著者

藤本 珠笛

出版者

埼玉大学大学院人文社会科学研究科日本語専攻内 さいたま言語研究会

雑誌

さいたま言語研究 (ISSN:2432857X)

巻号頁・発行日

no.6, pp.32-45, 2022

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本稿は、複数形接尾辞「ら」「たち」の使い分けについて、コーパスを用いて使用実態の調査を行い、人称代名詞を中心にその特徴を考察するものである。調査の結果、「ら」においては三人称代名詞「彼」との共起が多く、排他性や客観性、謙譲の意などを示す性質がみられた。一方、「たち」では一人称代名詞「私」と多く共起し、同質性や親しみ表現などの特徴が挙げられた。これらのことから、「ら」「たち」の使い分けにおいて、話者と指示対象における心的距離との関連性を明らかにした。また、「彼たち」を用いにくい要因として、人称代名詞「彼」が指示代名詞から転用されたものであることを挙げ、考察を行った。以上を踏まえ、日本語学習者への指導に関して提案を行った。

著者

阿如汗畢力格

出版者

アジア教育学会

雑誌

アジア教育 (ISSN:18822088)

巻号頁・発行日

vol.16, pp.39-51, 2022 (Released:2023-03-02)

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In this study, the temple Gotosho, which was built in the Qing dynasty and was the largest place of training for Buddhist monks in the Inner Mongolia region, was examined. Furthermore, the transformation of religious policy and monk training that focused on the founding period as a turning point were clarified. The analysis is divided into two periods: prior to and after the founding of China.  In order to govern the Mongolian region in the late Qing dynasty, Emperor Kang xi used his deep faith in Buddhism as a policy, and built many Buddhist temples in the Mongolian region, and encouraged education in temples. Consequently, temple education became the main focus in the Mongolian region. The temple provided Buddhist education and trained many Mongolian monks. In the Republic of China, the Qing dynasty monk training system was continued and “separation of church and state” was the core of the Buddhist policy in the Mongolian region. In 1933, the advance of Japanese colonial medical hygiene began, clinics and doctor training centers were opened at the temple, and Japanese medical hygiene business was adopted.  During the founding period of China, the Chinese central government adhered to a policy of religious freedom and maintained the traditional training of monks. However, after socialist movements such as land reform, the sectarian Patriotic United Front, and the National Unity Movement, temples began to function as places for national unification and national education. There was an increase in the age of monks’ ordination, a decrease in the number of monks and scholars, and a transformation in the content of the education provided.

著者

林 三博

出版者

The Kantoh Sociological Society

雑誌

年報社会学論集 (ISSN:09194363)

巻号頁・発行日

vol.2010, no.23, pp.130-140, 2010-08-30 (Released:2015-06-12)

参考文献数

40

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The purpose of this article is to examine the trace of the popular cultural studies of Tsurumi Shunsuke. In late 1940s, Tsurumi started popular cultural studies based on scientific methodologies to go beyond the philosophy and philosophical language that had prevailed in wartime Japan and to produce results useful to people. In early 1960s, this scientific-theoretical approach to popular culture was transformed into a practical one to transcend the distance between intellectuals and the people. However, this second approach proved impossible in the face of the appearance of technological-poetical discursive formations in late 1960s. This result indicates the historical limits of Tsurumi's everyday thought.

著者

Takahiro YOKOYAMA Tatsuya ISHIKAWA Yosuke MOTEKI Takayuki FUNATSU Koji YAMAGUCHI Seiichiro EGUCHI Hayato YAMAHATA Buntou RO Takakazu KAWAMATA

出版者

The Japan Neurosurgical Society

雑誌

NMC Case Report Journal (ISSN:21884226)

巻号頁・発行日

vol.10, pp.115-119, 2023-12-31 (Released:2023-04-21)

