著者

Ildikó V. TÓTH Inês C. SANTOS Cláudia F. M. AZEVEDO Jorge F. S. FERNANDES Ricardo N. M. J. PÁSCOA Raquel B. R. MESQUITA António O. S. S. RANGEL

出版者

(社)日本分析化学会

雑誌

Analytical Sciences (ISSN:09106340)

巻号頁・発行日

vol.29, no.5, pp.563-570, 2013-05-10 (Released:2013-05-10)

参考文献数

30

被引用文献数

3 5

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In this work, aiming to develop a simple, inexpensive method for the determination of low bromate levels in water samples, a liquid waveguide capillary cell (LWCC) was coupled to a FIA system. The long optical path (100 cm) of the LWCC was used to improve the sensitivity and the limit of detection without resorting to any off-line or in-line preconcentration processes. The spectrophotometric determination was based on the oxidation of chlorpromazine by bromate in an acidic medium, resulting in the formation of a colored radical product. Sulfamic acid was added to the reagent for minimizing the interference of nitrite, and a chelating ion exchange resin was used to remove major cationic interferences. The developed system allowed the determination of bromate within the range between 1 – 20 μg L−1 with a detection limit of 0.2 μg L−1.

著者

Shih-Yi Lin Cheng-Li Lin Wu-Huei Hsu I-Kuan Wang Chiz-Chung Chang Chiu-Chin Huang Chia-Hung Kao Shu-Hui Liu

出版者

(公社)日本産業衛生学会

雑誌

Journal of Occupational Health (ISSN:13419145)

巻号頁・発行日

pp.12-0263-OA, (Released:2013-04-09)

被引用文献数

1 8

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Background: Physicians are frequently studied as a population that experiences extremely high stress, burnout, and prolonged working hours that might harm one’s health. However, they have sound medical knowledge and have easy access to medical resources. We studied the incidence of cancer among Taiwanese physicians using a nationwide cohort study design. Methods: Data were obtained from the National Health Insurance (NHI) system in Taiwan. The physician cohort contained 22,309 physicians, and each physician was randomly frequency-matched according to age and sex with 4 people from the general population. Results: The overall incidence ratio of cancer was 27% lower in the physician cohort than in the nonphysician comparison cohort (33.9 vs. 46.5 people per 10,000 person-years, crude hazard ratio (HR) = 0.73, 95% CI = 0.70, 0.76). The adjusted HR was 0.78 (95% CI = 0.72, 0.84). Female physicians experienced a higher incidence rate ratio of overall cancer, compared to male physicians (crude HR = 1.17, 95% CI = 1.03, 1.33 vs crude HR = 0.70, 95% CI = 0.67, 0.74, respectively). Physicians were at a significantly higher risk of thyroid cancer (HR 1.75, 95% CI = 1.14, 2.68), prostate cancer (HR = 1.54, 95% CI = 1.21, 1.97), breast cancer (HR = 1.45, 95% CI = 1.00, 2.09), and non-cervical gynecological cancer (HR = 4.03, 95% CI = 1.77, 9.17), compared with the general population. Conclusion: Physicians are at lower overall risk of cancer than the general population, apart from cancer of the thyroid, prostate, breast, and non-cervical gynecological cancer.

著者

Fan Wang Chonglei Li Wei Liu Yihe Jin

出版者

日本毒性学会

雑誌

The Journal of Toxicological Sciences (ISSN:03881350)

巻号頁・発行日

vol.37, no.4, pp.739-748, 2012-08-01 (Released:2012-08-01)

