著者

安藤 繁 篠田 裕之 小川 勝也 光山 訓

出版者

公益社団法人 計測自動制御学会

雑誌

計測自動制御学会論文集 (ISSN:04534654)

巻号頁・発行日

vol.29, no.5, pp.520-528, 1993-05-31 (Released:2009-03-27)

参考文献数

13

被引用文献数

5 21

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This paper describes a theory, algorithm, and experimental results of a new 3-D sound source localization system which is based on the spatio-temporal derivative method applied to acoustic signals.The principle is outlined as follows. We observe the sound field through amplitude f and its spatiotemporal gradients fx, fy, ft of a single point. An instantaneous distribution of time-varying vectors fx, fy, ft, f in a 4-D gradient space is classified according to its degree of orderness. Each orderness is theoretically related to constraints on possible source locations. Under this classification, we obtain an unambiguous 3-D location of a single source under a second degree of orderness and a co-existing line or plane of double sources under a first degree of orderness.We applied the principle to a sound source visualizer system by which a possibility map of the source locale is accumulated and superposed realtimely on TV images. By several experiments, this system is shown to be able to localize multiple wideband sources such as white noises and human voices while discriminating a number of them.

著者

萩谷 俊一

出版者

関東東山病害虫研究会

雑誌

関東東山病害虫研究会年報 (ISSN:03888258)

巻号頁・発行日

vol.1970, no.17, pp.104-104, 1970-10-31 (Released:2010-03-12)

著者

志賀 正年

出版者

日本中国語学会

雑誌

中国語学 (ISSN:05780969)

巻号頁・発行日

vol.1957, no.60, pp.57-62, 1957-03-15 (Released:2010-06-11)

被引用文献数

1

著者

山口 明彦 藤本 徳毅 寺村 和也 加藤 威 古田 未征 田中 俊宏

出版者

日本皮膚科学会大阪地方会・日本皮膚科学会京滋地方会

雑誌

皮膚の科学 (ISSN:13471813)

巻号頁・発行日

vol.15, no.2, pp.57-62, 2016 (Released:2016-06-02)

参考文献数

15

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30歳代,男性。2009年3月上旬より特に誘因なく両下腿に紅斑が出現し,徐々に上肢にも拡大し発熱を伴うようになったため前医を受診した。セファゾリンの投与を受けたが軽快せず,D-dimmer 上昇,血小板低下を認め,原因不明の播種性血管内凝固と診断された。メシル酸ナファモスタットを投与され凝固異常は改善したが,発熱が持続しイミペネムの投与を開始されたが無効であった。このためステロイド内服やステロイドパルス療法も行われたが,発熱が持続するため当院転院となった。受診時,患者は Yamaguchi らの基準のリンパ節腫大以外のすべての項目を満たし,検査結果と合わせて感染症,悪性腫瘍,膠原病を除外し,成人発症 Still 病と診断した。ステロイドの単独治療,ステロイドパルス療法,メトトレキサート,シクロスポリンの併用,二重濾過血漿交換,コルヒチン内服のいずれにも著明な反応を示さず,軽快と増悪を繰り返した。治療抵抗性の成人発症 Still 病であり,IL-6 の高値を認めたため Tocilizumab の適応と判断し,Tocilizumab とステロイド内服の併用療法を開始したが病勢は完全には治まらず,最終的に Tocilizumab とメトトレキサート,ステロイド内服の併用により長期の寛解を得ることができた。Tocilizumab の難治性成人発症 Still 病に対する有効性については,今後も本例のような症例の積み重ねが必要と思われる。(皮膚の科学,15: 57-62, 2016)

著者

山口 雅也 大田 明英

出版者

一般社団法人 日本内科学会

雑誌

日本内科学会雑誌 (ISSN:00215384)

巻号頁・発行日

vol.80, no.11, pp.1771-1774, 1991-11-10 (Released:2008-06-12)

参考文献数

5

被引用文献数

2 2

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成人Still病は,関節疾患としてよりも熱性疾患としてその存在が注目されている.今回はその診断および鑑別診断に重点をおいて解説した.分類基準は,大項目として, (1)発熱, (2)皮疹, (3)関節痛, (4)白血球増加,小項目として(5)咽頭痛, (6)肝機能異常, (7)RFとANA陰性, (8)肝脾腫またはリンパ節腫脹,の計8項よりなり,これらのうち5項目(大項目2以上を含む)以上を満たす症例を成人Stil1病と分類する.