参考文献数

18

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PulseRider (Cerenovus, Irvine, CA, USA) is a relatively novel device used for the treatment of wide-neck aneurysms with a coil-assisted effect. However, treatment options for recurrent aneurysms after PulseRider-assisted coil embolization remain controversial. Here we report a case of recurrent basilar tip aneurysm (BTA) treated with Enterprise 2 after PulseRider-assisted coil embolization. A woman in her 70s underwent coil embolization for a subarachnoid hemorrhage with ruptured BTA 16 years ago. Recurrence was detected at 6-year follow-up, and an additional coil embolization was performed. Nevertheless, gradual recurrence still occurred, and PulseRider-assisted coil embolization was performed without any complications 9 years after the second treatment. However, recurrence was detected once more at 6-month follow-up. Thus, stent-assisted coil embolization using Enterprise 2 (Cerenovus) through PulseRider was selected for angular remodeling. Enterprise 2 was deployed between the right P2 segment of the posterior cerebral artery (PCA) and basilar artery (BA) after an effective coil embolization, which achieved effective angular remodeling between the right PCA and BA. The patient's postoperative course was uneventful, and no recanalization was detected after half a year. Although PulseRider is effective for wide-neck aneurysm treatment, recurrence remains a possibility. Additional treatment using Enterprise 2 is safe and effective with the expectation of angular remodeling.

著者

Fumihiro SAGO Yusuke SAKAMOTO Kenko MAEDA Masaya TAKEMOTO Jungsu CHOO Mizuka IKEZAWA Ohju FUJITA Daiki SOMIYA Akira IKEDA

出版者

The Japan Neurosurgical Society

雑誌

NMC Case Report Journal (ISSN:21884226)

巻号頁・発行日

vol.10, pp.103-108, 2023-12-31 (Released:2023-04-21)

参考文献数

10

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In this study, we report a case of catastrophic propeller brain injury with large scalp defect treated with omental flap reconstruction.A 62-year-old man was accidentally caught in a powered paraglider propeller during maintenance. The rotor blades impacted the left part of his head. On arrival at the hospital, he presented with a Glasgow Coma Scale score of E4V1M4. On some areas on his head, skin was noticeably cut off, and the brain tissue out-slipped through an open skull fracture. Continuous bleeding from the superior sagittal sinus (SSS) and the brain surface was observed during emergency surgery. Massive bleeding from the SSS was controlled using a number of tenting sutures and hemostatic agents. We evacuated the crushed brain tissue and coagulated the severed middle cerebral arteries. Dural plasty using the deep fascia of the thigh was performed. The skin defect was closed using an artificial dermis. The administration of high-dose antibiotics has failed to prevent meningitis. Moreover, the severed skin edges and fasciae were necrotic. Plastic surgeons performed debridement and vacuum-assisted closure therapy to promote wound healing. Follow-up head computed tomography revealed hydrocephalus. Lumbar drainage was performed; however, sinking skin flap syndrome was observed. After removing the lumbar drainage, cerebrospinal fluid leakage occurred. We then performed cranioplasty with a titanium mesh and omental flap on day 31. After the surgery, perfect wound healing and infection control were achieved; however, severe disturbance of consciousness remained. The patient was transferred to a nursing home. Primary hemostasis and infection control are mandatory. An omental flap has been determined to be effective in controlling infection by covering the exposed brain tissue.

著者

小林 祥泰 山口 修平 山下 一也 小出 博巳 卜蔵 浩和 土谷 治久 飯島 献一 今岡 かおる

出版者

一般社団法人 日本老年医学会

雑誌

日本老年医学会雑誌 (ISSN:03009173)

巻号頁・発行日

vol.33, no.1, pp.22-26, 1996-01-25 (Released:2009-11-24)

参考文献数

14

被引用文献数

1 1

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社会的活動性と脳の老化の関係を明らかにする目的で, 社会的環境の異なる地域在住健常高齢者61名 (老人ホーム在住高齢者21名 (平均77.6歳), 地域在住老人会員40名 (平均76.7歳) を対象に, 老研式活動能力指標, 岡部式簡易知的尺度, Kohs' Block Design Test, Zung's self-rating Depression Scale (SDS), up & go 時間, 局所脳血流, 頭部MRI検査を施行し両群間の比較を行った. 結果: 高血圧などの脳卒中の危険因子については両群間に有意差を認めず, 脳MRI所見でも潜在性脳梗塞, 白質障害, 脳萎縮共に両群間で差を認めなかった. 全脳平均脳血流量も両群間で有意差を認めなかったが, 老研式活動能力指標では老人会群で有意に活動性が高かった. 岡部スコアおよび Kohs' IQは老人会群で有意に高値であった. また, SDSスコアが老人ホーム群で有意に高値であり, うつ状態の傾向にあることが示された. 運動能力に関する指標である up & go 時間は, 老人会群で有意に短かった. 結論: 脳卒中などの脳疾患既往のない健常高齢者において, 脳卒中の危険因子やMRI上の潜在性動脈硬化性脳病変に差がない場合, 社会的環境, ライフスタイルの差が脳の老化に対して大きな影響を与えていることが示唆された.