参考文献数

46

被引用文献数

16 52

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Volatile organic compounds (VOCs) are the main substances causing multiple chemical sensitivity reactions in human. The effects of single VOCs exposure on airway inflammatory responses in mice lung have been reported. Previous studies have demonstrated the role of reactive oxygen species (ROS) in lung inflammation induced by single VOCs inhalation. However, effects of VOCs exposure on NO signaling and neurological signaling pathways in airway remain less clear. We exposed male Kunming mice to filtered air (0) and four types of VOCs mixture (formaldehyde, benzene, toluene, and xylene) treated air. Group 1 is 1.0, 1.1, 2.0 and 2.0 mg/m3, group 2 is 3.0, 3.3, 6.0 and 6.0 mg/m3, group 3 is 5.0, 5.5, 10.0 and 10.0 mg/m3, group 4 is 10.0, 11.0, 20.0 and 20.0 mg/m3, which respectively corresponded to 10, 30, 50 and 100 times of indoor air quality standard in China 2 hr per day, 5 days per week, for 2 weeks in the whole body exposure chamber. One day following VOCs exposure, we collected lung, bronchoalveolar lavage fluid (BALF) from each mouse and examined oxidative stress markers, cellular infiltration and production of cytokines, neurotrophin and substance P. We found that VOCs exposure influenced significantly NOS activity, GSH, or IL-6 concentration. The number of total cells, macrophages and eosinophils increased significantly in group 4. In addition, the production of interferon-gamma (IFN-γ) and substance P were significantly decreased. In contrast, neurotrophin-3 production in BALF was significantly increased in group 3 and 4. Our findings suggest that NO signaling pathways may induce airway inflammatory in short term VOCs exposure mice and the airway inflammatory response may be modulated by neurological signaling.

著者

大竹 宏之 久保田 一弘 直井 英雄

出版者

日本建築学会

雑誌

日本建築学会計画系論文集 (ISSN:13404210)

巻号頁・発行日

vol.76, no.659, pp.35-41, 2011-01-30 (Released:2011-03-07)

参考文献数

12

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In architectural planning, room space areas are mainly decided according to physical spaces such as human body sizes, occupant crowd densities, and the sizes of furnitures necessary for the room. However, human beings are also psychological entities and naturally require psychological spaces1), 2) as well. In former papers8) 12), we proposed a planning method of capacity and sizes of room under consideration to keep personal occupied areas. In this paper, we report the experimentally grasped distribution of allotted personal areas of occupant crowd to be used in the method, and the result of examination that the distribution can be approximated as Poisson distribution.

著者

黒柳 恒男

出版者

一般社団法人 日本オリエント学会

雑誌

オリエント (ISSN:00305219)

巻号頁・発行日

vol.7, no.3-4, pp.95-110,144, 1964 (Released:2010-03-12)

参考文献数

19

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Sufism played a great role in the classical Persian literature which flourished from the tenth century to the fifteenth century. We may regard a poet to be a Sufi by nature and a Sufi is incomplete without ecstacies of a poet.The first Persian Sufi poet was Abu Said Abi'l Khair who employed ruba'i form as a mode of Sufi expression. Sanai, Attar, Rumi and Jami expressed Sufism chiefly in mathnavi form.Persian Sufism found its highest expression in ghazal, the greatest exponent of which was Hafiz.The conventional symbolic language is characteristic of Sufi poetry. It is said that every object mentioned by Sufi poets is typal of some philosophic or Sufi conception.In this article I divided Sufi symbolic terms into the following five categories chiefly based on the great Sufi poet Iraqi's work.(A) Terms on the parts of human body.(B) Terms on wine(C) Terms on religion.(D) Terms on plants.(E) Terms on nature.(F) Terms on love.

著者

Ángel López-Cuenca Sergio Manzano-Fernández Francisco Marín Soledad Parra-Pallares Marina Navarro-Peñalver Salvador Montalban-Larrea Jose M. Andreu-Cayuelas Ana I. Romero-Aniorte Francisco Avilés-Plaza Mariano Valdés-Chavarri James L. Januzzi Jr

出版者

日本循環器学会

雑誌

Circulation Journal (ISSN:13469843)

巻号頁・発行日

pp.CJ-13-0106, (Released:2013-05-23)

