著者

近藤 英一

出版者

公益社団法人 精密工学会

雑誌

精密工学会誌 (ISSN:09120289)

巻号頁・発行日

vol.86, no.9, pp.671-674, 2020-09-05 (Released:2020-09-05)

被引用文献数

1 1

著者

田中 篤 高橋 宏樹 根津 佐江子 上野 義之 菊池 健太郎 渋谷 明隆 大平 弘正 銭谷 幹男 Lorenzo Montali Pietro Invernizzi 滝川 一

出版者

一般社団法人 日本肝臓学会

雑誌

肝臓 (ISSN:04514203)

巻号頁・発行日

vol.50, no.2, pp.51-59, 2009 (Released:2009-03-02)

参考文献数

32

被引用文献数

1 1

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疲労は原発性胆汁性肝硬変(PBC)患者の主要症状の一つとされており,近年欧米では臨床上の重要な問題としてPBC患者の疲労に関する報告が相次いでいるが,日本人PBC患者における疲労症状の実態は不明である.われわれは疲労症状の評価尺度として頻用されるFisk Fatigue Severity Score(FFSS)の日本語版をback translation法によって作成し,日本人PBC患者166名を対象としてその妥当性を統計学的に検証した.クロンバックのα係数は0.900を超えており,評価尺度の内的整合性は良好であった.SF-36との間にも高い相関が存在し,ことに疲労と関係の深い「活力」「日常役割機能(身体)」との間に最も強い相関がみられた.主因子法による探索的因子分析ではphysical, cognitive, socio-relational, socio-emotionalと推定される4因子が抽出され,これらによって結果全体の66%が説明可能であった.以上より今回作成した日本語版FFSSの妥当性が検証された.今後これを用いて日本人PBC患者の疲労症状について詳細に検討する予定である.

著者

仲 弥

出版者

日本医真菌学会

雑誌

Medical Mycology Journal (ISSN:21856486)

巻号頁・発行日

vol.53, no.3, pp.163-167, 2012 (Released:2012-08-23)

参考文献数

25

被引用文献数

1 1

著者

佐藤 健生

出版者

現代史研究会

雑誌

現代史研究 (ISSN:03868869)

巻号頁・発行日

vol.40, pp.12-19, 1994-12-17 (Released:2020-11-26)

参考文献数

4

著者

Reiko Okada Masayuki Teramoto Isao Muraki Akiko Tamakoshi Hiroyasu Iso

出版者

Japan Epidemiological Association

雑誌

Journal of Epidemiology (ISSN:09175040)

巻号頁・発行日

pp.JE20220118, (Released:2022-09-24)

参考文献数

34

被引用文献数

2

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BackgroundLittle is known about the impacts of sleep duration and daytime napping on the risk of type 2 diabetes mellitus (T2DM).MethodsIn this study, 20,318 participants (7,597 men, 12,721 women) aged 40–79 years without a history of T2DM, stroke, coronary heart disease, or cancer at baseline (1988–1990), completed the baseline survey and the 5-year follow-up questionnaires, which included average sleep duration, napping habits, and self-reports of physician-diagnosed diabetes. The multivariable odds ratios (ORs) with 95% confidence intervals (CIs) were calculated using a logistic regression model.ResultsDuring the 5-year follow-up, 531 new cases of T2DM (266 men and 265 women) were documented. Sleep duration ≥ 10 h was associated with higher risk of T2DM compared to sleep duration of 7 h (OR 1.99: 95%CI, 1.28–3.08). The excess risk was observed for both sexes and primarily found among the non-overweight; the multivariable ORs of sleeping ≥ 10 h compared to 7 h were 2.05 (1.26–3.35) for the non-overweight (BMI < 25 kg/m2) and 1.38 (0.49–3.83) for the overweight (BMI ≥ 25 kg/m2). The respective ORs of nappers vs non-nappers were 1.30 (1.03–1.63) and 0.92 (0.65–1.29). Among the non-overweight, nappers who slept ≥ 10 h had the highest risk of T2DM (OR 2.84: 95%CI, 1.57–5.14), non-nappers who slept ≥ 10 h (2.27: 1.27–4.06), and nappers who slept < 10 h (1.30: 1.03–1.64), compared with non-nappers who slept < 10 h.ConclusionsLong sleep duration was associated with the risk of T2DM in both sexes, which was confined to the non-overweight.

