著者
岩井 恵理華 山本 泰 飯塚 普子 末光 正昌 久山 佳代 小宮 正道
出版者
公益社団法人 日本口腔外科学会
雑誌
日本口腔外科学会雑誌 (ISSN:00215163)
巻号頁・発行日
vol.67, no.11, pp.630-633, 2021-11-20 (Released:2022-01-20)
参考文献数
12

Dipeptidyl peptidase-4 (hereinafter referred to as DPP-4) inhibitors are used in diabetes therapy. They lower blood glucose by inhibiting DPP-4 and promoting insulin secretion. Here, we report a case of oral mucous membrane pemphigoid caused by the oral administration of a DPP-4 inhibitor. A 61-year-old female with gingival erosion and bleeding in the maxilla from the right first premolar to the left first premolar was referred to our department. On the first visit, redness, blisters, erosion, and the Nikolsky phenomenon were observed in the aforementioned region. A biopsy was performed for suspected pemphigoid. A histopathologicaldiagnosis of pemphigoid was obtained using HE staining and the fluorescent antibody method. The patient had diabetes and had been taking a combination drug containing vildagliptin (DPP-4 inhibitor) and metformin hydrochloride for two years and six months. We suspected that the pemphigoid was caused by the DPP-4 inhibitor. A request for a prescription modification was made to the internal medicine department, and the DPP-4 inhibitor was replaced with canagliflozin hydrate. The symptoms (redness, blisters, erosion, and the Nikolsky phenomenon) disappeared one month after suspension of the drug containing the DPP-4 inhibitor. Furthermore, relapse has not occurred in the 2 years since.
著者
杉田 慎之介 長谷川 純子 鈴木 英樹
出版者
一般社団法人 日本地域理学療法学会
雑誌
地域理学療法学 (ISSN:27580318)
巻号頁・発行日
pp.JJCCPT22016, (Released:2023-10-03)
参考文献数
28

【目的】積雪寒冷地在住高齢者の冬季と春季の生活空間変化および性別,フレイルの有無による生活空間の季節変化について明らかにすることを目的とした.【方法】対象は北海道当別町在住で高齢者クラブに所属している高齢者とし,冬季に基本チェックリストを実施し,ロバスト群とプレフレイル・フレイル群に分類した.さらに,冬季と春季で生活空間(Life-space assessment:以下LSA)を評価した.LSAの季節変化を全対象者,性別,フレイル分類でそれぞれ比較した.また,LSAによる最大到達範囲と外出頻度の変化について検討した.【結果】春季に比べ冬季のLSAは全対象者(p=0.004,95%CI 2.67-13.34),ロバスト群(p=0.038,95%CI 0.52-16.48)で有意に低値を示した.最大到達範囲と外出頻度の変化については主に「町内」と「町外」レベルでの変化が認められた.【結論】積雪寒冷地在住の高齢者に対する介護予防活動の提案は季節やフレイルの有無による影響を考慮する必要がある.
著者
山田 和政 山田 恵 伊藤 倫之 塩中 雅博 植松 光俊
出版者
理学療法科学学会
雑誌
理学療法科学 (ISSN:13411667)
巻号頁・発行日
vol.21, no.3, pp.205-208, 2006 (Released:2006-09-22)
参考文献数
8
被引用文献数
2

長期臥床高齢患者の理学療法におけるリスクマネージメントを骨密度の観点から検討した。70歳以上の長期臥床患者33名(寝たきり群)と大腿骨頚部骨折患者29名(骨折群)を対象(すべて女性)に,踵骨の音響的骨評価値を測定し,比較した。寝たきり群は,骨折群と比較して有意に低い値であった(p<0.001)。理学療法実施時,1) 臥床期間・年齢・体重(栄養状態)に関する情報を事前に収集し,2) 廃用性症候群と老化によって著しい骨密度の低下をきたしている事を念頭に置き,3) 転倒・転落はもちろん,それより小さな外力でさえも容易に骨折を引き起こす危険性を有している事を再認識して,プログラムを進めていくことが重要である。
著者
申 易澈 野秋 政希 大宮 喜文 林 吉彦
出版者
一般社団法人 日本建築学会
雑誌
日本建築学会技術報告集 (ISSN:13419463)
巻号頁・発行日
vol.20, no.44, pp.159-164, 2014-02-20 (Released:2014-02-20)
参考文献数
10

