著者

Tatsuya ISHIDA Akira YOKOTA Yuka UMEZAWA Toshiya TODA Kazuhiko YAMADA

出版者

Center for Academic Publications Japan

雑誌

Journal of Nutritional Science and Vitaminology (ISSN:03014800)

巻号頁・発行日

vol.51, no.3, pp.187-193, 2005 (Released:2009-06-15)

参考文献数

25

被引用文献数

10 32

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The fermented milk, so-called “Caspian Sea Yogurt” in Japan, consists of two bacterial strains isolated from traditional Caucasusian fermented milk. In the present study, those strains were identified and characterized. Strain FC was Gram-positive, facultatively anaerobic cocci and strain FA was Gram-negative, aerobic rods. Phylogenetic analysis based on 165 rDNA sequences showed that strain FC formed a cluster with Lactococcus lactis strains and was most closely related to L. lactis subsp. cremoris. Strain FA was included in the genus Acetobacter cluster and was most closely related to A. orientalis. The DNA G+C con-tents of strain FC and strain FA were 39.2 and 51.6 mol%, respectively. Biochemical tests and DNA-DNA hybridization clarified that strain FC belongs to L. lactis subsp. cremoris and strain FA belongs to A. orientalis. The culture supernatant of lactococcal strain FC inhibited the growth of L. lactis subsp. cremoris DSM 20069T and L. lactis subsp. hordniae JCM 1180T. The inhibitory activity was detected after incubation at 70°C for 60min or 100°C for 30min and was stable when the supernatant was adjusted to a pH ranging from 4.9 to 7.5. The antimicrobial activity was lost on treatment with proteolytic enzymes such as proteinase K, trypsin, pronase, and pepsin, although it was not affected by catalase. The gene of lac-tococcin B (lcnB) homolog was found in the strain PC. From the above results, the strain PC was thought to produce a bacteriocin-like substance.

著者

Yasutsugu MIWA Makoto NAKATA Asuka KUROSAWA Hiroshi SASAI Nobuo SASAKI

出版者

公益社団法人 日本獣医学会

雑誌

Journal of Veterinary Medical Science (ISSN:09167250)

巻号頁・発行日

vol.70, no.12, pp.1323-1326, 2008 (Released:2009-01-01)

参考文献数

14

被引用文献数

2 11

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Adrenal diseases are quite common in Japanese pet ferrets; however, there have been no reports concerning the epidemiology of ferret adrenal disease in Japan. The purpose of this study was to collect epidemiological data on ferret adrenal disease in Japan by sending a questionnaire to veterinarians throughout Japan. Among the 521 cases that met the criteria for this study, 307 were adrenocortical carcinoma (58.9%), 117 were adrenocortical adenoma (22.5%) and 87 were adrenocortical hyperplasia (16.7%), respectively. Sex, clinical signs, concurrent diseases, age and the sites of the affected adrenal gland in these cases were similar to those reported in North America. Most pet ferrets in Japan are imported from North America, and their husbandry in Japan is similar to that in North America, which may be the cause of the similarity in ferret adrenal disease between North America and Japan. Because a difference in the incidence of ferret adrenal diseases among countries has been reported, further research is necessary to investigate the factors related to the similarities and how to decrease the incidence of adrenal diseases in ferrets in Japan.

著者

Nobuhito HAYASHIMOTO Hideaki YOSHIDA Kazuo GOTO Akira TAKAKURA

出版者

公益社団法人 日本獣医学会

雑誌

Journal of Veterinary Medical Science (ISSN:09167250)

巻号頁・発行日

vol.70, no.5, pp.493-495, 2008 (Released:2008-06-04)

参考文献数

12

被引用文献数

5 10 1

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We isolated Streptobacillus moniliformis, the causative agent of rat-bite fever in humans, from the salivary gland of a pet rat postmortem. The isolate was a Gram-negative pleomorphic coccobacillus, which produced acid from glucose and showed enzymatic activities for eight items in the API ZYM system. The results were consistent with those of the reference strain, ATCC 14647T, except for acid production from dextrin. Partial sequencing of 16S rRNA (1,440 bp) and gyrB genes (514 bp) of the isolate revealed similarities of 100% and 99.8%, respectively, to those of S. moniliformis in GenBank. Therefore, the isolate was identified as S. moniliformis. These results suggested the potential risk of rat-bite fever arising from pet rats in Japan.

