著者

伊藤 幸成

出版者

公益社団法人 日本農芸化学会

雑誌

化学と生物 (ISSN:0453073X)

巻号頁・発行日

vol.50, no.6, pp.393, 2012-06-01 (Released:2013-06-01)

著者

Kiichiro Totani

出版者

FCCA(Forum: Carbohydrates Coming of Age)

雑誌

Trends in Glycoscience and Glycotechnology (ISSN:09157352)

巻号頁・発行日

vol.31, no.181, pp.SE59-SE60, 2019-07-25 (Released:2019-07-25)

参考文献数

12

被引用文献数

1

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Glycoprotein quality control is regulated by high-mannose glycans on the glycoprotein as signals. We found that the quality control mechanism is complementarily regulated by secondary factors other than glycan recognition through our glycoprobe-based analysis. We revealed that most related glycan-recognizing proteins discriminate the aglycon state difference of the substrate glycoprotein to regulate activity. We also found that the upstream of the glycan processing is accelerated and the downstream is decelerated under the molecular crowding conditions mimicking the inside of the cell. Furthermore, the effect of diseases such as obesity, type 2 diabetes, and osteoporosis on the operation status of glycoprotein quality control was clarified.

著者

佐川 友里香 萩原 将文

出版者

Japan Society of Kansei Engineering

雑誌

日本感性工学会論文誌 (ISSN:18840833)

巻号頁・発行日

pp.TJSKE-D-17-00085, (Released:2018-02-27)

参考文献数

27

被引用文献数

2

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In this paper, we propose an attribute added face image generation system using Deep Convolutional Generative Adversarial Networks (DCGANs). Convolutional Neural Networks (CNNs) can extract important features of an image and attain high precision in image classification tasks. In the proposed system, image features are extracted using CNNs, and attribute features added to image features, and attributes added images are generated by DCGANs. Specifically, we use the attributes of “smile” and “male”, and work on a task of generating smile images from non-smile images, and a task of generating male images from women images. Since the training of the proposed system requires image pairs including with and without attributes, we use two extraction methods using attribute label and cosine similarity. Attribute features are defined as the averaged difference between image features with and without attributes. We performed two kinds of evaluation experiments, and excellent characteristics were obtained.

著者

田村 元 塩原 健次郎

出版者

一般社団法人 溶接学会

雑誌

溶接学会誌 (ISSN:00214787)

巻号頁・発行日

vol.17, no.5, pp.182-188, 1948 (Released:2009-06-12)

参考文献数

5

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鑄鐵瓦斯熔接の際熔着鐵の地をFerriteを多くし,黒鉛を可及的に多く出るものを得る目的で本研究を行つた・第一報にては(Si+Al)が3,4,5,7%なる場合の試驗を行つた結果(1)(Al+Si)=3.0~4.3%が熔接棒を作製し易い.(2)Al2%以上となると熔接操作が難しくなる.(3)(Al+Si)%が増す程黒鉛が多くなり且つ形状は細く一樣となる.(4)Alを加へると機械加工は母材と同樣で困難ではない.(5)母材との「なじみ」は何れも良好である.なることが判つた.

著者

高橋 登

出版者

日本コミュニケーション障害学会

雑誌

コミュニケーション障害学 (ISSN:13478451)

巻号頁・発行日

vol.23, no.2, pp.118-125, 2006-08-31 (Released:2010-04-21)

参考文献数

31

被引用文献数

1

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本論文では,学童期の語彙獲得の過程について検討した.子ども達は,学童期も幼児期に劣らず多くの語彙を日々獲得している.ただし,そのプロセスは幼児期とは大きく異なる.第1に,子どもの語彙理解は時間をかけて深く,また広くなっていく.第2に,一定の語彙を獲得すると,その要素の知識に基づいて,それを組み合わせた新しい語の意味を推測によって知ることができるようになる.そして第3に,学校での授業だけでなく,たとえ1日あたりの読書時間はささやかなものであっても,それが積み重なることで子ども達は多くの言葉に接し,文脈から新たな言葉の意味を身に付けていく.