著者

山口 雅也

出版者

一般社団法人 日本内科学会

雑誌

日本内科学会雑誌 (ISSN:00215384)

巻号頁・発行日

vol.82, no.9, pp.1577-1582, 1993-09-10 (Released:2008-06-12)

参考文献数

7

出版者

The Anthropological Society of Nippon

雑誌

東京人類學會雜誌 (ISSN:18847641)

巻号頁・発行日

vol.4, no.35, pp.188b-188b, 1889 (Released:2011-07-01)

著者

青木 正和 片山 透 山岸 文雄 横田 総一郎 亀田 和彦 斎藤 肇 原 耕平 江崎 孝行 河合 忠 四元 秀毅 関口 進

出版者

一般社団法人 日本結核病学会

雑誌

結核 (ISSN:00229776)

巻号頁・発行日

vol.69, no.10, pp.593-605, 1994-10-15 (Released:2011-05-24)

参考文献数

8

被引用文献数

8

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Recently, a new kit to detect and indentify mycobacteria in clinical specimens was developed by Japan Roche Co. Limited. The new method is based on amplification of DNA of mycobacteria in clinical specimens by PCR and hybridization of amplified DNA b. microwell plate hybridization method, which is the “AmplicorTM Mycobacteria, Roche. (AMP-M) ”. Cooperative study was organized with 15 tuberculosis hospitals and institu tions throughout Japan, and 349 clinical specimens from newly admitted tuberculosis patients and/or suspects were collected during July and August, 1993. All the specimens were examined by smear microscopy (Ziehl-Neelsen's staining), culture on Ogawa egg media, culture on variant 7H9 liquid media and by AMP-M. Excluding 25 specimens which had failed to identify the species of mycobacteria because of contamination, disability to multiply on the transplanted solid media and so on, the results of the examinations in 324 specimens consisting of 167 specimens from previously untreated cases and those of 157 specimens from previously treated cases were analysed. Main results obtained were as follows;1. Of 70 smear positive specimens from previously untreated cases, culture positive on Ogawa media and 7H9 media, and by AMP-M positive were 59 (84.3%), 61 (87.1%) and 66 (94.3%), respectively. Of 97 smear negative specimens, culture positive were 20 (20.6%), 22 (22.7%) and 27 (27.8%), respectively. The AMP-M showed the highest positive rate in both groups.2. The sensitivity and the specificity of AMP-M in previously untreated cases were calculated by assuming that positive on Ogawa and/or variant 7H9 media is “positive”. The sensitivity was 95.8% (68/71) and the specificity was 94.8% (91/96) for M. tuberculosis in previously untreated cases. The sensitivity and the specificity for M. avium and M. intracellulare were all 100%, although the numbers observed were small.3. So-called false positive of the AMP-M were observed in 5 cases out of 96 culture negatives on both Ogawa and variant 7H9 media. However, all 5 cases were positive by repeated AMP-M, 3 become culture positive later, and another 2 showed clinical findings consistent with tuberculosis. Hence, the authors considered that the false positive rate of the AMP-M method is to be very low in previously untreated cases.4. Of 86 smear positive cases with history of previous chemotherapy, the positive culture on Ogawa media, variant 7H9 media and that by AMP-M method were 64 (74.4%), 77 (89.5%) and 85 (98.8%), respectively. In the smear negative cases, culture positive was 10 out of 71 (14.1%), 13 (18.3%) and 24 (33.8%), respectively.5. The sensitivity and the specificity of the AMP-M were 98.7% (77/78) and 81.0% (64/79) for M. tuberculosis in previously treated cases calculated by the same method as in previously untreated cases. They were 77.8% (7/9) and 100% (148/148) for M. avium, and 100% (4/4) and 100% (153/153) for M. intracellulare.Based on these results, the authors concluded that the AMP-M is a very efficient and rapid method to detect and identify M. tuberculosis, M. avium and/or M. intracellulare in clinical specimens. This method will be useful to diagnose tuberculosis and diseases caused by mycobacteria other than M. tuberculosis rapidly.

