著者
鈴木 将司 宮内 俊幸 水野 佑哉 石川 徳久
出版者
公益社団法人 日本分析化学会
雑誌
分析化学 (ISSN:05251931)
巻号頁・発行日
vol.65, no.1, pp.33-38, 2016-01-05 (Released:2016-02-06)
参考文献数
21

ケナフ中のセルロースを濃塩酸で加水分解し,生成した還元性末端基(アルデヒド基)を過マンガン酸カリウムで酸化することによってカルボキシル基を有する弱酸性型陽イオン交換体を得た.このイオン交換体の交換容量は2.80 Cu(II) meq g-1– Rと高く,吸着速度も速く30分以内で吸着平衡に達した.また,金属イオンの吸着はpH=2.5以上から始まり,従来のカルボキシル基型イオン交換体と比較し低pH領域からの吸着が認められた.カラム法を用いて本交換体に対する銅イオン及び白金族金属イオンの吸着挙動を調べたところ,銅(II),ルテニウム(III),ロジウム(III)及びパラジウム(II)は吸着するが,他の白金族金属イオン,すなわちイリジウム(III),オスニウム(IV)及び白金(IV)は吸着しない.また,カラム内に保持された白金族金属イオンは塩酸溶離液でCu(II) – Pd(II) – Ru(III)及びCu(II) – Rh(III) – Ru(III)の三元分離ができた.さらにノートパソコン基板を王水処理し,その中に存在する銅(II)及び白金族金属イオンの回収について検討した.
著者
Ichiro Yamato Yoshimi Kakinuma Takeshi Murata
出版者
一般社団法人 日本生物物理学会
雑誌
Biophysics and Physicobiology (ISSN:21894779)
巻号頁・発行日
vol.13, pp.37-44, 2016 (Released:2016-02-27)
参考文献数
39
被引用文献数
8

Among the many types of bioenergy-transducing machineries, F- and V-ATPases are unique bio- and nano-molecular rotary motors. The rotational catalysis of F1-ATPase has been investigated in detail, and molecular mechanisms have been proposed based on the crystal structures of the complex and on extensive single-molecule rotational observations. Recently, we obtained crystal structures of bacterial V1-ATPase (A3B3 and A3B3DF complexes) in the presence and absence of nucleotides. Based on these new structures, we present a novel model for the rotational catalysis mechanism of V1-ATPase, which is different from that of F1-ATPases.
著者
榊原 良太 北原 瑞穂
出版者
公益社団法人 日本心理学会
雑誌
心理学研究 (ISSN:00215236)
巻号頁・発行日
pp.87.15302, (Released:2016-03-10)
参考文献数
43
被引用文献数
1 30

This study aimed to investigate the relations between CERQ and depression, and anxiety, and also aimed to reveal the characteristics of a Japanese sample through meta-analysis. The results showed that self-blame, acceptance, rumination, catastrophizing, and blaming others had significantly positive correlations with both depression and anxiety, whereas positive refocusing, refocus on planning, positive reappraisal, and putting into perspective had significantly negative correlations with both variables. Moreover, when comparing the correlation coefficients of the Japanese samples and the combined value, correlations between depression and positive reappraisal were significantly larger than the combined value. On the other hand, regarding the correlation coefficients of depression and putting into perspective, the combined value was larger than the value of Japanese samples. In addition, compared to the combined value, the Japanese sample’s positive correlation between anxiety and rumination, and negative correlation between anxiety and positive reappraisal were larger.
著者
Chiara Bernelli Kunihiro Shimamura Kenichi Komukai Davide Capodanno Francesco Saia Roberto Garbo Francesco Burzotta Vasile Sirbu Micol Coccato Gianluca Campo Luigi Vignali Hirosada Yamamoto Giampaolo Niccoli Elena Ladich Giuseppe Biondi-Zoccai Giulio Guagliumi
出版者
日本循環器学会
雑誌
Circulation Journal (ISSN:13469843)
巻号頁・発行日
pp.CJ-15-1140, (Released:2016-02-08)
参考文献数
23
被引用文献数
1 5