著者

石垣 幸雄

出版者

日本アフリカ学会

雑誌

アフリカ研究 (ISSN:00654140)

巻号頁・発行日

vol.1977, no.16, pp.1-13, 1977-03-30 (Released:2010-04-30)

著者

加藤 百一

出版者

公益財団法人 日本醸造協会

雑誌

日本釀造協會雜誌 (ISSN:0369416X)

巻号頁・発行日

vol.73, no.10, pp.768-775, 1978-10-15 (Released:2011-11-04)

参考文献数

5

著者

渡邉 卓哉 石榑 清 藤岡 憲 堀場 隆雄 平井 敦 伊藤 洋一

出版者

日本臨床外科学会

雑誌

日本臨床外科学会雑誌 (ISSN:13452843)

巻号頁・発行日

vol.69, no.1, pp.175-178, 2008 (Released:2008-05-15)

参考文献数

13

被引用文献数

1 2 1

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症例は70歳,男性.幼少時より軽い臍炎を繰り返していた.平成4年4月,臍から下腹部腹壁に膿瘍を形成したため,尿膜管遺残膿瘍と診断され臍,尿膜管全摘術を施行された.病理組織学的検索で腺癌を認めたため,再手術により膀胱周囲の尿膜管遺残組織と思われる部分および膀胱頂部を追加切除されたが,癌組織は認められなかった.その後平成10年4月に臍摘出部の硬結,平成11年1月に右鼠径リンパ節の腫大,平成18年4月に右下腹部腹壁の硬結,両鼠径リンパ節の腫大をきたし,局所再発が疑われ腫瘍摘出術を施行された.いずれも病理組織学的検索で,再発と診断された.平成18年8月に両側多発肺陰影と縦隔リンパ節の腫大を認めたため,多発肺転移が疑われた.テガフール・ギメラシル・オテラシル配合剤による化学療法を8クール施行されたが,多発肺陰影の大きさは変化しておらず,現在も継続治療中である.

著者

泉沢 久美子

出版者

国立研究開発法人 科学技術振興機構

雑誌

情報管理 (ISSN:00217298)

巻号頁・発行日

vol.55, no.8, pp.571-581, 2012-11-01 (Released:2012-11-01)

参考文献数

4

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アジア経済研究所図書館では,50年以上にわたって開発地域の統計資料を網羅的に収集してきた。本稿では,これら資料の収集方法,コレクションの特色,整備・提供方法を説明するとともに,これまでの蔵書構築等を通じて把握してきた開発途上地域の公式統計の整備・公開状況と最近の動向について報告する。また,国際機関による国際比較統計の編纂状況と近年のオープン・データ政策について簡単に概説する。参考資料として主要な国際機関の統計情報一覧と調べ方ガイドを掲載する。

著者

Momoko TANIGAWA Yukita SATO Hiroko EJIRI Takayuki IMURA Rei CHIBA Hanae YAMAMOTO Makoto KAWAGUCHI Yoshio TSUDA Koichi MURATA Masayoshi YUKAWA

出版者

公益社団法人 日本獣医学会

雑誌

Journal of Veterinary Medical Science (ISSN:09167250)

巻号頁・発行日

pp.12-0359, (Released:2012-10-31)