参考文献数

24

被引用文献数

4 5

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Background: Beta-trace protein (BTP) and cystatin C (CysC) are novel biomarkers of renal function. We assessed the ability of both to predict major bleeding (MB) in patients with non-ST-segment elevation acute coronary syndromes (NSTE-ACS), compared to other renal function parameters and clinical risk scores. Methods and Results: We included 273 patients. Blood samples were obtained within 24h of admission. The endpoint was MB. During a follow-up of 760 days (411–1,098 days), 25 patients (9.2%) had MB. Patients with MB had higher concentrations of BTP (0.98mg/L; 0.71–1.16mg/L vs. 0.72mg/L, 0.60–0.91mg/L, P=0.002), CysC (1.05mg/L; 0.91–1.30mg/L vs. 0.90mg/L, 0.75–1.08mg/L, P=0.003), higher CRUSADE score (39±16 points vs. 29±15 points, P=0.002) and lower estimated glomerular filtration rate (eGFR; 66±27 vs. 80±30ml·min–1·1.73m–2, P=0.02) than patients without MB; there was no difference in creatinine level between the groups (P=0.14). After multivariable adjustment, both were predictors of MB, while eGFR and creatinine did not achieve statistical significance. Among subjects with eGFR >60ml·min–1·1.73m–2, those with elevated concentrations of both biomarkers had a significantly higher risk for MB. Net reclassification indexes from the addition of BTP and CysC to CRUSADE risk score were 38% and 21% respectively, while the relative integrated discrimination indexes were 12.5% and 3.8%. Conclusions: Among NSTE-ACS patients, BTP and CysC were superior to conventional renal parameters for predicting MB, and improved clinical stratification for hemorrhagic risk.

著者

溝口 勝

出版者

社団法人 農業農村工学会

雑誌

農業土木学会誌 (ISSN:03695123)

巻号頁・発行日

vol.60, no.8, pp.785-787, 1992-08-01 (Released:2011-08-11)

著者

栄 研二 海野 徹也 高原 泰彦 荒井 克俊 中川 平介

出版者

公益社団法人 日本水産学会

雑誌

日本水産学会誌 (ISSN:00215392)

巻号頁・発行日

vol.62, no.1, pp.46-50, 1996-01-15 (Released:2008-02-29)

参考文献数

14

被引用文献数

2

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Yearling ayu Plecoglossus altivelis collected in June and July from the Ohta River were biologically and biochemically examined in comparison with annual ayu caught in the same area.All the yearling ayu were female. The yearlng ayu were different in size and skin color from the annual ayu, but not different in anatomical parameters such as hepatosomatic index, intraperitoneal fat body ratio, and gonadosomatic index. The ovaries of annual ayu were immature and included chromatin nucleolus and perinucleolus stage eggs, but those of yearling ayu consisted mostly of abortive eggs and a few chromatin nucleolus and perinucleolus stage eggs.The yearling ayu had less muscle protein but more triglycerides than annual ayu. Fatty acid composition of muscle triglycerides in the yearling ayu was not different from that of the annual ayu. Low protein accumulation caused by depression of protein metabolism would affect the viability of yearling ayu after July.

著者

本條 均

出版者

一般社団法人 園芸学会

雑誌

園芸学研究 (ISSN:13472658)

巻号頁・発行日

vol.6, no.1, pp.1-5, 2007 (Released:2007-03-06)

参考文献数

30

被引用文献数

11 14

著者

今井 彬暁

出版者

日本文化人類学会

雑誌

日本文化人類学会研究大会発表要旨集 日本文化人類学会第47回研究大会 (ISSN:21897964)

巻号頁・発行日

pp.26, 2013 (Released:2013-05-27)

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本発表では、ベトナムの西北地方に位置するサパと呼ばれる観光地において形成されている民族間分業の様態を描き出し、そこでのモン族の立ち位置を彼らの労働表象に着目しつつ説明する。サパでは複数の民族が観光産業に携わっているが、経済活動に付与する価値付けは民族によって異なることを労働表象の民族的差異から説明し、そのことが民族間分業におけるモン族の現在の立ち位置を決定する要因となっていることを主張する。

著者

Yoshiki YUI Tetsuya SUMIYOSHI Kazuhisa KODAMA Atsushi HIRAYAMA Hiroshi NONOGI Katsuo KANMATSUSE Hideki ORIGASA Osamu IIMURA Masao ISHII Takao SARUTA Kikuo ARAKAWA Saichi HOSODA Chuichi KAWAI JMIC-B Study Group

出版者

日本高血圧学会

雑誌

Hypertension Research (ISSN:09169636)

巻号頁・発行日

vol.27, no.7, pp.449-456, 2004 (Released:2004-08-07)