Background:The role of culprit plaque and related atherothrombotic components on incomplete stent apposition (ISA) occurrence after primary percutaneous coronary intervention (p-PCI) is unknown.Methods and Results:ST-segment elevation myocardial infarction (STEMI) patients undergoing p-PCI with an everolimus-eluting stent were prospectively investigated with optical coherence tomography (OCT) of the infarct-related artery before, after stenting and at 9 months. OCT data, aspirated thrombus and serum inflammatory biomarkers were analyzed. 114 patients with 114 lesions were evaluated. Acute ISA occurred in 82 lesions (71.9%), preferentially in larger vessels with a median area of 0.2 mm2. The presence of thrombus before stent implantation (odds ratio (OR) 5.5, 95% confidence interval (CI) [1.1–26.9], P=0.04) and the lipid content in the target segment (OR 1.3, 95% CI [1.0–1.5], P=0.04) independently predicted acute ISA. At 9-month follow-up, ISA persisted in 46 lesions (56.1%). The volume of acute ISA significantly predicted persistent ISA (OR 1.3, 95% CI [1.1–1.5], P=0.01). Late-acquired ISA occurred in 39 lesions (34.2%) with a median area of 0.3 mm2. Red/mixed thrombus before stent implantation (OR 3.7, 95% CI [1.0–13.3], P=0.05) and length of the underlying ruptured plaque (OR 1.7, 95% CI [1.1–2.8] P=0.02) were independently associated with late-acquired ISA.Conclusions:In STEMI patients, culprit plaque and atherothrombotic components of the infarct-related artery significantly contribute to the onset of acute and late ISA. ISA persistence at follow-up depends on the initial volume of acute ISA.
著者
刑部 義美 高橋 愛樹 成原 健太郎 兼坂 茂 葛目 正央 佐々木 純 金子 有子
出版者
昭和大学学士会
雑誌
昭和医学会雑誌 (ISSN:00374342)
巻号頁・発行日
vol.60, no.5, pp.642-648, 2000-10-28 (Released:2010-09-09)
参考文献数
17

二酸化窒素吸入による中毒は防火作業, 溶接業, メッキ業などに従事する人に発症しやすいが, 本邦では余り知られていない.今回, 我々はメッキ業を営む64歳の男で硝酸と硫酸の混合液にニッケルメッキを賦したアルミ棒を挿入し, メッキ抽出作業中に二酸化窒素を吸入し, その後, 激しい呼吸困難と胸部圧迫感が出現, 近医にて急性肺水腫と診断され集中治療目的で本院救命センターに搬送後, 二酸化窒素による急性呼吸窮迫症候群 (acute respiratory distress syndrome・ARDS) と診断した症例を経験した.治療は人工呼吸管理を中心に最高気道内圧 (peak inspiratory pressure・PIP) , 肺胞の虚脱や無気肺の改善を目的として人工肺サーフアクタント, 更に各種ケミカルメデイエーター遊出阻止の目的でメチルプレドニゾロンの使用にて, 14日目には一般病棟に転出できた.本疾患は治療に比し予防が重要で, 作業所の改善や防護体制の整備, 更に疾患の存在を一般に認識させることが大切であると思われた.
著者
堤 信久 橋本 長人
出版者
公益社団法人 日本鋳造工学会
雑誌
鋳物 (ISSN:00214396)
巻号頁・発行日
vol.63, no.11, pp.877-882, 1991-11-25 (Released:2011-07-08)
参考文献数
10
被引用文献数
1

Two antagonistic properties i. e., higher modulus of elasticity and higher damping capacity are required simultaneously to piano frame with gray iron castings. With a view of improving the quality of present frame, damping capacity, natural frequency and power spectrum of gray cast iron specimen were analyzed by measuring the sound emission when the center of the specimen held at two fixed positions by tungsten wires was hammered on specially designed experimental apparatus. From results obtained, it has been clarified that the changing of matrix to ferritic from pearlitic raises damping capacity, but decreases power spectrum. The changing of matrix to pearlitic or martensitic from ferritic, however, lowers natural frequency which has been thought as the parameter of modulus of elasticity of cast iron.
著者
小森 憲治郎 谷向 知 数井 裕光 上野 修一
出版者
日本基礎心理学会
雑誌
基礎心理学研究 (ISSN:02877651)
巻号頁・発行日
vol.33, no.1, pp.55-63, 2014-09-30 (Released:2014-11-26)
参考文献数
39