被引用文献数

3 19

---

We investigated for the first time the prevalence of avian haemosporidia of genera Plasmodium, Haemoproteus, and Leucocytozoon among birds and mosquitoes on Tsushima Island of Japan, which is located between Japan and the Korean Peninsula. Of 55 wild birds belonging to 33 species, 16 (29.1%) tested positive for haemosporidia as follows: Plasmodium spp. (11/55; 20.0%); Haemoproteus spp. (2/55; 3.6%); and Leucocytozoon spp. (3/55; 5.5%). A genetic lineage isolated from the Eurasian Sparrowhawk (Accipiter nisus) was identical to that of the known avian malaria parasite P. circumflexum. Several genetic lineages were identical or closely related to the parasite lineages that were previously detected in birds and mosquitoes in Japan and Korea. Another single identical genetic lineage was also detected in both migratory and resident birds. A total of 753 mosquitoes from 12 species were collected; and one fully fed Aedes albopictus was positive for avian Plasmodium (1/753; 0.13%) which is identical to a genetic lineage detected in both mosquitoes in Japan and birds in Korea. Blood-meal identifications of blood-fed mosquitoes showed direct contact between the mosquitoes and 4 species of mammals including humans, cattle, rodents, and the endangered Tsushima leopard cat (Prionailurus bengalensis euptilura). Migratory birds use Tsushima Island as a site for wintering, breeding, and resting, and our results suggest the transmission of avian haematozoa between resident and migratory birds during their stay on Tsushima Island.

著者

和田 博夫 三雲 健 小泉 誠

出版者

公益社団法人 日本地震学会

雑誌

地震 第2輯 (ISSN:00371114)

巻号頁・発行日

vol.32, no.3, pp.281-296, 1979-09-25 (Released:2010-03-11)

参考文献数

28

被引用文献数

2 3

---

Seismicity in the northern Hida region, Japan, has been routinely observed since May, 1977 at telemeter-network stations of the Kamitakara Geophysical Observatory, and about 1500 local shocks with magnitudes greater than 0.5 have been located. (1) The observation reveals high seismicity along the Atotsugawa fault, along the northern Japan-Alps, south of Mt. Norikura and Mt. Ontake, and near Hida-Osaka, with focal depths shallower than 20km. (2) Seismic activity along the Atotsugawa fault is high at the eastern and western portions, with an intermittent zone of low activity, extending over 70km. Epicenters are deviated about 2-3km north of the fault trace, and this deviation together with focal depth distribution suggests a slightly northwestwardd dipping fault plane. All these shocks are confined above 13km, suggesting either that the fault plane extends down to this depth, or that minor brittle fractures do not take place under the depth due to some flow propertities of rock materials there. (3) Nine shocks along the fault show focal mechanisms consistent with right-lateral strike-slip evidenced by geological and geomorphological surveys (MATSUDA, 1966). (4) Heavy damage along the fault region at the time of the 1858 Hida earthquake (M=6.9) appears to indicate that this large earthquake was caused by faulting motion of the Atotsugawa fault. Most of the present seismic activity along the fault might be associated with some readjustments of residual stresses around there.

著者

原 武史

出版者

日本都市社会学会

雑誌

日本都市社会学会年報 (ISSN:13414585)

巻号頁・発行日

vol.1998, no.16, pp.57-72, 1998-07-25 (Released:2011-02-07)

参考文献数

29

著者

金井 淑子

出版者

公益財団法人 日本学術協力財団

雑誌

学術の動向 (ISSN:13423363)

巻号頁・発行日

vol.17, no.5, pp.5_40-5_45, 2012-05-01 (Released:2012-09-06)

著者

Manabu KOIKE Yasutomo YUTOKU Aki KOIKE

出版者

公益社団法人 日本獣医学会

雑誌

Journal of Veterinary Medical Science (ISSN:09167250)

巻号頁・発行日

pp.12-0112, (Released:2012-05-23)