In this study, with the aim of collecting the quantitative knowledge about radiant heat controlled by trees, the experiment was conducted using the ICAL radiant panel that can reproduce the radiant heating of constant intensity. By using this experiment, we considered the correlation of the shape of the tree and the shielding effect of the radiant heat of trees. As a result, shielding effect of radiant heat by camellia was confirmed by experiments. That effect was especially observed to have large tendency near the trees. Transmittance of heat flux and the shielding ratio(1-φy) have almost the same value, it was confirmed by the correlation of transmittance of heat flux and the shielding ratio(1-φy). Therefore, trees shielding ratio is one simple indicator that assesses the incident of heat shielding effect of the trees.
著者
織田 利光
出版者
日本医科大学医学会
雑誌
日本医科大学雑誌 (ISSN:00480444)
巻号頁・発行日
vol.55, no.1, pp.29-37, 1988-02-15 (Released:2009-12-04)
参考文献数
26

One hundred and thirty-eight cries of 56 infants were examined during first 14 days after birth. Crying in neonates was classified into three types of situational cry: hunger cry, discomfort cry and pain cry, and the temporal patterns of each type of cry were investigated on the basis of the parameters of cry duration and cry interval. The following results were obtained:1) In the case of the hunger cry, the cry duration was 0.69±0.31s, the cry interval 0.32±0.25s and the number of cries 9.3 ± 2.9 times/10s. The coefficient of cry duration variance showed the minimum value (=0.44) among the three types of cry, indicating that a constant cry duration was characteristic of the hunger cry. The coefficient of the cry interval variance (=0.79) was almost the same as that for the pain cry, but was lower than that for the discomfort cry. A rhythmical crying pattern was found in 72.7% of the cases of the hunger cry, which suggested a correlation between the hunger cry and a rhythmical crying pattern.2) In the discomfort cry, the cry duration was 0.82±0.62s, the cry interval 0.41±0.32s, and the number of cries 6.7±2.6 times/10s. The maximum coefficients of variance were seen for the cry duration and the cry interval, showing that this type of crying was characterized by large variations in the parameters. A rhythmical crying pattern was seen in only 19.0% of the cases of the discomfort cry.3) In the pain cry, the cry duration was 1.06±0.75s, the cry interval 0.39±0.92s and the number of cries 5.6±2.1 times/10s. The cry duration showed the longest value. A rhythmical crying pattern was seen in only 12.2%.4) The cry duration of the hunger cry gradually decreased during first 8 days after birth. The cry duration of the pain cry did not change during first 5 days after birth, but decreased during 6 to 8 days after birth. The cry duration of the discomfort cry showed no sequential changes in these periods.From the results, it was evident that there were characteristics in the cry durations and intervals and also were the crying patterns of neonates in accordance with the situation of them and the number of days after birth, so it was suggested that these can serve as points to distinguish when the mother hears the infant crying.
著者
牛山 明
出版者
国立保健医療科学院
雑誌
保健医療科学 (ISSN:13476459)
巻号頁・発行日
vol.72, no.3, pp.224-232, 2023-08-31 (Released:2023-09-21)
参考文献数
28