著者

土金 真人 壷井 伯彦 西村 奈穂 窪田 満 宇田川 恵里子 中舘 尚也 中川 聡

出版者

一般社団法人 日本集中治療医学会

雑誌

日本集中治療医学会雑誌 (ISSN:13407988)

巻号頁・発行日

vol.28, no.6, pp.547-548, 2021-11-01 (Released:2021-11-01)

参考文献数

7

著者

粟津原 宏子

出版者

一般社団法人 日本調理科学会

雑誌

調理科学 (ISSN:09105360)

巻号頁・発行日

vol.15, no.2, pp.114-118, 1982-06-20 (Released:2013-04-26)

参考文献数

7

被引用文献数

2

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卵の熱凝固性に関する基礎的研究として,卵白,卵黄,全卵の各希釈液に食塩(0,0.5,1.0,1.5,2.0,2.5%),砂糖(0,10,20,30%)を添加した場合の凝固力の変化および食塩添加による凝固温度の変化を調べた.1.食塩は卵白,卵黄の凝固に対して全く異なった影響を与えた.卵白では0.5%でも無添加に比べて凝固力は著しく促進され,1.0%で最高となるが,添加量による差は小さかった.卵黄では1.0%添加まではあまり影響がなく,1.5~2.0%で著しく凝固が促進された.全卵は食塩添加量の増加に従い凝固力を増したが,その変化は卵白,卵黄における変化をほぼ反映しているようであった.2.砂糖添加の影響は卵白で最も大きくゼリー強度が著しく減少した.卵黄も砂糖添加によリゼリー強度がかなり減少したが,全卵では減少の程度が小さかった.硬さは卵白,卵黄,全卵共同じように低下し,卵白ではゼリー強度の減少の割に硬さの低下が小さかった.3.凝固温度は卵白,卵黄,全卵共食塩量の増加と共に上昇し,特に卵白に食塩1.5%以上添加した場合には著しく上昇した.

著者

日浅 崇馬 佐藤 隆紀 風間 英気 明 愛国 下条 誠

出版者

一般社団法人 日本機械学会

雑誌

ロボティクス・メカトロニクス講演会講演概要集 2017 (ISSN:24243124)

巻号頁・発行日

pp.2P1-K06, 2017 (Released:2017-11-25)

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Within limbs of typical animals, there are bi-articular muscle-tendon complex crossing two joints. In particular, it is known that the bi-articular muscle-tendon complex between hip joint and knee joint contributes to the dynamic motion such as high jumping and fast running. This realizes transfer of the torque between the two joints and storage and reuse of the elastic energy. In this paper, we introduce the muscle-tendon complex between hip joint and knee joint to the hind legs of the quadruped robot. In the vertical jump simulation, we confirmed that the mechanism enabled the leg to transfer the torque between the two joints and the leg with the mechanism realized higher jump than the one without it. A prototype of the mechanism has been fabricated also.

著者

内山 巌雄

出版者

一般社団法人日本リスク研究学会

雑誌

日本リスク研究学会誌 (ISSN:09155465)

巻号頁・発行日

vol.21, no.3, pp.175-182, 2011 (Released:2012-03-27)

参考文献数

18

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For complete revival of the East Japan great earthquake, withdrawal of waste and sludge, disassemble of collapse buildings, etc. are performed over a long period of time. In these cases, many particulate matters included asbestos are generated, and will induce lung cancer or mesothelioma in tens of years. Since the health risk following exposure to the present environmental concentration of asbestos is about 10-5, we should control the scattering of asbestos into environment and prevent the inhalation by wearing an anti-dust mask (national assay disposable mask DS2, N95) .

著者

Seiichi Mokuyasu Risa Oshitanai Toru Morioka Yuki Saito Yasuhiro Suzuki

出版者

Japanese Society of Laboratory Medicine

雑誌

Laboratory Medicine International (ISSN:24368660)

巻号頁・発行日

vol.2, no.3, pp.50-59, 2023 (Released:2023-12-29)

参考文献数

30

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Background: Absolute lymphocyte count (ALC) and neutrophil lymphocyte rate (NLR) as immune system and inflammatory markers have been suggested as prognostic factors in eribulin treatment. However, the respective cut-off values have not been determined. Hence, we investigated the relationship between overall survival (OS) and baseline ALC (bALC) and baseline NLR (bNLR) in eribulin-treated patients with human epidermal growth factor receptor 2 (HER2)-negative breast cancer (BC) by using 2 types of cut-off values for each. Methods: Univariate and multivariate analyses were performed to investigate the association of bALC and bNLR with OS among 114 female patients with HER2-negative BC treated with eribulin. Results: The OS of patients with HER2-negative BC was compared based on bALC (cut-off value: 1,200/μL and 1,500/μL) and bNLR (cut-off values: 2 and 3). A significant difference was observed in median OS between patients with bALC of ≥ 1,200/μL and those with bALC of < 1,200/μL (hazard ratio [HR]: 0.596 [0.395, 0.889], p = 0.014). For bNLR (cut-off value: 2), the median OS was significantly higher in patients with a bNLR of < 2 than in those with a bNLR of ≥ 2 (HR: 0.629 [0.406, 0.974], p = 0.038). Conclusions: Patients with HER2-negative BC with a bALC of ≥ 1,200/μL showed a longer OS than patients with a bALC of < 1,200/μL, thus suggesting that survival prediction using bALC was effective for eribulin-treated patients with recurrent HER2-negative BC. It should be noted that the optimal cut-off value for ALC may change depending on the target patient group.