著者

芳司 俊郎 杉本 旭

出版者

独立行政法人 労働安全衛生総合研究所

雑誌

労働安全衛生研究 (ISSN:18826822)

巻号頁・発行日

vol.6, no.2, pp.35-41, 2013 (Released:2013-12-05)

参考文献数

8

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労働現場では様々な自動生産機械が用いられ,重筋労働や有害環境下での労働から労働者を解放している.一方,自動生産機械による労働災害も数多く発生しているところである.本論文では,自動生産機械の操作について災害防止の観点から考察し,機械の操作には迅速に行うことが求められる操作(遅れることが許されない操作)と,落ち着いて行うことが求められる操作(早まることが許されない操作)があり,操作ボタンにはこれらの操作に適した色や形状があるが,この特性は「時間軸上の非対称性」として評価されることを示した.また,労働者が生産機械のリスクを受け入れるためには危害の大きさが十分に小さいか,又は危険からの回避行動が容易であることが求められるが,時間軸上の非対称性を高めることにより,自動生産機械が持つ危険の受容を容易にする可能性について示した.

著者

古谷 信彦 舘田 一博

出版者

日本環境感染学会

雑誌

環境感染 (ISSN:09183337)

巻号頁・発行日

vol.15, no.Supplement, pp.49-52, 2000-05-15 (Released:2010-07-21)

参考文献数

8

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抗酸菌, なかでも結核菌 (Mycobacterium tuberculosis) は1950年代までは罹患率, 死亡率とも高く, 死の病として恐れられていた. その後, 抗結核薬の登場や生活環境の改善に伴い罹患率, 死亡率は飛躍的に低下したが, 1980年代に入ってからその低下率に翳りがみえている. またそれに伴い病院内における集団感染例も増加してきている. 本菌の感染経路は空気感染であり, 感染の危険性は空気中に存在する結核菌含有飛沫核の濃度と, その空気に暴露される時間に依存して高くなる. 結核菌は初感染後, 初期変化群を形成するが, この初期変化群から引き続いて一次結核症に進展するものは感染例の5%にすぎない. 残りは発病に至らないが全身の諸臓器に持続感染し, 長時間を経てから二次結核症として発病する.

著者

長尾 茂人 近藤 誉之 中村 敬 中川 朋一 松本 禎之

出版者

日本神経学会

雑誌

臨床神経学 (ISSN:0009918X)

巻号頁・発行日

vol.56, no.4, pp.255-259, 2016 (Released:2016-04-28)

参考文献数

16

被引用文献数

4

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症例は43歳の男性である.亜急性に小脳失調症が出現し,ヒト免疫不全ウィルス(human immunodeficiency virus; HIV)感染症が確認された.小脳失調症の原因として,HIV脳症や二次性脳症を来たすウィルス,真菌,抗酸菌などの存在は否定的であった.一方で,自己免疫性小脳失調症と関連のある抗体である抗Yo抗体及び抗グリアジン抗体が検出された.HIV感染症では自己免疫現象がしばしば惹起されることが報告されている.HIV感染症に伴う小脳失調症では自己免疫機序による可能性を考慮する必要がある.

著者

相良 恒太郎 吉田 有貴子 西堀 正英 国吉 久人 海野 徹也 坂井 陽一 橋本 博明 具島 健二

出版者

日本魚類学会

雑誌

魚類学雑誌 (ISSN:00215090)

巻号頁・発行日

vol.52, no.1, pp.35-39, 2005-05-25 (Released:2010-06-28)

参考文献数

13

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A phylogenetic analysis, based on the complete nucleotide sequences of the mitochondorial control region (D-loop), was conducted on Mola mola occurring around the Japan coast. Two significantly distant clades (bootstrap value 914, based on 1000 replicates) were recognized. One consisted of 19 specimens with 812-814 by D-loop sequences that were collected from geographically wide spread locations around Japan (Aomori to Kagoshima). The other clade consisted of 3 specimens (all greater than 2 m in total length) collected from the Pacific coast of eastern Japan and characterized by 817 by D-loop sequences with many nucleotide substitutions compared with the former clade (ca.100 positions).