我が国においてはデジタルトランスフォーメーションがうたわれているが,その実現においては高速大容量の通信が可能な技術が必要である.その中でも無線電波を使用した通信は重要な基盤といえよう.我が国では2020年に高速かつ大容量の通信が可能な第5世代の通信規格(5G)が導入されて,現在全国に展開されつつある.5G通信は第4世代よりもより高い周波数帯(6GHz帯,28GHz帯)を利用することで通信速度が第4世代より高速化され,その利点により自動車の自動運転技術,遠隔医療(遠隔手術)などの技術も導入される予定であり,私達の生活をさらに豊かにする可能性を秘めている.無線通信をする際には,当然ながら電波を利用することになる.また電力設備からの超低周波電磁波,テレビ・ラジオ放送による高周波電波も環境中での電磁環境を形成している.近年ではIH調理器の普及や,電気の充電のための無線電力伝送の実用化がみられるがいずれも電波の新しい利用形態である.これらの技術革新は私達の生活環境がますます電波や電磁環境によって溢れることを意味するため,市民の間にはこれらの電波が健康に影響を与えることに対する不安も一定程度存在する.一方で,科学的な根拠に基づき,生活環境中の電波の強さは管理されている実態もある.本稿では電磁環境の健康影響について現在の科学的根拠を整理し,電磁環境の健康に対するリスクを概説する.
著者
Kiyoshi Hotta Naohide Hashimura Masaki Takatsuka Tomoki Matsuyama Kouichirou Nakagawa Tsuneo Yabusako Shuhei Hosomi Yasuhiro Fujiwara
出版者
The Japanese Society of Internal Medicine
雑誌
Internal Medicine (ISSN:09182918)
巻号頁・発行日
vol.60, no.24, pp.3857-3864, 2021-12-15 (Released:2021-12-15)
参考文献数
23
被引用文献数
5

Objective Ceftriaxone (CTRX) is a widely used antibiotic because of its long plasma half-life and good tissue transmission. Many of the reported studies on CTRX-associated pseudolithiasis were performed in children. Although some studies have been published in adults, there are no studies limited to elderly people. The present study investigated CTRX-associated pseudolithiasis and explored its risk factors in the elderly. Methods We retrospectively reviewed 133 elderly patients (≥65 years old) treated with CTRX. Pseudolithiasis was defined as stones or sludge newly appearing in the gallbladder, as detected by computed tomography after the administration of CTRX. We evaluated the risk factors for pseudolithiasis using multivariate regression and inverse probability of treatment weighting analyses. Results Among the 133 patients, 24 (18%) developed CTRX-associated pseudolithiasis. In a multivariate analysis, the CTRX dose [odds ratio (OR) 4.54, 95% confidence interval (CI) 1.36-15.07, p=0.012] and CTRX treatment duration (OR 2.80, 95% CI 1.06-8.04, p=0.043) were significantly associated with pseudolithiasis formation. The cut-off value of the total CTRX dose associated with pseudolithiasis formation was 19 g. A propensity analysis determined that the frequency of pseudolithiasis was increased in patients treated with >19 g total CTRX compared with those who received ≤19 g in total (OR 4.06, 95% CI 1.45-11.32, p=0.008). Conclusion The incidence rate of CTRX-induced pseudolithiasis is high in elderly people, and the CTRX dose and CTRX treatment duration are significant risk factors for pseudolithiasis. A total dose of >19 g increases the likelihood of pseudolithiasis formation in elderly people treated with CTRX.
著者
荻野 綱男
出版者
計量国語学会
雑誌
計量国語学 (ISSN:04534611)
巻号頁・発行日
vol.33, no.1, pp.28-39, 2021 (Released:2022-06-20)

データには質的データと量的データがあるが,それとは異なる視点として,計量的な見方と非計量的な見方がある.本稿では,計量的な見方による日本語研究がどんなものであるか,用例調査,コーパス,多人数質問調査などを例にして,その概略を述べた.また,計量的な研究が現代日本語学で多く行われていること,そのような研究は,幅広い学問領域に共通の研究のしかたであることを述べた.統計学とはどんなものか,記述統計学,推測統計学,探索統計学に分類してそれぞれについて解説した.さらに,統計学的な見方と計量的な見方の関係について,統計学が理論的,基礎的なデータ分析方法を追及するのに対し,計量的な研究は応用的,実践的なデータ分析を志向するという立場から述べた.計量的な言語研究を目指す上では,調査が重視されるが,その際のポイントとして,調査計画の重要性と調査結果の解釈の重要性を述べた.
著者
吉澤 浩志
出版者
日本神経心理学会
雑誌
神経心理学 (ISSN:09111085)
巻号頁・発行日
vol.32, no.4, pp.301-310, 2016-12-25 (Released:2017-01-18)
参考文献数
27