著者

Shingo Tanaka Noboru Ohba Kiyoshi Abe Yuka Tamoto Kenji Yasui Chihiro Kobayashi Nagomi Saito Koji Miyanishi Satoshi Takahashi Junji Kato

出版者

Japanese Society of Laboratory Medicine

雑誌

Laboratory Medicine International (ISSN:24368660)

巻号頁・発行日

vol.2, no.3, pp.42-49, 2023 (Released:2023-12-29)

参考文献数

24

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Aims: Attenuation imaging (ATI) is a new ultrasonography method of evaluating hepatic steatosis. Attenuation coefficients (ACs) in the region of interest are measured using two-dimensional ultrasonography. ATI also displays the coefficient of determination (R2) as an index of AC reliability. This study aimed to elucidate R2 values in patients who underwent ATI in clinical practice and to determine factors that influence R2 values. Methods: This study included 749 patients who underwent ATI to evaluate hepatic steatosis at a single center. All abdominal ultrasound examinations were performed by one of the five experienced ultrasonographers. The AC and R2 values were measured five times, and the median values were calculated. Multivariate analysis was conducted to identify factors affecting R2 values. Results: One hundred and nine (15%) patients showed R2 values of < 0.80, of which 108 had non-fatty liver. Further, the R2 value was strongly correlated with AC (correlation coefficient = 0.842). Uncomplicated diabetes (Odds ratio [OR], 2.68) and AC (< 0.60 dB/cm/MHz; OR, 72.76) were identified as independent factors associated with low R2 values (< 0.80). Conclusion: ATI in patients with non-fatty liver showed low R2 values. Worldwide standardization of the ATI measurement method is urgently needed for consistent results.

著者

Jeong Hui Kim Ryosuke Kikuchi Atsuo Suzuki Rika Watarai Kaori Goto Yui Okumura Tadashi Matsushita

出版者

Japanese Society of Laboratory Medicine

雑誌

Laboratory Medicine International (ISSN:24368660)

巻号頁・発行日

vol.2, no.3, pp.60-66, 2023 (Released:2023-12-29)

参考文献数

24

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The immune system produces antibodies following SARS-CoV-2 infection and vaccination. However, we lack comprehensive information about the humoral responses after infection and vaccination, which are similar but might differ in type or amount of produced antibodies. Therefore, we compared different types and amounts of antibodies produced by the immune system in response to infection versus those produced by BNT162b2 (Pfizer/BioNTech) vaccines. Our findings indicated that naturally infected individuals had 14-fold higher anti-SARS-CoV-2 spike protein (anti-S) and 41-fold higher anti-SARS-CoV-2 receptor-binding domain of the viral spike protein (anti-RBD) IgM titers than SARS-CoV-2-naïve vaccinees. Remarkably, naturally infected individuals maintained high levels of IgM antibody titers up to six weeks after symptom onset. A significantly rapid increase in anti-S IgG titers in primary infection was observed, eventually reaching a level similar to that in people who had third booster vaccination. This study revealed the characteristics of the target antigen and immunoglobulin isotypes after natural SARS-CoV-2 infection and COVID-19 vaccination.

著者

Fangyu Yan Ehab S. Eshak Ahmed Arafa Akiko Tamakoshi Hiroyasu Iso the JACC Study Group

出版者

Japan Epidemiological Association

雑誌

Journal of Epidemiology (ISSN:09175040)

巻号頁・発行日

pp.JE20220063, (Released:2022-07-23)