Semantic dementia (SD) is a neurodegenerative disorder featured selective loss of semantic memory associated with a focal atrophy of the anterior temporal lobes. The aim of this study was to describe the clinical features of SD and to propose a coping method as a care for the patients with SD. Difficulties in naming and recognition of words with surface dyslexia on kanji-word reading [gogi-aphasia] are the most prominent symptoms in the patient with the left-dominant temporal lobe atrophy, while misidentification of familiar persons [prosopagnosia] and/or misunderstanding of visual objects [associative agnosia] is the characteristic of the patient with the right-dominant temporal lobe atrophy. Either symptom, however, rather appeared common in almost every SD patient from longitudinal perspectives of progressive amodal semantic impairment. Then the persistent stereotypies at an early stage of the disease turned into prominent and huge destructive behavior and psychological symptoms of dementia (BPSD). Quality associated way of care for patients with SD, early exposure to daily cognitive skill training utilizing preserved abilities and stepwise application to the care-services is essential.
著者
福井 次矢
出版者
一般社団法人 日本内科学会
雑誌
日本内科学会雑誌 (ISSN:00215384)
巻号頁・発行日
vol.87, no.10, pp.2122-2134, 1998-10-10 (Released:2008-06-12)
参考文献数
34
被引用文献数
4 5

1990年代に入って提唱された「信頼できる最新データに基づいた,理に適った医療」であるevidencebased medicine (EBM)は, (1)臨床上の疑問点抽出, (2)信頼性の高い結果(エビデンス)を示す文献の効率の検索, (3)臨床疫学と生物統計学の原理に則った,文献の批判的吟味, (4)得られたエビデンスの患者への適用性の判断,という4段階の手順から成る. EBMの主な活用場面は, (1)個々の患者での疑問点への対応,それに(2)頻度の高い臨床上の疑問点についての診療ガイドライン作成,である. EBMに則った診療を行うことで,入院患者については確固としたエビデンスに基づいた臨床判断を下す頻度が高くなった,診療ガイドラインを用いることで医師の診療行為だけでなく患者アウトカムも改善した,などのデータが報告され,医学教育にも大きく取り入れられつつある.世界的な規模でEBMが普及することにより,客観的な臨床データを重視した患者指向の医療が,今後ますます求められることになろう.
著者
Lei GONG Toshiyuki YAMAMOTO Takayuki MORIKAWA
出版者
Eastern Asia Society for Transportation Studies
雑誌
Asian Transport Studies (ISSN:21855560)
巻号頁・発行日
vol.4, no.1, pp.114-128, 2016 (Released:2016-03-01)
参考文献数
27

Ever since global positioning system (GPS) modules have been attached to smart phones, much research has focused on how to obtain personal trip (PT) information from them. One of the challenges is identifying activity type (or inferring the purpose of the trip) from these continuous GPS data. This paper focuses on obtaining the type of activity using several machine learning methods and comparing the results. The comparison is implemented from the perspective of accuracy and time cost in the phases of data training and prediction. After applying four machine learning methods to the data set obtained from 30 individuals in Nagoya, Japan, a classification tree method demonstrates superiority over support vector machine (SVM), neural network (NN), and discriminant analysis methods.
著者
Hyo Taek Lee Hyo Lyun Roh Yoon Sang Kim
出版者
理学療法科学学会
雑誌
Journal of Physical Therapy Science (ISSN:09155287)
巻号頁・発行日
vol.28, no.2, pp.626-631, 2016 (Released:2016-02-29)
参考文献数
16
被引用文献数
3