左側頭葉にはWernicke領野とその周囲皮質,弓状束の一部,側頭葉前方部など,言語に重要な領域を数多く含む.それぞれの部位の損傷により特徴的な失語型をとり,失語症に伴って独特の読み書き障害を呈する.また局所脳損傷による純粋な読み書き障害の責任病巣として,従来から左角回を中心とする神経回路が重視されてきた.しかし本邦において,左側頭葉後下部損傷に伴う漢字に特異的な失読失書が数多く報告され,欧米圏からも語彙性失読失書の部位と想定された側頭葉下部がvisual word form areaとして数々の臨床報告と機能画像解析が示されてきた.以上から漢字と仮名は処理経路が異なることが明らかとなり,日本語における読み書きの二重回路説が提唱された.

1 0 0 0 OA 免疫学入門

著者
熊谷 勝男
出版者
日本歯内療法協会
雑誌
日本歯内療法協会雑誌 (ISSN:03895238)
巻号頁・発行日
vol.8, no.1, pp.1-20, 1987 (Released:2020-02-22)
参考文献数
4
著者
岩下 具美 前田 保瑛 髙橋 詩乃 岡田 まゆみ 三山 浩 島田 遼太郎 栁谷 信之
出版者
一般社団法人 日本臨床救急医学会
雑誌
日本臨床救急医学会雑誌 (ISSN:13450581)
巻号頁・発行日
vol.26, no.1, pp.24-30, 2023-02-28 (Released:2023-02-28)
参考文献数
16

背景:救急救命士が行う医行為の質を担保する体制として病院実習(実習)がある。 救急隊の生涯教育にかかわる長野赤十字病院救命救急センター(以下,センターと略す)の取り組みを報告する。改変前:対象はセンターを管内とする消防本部(本部)のみであった。実習は1日当たり1名を受け入れ,主な項目は静脈路確保であった。救急隊を対象とする勉強会(勉強会)は夕方に年2〜3回不定期に開催していた。改変後:対象は,実習が地域メディカルコントロール協議会に属する全3本部,勉強会はセンターが担当する医療圏にある全5本部とした。実習は1日当たり2〜3名/本部を受け入れ,救急車現場出動時の医師搭乗,他隊搬送事案の見学,救急科入院患者検討会の参加などを新規項目に加えた。病院救命士を調整役とした。勉強会は日勤帯に毎月定時開催とした。結語:実習・勉強会の刷新は救急隊活動の質向上と消防本部間格差の均等化に寄与した。
著者
高橋 令二 徳山 龍明
出版者
Japanese Society of Microbial Ecology / The Japanese Society of Soil Microbiology
雑誌
Bulletin of Japanese Society of Microbial Ecology(日本微生物生態学会報) (ISSN:09117830)
巻号頁・発行日
vol.8, no.2, pp.95-107, 1993-10-31 (Released:2009-10-05)
参考文献数
56
被引用文献数
1

Ammonia and nitrite-oxidizing bacteria contribute to nitrification, a part of the nitrogen cycle in natural environments. These bacteria are important since they decompose accumulated inorganic nitrogen compounds and toxic substances such as nitrogen oxides and consume (fix) of CO2, a factor implicated in global warming. Nitrosomonas europaea, a chemoautotrophic ammonia-oxidizing bacterium which contributes to the first stage of nitrification has been studied in detail. It oxidizes ammonia as the sole nitrogen source of nitrite via hydroxylamine as an intermendiate. It grows under completely inorganic conditions using energy (65kcal) produced by the oxidation of ammonia and atmospheric CO2, its sole carbon source. Its growth rate is thus quite low and no extensive biochemical studies have been conducted. This paper reviews recent studies on the ammonia-oxidizing system (ammonia and hydroxylamine oxidation) in Nitrosomonas europaea. Data obtained with two strains of Nitrosomonas including a pure isolated strain of Nitrosomonas sp. TK794 are presented.
著者
Masanao ICHIMATA Atsushi TOSHIMA Fukiko MATSUYAMA Eri FUKAZAWA Kei HARADA Ryuzo KATAYAMA Yumiko KAGAWA Tetsushi YAMAGAMI Tetsuya KOBAYASHI
出版者
JAPANESE SOCIETY OF VETERINARY SCIENCE
雑誌
Journal of Veterinary Medical Science (ISSN:09167250)
巻号頁・発行日
vol.85, no.11, pp.1231-1236, 2023 (Released:2023-11-18)
参考文献数
18

