP社
雑誌
日経トップリーダー
巻号頁・発行日
no.322, pp.48-51, 2011-07

カイゼン指導のPEC産業教育センター所長。トヨタ生産方式の創始者、大野耐一氏に師事、キヤノンやソニーをはじめ主に製造現場のカイゼンを手掛ける。
出版者
巻号頁・発行日
vol.154 信州牧嶋城図,
著者
Sandi SUFIANDI Hiromichi OBARA Huai-Che HSU Shin ENOSAWA Naoto MATSUNO Hiroshi MIZUNUMA
出版者
一般社団法人 日本機械学会
雑誌
Journal of Biomechanical Science and Engineering (ISSN:18809863)
巻号頁・発行日
pp.17-00325, (Released:2017-10-12)
参考文献数
33
被引用文献数
5

A sufficient number of functional live hepatocytes delivered to a recipient is necessary for cell therapy. Preventing cell viability loss during the cell injection process is important to improve the clinical outcomes of hepatocyte transplantation. The critical location of cell viability loss is important to identify the causal relationship between the viability loss and cell injection process. In this study, the critical location of cell viability loss was determined experimentally in a rectangular microchannel by microscopic high-speed camera observations. Live hepatocyte distributions were investigated upstream and downstream, and measured on three planes, top, center, and bottom, under horizontally or vertically supplied conditions of the syringe orientation. Sedimented and uniform dispersion conditions of the live hepatocyte distribution at upstream of the microchannel were classified according to observations at horizontal and vertical syringe orientations, respectively. Higher hepatocyte viability loss was found under the sedimented condition. The results suggested that the critical location of hepatocyte viability loss was on the bottom plane of the microchannel. Furthermore, physical causes of the hepatocyte viability loss were found by micro-scale observations of the cell velocity and diameter during the cell injection process. This information may contribute to development of a guideline for the cell injection process to improve hepatocyte transplantation.
著者
亀田 隆夫 高橋 辰宏 小山 清人
出版者
The Japan Society of Polymer Processing
雑誌
成形加工 (ISSN:09154027)
巻号頁・発行日
vol.17, no.8, pp.571-579, 2005-08-20
参考文献数
15
被引用文献数
1

The precise measurement of three dimensional shrinkage at different locations within molded parts is seldom reported. In this research, we compared the measured shrinkage (relating the difference between the dimensions of the metal mold and the resultant molded plastic parts) with calculations based on PVT measurements for parts made from AS and ABS resins. With increasing packing pressure, the shrinkage was minimized in the normal direction (ND) more than in the melt flow (MF) and transverse (TD) directions. The ND shrinkage was proportional to the volume shrinkage, while those of the other directions were proportional to less than the 1/3 power of volume shrinkage. The TD shrinkage was larger than the MD shrinkage. With increasing packing pressure, the gate seal time increased for ABS, but hardly changed for AS. The molecular orientation, obtained from birefringence measurements, increased with packing pressure.
著者
東 和男 山本 泰 好井 久雄
出版者
公益財団法人 日本醸造協会
雑誌
日本釀造協會雜誌 (ISSN:0369416X)
巻号頁・発行日
vol.82, no.2, pp.121-124, 1987-02-15 (Released:2011-11-04)
参考文献数
4
被引用文献数
1 1

電子顕微鏡により耐塩性酵母Zygosacch. rouxiiの微細構造を観察し, 次の結果を得た。1) 2%過マンガン酸カリウムで24時間固定した無塩及び含塩下培養の対照酵母Sacch. sakeは完全に過固定になったが, 同固定条件では耐塩性酵母はやや過固定にとどまった。一方, 両酵母のプロトプラストは過マンガン酸カリウムより固定能の弱い2%四酸化オスミウムによって適切に固定された。上記のことは, 耐塩性酵母の細胞壁が細胞内への固定液の透過を抑制していることを示しており, 細胞壁は食塩の細胞内への透過に対する防壁となることが推定される。2)細胞壁の厚さは,対照酵母では含塩下培養で薄くなる傾向が認められたが, 耐塩性酵母では無塩と含塩下培養の間に差異が認められなかった。3)耐塩性酵母において無塩培養でミトコンドリアが良好に発達したほかは, 耐塩性酵母対照酵母のいずれにおいても食塩は細胞質構造に影響を及ぼさないことが観察された。
著者
亀田 隆夫 高橋 辰宏 小山 清人
出版者
The Japan Society of Polymer Processing
雑誌
成形加工 (ISSN:09154027)
巻号頁・発行日
vol.17, no.5, pp.342-348, 2005-05-20
参考文献数
15
被引用文献数
1 1