[Purpose] Currently, various simulators are produced and used for athlete’s exercise, rehabilitation, and training. In this study, we analyzed the kinematic factors of sectional and total movements in healthy participants by providing group-dependent information during simulated exercise. [Subjects and Methods] Participants in this study included 26 male adults (non-experts and experts); experts held a certificate issued by the Korea Ski Instructors Association. The elapsed times in each phase, the difference in the lower extremity angles, and muscle activity were computed through analysis of kinematic factors. [Results] We observed that motions in the experts took shorter time to perform than that in non-experts, and showed larger variation of lower limb joint angle in most events during simulated skiing. There were also significant group-dependent differences in the peak and mean EMG values during simulated skiing. [Conclusion] A non-expert’s posture leads to enhanced muscle activity to keep the lower body in balance. We suggest the following training guideline: initially, non-experts should maintain appropriate range of motion with lower-intensity exercise to improve muscle endurance. It can be useful in providing preliminary data for future training and rehabilitation studies, as well as improvements in muscle strength and balance.
著者
坂下 美彦 藤川 文子 秋月 晶子 藤里 正視
出版者
日本緩和医療学会
雑誌
Palliative Care Research (ISSN:18805302)
巻号頁・発行日
vol.11, no.1, pp.316-320, 2016 (Released:2016-03-04)
参考文献数
12

【緒言】SEIQoL-DWは半構造化面接により患者が大切に思う5つの領域に焦点をあてて個人のQOLを測定する方法である.本研究は進行がん患者の大切に思う領域と主観的QOLの変化について病状悪化の経過の中で縦断的に評価するのを目的とした.【方法】痛みがSTAS1以下などを適格基準としSEIQoL-DW を1年間に緩和ケア外来(1回目)と入院後(2回目)に実施した症例を対象とした.【結果】対象は5例(男1,女4,年齢67.6歳)であった.1回目面接時P.S.は全例1に対し,2回目面接時には3ないし4であった.面接の間隔は平均164日.全例において大切な領域の内容は5つのうち3つ以上が変化した.全般的主観的QOLを意味するSEIQoL-indexは3例で上昇し2例で低下した.【結論】終末期に患者が大切に思う領域は大きく変化する.個人の主観的QOLは全身状態の低下とは必ずしも一致しない.
著者
Yuki Nanke Tsuyoshi Kobasigawa Keiko Yoda Hisashi Yamanaka Shigeru Kotake
出版者
一般社団法人 日本内科学会
雑誌
Internal Medicine (ISSN:09182918)
巻号頁・発行日
vol.55, no.5, pp.515-517, 2016 (Released:2016-03-01)
参考文献数
16

Behçet's disease (BD) is a polysymptomatic and recurrent systemic vasculitis with a chronic course and unknown cause. We herein report a 27-year-old woman who had suffered from a recurrent fever and tonsillitis for nearly ten years with BD for who tonsillectomy was effective.
著者
Satoshi MAESAWA Epifanio BAGARINAO Masazumi FUJII Miyako FUTAMURA Toshihiko WAKABAYASHI
出版者
社団法人 日本脳神経外科学会
雑誌
Neurologia medico-chirurgica (ISSN:04708105)
巻号頁・発行日
pp.ra.2015-0302, (Released:2016-02-29)
参考文献数
81
被引用文献数
9