著者

Hiroshi OKETANI Katsumi HARIMAYA Teruaki ONO Kazushige TERADO Satoshi INOHA Satoshi O. SUZUKI Takato MORIOKA

出版者

The Japan Neurosurgical Society

雑誌

NMC Case Report Journal (ISSN:21884226)

巻号頁・発行日

vol.10, pp.109-113, 2023-12-31 (Released:2023-04-21)

参考文献数

19

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Lumbar canal stenosis (LCS) has been reported as a precipitating factor by which a tethered spinal cord, which is asymptomatic during childhood, develops into tethered cord syndrome (TCS) in adulthood. However, only a few reports on surgical strategies for such cases are available. A 64-year-old woman presented with unbearable pain in the left buttock and dorsal aspect of the thigh approximately 1 year ago. Magnetic resonance imaging showed cord tethering with a filar-type spinal lipoma and LCS due to the thickening of the ligamentum flavum at the L4-5 vertebral level. Five months after the decompressive laminectomy for the treatment of LCS, an untethering surgery was performed at the dural cul-de-sac at the S4 level. The severed end of the filum was elevated rostrally by 7 mm, and the pain subsided postoperatively. This case study shows that surgeries for both lesions should be indicated for adult-onset TCS triggered by LCS.

著者

岡本 高宏 吉田 有策

出版者

日本臨床外科学会

雑誌

日本臨床外科学会雑誌 (ISSN:13452843)

巻号頁・発行日

vol.82, no.1, pp.14-25, 2021 (Released:2021-07-31)

参考文献数

46

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副腎,後腹膜,縦隔に生じた腫瘍はホルモンを産生している場合がある.ホルモン産生腫瘍であることを的確に診断されずに手術を受ける患者は,手術中そして術後に大きな危険にさらされる懸念がある.担当医は,こうした稀な疾患があることを認識し,周術期の安全に努めなければならない.副腎皮質および髄質から分泌されるホルモンを測定して過剰産生の有無を評価するが,皮質系ホルモンではACTHやレニンとのバランスから診断することが肝要である.また,副腎以外の部位(後腹膜,縦隔等)に生じた腫瘍でもノルアドレナリンを過剰産生することがある.カテコールアミン産生腫瘍に対してはα遮断薬投与による周到な術前準備が必要である.コルチゾール産生腫瘍では健側副腎の機能回復までの相当な期間,グルココルチコイドの補充を要する.アルドステロン過剰症では負荷試験で診断を確定したのち,副腎静脈サンプリングにて病変部位診断を行う.

著者

影山 玲子 中澤 慎介 青島 正浩 藤山 俊晴 伊藤 泰介 戸倉 新樹 本田 哲也

出版者

公益社団法人 日本皮膚科学会

雑誌

日本皮膚科学会雑誌 (ISSN:0021499X)

巻号頁・発行日

vol.131, no.4, pp.707-711, 2021-04-20 (Released:2021-04-21)

参考文献数

9

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特発性後天性全身性無汗症(AIGA)の診断には,ミノール法を代表とするヨードデンプン反応を利用した温熱発汗試験が一般的である.通常,同試験では全身皮膚への試薬塗布が行われるが,全身への試薬塗布は患者・医療者双方にとって肉体的・時間的負担が大きい.当科ではそれらの問題を解決するため,同試験を12カ所のスポットで施行している(スポット法).スポット法により診断されたAIGA 30例の解析から,AIGAでの無汗・低汗部位として上腕・前腕・大腿・下腿の四肢で最も頻度が高いことが示唆された.