参考文献数

19

被引用文献数

21 27

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We stratified findings from the Japan Multicenter Investigation for Cardiovascular Diseases-B according to whether or not the patients had diabetes and compared the incidence of cardiac events occurring over a 3-year period between treatment with nifedipine retard and angiotensin converting enzyme (ACE) inhibitor. The primary endpoint was the overall incidence of cardiac events (cardiac death or sudden death, myocardial infarction, hospitalization for angina pectoris or heart failure, serious arrhythmia, and coronary interventions), and the secondary endpoints were a composite of other events (cerebrovascular accidents, worsening of renal dysfunction, non-cardiovascular events, and total mortality). The results showed no significant difference in the incidence of the primary endpoint between the nifedipine group (n =199) and the ACE inhibitor group (n =173) in diabetic patients: 15.08% vs. 15.03%, relative risk 1.06, p =0.838. Also in nondiabetic patients, no significant difference was observed between the former (n =629) and the latter (n =649): 13.67% vs. 12.33%, relative risk 1.04, p =0.792. Similar results were obtained for the incidence of the secondary endpoints: in diabetic patients, 5.03% vs. 5.20%, relative risk 0.89, p =0.799; in nondiabetic patients, 2.70% vs. 2.47%, relative risk 1.07, p =0.842. Achieved blood pressure levels were 138/76 and 136/77 mmHg in the nifedipine group and 140/78 and 138/79 mmHg in the ACE inhibitor group in diabetic and nondiabetic patients, respectively. This study showed that nifedipine retard was as effective as ACE inhibitors in reducing the incidence of cardiac events in extremely high-risk hypertensive patients with complications of diabetes and coronary artery disease. (Hypertens Res 2004; 27: 449-456)

著者

Yoshiki YUI Tetsuya SUMIYOSHI Kazuhisa KODAMA Atsushi HIRAYAMA Hiroshi NONOGI Katsuo KANMATSUSE Hideki ORIGASA Osamu IIMURA Masao ISHII Takao SARUTA Kikuo ARAKAWA Saichi HOSODA Chuichi KAWAI JMIC-B Study Group

出版者

日本高血圧学会

雑誌

Hypertension Research (ISSN:09169636)

巻号頁・発行日

vol.27, no.3, pp.181-191, 2004 (Released:2004-10-19)

参考文献数

29

被引用文献数

70 103

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The Japan Multicenter Investigation for Cardiovascular Diseases-B was performed to investigate whether nifedipine retard treatment was associated with a significantly higher incidence of cardiac events than angiotensin converting enzyme inhibitor treatment in Japanese patients. The study used a prospective, randomized, open, blinded endpoint (PROBE) design. Patients were enrolled at 354 Japanese hospitals specializing in cardiovascular disease. The subjects were 1,650 outpatients aged under 75 years who had diagnoses of both hypertension and coronary artery disease. There were 828 patients subjected to intention-to-treat analysis in the nifedipine retard group and 822 patients in the angiotensin converting enzyme inhibitor group. The patients were randomized to 3 years of treatment with either nifedipine retard or angiotensin converting enzyme inhibitor. The primary endpoint was the overall incidence of cardiac events (cardiac death or sudden death, myocardial infarction, hospitalization for angina pectoris or heart failure, serious arrhythmia, and coronary interventions). The primary endpoint occurred in 116 patients (14.0%) from the nifedipine retard group and 106 patients (12.9%) from the angiotensin converting enzyme inhibitor group (relative risk, 1.05; 95% confidence interval, 0.81-1.37; p =0.75). In the Kaplan-Meier estimates, there were no significant differences between the two groups (log-rank test: p =0.86). The incidence of cardiac events and mortality did not differ between the nifedipine retard and angiotensin converting enzyme inhibitor therapies. Nifedipine retard seems to be as effective as angiotensin converting enzyme inhibitors in reducing the incidence of cardiac events and mortality. (Hypertens Res 2004; 27: 181-191)

著者

Suguru Yoshida Takamitsu Hosoya

出版者

(社)日本化学会

雑誌

Chemistry Letters (ISSN:03667022)

巻号頁・発行日

vol.42, no.6, pp.583-585, 2013-06-05 (Released:2013-06-05)

参考文献数

34

被引用文献数

57

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Arynes, generated in situ from o-(trimethylsilyl)aryl triflates by treatment with a fluoride, have been shown to react efficiently with various alkoxyphosphines via a mechanism similar to the Michaelis–Arbuzov reaction. Diverse aromatic oxophosphorus compounds, including derivatives with an ortho-ester function, have become easily available from a common aryne precursor by this method.