Retroperitoneal hemangiosarcoma (RPHSA) is a rare tumor in dogs with a poorly understood prognosis after surgery. The objectives of this study were to investigate the clinical features and prognosis of canine RPHSA that had undergone surgical resection. In this single-center, retrospective cohort study, we reviewed the medical records of dogs that had undergone surgical resection for retroperitoneal tumors and received a histopathologic diagnosis of HSA between 2005 and 2021. The median progression-free survival (PFS) and overall survival (OS) were 77.5 days and 168 days, respectively. In the present study, canine RPHSA had an aggressive biological behavior similar to visceral HSA. Further studies in larger canine populations are needed to evaluate the efficacy of adjuvant chemotherapy.
著者
Caterina PUCCINELLI Tina PELLIGRA Ilaria LIPPI Simonetta CITI
出版者
JAPANESE SOCIETY OF VETERINARY SCIENCE
雑誌
Journal of Veterinary Medical Science (ISSN:09167250)
巻号頁・発行日
vol.85, no.11, pp.1216-1225, 2023 (Released:2023-11-18)
参考文献数
60

Aims of our study were to evaluate the feasibility and diagnostic value of two-dimensional shear wave elastography in dogs with acute kidney injury, chronic kidney disease, and acute on chronic kidney disease, its correlation with renal functional (creatinine, urea), and prognostic parameters (serum calcium-phosphorus product, urinary output), and with contrast-enhanced ultrasound (qualitative and quantitative evaluation). The study was prospective. A group of healthy (Group A) and a group of nephropathic dogs (Group B) were included. Shear wave elastography was performed on the left kidney of the subjects of both groups; contrast-enhanced ultrasound was performed only in dogs with acute kidney injury and acute on chronic kidney disease. Sixty-four dogs were included (Group A, n=24; Group B, n=40). The renal stiffness values were significantly higher in Group B than Group A; optimal cut-off stiffness values for detection of renal pathology were: ≥1.51 m/sec (area under the curve, 0.84; 95% confidence interval 0.74–0.94) and ≥6.75 kPa (area under the curve, 0.84; 95% confidence interval 0.73–0.94). For contrast-enhanced ultrasound, a significant positive correlation was found between renal stiffness, area under the curve, and wash-out area under the curve values of cortex quantitative analysis. No correlations were found between renal stiffness and renal functional and prognostic parameters. Shear wave elastography showed diagnostic utility to detect renal abnormalities in dogs with acute kidney injury, chronic kidney disease and acute on chronic kidney disease, however, it could not differentiate between these different nephropathies.
著者
Jeong-Min LEE Youn-Seo JUNG Yeon-Ju KIM So-Young PARK Joong-Hyun SONG Kun-Ho SONG
出版者
JAPANESE SOCIETY OF VETERINARY SCIENCE
雑誌
Journal of Veterinary Medical Science (ISSN:09167250)
巻号頁・発行日
vol.85, no.11, pp.1226-1230, 2023 (Released:2023-11-18)
参考文献数
17

The objective of this study was to investigate the thromboelastography (TEG) variables and platelet count after Asian pit viper (Gloydius) envenomation in dogs compared with healthy control dogs. Ten dogs with snake envenomation and twenty healthy dogs were included. There was a significant decrease in G (P=0.017), maximum amplitude (MA) (P=0.012), angle value (P=0.041), platelet count (P<0.001, as well as an increase in K value (P=0.034) and R value (P=0.007) in dogs with snake envenomation. The results of this study revealed that dogs with Asian pit viper (Gloydius) envenomation showed a hypocoagulable state compared with healthy dogs. Our findings may support the use of TEG for diagnosing and monitoring coagulopathy after Asian pit viper (Gloydius) envenomation in dogs.