被引用文献数

3 7

---

In clinical settings, cellular resistance to chemotherapy and radiotherapy is a significant component of tumor treatment failure. The mechanisms underlying the control of localization of DNA repair proteins play a key role in the regulation of DNA repair activity. The DNA repair protein XRCC4, which is a regulator of DNA ligase IV activity, might be a key contributor to chemoresistance to not only anticancer agents, e.g., etoposide, but also radioresistance. However, it is remains unclear whether XRCC4, which is a key player in nonhomologous DNA-end-joining (NHEJ), plays a role in low-dose radioresistance. In this study, we confirmed that human XRCC4 tagged with the enhanced green fluorescent protein (EGFP-XRCC4), as well as the DNA damage sensor Ku80 tagged with EGFP, mainly localized in the nuclei and its accumulation at DNA damaged sites began immediately after microirradiation. Moreover, we generated and characterized cell lines expressing EGFP-XRCC4 in XRCC4-deficient cells, i.e., XR-1 cells derived from the Chinese hamster ovary. Our findings showed that XR-1 cells were more sensitive than controls (CHO-K1) to low-dose X-irradiation (<0.5 Gy), whereas the radiosensitive phenotype of XR-1 cells was rescued by the expression of EGFP-XRCC4. We also confirmed that EGFP-XRCC4 expressed stably in XR-1 cells stabilizes DNA ligase IV. Altogether, these cell lines might be useful for the study of not only the dynamics and function of XRCC4, but also the molecular mechanism underlying the cellular resistance via the NHEJ pathway to low-dose radiation in mammalian cells.

著者

山本 泰朗 橘 真理 栄枝 弘司 岡崎 和一 山本 泰猛

出版者

一般財団法人 日本消化器病学会

雑誌

日本消化器病学会雑誌 (ISSN:04466586)

巻号頁・発行日

vol.81, no.6, pp.1489-1489, 1984 (Released:2007-12-26)

参考文献数

4

被引用文献数

2

著者

小原 慎弥 上原 隆志 木村 圭一郎 吉田 哲郎 藤原 翔平 水口 裕尊 布施 泰朗 山田 悦

出版者

公益社団法人 日本分析化学会

雑誌

分析化学 (ISSN:05251931)

巻号頁・発行日

vol.58, no.4, pp.231-240, 2009 (Released:2009-05-04)

参考文献数

16

被引用文献数

4 5

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2006年12月から琵琶湖水を採水し,湖水中の溶存有機物質(DOM)を疎水性樹脂(DAX-8)で疎水性酸(HoA),疎水性中性物質(HoN)及び親水性有機物質(Hi)にカラム分画し,DOM及びその画分の鉛直分布や月変化など動態解析を行った.DOMとその画分の鉛直分布は,5月までは水深に関係なくほぼ均一だが,夏季6~9月には水温躍層(水深10~20 m)の間で大きく変化した.表層水のDOM,Hi及びHoA濃度は,5~9月に増加し,水深の深い所との濃度差が大となった.これらが増加した春季から夏季にはクロロフィルの増加が見られ,フミン物質の増加に加えて内部生産によるHi濃度の増加が影響していると考えられる.トリハロメタン(THM)生成能は,水深10 m付近で高く,水深20 m以下では35~40 μg/Lの値で水深による変化は小さかった.培養時における藻類由来有機物の単位有機炭素当たりのTHM生成能はMicrocystis aeruginosa>Cryptomonas ovata>Staurastrum dorcidentiferumの順で,その種類によってかなり異なり,土壌起源のフミン物質のTHM生成能より低い値を示した.一方,生分解時における藻類由来有機物の単位有機炭素当たりのTHM生成能は,その種類による違いは少なく,湖水の値に近い値を示した.

著者

権藤 智之 上橋 由寛 松村 秀一

出版者

日本建築学会

雑誌

日本建築学会計画系論文集 (ISSN:13404210)

巻号頁・発行日

vol.75, no.647, pp.193-200, 2010-01-30 (Released:2010-04-02)

参考文献数

20

被引用文献数

1 1

---

In Okinawa, new wooden house construction starts is very small compared with in the whole Japan. So, wooden house builders in Okinawa have many difficulties, like shortage of lumbers or carpenters. But, from the 1990s, pre-cut lumber shipped from southern Kyushu area have got used in Okinawa. With this new building method, some companies which have no experience of wooden construction moved onto wooden house construction. Most of them build small numbers of wooden houses, and do another business on the other hand. And wooden house building system is influenced by limited distribution channel as well as environmental factor.