著者

Xi Li Akira Kitajima Tsuyoshi Habu Keiko Kataoka Rihito Takisawa Tetsuya Nakazaki

出版者

一般社団法人 園芸学会

雑誌

The Horticulture Journal (ISSN:21890102)

巻号頁・発行日

pp.MI-145, (Released:2016-06-15)

被引用文献数

1

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A new method of inducing fruit abscission by incubating detached ovaries and fruits in agar medium was developed in citrus. Ovary and fruit abscission in the satsuma mandarin, ‘Kiyomi’, hyuganatsu, and ponkan during early physiological fruit drop was characterized using this method. For primary physiological fruit drop, the abscission of detached ovaries could be divided into three patterns, including an early type in hyuganatsu, a medium type in ‘Kiyomi’, and a late type in satsuma mandarin and ponkan. The cumulative abscission ratio of four species and cultivars was over 80% at 96 h after treatment. However, for secondary physiological fruit drop, the initiation of fruit abscission was earliest in hyuganatsu, and latest in satsuma mandarin. The cumulative abscission ratio was highest in ponkan at 84% and lowest in hyuganatsu at 6%. The pattern of abscission was different for primary and secondary physiological fruit drop in the four species and cultivars. High temperature promoted the abscission of detached ovaries and fruits in satsuma mandarin and ponkan. Leaf attachment suppressed fruit abscission in ‘Kiyomi’, hyuganatsu, and ponkan at 7 weeks after anthesis in 2012 and ponkan at 5 weeks after anthesis in 2013. Ovary and fruit abscission in four species and cultivars during early physiological fruit drop was characterized by incubating detached ovaries and fruits in agar medium.

著者

二木 功治 西尾 和三 會田 信治 岡林 賢 中野 泰 竜崎 崇和 大曽根 康夫 鹿住 祐子

出版者

一般社団法人 日本内科学会

雑誌

日本内科学会雑誌 (ISSN:00215384)

巻号頁・発行日

vol.100, no.12, pp.3637-3639, 2011 (Released:2013-04-11)

参考文献数

5

被引用文献数

3 7

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症例は64歳,女性.咳嗽を主訴に近医受診.胸部CT上,多発小結節影および気管支拡張像が認められ,当院紹介受診した.気管支洗浄液にて抗酸菌陽性となり16S rRNAおよびrpoB遺伝子の相同性からMycobacteruim shinjukuenseと同定された.本菌株はTranscription Reverse-transcription Concerted method(TRC法)で結核菌群偽陽性を示した.クラリスロマイシン,リファンピシン,エタンブトール3剤併用療法を開始し,画像所見および自覚症状の改善が得られた.

出版者

公益社団法人 日本農芸化学会

雑誌

化学と生物 (ISSN:0453073X)

巻号頁・発行日

vol.36, no.10, pp.646-648, 1998-10-25 (Released:2009-05-25)

著者

手塚 武彦

出版者

一般社団法人 日本教育学会

雑誌

教育学研究 (ISSN:03873161)

巻号頁・発行日

vol.59, no.3, pp.386-387, 1992-09-30 (Released:2009-01-13)

著者

石原 英樹

出版者

一般社団法人 日本呼吸ケア・リハビリテーション学会

雑誌

日本呼吸ケア・リハビリテーション学会誌 (ISSN:18817319)

巻号頁・発行日

vol.25, no.2, pp.197-198, 2015-08-31 (Released:2015-10-06)

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COPD患者の在宅ケアには,薬物療法のみならず,包括的なアプローチが必要である.呼吸不全に対する代表的な在宅呼吸ケアメニューの一つである在宅酸素療法は,わが国でも広く普及・定着している.一方,高二酸化炭素血症を伴う患者の低酸素血症に対する治療は,酸素療法を中心に行われてきたが,肺胞低換気を認める患者には,酸素療法だけではなく,何らかの換気補助療法の必要性が指摘されていた.近年,高二酸化炭素血症を伴う患者に対する換気補助療法として非侵襲的陽圧換気療法(NPPV)が普及しつつある.NPPVには,従来の人工呼吸法にない簡便性・早期導入の容易さなどの利点があり,在宅NPPV症例数は急増傾向にある.また,円滑な在宅医療継続のためには,地域医療連携が必要である.地域とのネットワーク形成によって,医療・福祉の両面から総合的に支援することが可能になる.