Cutting-edge neuroimaging technologies can facilitate preoperative evaluation in various neurosurgical settings. Surgery for gliomas and epilepsy requires precise localization for resection due to the need to preserve (or perhaps improve) higher cognitive functions. Accordingly, a hodological approach should be taken that considers subcortical networks as well as cortical functions within various functional domains. Resting state functional magnetic resonance imaging (fMRI) has the potential to provide new insights that are valuable for this approach. In this review, we describe recent developments in network analysis using resting state fMRI related to factors in glioma and epilepsy surgery: the identification of functionally dominant areas, evaluation of cognitive function by alteration of resting state networks (RSNs), glioma grading, and epileptic focus detection. One particular challenge that is close to realization is using fMRI for the identification of sensorimotor- and language-dominant areas during a task-free resting state. Various RSNs representative of the default mode network demonstrated at least some alterations in both patient groups, which correlated with behavioral changes including cognition, memory, and attention, and the development of psychosis. Still challenging is the detection of epileptic foci and propagation pathways when using only network analysis with resting state fMRI; however, a combined method with simultaneous electroencephalography has produced promising results. Consequently, network analysis is expected to continue to advance as neuroimaging technology improves in the next decade, and preoperative evaluation for neurosurgical parameters through these techniques should improve parallel with them.
著者
Naokata Ishii Riki Ogasawara Koji Kobayashi Koichi Nakazato
出版者
一般社団法人日本体力医学会
雑誌
The Journal of Physical Fitness and Sports Medicine (ISSN:21868131)
巻号頁・発行日
vol.1, no.1, pp.83-94, 2012-05-25 (Released:2012-08-22)
参考文献数
118
被引用文献数
2 11 6

To learn the mechanisms underlying resistance exercise-induced muscle hypertrophy, recent studies on muscle protein metabolism and myogenic progenitor cells were reviewed. Numerous studies have suggested that activation of the translation process plays a major role in a resistance exercise-induced increase in muscle protein synthesis, and also in muscle hypertrophy after a prolonged period of training. Among regulators of the translational activity, the mTORC1 signaling pathway has been shown to be important, although the relation between its upstream regulation and exercise regimen remains unclear. In addition, the muscle satellite cells play a part, even if not indispensable, in exercise-induced muscle hypertrophy, by supplying muscle fibers with new myonuclei. Middle to high exercise intensity has been regarded as essential for gaining muscle mass, because it causes the recruitment of large motor units with fast, type II muscle fibers, which are readily hypertrophied through activation of mTORC1 signaling. However, several studies have shown that low-intensity resistance exercises with either large exercise volume or prolonged contraction time effectively activate protein synthesis and induce muscle hypertrophy. These findings suggest that various strategies are possible in exercise regimens, and exercise intensity is not necessarily a primary factor for gaining muscular size.
著者
佐藤 朋覚 熊谷 昌則 天野 敏男 小川 信明
出版者
公益社団法人 日本分析化学会
雑誌
分析化学 (ISSN:05251931)
巻号頁・発行日
vol.52, no.9, pp.653-660, 2003 (Released:2004-01-30)
参考文献数
24
被引用文献数
1 6 2

携帯可搬型の近赤外分光分析装置を用いて,清酒(日本酒)のスペクトルを測定し,ケモメトリックスを用いて判別分析を行い,その分類に対して化学的な解釈を加えた.近赤外スペクトルでの主成分分析で得られた波長寄与率スペクトルから,第1主成分(PC1)はアルコールの -CH3,-CH2-,R-OHの寄与が高く,第2主成分(PC2)はタンパク質の -NH2,-CONH2,-CONH-,-CH3,-CH2- の寄与が高く,第3主成分(PC3)はデンプンの -CH3,-CH2-,-OHの寄与が高いことが推定できた.近赤外スペクトルでの違いが,PC1では純米酒とそれ以外に,PC2では大吟醸酒とそれ以外に,PC3では純米大吟醸酒・本醸造酒,普通酒・大吟醸酒,純米酒にそれぞれ分類できることが分かった.携帯可搬で現場測定が可能なPlaScan-SHは清酒の判別に有用である.
著者
辻内 順平
出版者
公益社団法人 応用物理学会
雑誌
応用物理 (ISSN:03698009)
巻号頁・発行日
vol.69, no.8, pp.923-928, 2000-08-10 (Released:2009-02-05)
参考文献数
28

20世紀における応用光学の歴史を展望した. 20世紀前半は,目の機能を補い,拡張するための可視域の光学機械が主な対象であった. 20世紀の半ばを過ぎて,レーザーの発明,エレクトロニクス・コンピユーターの発展があり,それに支えられて,光エレクトロニクス,コンピューター支援光学技術,さらに光エンジニアリングが発展して,応用光学の近代化が起こり,他の分野の基礎技術となる新しい用途も開拓され.今後の応用光学の方向が定まった.