著者

菅原 泉 佐藤 明

出版者

日本森林学会

雑誌

日本森林学会大会発表データベース 第123回日本森林学会大会

巻号頁・発行日

pp.A25, 2011 (Released:2012-02-29)

著者

武井 典子 藤本 篤士 木本 恵美子 竹中 彰治 福島 正義 奥瀬 敏之 岩久 正明 石川 正夫 高田 康二

出版者

一般社団法人 日本老年歯科医学会

雑誌

老年歯科医学 (ISSN:09143866)

巻号頁・発行日

vol.23, no.4, pp.384-396, 2009-03-31 (Released:2011-02-25)

参考文献数

25

被引用文献数

3

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近年, 軽度の要介護高齢者の増加が厚生労働省より指摘され, 平成18年度の介護保険制度の改正では, 介護予防として口腔機能の向上が位置づけられた。また, 平成20年度の「後期高齢者医療制度」では, 食べる・話す・笑う機能を低下させないために「口腔機能の評価と管理」が位置づけられた。しかし, どちらも総合的な評価法や具体的な管理方法は, 社会科学的施策として確立されていない。このような現状から, 著者らは, 自立から要介護までのすべての高齢者のための介護状態の予防・軽減, QOLの向上などを目指した安全で有効な口腔機能の評価と管理のシステムの開発を試行し, 広く社会科学的に合理的な施策として実現すべく検討を試みてきた。今回はその第1報として, 自立高齢者を対象に, 口腔機能の総合的な検査法, その結果に基づいた改善法, その実施の有効性についての評価法を試行検討した。対象者は, 札幌市の某ケアハウスに入所している自立高齢者91名である。口腔機能を総合的に評価するために, 口腔の周り, 口腔の入り口 (咀嚼), 口腔の奥 (嚥下), 口腔の清潔度の4つのカテゴリーに分けて行った。その結果を活用して改善法を提案・実施・評価を行った。その結果, 咀嚼力の判定, 唾液湿潤度検査, 反復唾液嚥下テスト, オーラルデイアドコキネシス, カンジダ検査が有意に改善したことにより, 今回試作したシステムは, 自立高齢者の口腔機能の評価と向上に役立つ可能性が示唆された。

著者

大石 亘

出版者

農業情報学会

雑誌

農業情報研究 (ISSN:09169482)

巻号頁・発行日

vol.15, no.3, pp.319-330, 2006 (Released:2007-05-11)

参考文献数

17

被引用文献数

3 4

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線形計画法は営農計画の作成や農業技術の経営的評価などに活用されているが, Windowsで動作し手軽に線形計画法を活用することができる計算プログラムXLPを開発した. XLPはExcel用のアドインで, 起動時にExcelのメニューバーにメニュー [XLP] を作成する. 利用方法は, まずメニュー [XLP] - [新規ブック] でモデル記述シートを表示させ, 所定の形式で営農計画モデルを記述する. メニュー [XLP] - [LP計算] 等の計算メニューを選択すると, 最適解が整理されて計算結果シートに表示される. 計画モデルの記述は, 単体表による形式のほかに, 線形計画モデルの本来の記述形式である数式を利用できる. また, 単体表による形式では, 任意の列で折り返すことができるので, プロセス数がExcelの最大列数を超える計画モデルや, 営農部門ごとに折り返すなどの読みやすい計画モデルの記述が可能である. 基本的な営農計画モデルのサンプルデータが用意されており, メニュー [XLP] - [XLP_try] では線形計画法や営農計画モデルの作成方法の学習機能を提供している. このように, XLPは営農計画モデルを活用する際に手軽に線形計画法を利用できるツールに仕上がっている.

著者

海野 徳仁 伊藤 喜宏 五十嵐 俊博 長谷川 昭

出版者

公益社団法人 日本地震学会

雑誌

地震 第2輯 (ISSN:00371114)

巻号頁・発行日

vol.53, no.3, pp.263-268, 2001-03-25 (Released:2010-03-11)

参考文献数

25

被引用文献数

2 3

著者

山科 健一郎 中村 一明 福留 高明 佐藤 魂夫 田中 和夫

出版者

公益社団法人 日本地震学会

雑誌

地震 第2輯 (ISSN:00371114)

巻号頁・発行日

vol.38, no.1, pp.81-91, 1985-03-25 (Released:2010-03-11)