著者

Pierluigi IMBIMBO Lorenzo CASTIGLIEGO Andrea ARMANI Bartolomeo BIOLATTI Francesca Tiziana CANNIZZO Daniela GIANFALDONI Alessandra GUIDI

出版者

公益社団法人 日本獣医学会

雑誌

Journal of Veterinary Medical Science (ISSN:09167250)

巻号頁・発行日

pp.11-0489, (Released:2012-05-22)

被引用文献数

2 3

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A gross pathology and histological investigation was carried out on bovine target organs of anabolic substances in the Molise Region (Italy). One hundred forty-four bovines (12–24 months old, 123 males and 21 females) were included in the survey. Ante-mortem assessment on their behaviour and clinical examination was performed. After slaughtering, samples of prostate, Cowper’s glands, Bartholin’s glands, mammary gland, ovaries, thymus and thyroid were collected, inspected and processed for histopathology, as suggested in the guidelines of the Italian national program for residue surveillance (PNR). Overall, 15.3% of examined animals have been classified as “suspect,” whereas 44.4% as “uncertain” and the remaining 40.3% as “negative”. The most frequent lesion was a severe thymus atrophy with fat infiltration (15.4% of males and 14.3% of females), strongly suggesting the illegal use of corticosteroids.

著者

安中 正 太田 孝平 茂木 寛之 吉田 郁政 高尾 誠 曽良岡 宏

出版者

公益社団法人 土木学会

雑誌

海岸工学論文集 (ISSN:09167897)

巻号頁・発行日

vol.46, pp.341-345, 1999-10-20 (Released:2010-03-17)

参考文献数

4

被引用文献数

6

著者

比嘉 広樹 堂上 高司

出版者

公益社団法人 日本生体医工学会

雑誌

生体医工学 (ISSN:1347443X)

巻号頁・発行日

vol.46, no.1, pp.31-36, 2008-02-10 (Released:2008-09-29)

参考文献数

8

被引用文献数

1

---

A noncontact input interface using image processing for people with disabilities of the fingers, such as rheumatism, collagen disease, and osteoarthritis, has been developed. The input interface is simply composed of a CCD camera and PC. Taken with the CCD camera, the fingers were appropriately detected using image processing in this paper. An on-screen keyboard and control box were also made. In order to evaluate a performance of the input interface, three healthy subjects input some example sentences using it. From the experimental results, it was clear that the beginners could directly input them in Microsoft Word without any difficulty, and the input characteristics with the least error were experimentally shown in this paper.

著者

阿部 清彦 大和田 厚祐 大井 尚一 大山 実

出版者

一般社団法人 電気学会

雑誌

電気学会論文誌C(電子・情報・システム部門誌) (ISSN:03854221)

巻号頁・発行日

vol.127, no.7, pp.1036-1042, 2007-07-01 (Released:2007-09-01)

参考文献数

17

被引用文献数

1 2

---

We have developed an eye-gaze input system for people with severe physical disabilities, such as amyotrophic lateral sclerosis (ALS) patients. This system utilizes a personal computer and a home video camera to detect eye-gaze under natural light. The system detects both vertical and horizontal eye-gaze by simple image analysis, and does not require special image processing units or sensors. We also developed the platform for eye-gaze input based on our system.In this paper, we propose a new web browsing system for physically disabled computer users as an application of the platform for eye-gaze input. The proposed web browsing system uses a method of direct indicator selection. The method categorizes indicators by their function. These indicators are hierarchized relations; users can select the felicitous function by switching indicators group. This system also analyzes the location of selectable object on web page, such as hyperlink, radio button, edit box, etc. This system stores the locations of these objects, in other words, the mouse cursor skips to the object of candidate input. Therefore it enables web browsing at a faster pace.

著者

岸本 研志 米村 貴裕 広瀬 健一 長江 貞彦

出版者

一般社団法人 映像情報メディア学会

雑誌

映像情報メディア学会誌 (ISSN:13426907)

巻号頁・発行日

vol.55, no.6, pp.917-919, 2001-06-20 (Released:2011-03-14)

参考文献数

4

被引用文献数

5 11

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障害者福祉として, 視線を利用した入力装置が, さまざまな研究機関で開発されている.しかし, 特殊な機器や複雑な設定が必要であり, 瞳の微動に対応し難い等の問題点がある.そこで本研究では, これらの改善を試み, 普及しやすいシステムを試作した.