著者

Michael H. SMOLENSKY Alain E. REINBERG Frida Marina FISCHER

出版者

National Institute of Occupational Safety and Health

雑誌

Industrial Health (ISSN:00198366)

巻号頁・発行日

vol.57, no.2, pp.158-174, 2019 (Released:2019-04-01)

参考文献数

132

被引用文献数

1 15

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The circadian time structure (CTS) has long been the subject of research in occupational medicine, but not to industrial toxicology, including methods of setting threshold limit values (TLVs) and employee biological monitoring. Numerous animal and human investigations document vulnerability to chemical, contagion, and other xenobiotics varies according to the circadian time of encounter. Permanent and rotating nightshift personnel are exposed to industrial contaminants in the same or higher concentration as dayshift personnel, and because of incomplete CTS adjustment to night work, contact with contaminants occurs during a different biological time than day workers. Thus, the amount of protection afforded by certain TLVs, especially for employees of high-risk settings who work night and other nonstandard shift schedules, might be inadequate. The CTS seems additionally germane to procedures of employee biological monitoring in that high-amplitude 24 h rhythms in biomarkers indicative of xenobiotic exposure may result in misjudgment of health risks when data are not gathered in sufficient frequency over time and properly interpreted. Biological reference values time-qualified for their rhythmic variation, currently of interest to laboratory medicine practice, are seemingly important to industrial medicine as circadian time and work-shift specific biological exposure indices to improve surveillance of personnel, particularly those working nonstandard shift schedules.

著者

本橋 圀司 細川 明

出版者

The Japanese Society of Agricultural Machinery and Food Engineers

雑誌

農業機械学会誌 (ISSN:02852543)

巻号頁・発行日

vol.37, no.4, pp.694-698, 1976 (Released:2010-04-30)

参考文献数

14

著者

Kazuo Tsuchiya Masato Karayama Taichi Sato Hideki Yasui Hironao Hozumi Yuzo Suzuki Kazuki Furuhashi Noriyuki Enomoto Tomoyuki Fujisawa Yutaro Nakamura Naoki Inui Haruhiko Sugimura Hideo Yasuda Takafumi Suda

出版者

The Japanese Society of Internal Medicine

雑誌

Internal Medicine (ISSN:09182918)

巻号頁・発行日

pp.3004-19, (Released:2019-07-22)

参考文献数

35

被引用文献数

7

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A 71-year-old woman with abnormal pulmonary shadows and multiple enlarged thoracic lymph nodes was diagnosed with stage IIB lung adenocarcinoma, pulmonary sarcoidosis, and sarcoidosis-associated lymphadenopathy after biopsies from multiple organ sites. She also had rapidly progressive renal dysfunction, microhematuria, and high myeloperoxidase anti-neutrophil cytoplasmic antibody (MPO-ANCA) concentrations. A renal biopsy revealed granulomatous tubulointerstitial nephritis and necrotizing glomerulonephritis with crescent formation. She was diagnosed with nephritis caused by both sarcoidosis and ANCA-associated vasculitis. Oral prednisolone was administered to treat her nephritis, resulting in improvement in both her renal dysfunction and her sarcoidosis-associated lymphadenopathy.

著者

香月 法子

出版者

日本宗教学会

雑誌

宗教研究 (ISSN:03873293)

巻号頁・発行日

vol.87, no.Suppl, pp.484-486, 2014-03-30 (Released:2017-07-14)

著者

越野 和之

出版者

一般社団法人 日本教育学会

雑誌

教育学研究 (ISSN:03873161)

巻号頁・発行日

vol.83, no.2, pp.220-222, 2016 (Released:2016-08-06)

著者

鈴木 栄幸 舟生 日出男

出版者

一般社団法人 日本科学教育学会

雑誌

科学教育研究 (ISSN:03864553)

巻号頁・発行日

vol.26, no.1, pp.42-55, 2002-03-10 (Released:2017-06-30)

参考文献数

8

被引用文献数

4

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In this paper, we focus on the "Question-Answer" function of SOUTO ; a hypermedia authoring system, and classroom activities where learners make hypermedia compositions with SOUTO and discuss their compositions with the function mentioned above. Field tests of the system reveal that ; 1 . The Question-Answer function reconfigures social relationships in the classroom and thus creates a foundation for collaborative learning, 2 . The Question-Answer function creates a field of informal talk, 3 . The SOUTO system provides a foundation on which both formal and informal talks are constituted and woven together, and thus, enables transition between them. Based on these findings, we suggest that educational systems should be designed as mediators which hybridize school-like activities and non-school-like activities.