参考文献数

54

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Background: Limited reports from human prospective studies investigated the possible role of vitamin K in the development of lung cancer although vitamin K’s anticarcinogenic activities were verified from several in vitro and in vivo studies.Objectives: We investigated the associations between total vitamin K intake from food and the development of lung cancer based on this large prospective cohort study.Methods: A validated food frequency questionnaire was used to examine vitamin K intake among 42,166 (16,341 men and 25,825 women) at the Japan Collaborative Cohort Study's baseline (1988-1990). Hazard ratios (HRs) and 95% confidence intervals (CIs) of incident lung cancer were calculated using the Cox proportional hazard regression method based on vitamin K consumption quartiles.Results: 430 cases (308 males and 122 women) of lung cancer were documented during a total of 564,127 person-years of follow-up (median follow-up= 14.6 years). Vitamin K consumption was shown to be inversely related to lung cancer risk; the multivariable HR (95 % CI) for the highest vs. lowest quartiles was 0.67 (0.46-0.96; p for trend = 0.010). This relationship appears to be stronger in males [0.62 (0.40-0.96); p for trend=0.016] than in females [0.82 (0.42-1.61); p for trend=0.39] (p for interaction=0.012), and in ever smokers [0.57 (0.36-0.91); p for trend=0.006] than in never smokers [0.79 (0.40-1.55); p for trend=0.37] (p for interaction= 0.30). The individuals' age, BMI, or alcohol consumption status had no effect on the observed connection.Conclusion: Vitamin K consumption reduces the risk of lung cancer. More research is needed to clarify the molecular processes behind this connection.

著者

秋山 央 伊藤 健士

出版者

日本バレーボール学会

雑誌

バレーボール研究 (ISSN:13449524)

巻号頁・発行日

vol.23, no.1, pp.39-48, 2021 (Released:2021-08-13)

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With the objective of clarifying which performance indices are correlated with the outcome of the game for attacks following serve-reception in international men's volleyball tournaments, this study analyzed the 2015 Volleyball Men's World Cup. The results obtained are as follows. (1) Considering all attacks when in-system, and using each team's percentage of winning the set as the variable, very strong positive correlations were confirmed for the attack efficiency (r =0.948, p <.001) and kill attack percentage (r =0.902, p <.001). (2) Considering quick attacks when in-system, and using each team's percentage of winning the set as the variable, a very strong positive correlation was confirmed for the attack efficiency (r =0.787, p <.01) and kill attack percentage (r =0.711, p <.01), and a relatively strong negative correlation was confirmed for the percentage of losing points from an attack (r =-0.582, p <.05). (3) Considering pipe attacks when in-system, and using each team's percentage of winning the set as the variable, very strong positive correlations were confirmed for the kill attack percentage (r =0.876, p <.001) and attack efficiency (r =0.784, p <.01), and a relatively strong positive correlation was confirmed for the attack attempt percentage (r =0.629, p <.05). (4) Considering front side attacks when out-of-system, and using each team's percentage of winning the set as the variable, a relatively strong negative correlation was confirmed for the blocked attack percentage (r =-0.606, p <.05).From the above, it became clear that in terms of attacks following serve-reception at the 2015 Volleyball Men's World Cup, in-system attacks are correlated with the outcome of the game, especially with correlations found in the potency and accuracy of quick attacks, and the potency and frequency of pipe attacks. In addition, it was confirmed that for out-of-system front side attacks, the points lost due to being blocked by the opponent had a correlation with the outcome of the game.

著者

大山 惣寿郎 佐藤 豊 平間 光雄 塔尾 武夫

出版者

一般社団法人 日本体育・スポーツ・健康学会

雑誌

体育学研究 (ISSN:04846710)

巻号頁・発行日

vol.12, no.5, pp.280, 1968-07-05 (Released:2016-12-31)

著者

福留 邦洋

出版者

一般社団法人 地域安全学会

雑誌

地域安全学会論文集 (ISSN:13452088)

巻号頁・発行日

vol.10, pp.503-509, 2008-11-14 (Released:2019-04-18)

参考文献数

11

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In this paper, the following were examined : Positioning of the contribution in the regional disaster prevention plan, tendency of the contribution in earthquake hazard after Hanshin Awaji Earthquake disaster, content of contribution allocation in recent large earthquake disaster. The allocation considering the regionality was able to be confirmed. It is considered that the contribution is a part of the victim supporting measures.