参考文献数

18

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Based on a few tens of photographs, height change of Kyuroku-shima Island, which locates very close to the focal region of the Japan Sea earthquake (M=7.7) on May 26th, 1983, is analyzed. 1) The island and adjacent small islets are considered to have subsided by about 30-40cm associated with the 1983 earthquake. The average offset obtained by 13 reliable photographs is 32±9cm. 2) Precursory deformation and secular change of the height were not found during 1964 through 1982. No detectable deformation was caused by largest aftershock (M=7.1) on June 21, 1983, and other aftershock activity. 3) Coseismic tilt and local collapse were not observed in the island. 4) In some cases, a height can be inferred even from snapshots with the error less than several percents. Crustal uplift and subsidence more than 10-20cm may be possible to be detected photographically at the seashore and lakeside.

著者

伊藤 潔 梅田 康弘 黒磯 章夫 村上 寛史 飯尾 能久

出版者

公益社団法人 日本地震学会

雑誌

地震 第2輯 (ISSN:00371114)

巻号頁・発行日

vol.39, no.2, pp.301-311, 1986-06-25 (Released:2010-03-11)

参考文献数

16

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The source characteristics of the Japan Sea earthquake, May 26, 1983 (M=7.7) is inferred from the seismic observation system with wide-frequency and large-dynamic range at the Abuyama Seismological Observatory. The duration of oscillation of the long-period low-gain seismogram (T0=25s) is much longer than those of other earthquake with nearly the same magnitude and nearly the same epicentral distance, which implies that the earthquake is a multiple shock. The relationship between a multiple shock and duration of oscillation is more clearly indicated in the figure of double amplitude envelope to eliminate the difference in amplitude by magnitude and focal mechanism. This simple method is applicable to detect multiple shocks in seismograms at one station, especially in historical seismograms with a few instrumental records.Seismograms of the main shock of the Japan Sea earthquake recorded by Wiechert seismographs and those of middle-period (T0=10s) low-gain velocity seismographs show a clear onset of the second event at about 22 seconds after the first arrival. Since no such second arrival is seen on the seismograms of the aftershocks at the same station, the phase is not a crustal phase but a P-wave arrival of the second event of the main shock.The main shock recorded by the middle-period low-gain velocity seismograph contains more complicated high frequency waves than the largest aftershock. This indicates that the rupture process of the main shock is much complicated compared with that of the aftershock. Further, comparing the spectrum of the first event of the main shock with that of the second event, the average amplitude at a low frequency (5-10 s) of the first event is smaller than the second event, while that at high frequency (1-2s) is larger than the second event. This suggests that the main shock is composed of double events of different rupture type; the rupture of the first event is smaller and radiated much high frequency waves than the second event.

著者

小菅 正裕 池田 仁美 鎌塚 吉忠 佐藤 裕

出版者

日本測地学会

雑誌

測地学会誌 (ISSN:00380830)

巻号頁・発行日

vol.32, no.4, pp.290-302, 1987-03-25 (Released:2011-07-05)

参考文献数

17

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A fault model of the 1983 Nihonkai-chubu (Japan Sea) earthquake (MJMA 7.7) was investigated on the basis of aftershock distributions, crustal deformation, and tsunami data. Since the earthquake took place under the sea off the coast of northwestern Tohoku District, there are a few land observation of crustal movement near the source area. We, therefore, have estimated the static fault parameters by comparing the wave form of observed tsunami with that of calculated from the static fault model. Trial fault parameters were derived from seismic data: focal mechanism solutions, seismic moment, and aftershock distributions with reference to the rupture process of the main shock. Our model was characterized by three fault planes trending NNE-SSW in the southern and the middle parts and NNW-SSE in the northern part, and by their low dipangle of 25°. The tsunami wave form was simulated numerically by a finite difference method. The fault model derived from seismic data reasonably explains the geodetic data and tsunamis. The calculated vertical deformation of land was consistent with the observed subsidence of 30-40 cm at Kyuroku island situated near the source area, and those of a few centimeters at Oga peninsula and Fukaura. The tsunami wave form observed at tide-gage stations along the coast of the Japan Sea was well simulated by our model as well as the model with higher dip angle. The data of strain step observed by extensometers installed in northern Japan support the low angle thrust event.