著者

豊島 吉則

出版者

日本第四紀学会

雑誌

第四紀研究 (ISSN:04182642)

巻号頁・発行日

vol.14, no.4, pp.221-230, 1975-12-31 (Released:2009-08-21)

参考文献数

16

被引用文献数

5 5

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Most of the San' in sand dunes are those of‘dune ridge’(dune on the beach ridge) type which was proposed in the essay of D.W. JOHNSON (1919). So called‘old dunes’are not the simple dunes but old dunes on the old beach ridge and beach berm which formed at +25m former sea level. These old sand deposits were covered with brown soil and dissected and excavated by the wind and stream. The old sand dunes were formed on these marine deposits and brown soil and then covered with red soil, grey clay and Daisen middle volcanic ashes. New sand dunes which formed in Holocene are well developed everywhere along sandy coast. In Kyuhin penninsula three curved beach ridge groups are clearly recognised on which three new sand dunes were developed. These new dune ridges are widespread and their zonal or linear pattern are useful for analyzing dune formation history. New dune Ia and Ib are discovered under the black sand a and b respectively along inland part of the dune pattern. The New dune IIa, IIb and IIc are found near the present shoreline. These new dunes seem to have been formed after Jomon, Heian and very recent transgressions, respectively.

著者

高岡 祥子

出版者

日本動物心理学会

雑誌

動物心理学研究 (ISSN:09168419)

巻号頁・発行日

pp.0907110054, (Released:2009-07-17)

参考文献数

46

被引用文献数

1 1

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Recent researches have shown that dogs (Canis familiaris) possess a number of social cognitive abilities and communicate with humans in unique ways. Several researches suggest that dogs do not only use the overt features of humans (e.g., pointing, gaze) to find a hidden food in an object choice task, but also recognize the covert aspects of humans (e.g., knowledge) to predict the actions of them. This paper reviews evidence showing such excellent social cognition in dogs. Several comparisons between wolves and dogs suggest that human-like social skills by dogs have evolved as a by-product of domestication. Besides, some researchers argue the possibility of acquisition of similar social skills between dogs and humans through convergent cognitive evolution, which enabled them to communicate. The study of social cognitive skills in dogs will broaden our understanding of comparative social cognition.

著者

菅 裕

出版者

日本音楽教育学会

雑誌

音楽教育学 (ISSN:02896907)

巻号頁・発行日

vol.39, no.1, pp.13-24, 2009 (Released:2017-08-08)

参考文献数

17

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本研究の目的は, 経験年数の異なる吹奏楽指導者の演奏診断および演奏指導の方法, さらにその背後にある指導観の違いについて分析することにより, 演奏指導力の熟達化を特徴づける要因について考察することにある。中学生による吹奏楽合奏VTR視聴中の各指導者の内言発話および各指導者自身による合奏指導の内容のカテゴリー分析とPAC分析に基づくインタビューの結果, 経験年数が比較的短い4名の指導者が「正確な演奏の追求」を重視しているのに対し, 経験年数の最も長い指導者は, 楽曲構造についての演奏者の総合的な音楽理解を促進し, それに基づく自発的・積極的表現姿勢を引き出すことを重視していた。また経験年数が比較的短い指導者の中心的指導方法が「指示」であるのに対し, 経験年数の長い指導者の場合は「指示」の割合が相対的に低くなり「モデリング」「理論的説明」「メタファー」「質問」の使用頻度が高かった。

著者

Tadashi Satoh

出版者

FCCA(Forum: Carbohydrates Coming of Age)

雑誌

Trends in Glycoscience and Glycotechnology (ISSN:09157352)

巻号頁・発行日

vol.31, no.181, pp.SE69-SE70, 2019-07-25 (Released:2019-07-25)

参考文献数

5

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N-glycan acts as quality control tag for determination of intracellular glycoprotein fates. I have demonstrated the structural basis for N-glycan-dependent determination of glycoprotein fates at atomic level by using several biophysical methods including X-ray crystallography. In 2012, I received a JSCR young science award entitled “Structural biology study of intracellular lectins involved in glycoprotein transport and degradation.” In recent years, I have focused on ER glycoprotein folding system, i.e., calnexin/calreticulin cycle, and successfully determined 3D structures of ER glucosidase II (GII) and UDP-glucose:glycoprotein glucosyltransferase (UGGT), which are respectively responsible for glucose trimming and attachment, providing structural insights into ER quality control mediated by glucose tagging.

著者

Nobuyuki Ogura David Leonides T. Yap Kenichi Tanoue

出版者

ARCHITECTURAL INSTITUTE OF JAPAN (AIJ), ARCHITECTURAL INSTITUTE OF KOREA (AIK), ARCHITECTURAL SOCIETY OF CHINA (ASC)

雑誌

Journal of Asian Architecture and Building Engineering (ISSN:13467581)

巻号頁・発行日

vol.1, no.2, pp.2_233-238, 2002 (Released:2003-06-17)

参考文献数

15

被引用文献数

4

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The present paper attempts to clarify the characteristics of the modern Filipino style which was introduced by leading architects following World War II. The primary questions examined herein are as follows: 1) what is the background of the quest for Filipino style, 2) what are the sources of design connected with this tradition, and 3) how modernists designed structures according to their own design methods. Among leading Filipino architects, Leandro V. Locsin and Francisco Manosa are outstanding figures who embraced the possibility of a Filipino style that was based on their culture and gave clear direction to modern design.