著者

藤井 正純 二村 美也子 蛭田 亮

出版者

一般社団法人 日本高次脳機能学会

雑誌

高次脳機能研究 (旧 失語症研究) (ISSN:13484818)

巻号頁・発行日

vol.42, no.3, pp.321-325, 2022-09-30 (Released:2022-11-24)

参考文献数

8

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覚醒下手術は, 脳内に染み込むようにして発育するグリオーマと呼ばれる脳腫瘍や, 薬でどうしても抑えられないような発作で困っているてんかんの症例に行われ, 成果をあげています。日本では世界に先駆けて覚醒下手術のガイドラインが策定され, 一定の条件を満たした施設を認定する制度が発足し, 健康保険の仕組みのなかに組み込まれるまでになり, 現在普及が進んでいます。覚醒下手術は, 脳機能のなかでも特に, 言語を含む高次脳機能を守る手術です。患者一人ひとりの社会背景や人生を考えて, 機能の温存と病変の切除の両立を目指して頑張る取り組みである一方, ここで得られる所見は, 高次脳機能に関するかけがえのない本物の情報でもあります。また, 脳神経外科医だけでなく, 評価者として脳神経内科医・言語聴覚士・作業療法士など多職種の連携が欠かせません。本稿は, そんな多職種の方々が, このやりがいのある手術に興味をもつきっかけになれば幸いです。

著者

田村 理納 宮澤 理稔

出版者

公益社団法人 日本地震学会

雑誌

地震 第2輯 (ISSN:00371114)

巻号頁・発行日

vol.69, pp.99-111, 2017-03-10 (Released:2017-05-16)

参考文献数

45

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We investigated the triggering process for the Mj6.4 Eastern Shizuoka earthquake of 15 March 2011, which occurred 4 days after the 2011 Mw9.0 Tohoku-Oki earthquake and about 4 minutes after the Mj6.2 Fukushima-Oki earthquake. The static Coulomb failure stress change on the fault of the Eastern Shizuoka earthquake from the Tohoku-Oki earthquake, was about 20 kPa, and the largest dynamic stress change by the passing surface waves was about 200 kPa. The largest dynamic stress change from the Fukushima-Oki earthquake and the largest tidal stress change after the Tohoku-Oki and before the Eastern Shizuoka earthquake were about 0.3 kPa and 1.4 kPa, respectively, while those at the onset of the Eastern Shizuoka earthquake were at most 0.01 kPa and −0.5 kPa, respectively. We also analyzed seismicity by detecting earthquakes immediately preceding the Eastern Shizuoka earthquake, which is done using a matched filter technique. A single M1.0 event that occurred about 17 hours before the Eastern Shizuoka earthquake and located about 3 km NNE from the hypocenter was found, however, this event may not be classified as a foreshock if we consider the background seismicity in this region before 2011. We propose that the seismic cycle was possibly advanced by about 101 to 102 years and delayed triggering might have occurred for the Eastern Shizuoka earthquake. The eventual earthquake was ready to occur to some extent, when the Tohoku-Oki earthquake occurred. The fault strength had significantly decreased due to imposed large dynamic and static stress changes from the Tohoku-Oki earthquake and probably its large aftershocks, in terms of a rate and state dependent friction law.

著者

吉成 直樹 永瀬 克己 藤井 貞和 橋尾 直和 谷本 晃久 島村 幸一 安江 孝司 本田 優子 佐々木 利和

出版者

法政大学

雑誌

基盤研究(B)

巻号頁・発行日

2004

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本研究は、「日本」の両端に配置されているアイヌと沖縄のふたつの社会が、いかにヤマト社会と対峙しながら、そのアイデンティティを形成、維持してきたかという点に最終的な目的がある。ある社会のアイデンティティの核心にあるのは、言語および言語表現である。その素材として、アイヌ口承文学、琉球(首里)王府が16世紀〜17世紀に編纂した古歌謡集『おもろさうし』を主に扱った。特に、それらのテキストから、文字の無かった時代の「歴史」の復元を行う作業に労力を注いだ。たとえば、アイヌ口承文学から復元される「歴史」とは何か、『おもろさうし』から復元できる「歴史」とは何か、という問いである。「歴史」の復元の方法として、言語表現ばかりではなく、絵画や図像から「歴史」の復元を試みた。絵画、図像は、どのような社会や文化(精神世界を含めて)であったかを知るうえで重要な手がかりになるばかりではなく、文字の無かった社会の歴史復元においてはきわめて有効である。また、民俗、言語の立場から、アイヌ、沖縄の双方の社会を視野に入れた成果を得た。これは、現在のアイヌと沖縄の文化、言語を比較しようとするものでなく、それぞれの文化のさらに基層にある民俗、言語を明らかにしようとするものである。本研究を展開していく過程で、琉球社会・文化の形成に関する、大きな研究の転換期を迎えた。奄美諸島社会の古代〜中世並行期にかけての考古学的状況が明らかになるにつれ、琉球社会が従来、考えられていたような内的な発展のみで形成したとは考えられなくなったことである。この問題は、言語にかかわる分野のみならず、さまざまな分野の見直しを迫る可能性があり、また本研究の課題にも深くかかわっていたため、最終年度には、その調査・研究も手がけた。