著者

數間 貴紀 新井 麻子 大谷 智子 老谷 嘉樹 鈴木 恵子 松永 保

出版者

東京女子医科大学学会

雑誌

東京女子医科大学雑誌 (ISSN:00409022)

巻号頁・発行日

vol.93, no.2, pp.67-72, 2023-04-25 (Released:2023-04-25)

参考文献数

10

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Tay-Sachs disease involves accumulation of GM2 gangliosides in lysosomes due to a metabolic disorder of brain-abundant gangliosides. In the infantile type, death typically occurs by 3 years of age. We report brain magnetic resonance imaging (MRI) abnormalities in a case of infantile Tay-Sachs disease. The 8-month-old patient had development delay and began regression at 1 year of age. A cherry-red fundus spot and low β-hexosaminidase A (Hex A) levels in leukocytes indicated GM2 gangliosidosis. Gene analysis identified homozygous pathogenic variants in the HEXA gene, leading to Tay-Sachs disease diagnosis.At 10 months of age, brain MRI showed age-appropriate myelination. At 1 year 9 months, T2-weighted imaging showed high intensity in the subcortical white matter, with delayed myelination. At 2 years 4 months, the cerebral white matter, putamen, caudate nucleus, thalami (except ventral), middle cerebellar peduncle, and dentate nucleus showed high intensity on T2-weighted imaging. At 5 years 8 months, cerebral and basal ganglia atrophy was observed. The caudate nucleus and putamen showed high intensity on T1-weighted images and low intensity on T2-weighted images. Unlike typical infantile Tay-Sachs characteristics, higher Hex A activity in this case probably contributed to a milder phenotype and myelination acquisition during infancy.

著者

篠原 英美 衞藤 薫 勝浦 美沙子 橋本 和典 佐藤 友哉 水落 清 西川 愛子 永田 智

出版者

東京女子医科大学学会

雑誌

東京女子医科大学雑誌 (ISSN:00409022)

巻号頁・発行日

vol.93, no.2, pp.62-66, 2023-04-25 (Released:2023-04-25)

参考文献数

14

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We report a case of pediatric Fabry disease in a girl whose pain was relieved and quality of life (QOL) improved with enzyme replacement therapy (ERT). Her father was diagnosed with Fabry disease based on the examination findings for pre-renal transplantation due to renal failure. Therefore, examinations were performed for her. Urinary mulberry bodies were positive, and the genetic analysis for α-galactosidase A (GLA) revealed a nonsense variant, leading to the diagnosis of pediatric Fabry disease. At 8 years of age, she presented with pain in the distal portion of the extremities and abdomen, which persisted despite oral carbamazepine. Therefore, ERT was provided. After initiation of ERT, blood lyso-Gb3 levels decreased, and extremity and abdominal pain improved. We asked her and her parent questions about QOL before and 12 months after the start of ERT. The European Quality of Life Five Dimension Youth showed improved scores for usual activities and pain or discomfort, and self-scoring of physical and mental condition on the European Quality of Life Visual Analogue Scale improved from 22 before ERT to 70 after 12 months of ERT. Pediatric Quality of Life also showed improved scores for physical and emotional functioning. Similar results were obtained by questioning the parent. Although the questionnaire is subjective and depends on the patient's physical condition at the time, we speculate that ERT improved QOL. Since the severity of clinical symptoms in women with Fabry disease varies, regular follow-up and appropriate intervention soon after the appearance of organ involvement are important to improve QOL and prevent complications.

著者

倉持 笑子 山田 洋輔 長谷川 久弥 丸田 沙也香

出版者

東京女子医科大学学会

雑誌

東京女子医科大学雑誌 (ISSN:00409022)

巻号頁・発行日

vol.93, no.2, pp.57-61, 2023-04-25 (Released:2023-04-25)

参考文献数

7

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Background: Surfactants are produced sufficiently after 34 weeks of gestation as the fetal lungs mature. The stable microbubble test (SMT) evaluates fetal lung maturity. However, late preterm infants sometimes present with severe respiratory distress and require appropriate respiratory care.Methods: We reviewed 42 late preterm infants who underwent the SMT with gastric aspiration upon admission to our neonatal intensive care unit. The gestational age was 35.3 (34.6-36.0) weeks, and the birth body weight was 2,181 (1,971-2,527) g. We classified the patients into the premature and mature groups based on the results of the SMT. We investigated the results of the SMT in late preterm infants and compared lung maturity with the maternal and neonatal respiratory clinical courses.Results: There were 12 infants in preterm group (28.6%). The gestational age of the premature group was significantly longer, and the Apgar scores were lower in the premature group. Mothers of the premature group had significantly more cases of gestational diabetes mellitus. Respiratory distress syndrome was significantly more frequent, and infants in the premature group required invasive ventilation more frequently.Conclusions: We found that a small number of neonates produced sufficient surfactant, even in late preterm infants. It is suggested that the production of surfactants is related to gestational diabetes mellitus more than gestational age, and the SMT is useful in late preterm infants.