著者

長谷 晃広 相田 潤 坪谷 透 小山 史穂子 松山 祐輔 三浦 宏子 小坂 健

出版者

一般社団法人 口腔衛生学会

雑誌

口腔衛生学会雑誌 (ISSN:00232831)

巻号頁・発行日

vol.65, no.3, pp.276-282, 2015-04-30 (Released:2018-04-13)

参考文献数

11

被引用文献数

1

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近年,歯学部において「将来設計に関する教育(以下,キャリア教育)」が実施されているが,これまでその効果を全国的に検証した研究はほとんど報告されていない.そこで本研究は,全国の研修歯科医を対象として 1)将来設計およびキャリア教育受講の実態把握とその関連性の検討ならびに,2)具体的な志望進路の実態把握を目的とした.2,323名に対し自記式調査票を郵送し1,590名から回答を得た(回収率68.4%).主要な変数に欠損のない1,428名のデータで解析を行った.「将来設計を描けている」と回答した者は212名(14.8%)であった.将来設計を描けていると回答する者の割合はキャリア教育受講経験を有する群で高く(p=0.015),性別,年齢,婚姻状態,出身大学,親の職業を調整したうえでもその関連は支持された(prevalence ratio=1.18, 95%信頼区間=1.08-1.29, p<0.001).希望する進路の最多回答は,研修直後および研修修了5年後では診療所勤務(570名:39.9%および723名:50.6%),研修修了10年後では診療所の開業(705名:49.4%)であった.本研究より,キャリア教育は将来設計を描くにあたり有効である可能性が示唆され,約半数の研修歯科医が10年後以降には歯科診療所を開業したいと考えていることが明らかになった.

出版者

公益社団法人 日本農芸化学会

雑誌

化学と生物 (ISSN:0453073X)

巻号頁・発行日

vol.15, no.11, pp.722-724, 1977-11-25 (Released:2009-05-25)

著者

松田 聡

出版者

美学会

雑誌

美学 (ISSN:05200962)

巻号頁・発行日

vol.54, no.2, pp.70-83, 2003-09-30 (Released:2017-05-22)

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In February, 1786, the Emperor Joseph II gave a feast at Schonbrunn Palace. On this occasion, Der Schauspieldirektor, a comedy with music by Mozart, was given its first performance, together with Salieri's opera buffa Prima la musica e poi le parole. So it has long been widely accepted that the two composers' music competed with each other in the feast. But, in fact. Der Schauspieldirektor is a unique stage work, of which the first half is formed as a German Play and the latter as a Singspiel. This fact necessitates reconsideration of the "competition". From October, 1785, three genres of stage work, German Play, Singspiel and Italian Opera, were performed at Viennese court theatres, so the feast can be regarded as an epitome of this system of performance in operation. This system marks an epoch in the Viennese performance history of opera, because, till then, it had never occurred that both the Italian Opera and the Singspiel were performed at court theatres in the same period. The two works performed in the feast share the same subject, that is the rivalry and the harmony between the different genres, and through it, the Emperor demonstrated his new idea to treat both German and Italian theatrical genres equally.

著者

Amih SAGAN 長嶋 雲兵 寺前 裕之 長岡 伸一

出版者

日本コンピュータ化学会

雑誌

Journal of Computer Chemistry, Japan (ISSN:13471767)

巻号頁・発行日

vol.10, no.2, pp.75-77, 2011 (Released:2011-09-05)

参考文献数

8

被引用文献数

3 1

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初心者向けの量子化学の教科書には異核2原子分子の例としてLiHが取り上げられ,その分子軌道エネルギー準位図が示されている.その図ではLiHの2σ軌道のエネルギーがH原子の1s軌道よりも低い軌道エネルギーを持つことが示されているが,非経験的ハートリーフォック法を用いるとそれが再現できない.本ノートでは非経験的ハートリーフォック法で描かれるLiHの軌道エネルギー準位図を示す.用いた基底関数は6-311++G**である.非経験的ハートリーフォック計算から得られる図では,2σ軌道の軌道エネルギー(-8.18749 eV)はLiの2s (-5.3392 eV)より低く,安定化しているが,Hの1s (-13.60 eV)より高く,不安定化している.2σ軌道はおもにHの1s軌道で構成されており,Hの形式電荷は約-0.4であり,H周辺にLiの2s電子が過剰にあるため,Hの1s軌道から見ると相対的に電子間反発で不安定化する.