著者

Kazuma HIROSAKA Katsumasa MIYAZAKI Motoki NAKANE Satoshi SAIGO Norihide TOHYAMA

出版者

一般社団法人日本機械学会

雑誌

Mechanical Engineering Journal (ISSN:21879745)

巻号頁・発行日

vol.3, no.3, pp.15-00683-15-00683, 2016 (Released:2016-06-15)

参考文献数

18

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A safety assessment needs to be conducted to analyze the damage caused by an aircraft impacting into a concrete structure at a nuclear power plant. One of the analytical methods used for this issue is a numerical impact simulation conducted after aircraft and reinforced concrete (RC) models are determined. We established the RC model and aircraft model in this study and confirmed the applicability of an impact simulation. Validation of our RC model was confirmed by conducting impact simulations of an F4 Phantom engine (GE-J79) crashing into three different wall thicknesses of 900, 1150, and 1600 mm. The damages to the wall in the simulations agreed with the test results conducted at Sandia National Laboratory around 1990. We also conducted parametric impact simulations of a rigid missile crashing into a concrete wall, changing the impact speed, mass of the missile, and the wall thickness. The wall thickness required to prevent perforation in the simulations was close to that estimated by the empirical formulae, although the residual speeds of the missile after the perforation in simulation did not agree very well to the values obtained by empirical formulae. One of the reasons of the difference in the residual speed is that the speed of the ejected concrete was not considered in our RC model. An impact simulation of an F4 Phantom crashing into a RC wall was conducted for the validation of our aircraft model. The shape of the impact load and the state of the frames of F4 Phantom on impact were almost the same as those in the test results conducted at Sandia, which showed that the F4 Phantom model was valid.

著者

Atsushi AKIIKE Sotaro KATSUMATA

出版者

グローバルビジネスリサーチセンター・東京大学MERC

雑誌

Annals of Business Administrative Science (ISSN:13474464)

巻号頁・発行日

vol.15, no.3, pp.149-161, 2016-06-15 (Released:2016-06-15)

参考文献数

18

被引用文献数

2

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The mobile phone market in Japan has a particular type of user, called a “dual product user,” who uses multiple mobile phones. Compared with other mobile phone users, dual product users possess a high level of consumer knowledge regarding mobile phones. Their ability to process information based on their high level of consumer knowledge may enable them to use multiple products. In fact, during our survey, the mobile phones (iPhones, other types of smartphones, and feature phones) had quite diverse characteristics. In addition, dual product users tended to use mobile phones for gaming. This is likely due to the high telecommunications fees levied on smartphones in Japan as well as the complicated structure of these fees. In assessing these characteristics, users with a high level of consumer knowledge consider their own patterns of usage when using multiple mobile phones for different purposes. These findings will increase the potential for marketing to target those with a high degree of such knowledge.

著者

Hiroki KIKUCHI Shumpei IWAO

出版者

グローバルビジネスリサーチセンター・東京大学MERC

雑誌

Annals of Business Administrative Science (ISSN:13474464)

巻号頁・発行日

pp.0160213a, (Released:2016-05-13)

参考文献数

17

被引用文献数

1 4

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Since the development of the idea of dynamic capabilities by Teece, Pisano, and Shuen (1997), it has been broadly discussed. However, there is no general view regarding the types of competencies that can be called dynamic capabilities. Teece et al. (1997) asserted that dynamic capabilities are one of the roles of organizational processes. Moreover, they asserted that organizational processes include static concepts, such as integration and coordination. This fact caused some confusion. Helfat and Winter (2011) contrasted the two concepts of operational and dynamic capabilities. They noted that the source of confusion was the fact that some competencies possess the nature of both concepts. In other words, three types of capabilities exist: pure operational, pure dynamic, and hybrid capabilities possessing both features. Helfat and Winter (2011) presented the example of corporate growth, such as an expansion in retail stores, an area where pure dynamic capabilities without any operational capabilities can be observed. Therefore, if pure dynamic capabilities are the pure competencies necessary for corporate growth, it is highly likely that these are the same competencies posited by Penrose (1959), who differentiated between economies of growth and economies of size. Takahashi (2015) conjectured that competencies that become resources unused for anything but growth are, more specifically, “competencies for start-up experts.”