著者

赤川 浩之

出版者

東京女子医科大学学会

雑誌

東京女子医科大学雑誌 (ISSN:00409022)

巻号頁・発行日

vol.93, no.2, pp.49-56, 2023-04-25 (Released:2023-04-25)

参考文献数

28

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Intracranial aneurysms (IA) cause subarachnoid hemorrhage (SAH), which has high mortality and morbidity rates when rupture occurs. The success of genome-wide association studies (GWASs) followed by phenotypic confirmation in transgenic mice has supported the implication of genetic factors in the formation of IA. For example, a Sox17-deficient mouse model was established based on previous GWAS findings, confirming the development of IA resulting in SAH following Sox17 deficiency. The most recent international GWAS identified over half of the disease heritability of IA, including 17 risk loci using more than ten thousand patients. The remaining proportion of heritability, the so-called missing heritability, can be explained by the effects of rare variants detected by next-generation sequencing (NGS). In this review, we discuss the current knowledge regarding genetic factors associated with IAs provided by GWAS and rare variant analysis using NGS.

著者

大木 文雄 ダールストローム アダム

出版者

北海道教育大学釧路校

雑誌

釧路論集 : 北海道教育大学釧路校研究紀要 (ISSN:02878216)

巻号頁・発行日

vol.第35号, pp.69-77, 2003-11

著者

キリスト品川教会 鬼頭梓建築設計事務所企画

出版者

キリスト品川教会

巻号頁・発行日

1994

著者

鬼頭梓 [著] 図書館計画施設研究所編

出版者

図書館流通センター

巻号頁・発行日

1989

著者

横瀬 拓也 山内 直揮 高橋 紘一

出版者

公益社団法人 日本化学会・情報化学部会

雑誌

ケモインフォマティクス討論会予稿集 第31回情報化学討論会 東京

巻号頁・発行日

pp.P9, 2008 (Released:2008-11-06)

参考文献数

5

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オペロンの下流に存在するターミネータ領域の探索を行った。RNAの構造解析に使用されるドットマトリックス法において、自由エネルギーを評価値として用いることで、ターミネータ領域探索法を構築した。E.coli K12の各遺伝子領域の下流60塩基配列のターミネータ解析を行ったところ、スコアの高いものと低いものがみつかった。前者はρ-非依存性、後者はρ-依存性ターミネータに相当するものと思われる。

著者

小野 太雅

出版者

九州大学

雑誌

若手研究

巻号頁・発行日

2021-04-01

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現在、インプラント治療で用いられる歯根膜を持たないインプラント体は、歯根膜由来のバリア機構や固有感覚が存在しないため、細菌感染を生じやすく、過度な咬合圧の原因となることもある。これらの欠点を補うため、歯根膜とインプラント体との複合体である「バイオハイブリッドインプラント(BioHI)」の開発が進められている。申請者は既に、バイオ3Dプリンタを応用し、未分化なヒト歯根膜由来細胞の細胞塊を三次元的に積層した歯根膜様のチューブ型構造体と、インプラント体との複合体の作製に成功している。そこで本研究では、この複合体をラットの顎骨内に移植することで、BioHIとして機能するかを検証することを目的とした。

著者

服部 陽介

出版者

日本パーソナリティ心理学会

雑誌

パーソナリティ研究 (ISSN:13488406)

巻号頁・発行日

vol.26, no.3, pp.244-252, 2018-03-01 (Released:2018-03-06)

参考文献数

25

被引用文献数

5 1

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先行研究において,思考抑制傾向とストレスフルな出来事の経験の組み合わせが反すう傾向を促す可能性が指摘されており,その背景には即時的増強効果の影響があると考えられてきた。本研究では,反すう傾向を考え込みと反省的熟考という2側面に分割し,思考抑制傾向,ストレス経験,反すう傾向の関係について検討を行った。大学生212名に対し,約3カ月の間隔で2回の調査を実施した。その結果,思考抑制傾向とストレス経験が,それぞれ独立に,考え込みを強めることが示された。この結果は,即時的増強効果とは異なる要因が,思考抑制傾向と反すう傾向を関係づける働きを担っている可能性を示している。思考抑制傾向と反すう傾向の関係を検討するうえでの今後の方向性について議論した。