The size of the dependence of the shrinkage anisotropy in different locations of injection molded parts is not frequently reported (shrinkage calculated by comparing the actual plastic parts to the metal mold, while anisotropy refers to differences in the melt flow (MD) and the transverse (TD) directions). In this study, the effects of packing pressure (from 20 to 100MPa) in the injection molding process on the shrinkage anisotropy at two positions in a molded part were investigated in two ABS resins. The shrinkage anisotropy decreased as a function of packing pressure at both locations, although at different rates. It was found that the shrinkage anisotropy at these two positions was quite similar at around 60MPa. It was also found that the screw head moved forward (backward) at pressures higher (lower) than 60MPa. At a packing pressure of 60MPa the screw head position was almost constant during the packing process in a plunger type injection molding machine where the polymer melt can hardly flow backwards.<br>In order to get further insight into the causes of the shrinkage anisotropy, birefringence measurements were performed with a transparent ABS resin. The measured birefringence at the two locations of the injection molded part were in good agreement with the respective shrinkage anisotropy values. Moreover, the packing pressure dependence seen in the shrinkage anisotropy was found to be similar for that of birefringence. It was demonstrated that a difference in molecular orientation in the two directions (MD and TD), caused the shrinkage anisotropy, and that the ratio of molecular orientation difference becomes almost identical at the two locations at around 60MPa of packing pressure.
出版者
巻号頁・発行日
vol.第209冊,
著者
山本 長紀
出版者
木更津工業高等専門学校
雑誌
若手研究(B)
巻号頁・発行日
2017-04-01

本研究課題である「高専における語彙学習を促進するタスクベースカリキュラムの開発」を目的とし、平成29年度は「タスクの理論的枠組の提唱」を目標に文献研究や国内外の調査を行った。語彙学習に関しては、瀬川・山本・岩崎・荒木・小澤(2018)などの実証研究を行った。タスクの理論的枠組みに関しては、藤田(2017)や杉浦(2009)のように高専におけるニーズ分析を行う必要性を本研究に組み込むことを確認し、次年度実施するよう計画している。当初計画に加えて研究推進のための手法が増えたものの、本研究は概ね順調に進行している。
著者
小笠原 匡 多田野 寛人 櫻井 鉄也 伊藤 祥司
出版者
一般社団法人 日本応用数理学会
雑誌
日本応用数理学会論文誌 (ISSN:09172246)
巻号頁・発行日
vol.14, no.3, pp.193-205, 2004
参考文献数
8
被引用文献数
1

We consider a method to solve several shifted linear systems (A+σl)x = b with shift parameter σ. Krylov subspace for shifted linear systems is not depend on the parameter σ, therefore we can solve several shifted linear systems simultaneously without generating Krylov subspace for each parameter cr. In this paper, we show that shifted linear systems appear in an eigensolver using numerical integration. We applied Krylov subspace methods for shifted linear systems in this eigensolver. We have also presented some numerical examples illustrate the efficiency of the method.

1 0 0 0 OA 消息往来

出版者
鶴屋喜右衛門
巻号頁・発行日
1834
著者
藤井 敦
出版者
一般社団法人情報処理学会
雑誌
情報処理学会研究報告情報学基礎(FI) (ISSN:09196072)
巻号頁・発行日
vol.2008, no.56, pp.9-15, 2008-06-12
被引用文献数
1

日本では年間約 40 万件の特許が出願され,多様な専門分野に関する知識が蓄積されている.特許情報に内在する人間の英知を体系化し,活用することができれば,学術や産業において価値がある.特許情報には高度な技術に関する新語や専門用語が多く含まれており,World Wide Web では見つけることができない専門用語も含まれている.本研究は,15 年分の日本公開特許公報テキストから約 190 万語の見出し語を含む用語辞典的なコンテンツを自動構築した.さらに,当コンテンツを検索するためのシステムを開発した.本システムは,見出し語の説明を検索することが可能である.また,関連語,同義語,自然言語文,関連語グラフによって,用語情報を多面的に調査することが可能である.In Japan, approximately 400,000 patent applications are submitted every year, which contain knowledge related to various technical fields. Organizing and utilizing human intelligence latent in patent information are valuable from scientific and industrial points of view. Patent information contains new words and technical terms associated with high-technology, and a number of these terms cannot be found on the World Wide Web. We produced an encyclopedic dictionary content from 15 years of Japanese unexamined patent applications, in which approximately 1.9 million headwords are indexed. We also implemented a search system to utilize this content. Users can search for descriptions of a technical term. Users can also research technical terms by submitting, related terms, synonyms, and natural language questions and viewing related-term maps.